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envelope_glycoprotein_H

Euk-Vir

Human_betaherpesvirus_7

envelope_glycoprotein_H__YP_073788__Human_betaherpesvirus_7__10372

Identity

Accession:: YP_073788 ↗
Protein ID:: envelope_glycoprotein_H
Kingdom:: euk

Quality

81.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_7

TaxID: 10372

Cluster

View cluster (43 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 111-145_255-359

PDB

Domain cluster: rep: envelope_glycoprotein_H__YP_009253953__Macaca_nemestrina_herpesvirus_7__1846169__D249-354

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	32.7	4.90e-08	91.4%	17.8%

D2 medium residues 146-254

PDB

Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	36.4	3.50e-09	95.4%	14.2%

D3 medium residues 360-474

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02489.22 best	Herpes_glycop_H	59.8	2.90e-16	100.0%	23.4%

CATH (19)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1t98A02	1.20.58.590	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain	0.69	51.0	4.60e-01	79.1%	92.0%
6a2aA01	1.50.10.130	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain	0.68	55.0	4.58e-01	100.0%	50.5%
1gw5A00	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.64	58.0	3.68e-01	100.0%	26.4%
4epzA00	1.25.40.810	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ	0.63	53.0	4.85e-01	96.5%	68.8%
5cwhA01	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.61	56.0	5.03e-01	100.0%	77.6%
3cf6E05	1.10.840.10	Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain	0.58	47.0	3.79e-01	89.6%	71.0%
3zheC01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.57	45.0	3.87e-01	97.4%	53.3%
8amzP01	1.25.40.570	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.56	50.0	3.53e-01	100.0%	33.6%
6f7hA00	1.20.1080.10	Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein.	0.56	45.0	3.60e-01	88.7%	83.3%
4y6cA00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.56	50.0	4.10e-01	100.0%	64.2%
3c02A00	1.20.1080.10	Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein.	0.56	45.0	3.61e-01	88.7%	83.1%
1bwoA00	1.10.110.10	Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins	0.54	39.0	4.32e-01	96.5%	97.8%
1dk8A02	1.10.167.10	Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2	0.54	33.0	3.69e-01	73.9%	80.0%
3l09A01	1.20.58.1460	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	39.0	4.21e-01	76.5%	98.0%
5an3A01	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.53	44.0	4.30e-01	100.0%	82.2%
3cllA00	1.20.1080.10	Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein.	0.53	43.0	3.48e-01	89.6%	78.8%
1zu2A00	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.53	46.0	4.21e-01	100.0%	75.9%
2vvwA00	1.10.437.20	Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › dsDNA poxvirus	0.53	40.0	3.70e-01	86.1%	62.0%
2b1eA02	1.20.1310.30	Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like ›	0.50	43.0	3.99e-01	96.5%	94.7%

ECOD (17)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2095503	3146.1.1.1 ↗	a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H	0.88	84.0	5.27e-01	100.0%	65.9%
3921091	603.1.1.103 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732	0.70	57.0	5.28e-01	87.0%	91.0%
4187493	603.1.1.103 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF29732	0.68	56.0	5.17e-01	87.8%	89.7%
3539086	109.25.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A	0.66	56.0	5.66e-01	96.5%	93.0%
3847817	109.25.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN	0.66	56.0	5.66e-01	96.5%	93.0%
1146575	109.39.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › transcription anti-terminator antagonist UpxZ › transcription anti-terminator antagonist UpxZ › UpxZ	0.63	53.0	4.85e-01	96.5%	68.8%
3976607	604.34.1.1 ↗	alpha bundles › Spectrin repeat-like › Helical bundle domain in arginine decarboxylase › Helical bundle domain in arginine decarboxylase › Arg_decarb_HB	0.62	45.0	4.77e-01	74.8%	88.0%
3686313	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.62	56.0	4.29e-01	100.0%	95.1%
3560386	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.62	57.0	4.62e-01	100.0%	61.9%
3930124	109.25.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN	0.61	53.0	5.14e-01	96.5%	84.6%
5059963	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.61	52.0	4.90e-01	96.5%	89.7%
3858384	220.1.1.311 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › RasGEF	0.60	49.0	3.41e-01	89.6%	43.5%
3505828	109.4.1.95 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2	0.59	46.0	4.03e-01	92.2%	55.3%
3621072	109.4.1.443 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MOR2-PAG1_C	0.56	46.0	4.01e-01	100.0%	56.8%
5057127	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.55	50.0	3.85e-01	100.0%	55.7%
3817383	109.4.1.401 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › NRDE-2	0.54	42.0	4.20e-01	99.1%	81.7%
3583634	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.53	46.0	3.90e-01	98.3%	86.3%

D4 medium residues 584-659

PDB

Domain cluster: rep: envelope_glycoprotein_H__YP_004936041__Cercopithecine_betaherpesvirus_5__50292__D611-687

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF17488.8 best	Herpes_glycoH_C	66.2	3.50e-18	96.0%	50.3%