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envelope_glycoprotein_H

Euk-Vir

Suid_alphaherpesvirus_1

envelope_glycoprotein_H__YP_068353__Suid_alphaherpesvirus_1__10345

Identity

Accession:
YP_068353 ↗
Protein ID:
envelope_glycoprotein_H
Kingdom:
euk

Quality

74.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Suid_alphaherpesvirus_1

TaxID: 10345

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 340-467
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 22.8 4.60e-05 75.0% 10.6%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA02 1.20.58.1340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.96 91.0 8.71e-01 100.0% 87.4%
4gtnA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.68 39.0 4.87e-01 89.8% 95.9%
7k0yA01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.61 53.0 3.61e-01 96.1% 29.8%
3ltjA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 44.0 3.85e-01 93.8% 51.3%
2elcA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.60 32.0 4.08e-01 89.1% 95.5%
3wozB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 45.0 3.69e-01 84.4% 52.4%
4l7mA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.56 48.0 3.82e-01 96.9% 46.0%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.53 45.0 3.80e-01 93.8% 77.3%
4g3aB00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.52 43.0 3.51e-01 89.1% 49.1%
1hqoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 36.0 3.64e-01 74.2% 88.5%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
119302 3146.1.1.0 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain 0.96 91.0 6.41e-01 100.0% 37.7%
2095476 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.83 78.0 4.92e-01 98.4% 28.8%
3435822 109.4.1.1257 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.73 41.0 3.64e-01 87.5% 39.4%
3804192 109.4.1.1256 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.70 40.0 3.60e-01 92.2% 39.9%
3424689 109.4.1.1257 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.69 41.0 3.73e-01 92.2% 43.5%
3802665 109.4.1.883 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 0.61 47.0 4.93e-01 88.3% 88.7%
3595808 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 3.28e-01 98.4% 20.5%
3613340 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 44.0 2.97e-01 89.1% 21.3%
3459018 109.4.1.420 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.59 43.0 3.93e-01 82.0% 58.8%
60072 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 35.0 4.23e-01 82.0% 95.3%
3419204 109.4.1.1282 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, TPR_24 0.56 43.0 3.03e-01 91.4% 25.7%
3832025 109.4.1.189 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.55 41.0 4.00e-01 90.6% 69.0%
3895354 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 46.0 4.54e-01 89.8% 86.7%
3645713 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 41.0 4.07e-01 90.6% 73.6%
4003670 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 45.0 4.04e-01 90.6% 67.0%
3348706 109.4.1.394 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RMC1_C 0.54 41.0 3.64e-01 93.0% 55.1%
3776919 109.4.1.1749 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_ECM29 0.54 48.0 4.06e-01 100.0% 75.0%
3734329 109.4.1.58 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Not1 0.53 44.0 3.09e-01 91.4% 36.7%
3307130 109.4.1.1256 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3 0.52 40.0 3.69e-01 95.3% 63.0%
3269180 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 40.0 4.27e-01 88.3% 96.4%
3195345 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 42.0 3.94e-01 90.6% 93.1%
D2 high residues 499-636
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 52.6 5.60e-14 99.3% 90.8%
D3 medium residues 55-73_124-239
PDB
Domain cluster: rep: envelope_glycoprotein_H__YP_010087581__Cervid_alphaherpesvirus_3__2115790__D207-328
D4 medium residues 240-339
PDB
Domain cluster: representative
CATH (70)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xqyA01 3.30.500.50 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › 0.95 85.0 6.71e-01 92.0% 51.7%
2gomA00 1.10.10.1270 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Sbi, C3 binding domain IV 0.93 52.0 6.76e-01 75.0% 93.4%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.88 65.0 5.67e-01 77.0% 58.7%
3rkgA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.81 59.0 4.89e-01 75.0% 68.9%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.80 45.0 5.75e-01 70.0% 96.6%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.80 58.0 5.51e-01 75.0% 64.7%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 58.0 5.80e-01 76.0% 90.3%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 57.0 5.65e-01 76.0% 91.4%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.78 55.0 6.19e-01 76.0% 94.8%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.78 56.0 5.58e-01 74.0% 87.3%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 56.0 5.10e-01 76.0% 80.0%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.77 58.0 5.50e-01 80.0% 83.9%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 56.0 4.61e-01 76.0% 72.8%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 54.0 6.08e-01 76.0% 97.3%
1w99A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.75 68.0 5.69e-01 100.0% 86.7%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.75 55.0 5.37e-01 76.0% 74.1%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.75 55.0 5.09e-01 76.0% 71.0%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.74 68.0 5.13e-01 100.0% 65.5%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.74 53.0 5.35e-01 75.0% 89.2%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.74 54.0 4.43e-01 77.0% 53.3%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.74 53.0 5.06e-01 75.0% 73.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.73 51.0 4.82e-01 71.0% 86.3%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.73 47.0 5.13e-01 77.0% 78.3%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.73 53.0 4.40e-01 76.0% 54.5%
4ozvA00 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.73 67.0 4.60e-01 100.0% 46.5%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 53.0 5.49e-01 76.0% 91.4%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.72 51.0 5.62e-01 74.0% 92.4%
4ecgA00 1.20.1420.20 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif 0.72 57.0 3.78e-01 83.0% 63.3%
3bvoA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.72 50.0 5.34e-01 72.0% 87.2%
8bykA01 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.71 65.0 4.19e-01 100.0% 29.6%
2xl4A00 1.20.120.1420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › LntA helical domain 0.70 63.0 5.53e-01 98.0% 81.0%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 50.0 5.04e-01 75.0% 89.2%
7powA01 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.70 57.0 4.55e-01 88.0% 50.0%
7xrxB01 1.20.1420.20 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › M75 peptidase, HXXE motif 0.70 56.0 3.70e-01 85.0% 65.3%
3zc0D00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 63.0 5.09e-01 100.0% 77.5%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.69 50.0 4.23e-01 76.0% 52.7%
3t5vA00 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.69 63.0 4.44e-01 100.0% 36.1%
1orjD00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.69 48.0 4.51e-01 73.0% 62.4%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 61.0 4.95e-01 99.0% 78.0%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.68 50.0 4.11e-01 79.0% 54.5%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 49.0 4.64e-01 76.0% 90.8%
1ug7A00 1.20.120.360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain 0.68 55.0 5.10e-01 89.0% 92.2%
2qwtA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.67 52.0 4.41e-01 83.0% 80.8%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 61.0 4.91e-01 100.0% 84.9%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.67 49.0 4.69e-01 77.0% 66.7%
6u3wB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.67 54.0 3.88e-01 100.0% 29.9%
4ackB00 1.25.40.590 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU 0.67 59.0 5.16e-01 99.0% 93.5%
2jx0A00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.67 50.0 4.56e-01 79.0% 71.8%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.66 48.0 4.47e-01 76.0% 68.3%
6vudA01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 47.0 4.59e-01 75.0% 93.6%
5lx8A00 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 57.0 3.65e-01 100.0% 57.3%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.65 48.0 4.71e-01 77.0% 76.6%
4agsB04 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 57.0 5.25e-01 100.0% 82.7%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.64 56.0 5.30e-01 94.0% 93.3%
2yfaB01 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.64 57.0 5.41e-01 97.0% 88.2%
1yw0A00 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 51.0 3.89e-01 89.0% 79.0%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 55.0 4.02e-01 97.0% 93.0%
3wd6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.62 55.0 5.22e-01 99.0% 91.5%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.62 46.0 3.66e-01 79.0% 72.0%
2d2sA02 1.20.58.1220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain 0.61 50.0 5.00e-01 89.0% 94.1%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.60 54.0 3.70e-01 99.0% 89.0%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.60 49.0 4.65e-01 87.0% 86.6%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.60 51.0 4.85e-01 96.0% 77.1%
1zoyD00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.60 45.0 4.48e-01 78.0% 92.2%
2w02B01 1.10.150.640 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle 0.60 32.0 3.69e-01 78.0% 70.3%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.59 40.0 4.45e-01 70.0% 89.7%
2i9cA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.59 46.0 4.53e-01 100.0% 76.6%
4m7cB00 1.25.40.210 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain 0.56 50.0 4.00e-01 100.0% 55.6%
2y1vA04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 49.0 4.01e-01 100.0% 54.1%
6a3kA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.52 45.0 4.20e-01 97.0% 89.1%
ECOD (73)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
119302 3146.1.1.0 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain 0.94 91.0 6.01e-01 100.0% 30.1%
3612915 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.85 60.0 5.93e-01 73.0% 92.4%
4524825 604.9.1.1 ↗ alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.83 58.0 6.00e-01 72.0% 76.8%
2324029 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.83 61.0 5.70e-01 77.0% 68.0%
3576710 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.81 58.0 6.23e-01 76.0% 87.1%
1713219 601.4.1.5 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › HBM 0.80 59.0 5.64e-01 76.0% 69.9%
4981185 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.80 58.0 4.74e-01 75.0% 95.4%
3786136 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.79 57.0 5.47e-01 76.0% 76.5%
3253634 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.78 57.0 5.60e-01 76.0% 71.4%
3611527 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.78 67.0 5.97e-01 91.0% 85.2%
3241687 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 56.0 5.37e-01 76.0% 82.6%
3925326 601.11.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain 0.77 58.0 4.82e-01 79.0% 52.4%
4857065 633.1.1.0 ↗ alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.77 53.0 5.11e-01 73.0% 63.4%
3810544 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.77 56.0 5.10e-01 77.0% 83.7%
3684923 109.4.1.681 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.76 69.0 4.48e-01 100.0% 26.6%
3927006 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.76 55.0 5.78e-01 76.0% 97.8%
3185438 603.1.1.97 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.76 62.0 4.89e-01 88.0% 92.5%
4270503 604.9.1.1 ↗ alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.75 48.0 5.22e-01 71.0% 77.6%
4023003 109.4.1.681 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 0.75 67.0 4.36e-01 99.0% 78.1%
3307044 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 54.0 5.37e-01 76.0% 81.0%
3398644 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 59.0 5.22e-01 100.0% 58.6%
3992590 603.1.1.110 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF26585 0.74 53.0 5.38e-01 75.0% 93.0%
3760737 601.16.1.17 ↗ alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › PF27561 0.73 53.0 4.77e-01 76.0% 61.4%
3722749 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 67.0 5.07e-01 99.0% 54.7%
3444505 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 59.0 4.59e-01 87.0% 54.0%
3862607 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.73 54.0 5.06e-01 77.0% 68.3%
3611803 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.73 66.0 4.90e-01 100.0% 85.2%
5047254 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 66.0 5.03e-01 100.0% 50.2%
4993965 5069.1.1.15 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.72 55.0 4.79e-01 80.0% 65.3%
3282614 109.3.1.381 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF2339 0.72 66.0 5.03e-01 99.0% 63.2%
3500905 604.13.1.1 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer 0.72 52.0 4.85e-01 76.0% 66.4%
3624929 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 64.0 6.00e-01 100.0% 91.2%
5079204 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.72 65.0 5.23e-01 100.0% 77.4%
3723343 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.72 64.0 4.10e-01 100.0% 31.9%
4944331 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.71 63.0 5.20e-01 99.0% 83.3%
1030741 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.71 65.0 5.65e-01 97.0% 71.0%
3669425 109.4.1.541 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 0.70 64.0 4.74e-01 100.0% 91.2%
4927814 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.70 63.0 4.94e-01 100.0% 71.2%
4947089 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.70 63.0 5.04e-01 100.0% 75.4%
3510367 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.69 57.0 4.89e-01 88.0% 98.1%
4222712 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 57.0 4.59e-01 89.0% 52.1%
3445955 109.4.1.541 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 0.69 61.0 4.54e-01 100.0% 78.9%
3715189 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.69 63.0 4.31e-01 97.0% 39.4%
5055683 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.69 61.0 5.14e-01 99.0% 85.9%
3562533 109.4.1.192 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.68 57.0 4.63e-01 92.0% 47.9%
5084074 109.10.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.68 61.0 4.77e-01 100.0% 71.6%
3579611 3883.1.1.1 ↗ alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.68 60.0 4.82e-01 98.0% 60.0%
3719031 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 56.0 4.47e-01 89.0% 66.7%
4948915 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.68 62.0 4.79e-01 98.0% 89.5%
150489 601.1.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › CHASE3 0.68 64.0 5.83e-01 100.0% 81.1%
5054675 3883.1.1.1 ↗ alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.68 56.0 4.75e-01 90.0% 63.0%
3594445 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.67 62.0 5.69e-01 98.0% 83.2%
4997415 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.67 60.0 5.35e-01 98.0% 79.3%
3690080 603.5.1.0 ↗ alpha bundles › STAT-like › FlgN-like › FlgN-like 0.67 55.0 5.23e-01 90.0% 95.8%
3710914 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 54.0 3.23e-01 89.0% 15.8%
4646569 4994.1.1.1 ↗ alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.66 47.0 4.84e-01 74.0% 84.2%
3304520 109.4.1.1308 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_3, TPR_24 0.66 60.0 3.75e-01 100.0% 20.6%
4277373 4994.1.1.1 ↗ alpha duplicates or obligate multimers › EF2458-like › EF2458-like › EF2458-like › DUF1507 0.65 46.0 4.81e-01 74.0% 86.0%
3973510 601.4.1.5 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › HBM 0.65 56.0 5.12e-01 93.0% 80.8%
3975942 601.4.1.6 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.65 58.0 5.27e-01 97.0% 77.7%
3701224 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.64 48.0 4.48e-01 79.0% 80.8%
3230694 1065.1.1.5 ↗ alpha bundles › SPX domain › SPX domain › SPX domain › DUF19 0.64 59.0 5.09e-01 100.0% 98.7%
5052922 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.64 57.0 5.37e-01 97.0% 91.7%
4647884 601.2.1.7 ↗ alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › HBM 0.64 57.0 5.15e-01 97.0% 93.3%
2492495 601.33.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.63 54.0 4.69e-01 94.0% 63.2%
3714029 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 55.0 4.46e-01 97.0% 93.2%
4011562 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.62 55.0 3.62e-01 100.0% 23.6%
3388850 109.4.1.228 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C 0.60 52.0 3.68e-01 100.0% 36.1%
3558994 109.4.1.395 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fanconi_C 0.58 50.0 3.25e-01 100.0% 20.7%
5063259 601.33.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.58 51.0 4.76e-01 97.0% 92.0%
4935668 601.33.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD 0.57 52.0 4.71e-01 97.0% 93.1%
4202300 601.1.1.131 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF373 0.57 47.0 4.46e-01 90.0% 96.7%
4944372 5073.1.2.0 ↗ alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.50 43.0 3.29e-01 100.0% 93.3%