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envelope_glycoprotein_H

Euk-Vir

Cervid_alphaherpesvirus_3

envelope_glycoprotein_H__YP_010087581__Cervid_alphaherpesvirus_3__2115790

Identity

Accession:
YP_010087581 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

71.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Cervid_alphaherpesvirus_3

TaxID: 2115790

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 21-112
PDB
D2 high residues 654-790
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 56.0 5.10e-15 99.3% 90.8%
D3 medium residues 207-328
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA01 3.30.500.50 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › 0.78 55.0 4.75e-01 87.7% 49.4%
1p6pA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.74 36.0 3.60e-01 77.9% 45.6%
3imhA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.66 49.0 3.62e-01 78.7% 94.9%
2rcqA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.65 33.0 3.18e-01 77.9% 41.8%
1av4A03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.65 49.0 3.40e-01 80.3% 85.8%
3bvxA04 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.64 52.0 4.02e-01 87.7% 85.0%
2eabB01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.64 53.0 4.20e-01 89.3% 80.2%
6fopA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.63 51.0 4.15e-01 86.1% 71.7%
1mmuA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.63 47.0 3.41e-01 77.0% 90.6%
5e1qB01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.62 52.0 4.06e-01 91.8% 93.1%
1v7wA01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.62 52.0 3.94e-01 92.6% 89.7%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.61 49.0 4.25e-01 86.1% 88.3%
1a2vA03 2.70.98.20 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Copper amine oxidase, catalytic domain 0.61 47.0 3.24e-01 82.8% 86.8%
3w7tA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.61 45.0 3.66e-01 77.9% 79.3%
1nkgA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.60 51.0 4.08e-01 94.3% 89.2%
3eb8B01 3.10.450.460 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › EspG protein, N-terminal domain 0.57 27.0 3.65e-01 75.4% 86.9%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.57 32.0 3.27e-01 77.0% 55.8%
2ffsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 41.0 3.92e-01 82.0% 66.2%
5gv0A00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.52 39.0 3.55e-01 77.9% 65.4%
4h0aA00 3.40.33.10 Alpha Beta › 3-Layer(aba) Sandwich › Pathogenesis-related Protein p14a › CAP 0.52 44.0 3.38e-01 93.4% 89.7%
5e1qA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 33.0 3.75e-01 81.1% 82.3%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 40.0 3.87e-01 81.1% 80.7%
1vr8A00 3.40.1000.20 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › TM1622-like 0.52 40.0 3.87e-01 81.1% 88.9%
2ovsA00 2.40.128.380 Mainly Beta › Beta Barrel › Lipocalin › T3SS negative regulator GrlR 0.51 35.0 3.58e-01 77.0% 72.9%
1ealA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.50 35.0 3.44e-01 73.8% 67.7%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1554358 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.91 86.0 5.30e-01 100.0% 20.4%
2095476 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.89 82.0 5.13e-01 100.0% 20.6%
119302 3146.1.1.0 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain 0.77 56.0 4.00e-01 90.2% 27.4%
5001279 2004.1.1.308 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_21 0.68 39.0 2.80e-01 82.8% 20.0%
3223040 12.3.1.13 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Glyco_hydro_38C 0.67 53.0 4.19e-01 85.2% 93.7%
2095503 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.66 60.0 3.93e-01 100.0% 31.0%
3990496 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.64 37.0 4.74e-01 81.1% 100.0%
2389389 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.64 51.0 4.24e-01 86.1% 74.4%
3222216 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.64 31.0 3.97e-01 77.9% 80.0%
4989818 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.62 52.0 4.32e-01 91.8% 92.3%
3418904 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.60 32.0 3.52e-01 80.3% 62.0%
5035423 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.60 29.0 3.46e-01 100.0% 65.9%
2027 12.3.1.17 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › RhgB_N 0.60 51.0 4.08e-01 93.4% 89.2%
3588455 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.60 27.0 3.54e-01 74.6% 74.3%
3258614 12.3.1.40 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › TREH_N 0.59 49.0 4.30e-01 90.2% 93.0%
3945984 5084.5.1.22 ↗ beta barrels › Outer membrane meander beta-barrels › Porins › Porin › DUF3971 0.57 49.0 3.17e-01 94.3% 22.4%
3191832 12.3.1.36 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › DUF5127 0.57 45.0 3.54e-01 85.2% 89.8%
5014686 809.2.1.0 ↗ a+b two layers › BLIP-like › BT0923-like › BT0923-like 0.56 26.0 3.49e-01 89.3% 90.9%
3596915 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.56 42.0 2.72e-01 78.7% 30.7%
4951804 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.56 44.0 4.19e-01 82.8% 97.1%
3188851 9.14.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Uncharacterized protein YLR301W › Uncharacterized protein YLR301W › HRI1 0.54 38.0 3.98e-01 100.0% 79.1%
3953943 9.27.1.1 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH › Myco_19_kDa 0.54 39.0 4.07e-01 91.0% 81.8%
4008697 5084.5.1.22 ↗ beta barrels › Outer membrane meander beta-barrels › Porins › Porin › DUF3971 0.53 44.0 3.31e-01 92.6% 35.2%
4960626 4252.1.1.0 ↗ beta barrels › AttH-like › AttH-like › AttH-like 0.53 38.0 3.67e-01 74.6% 83.5%
3962450 9.27.1.0 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH 0.53 39.0 4.16e-01 91.0% 87.6%
1171964 809.2.1.0 ↗ a+b two layers › BLIP-like › BT0923-like › BT0923-like 0.53 23.0 3.18e-01 88.5% 82.8%
1171961 809.2.1.0 ↗ a+b two layers › BLIP-like › BT0923-like › BT0923-like 0.52 24.0 3.13e-01 89.3% 77.8%
3812869 284.1.3.0 ↗ a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain 0.51 36.0 3.94e-01 73.0% 99.0%
7054 881.2.1.1 ↗ a+b three layers › Mog1p/PsbP-like › TM1622-like › TM1622-like › DUF3242 0.50 38.0 3.82e-01 80.3% 94.5%
2552758 9.1.1.24 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin_7 0.50 34.0 3.31e-01 81.1% 62.0%
D4 medium residues 329-432
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_068353__Suid_alphaherpesvirus_1__10345__D240-339
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.81 61.0 6.64e-01 85.6% 94.2%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 66.0 6.83e-01 86.5% 91.8%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 53.0 6.11e-01 85.6% 94.6%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.80 59.0 6.47e-01 85.6% 94.1%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.79 65.0 6.25e-01 86.5% 76.3%
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.78 55.0 5.37e-01 85.6% 66.7%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.78 53.0 5.09e-01 85.6% 62.1%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.76 60.0 6.24e-01 86.5% 90.5%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.75 49.0 5.52e-01 84.6% 88.6%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 57.0 5.85e-01 83.7% 84.2%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 59.0 6.14e-01 86.5% 93.6%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.74 58.0 5.91e-01 84.6% 84.3%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.74 61.0 4.96e-01 87.5% 58.2%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 59.0 5.41e-01 86.5% 70.6%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.73 60.0 5.09e-01 86.5% 69.5%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.73 62.0 5.48e-01 91.3% 73.5%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.72 52.0 5.39e-01 88.5% 80.8%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 60.0 4.90e-01 91.3% 60.4%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 54.0 4.74e-01 86.5% 53.9%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.71 64.0 5.03e-01 100.0% 71.8%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.71 49.0 4.25e-01 71.2% 57.4%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.70 62.0 5.78e-01 98.1% 81.1%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 56.0 5.73e-01 86.5% 88.2%
3nrxA00 1.20.58.1520 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 57.0 5.41e-01 88.5% 74.0%
2ra1A01 1.20.58.790 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 56.0 5.80e-01 86.5% 94.9%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 55.0 5.45e-01 86.5% 86.4%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.69 61.0 5.75e-01 98.1% 86.6%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 49.0 4.33e-01 74.0% 64.0%
3pjaJ01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.69 62.0 5.78e-01 100.0% 79.4%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.68 55.0 5.04e-01 86.5% 74.1%
3swhA01 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.68 61.0 5.24e-01 99.0% 84.8%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 54.0 5.22e-01 85.6% 88.9%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.68 61.0 5.35e-01 100.0% 79.4%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 55.0 5.27e-01 87.5% 85.0%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 47.0 4.13e-01 72.1% 58.6%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 50.0 4.69e-01 80.8% 64.1%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 52.0 4.28e-01 100.0% 46.5%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 52.0 5.15e-01 84.6% 89.0%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 54.0 5.19e-01 87.5% 83.8%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.66 54.0 5.11e-01 87.5% 75.8%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 53.0 5.24e-01 86.5% 89.9%
2iakA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 53.0 4.32e-01 86.5% 46.9%
2yv9B02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 58.0 5.40e-01 100.0% 80.6%
1dowA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 53.0 4.24e-01 87.5% 44.9%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.65 56.0 5.26e-01 95.2% 96.1%
6k6iA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 53.0 4.17e-01 88.5% 47.5%
1qqtA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.65 53.0 4.86e-01 89.4% 67.4%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 56.0 5.44e-01 100.0% 87.7%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 51.0 5.09e-01 86.5% 90.8%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 53.0 5.26e-01 100.0% 85.7%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 54.0 5.32e-01 100.0% 87.6%
3qc1A01 1.25.40.540 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family 0.63 57.0 5.02e-01 100.0% 70.9%
4p9tA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 49.0 4.74e-01 88.5% 73.3%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 49.0 4.94e-01 85.6% 89.2%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 55.0 5.33e-01 100.0% 87.9%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 50.0 4.92e-01 100.0% 82.1%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 52.0 4.43e-01 91.3% 70.5%
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 42.0 3.80e-01 71.2% 59.2%
1hqoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 55.0 5.11e-01 100.0% 82.4%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 53.0 5.17e-01 100.0% 88.4%
4xaiB02 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.61 42.0 3.37e-01 70.2% 100.0%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 50.0 4.17e-01 89.4% 92.7%
2hfiA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.60 50.0 4.73e-01 91.3% 79.7%
3rc3A05 1.20.58.1080 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 45.0 4.40e-01 98.1% 75.2%
4ie5A02 1.20.58.1470 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain 0.58 47.0 4.35e-01 88.5% 72.4%
2iaiA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 49.0 4.48e-01 91.3% 69.9%
4g10A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.58 50.0 4.61e-01 100.0% 74.3%
2irmA00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.56 48.0 3.41e-01 95.2% 49.0%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.54 35.0 3.92e-01 79.8% 88.5%
1np7A02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.53 39.0 3.74e-01 86.5% 67.2%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.53 38.0 3.62e-01 95.2% 62.7%
1q6aA00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.51 42.0 4.18e-01 92.3% 85.0%
ECOD (90)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3576710 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.87 57.0 6.31e-01 89.4% 82.4%
4995305 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.83 65.0 6.86e-01 83.7% 89.5%
3884665 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.81 60.0 5.41e-01 87.5% 57.9%
5050794 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.81 64.0 6.75e-01 85.6% 91.6%
3648687 604.12.1.89 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › CDP-OH_P_transf 0.80 62.0 6.47e-01 85.6% 88.4%
3621681 604.1.1.139 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF7799 0.80 63.0 6.60e-01 83.7% 89.5%
3924665 604.1.1.136 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_7 0.80 66.0 6.64e-01 86.5% 93.3%
3596375 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.80 65.0 6.06e-01 85.6% 87.2%
3815026 604.1.1.148 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.80 57.0 6.23e-01 80.8% 90.6%
3533309 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.79 64.0 6.43e-01 86.5% 83.8%
3917600 604.1.1.6 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_4 0.79 66.0 6.24e-01 87.5% 76.7%
3615985 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 64.0 6.30e-01 85.6% 84.5%
3641718 604.5.1.52 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › DUF7610 0.79 58.0 6.53e-01 84.6% 100.0%
3224585 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.78 63.0 6.22e-01 86.5% 80.0%
3924651 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.78 63.0 6.57e-01 86.5% 92.6%
3453715 603.1.1.118 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF7610 0.78 60.0 6.46e-01 87.5% 93.3%
3892492 604.1.1.66 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_1st_PEPL 0.78 64.0 6.32e-01 86.5% 83.6%
4942736 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.78 63.0 6.35e-01 86.5% 95.2%
3992590 603.1.1.110 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 0.78 64.0 6.52e-01 86.5% 92.0%
3265125 604.22.1.1 ↗ alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N 0.77 56.0 5.24e-01 85.6% 62.4%
3500905 604.13.1.1 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.77 56.0 5.24e-01 85.6% 62.4%
3920960 604.8.1.2 ↗ alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Mitofilin 0.77 62.0 5.77e-01 86.5% 76.2%
3924662 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 59.0 6.19e-01 86.5% 89.5%
3992995 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.76 60.0 6.12e-01 86.5% 84.5%
3171100 603.1.1.100 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.76 62.0 6.37e-01 86.5% 94.0%
3934749 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.76 60.0 5.48e-01 86.5% 64.4%
4981185 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.76 62.0 5.18e-01 87.5% 95.4%
3786136 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.76 61.0 5.92e-01 87.5% 76.5%
3505493 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 60.0 5.67e-01 86.5% 70.4%
3276921 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.76 61.0 5.42e-01 86.5% 61.4%
3605285 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 59.0 5.24e-01 87.5% 59.3%
5046163 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.75 60.0 5.49e-01 86.5% 65.2%
3927006 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.75 60.0 6.38e-01 85.6% 96.7%
3214189 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 61.0 6.14e-01 87.5% 94.3%
3171345 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 59.0 4.92e-01 86.5% 48.9%
5043625 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 60.0 5.32e-01 86.5% 64.7%
3526861 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.75 59.0 5.82e-01 87.5% 79.1%
3915047 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 59.0 5.96e-01 86.5% 83.8%
3224980 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.74 57.0 6.20e-01 85.6% 98.8%
3404638 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.74 60.0 6.11e-01 86.5% 88.0%
3240501 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.74 60.0 5.42e-01 86.5% 67.9%
3488077 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.74 60.0 6.27e-01 86.5% 94.7%
3476130 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.74 58.0 5.23e-01 85.6% 61.4%
3312398 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.74 54.0 4.58e-01 85.6% 47.9%
4511937 603.1.1.139 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE_C, PF27021 0.74 64.0 5.58e-01 92.3% 100.0%
3577228 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 59.0 5.76e-01 87.5% 82.6%
3625675 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 59.0 5.51e-01 88.5% 71.2%
3498656 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 57.0 6.11e-01 87.5% 96.7%
3214883 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.72 59.0 5.06e-01 86.5% 60.0%
3351015 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.72 58.0 4.88e-01 86.5% 51.4%
3706209 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 57.0 5.11e-01 85.6% 60.7%
4112769 5069.1.1.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.72 60.0 5.73e-01 88.5% 81.7%
3936693 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 58.0 5.96e-01 93.3% 91.0%
3473134 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.72 58.0 4.90e-01 87.5% 70.9%
3793885 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.72 58.0 5.17e-01 86.5% 65.5%
3676370 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 65.0 4.49e-01 100.0% 43.8%
4134971 603.1.1.225 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, PF26585 0.71 64.0 5.31e-01 100.0% 81.1%
3623280 603.1.1.110 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 0.71 64.0 5.21e-01 100.0% 85.6%
4453744 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.71 53.0 5.23e-01 87.5% 74.5%
3307044 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 53.0 5.38e-01 86.5% 80.0%
3241687 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 57.0 5.55e-01 87.5% 81.7%
5058032 2485.1.1.0 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.70 63.0 5.19e-01 100.0% 75.1%
3408992 109.4.1.403 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Foie-gras_1 0.70 62.0 5.08e-01 95.2% 69.4%
3588128 4121.1.1.1 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.70 56.0 4.27e-01 86.5% 42.5%
3699649 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 61.0 5.26e-01 97.1% 92.1%
3264561 3883.1.1.1 ↗ alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.69 62.0 4.71e-01 99.0% 48.6%
4950911 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 46.0 4.15e-01 86.5% 49.0%
4646569 4994.1.1.1 ↗ alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.68 48.0 5.03e-01 82.7% 80.0%
3510367 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.68 58.0 5.06e-01 92.3% 99.4%
3373370 603.2.1.15 ↗ alpha bundles › STAT-like › STAT › STAT › DUF6857 0.68 58.0 4.51e-01 92.3% 71.6%
3733626 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 54.0 4.95e-01 86.5% 70.7%
3317397 603.1.1.17 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.67 61.0 4.83e-01 98.1% 85.9%
2035519 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.67 54.0 5.16e-01 85.6% 76.5%
5076670 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.67 53.0 4.91e-01 89.4% 65.9%
4277373 4994.1.1.1 ↗ alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.66 47.0 4.91e-01 82.7% 81.7%
4010267 192.8.1.131 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › GNVR 0.65 45.0 4.22e-01 74.0% 57.7%
3815122 604.12.1.68 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 0.65 59.0 4.86e-01 99.0% 57.8%
3907206 603.1.1.124 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE, V-SNARE_C 0.64 60.0 4.92e-01 100.0% 75.0%
5083098 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 49.0 5.05e-01 85.6% 85.0%
3714029 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 57.0 4.64e-01 100.0% 95.8%
3401221 109.4.1.63 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAP42 0.62 56.0 4.33e-01 100.0% 47.4%
3173260 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 56.0 4.52e-01 100.0% 61.0%
3462175 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 53.0 4.95e-01 96.2% 83.8%
3913986 192.1.1.36 ↗ alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › BAG6 0.57 42.0 4.24e-01 77.9% 84.8%
4243427 3560.1.1.1 ↗ a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 0.57 47.0 4.04e-01 93.3% 57.5%
3236340 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 47.0 4.01e-01 91.3% 78.2%
4565268 3560.1.1.1 ↗ a+b complex topology › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Mediator of RNA polymerase II transcription subunit 8 › Med8 0.56 47.0 3.79e-01 92.3% 48.4%
3930934 5054.1.1.8 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.56 50.0 3.64e-01 97.1% 89.3%
3579019 5001.1.1.31 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › GPR180-TMEM145_TM 0.56 50.0 4.15e-01 98.1% 71.7%
3763555 109.4.1.1505 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_FBXO47 0.56 44.0 3.55e-01 85.6% 80.0%
D5 medium residues 448-550
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_009230153__Leporid_alphaherpesvirus_4__481315__D456-564
D6 medium residues 551-653
PDB
Domain cluster: rep: envelope_glycoprotein_H__NP_045337__Bovine_alphaherpesvirus_1__10320__D538-631