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envelope_glycoprotein_L
Euk-VirPapiine_alphaherpesvirus_2
envelope_glycoprotein_L__YP_443847__Papiine_alphaherpesvirus_2__340907
Identity
- Accession:
- YP_443847 ↗
- Protein ID:
- envelope_glycoprotein_L
- Kingdom:
- euk
Quality
61.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Papiine_alphaherpesvirus_2
TaxID: 340907
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 34-58_75-103
Domain cluster:
rep: envelope_glycoprotein_L__NP_077474__Cercopithecine_alphaherpesvirus_9__35246__D24-97
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05259.17 best | Herpes_UL1 | 42.7 | 7.30e-11 | 61.1% | 27.1% |
CATH (22)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3m1cB01 | 3.30.390.170 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.94 | 88.0 | 6.78e-01 | 100.0% | 64.2% |
| 4wj7D00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.70 | 59.0 | 4.60e-01 | 96.3% | 79.7% |
| 1itxA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.60 | 51.0 | 4.66e-01 | 96.3% | 98.6% |
| 4yy8A02 | 2.120.10.80 | Mainly Beta › 6 Propeller › Neuraminidase › Kelch-type beta propeller | 0.60 | 45.0 | 2.81e-01 | 81.5% | 24.8% |
| 5dezA03 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.57 | 48.0 | 4.34e-01 | 94.4% | 93.2% |
| 2mdiA00 | 2.20.70.10 | Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; › | 0.57 | 41.0 | 4.10e-01 | 83.3% | 75.0% |
| 2j3lA01 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.56 | 37.0 | 2.95e-01 | 79.6% | 32.7% |
| 3rm5B01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.55 | 39.0 | 2.45e-01 | 88.9% | 13.9% |
| 4fchA02 | 2.60.40.3610 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 39.0 | 3.28e-01 | 81.5% | 100.0% |
| 1mpgA01 | 3.30.310.20 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain | 0.53 | 44.0 | 3.54e-01 | 94.4% | 55.4% |
| 1g5hB02 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.53 | 38.0 | 3.11e-01 | 79.6% | 40.2% |
| 1lkfA00 | 2.70.240.10 | Mainly Beta › Distorted Sandwich › Leukocidin-like › Leukocidin/porin MspA | 0.53 | 42.0 | 2.80e-01 | 100.0% | 67.5% |
| 3pr6A00 | 3.30.450.70 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.53 | 43.0 | 3.28e-01 | 96.3% | 51.7% |
| 4mboA01 | 2.60.40.1280 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 46.0 | 3.35e-01 | 100.0% | 62.9% |
| 1w96C04 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.52 | 45.0 | 2.91e-01 | 100.0% | 75.4% |
| 1khiA01 | 2.30.30.30 | Mainly Beta › Roll › SH3 type barrels. › | 0.52 | 41.0 | 3.83e-01 | 96.3% | 97.3% |
| 2gq1A01 | 3.30.540.10 | Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1 | 0.51 | 42.0 | 2.99e-01 | 92.6% | 98.2% |
| 2xlpB01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.51 | 39.0 | 2.50e-01 | 94.4% | 46.4% |
| 1w9pA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.51 | 41.0 | 4.00e-01 | 96.3% | 98.4% |
| 3zfnA02 | 2.30.140.40 | Mainly Beta › Roll › Spermidine Synthase; Chain: A, domain 2 › Pestivirus Npro endopeptidase C53, interaction domain | 0.51 | 41.0 | 4.05e-01 | 94.4% | 86.0% |
| 8ouzD01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 34.0 | 2.30e-01 | 72.2% | 17.9% |
| 1twfI02 | 2.20.25.10 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › | 0.50 | 40.0 | 3.60e-01 | 88.9% | 76.3% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2095477 | 1170.1.2.2 ↗ | beta barrels › IL8-related › IL8-related › chemokine-related domain in glycoprotein L (gL) | 0.94 | 88.0 | 6.30e-01 | 100.0% | 50.4% |
| 1556781 | 3146.1.1.2 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_UL1 | 0.86 | 77.0 | 5.68e-01 | 98.1% | 51.5% |
| 4937515 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.62 | 41.0 | 3.41e-01 | 90.7% | 41.1% |
| 3807987 | 5.1.3.6 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 | 0.61 | 46.0 | 2.83e-01 | 81.5% | 21.7% |
| 210920 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.61 | 51.0 | 4.42e-01 | 96.3% | 98.9% |
| 3741358 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.61 | 46.0 | 2.95e-01 | 83.3% | 18.7% |
| 4202852 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.60 | 42.0 | 3.30e-01 | 90.7% | 37.1% |
| 3986256 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.59 | 36.0 | 3.54e-01 | 90.7% | 55.0% |
| 3985807 | 375.1.1.130 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Zn_Tnp_IS1 | 0.59 | 36.0 | 3.88e-01 | 90.7% | 73.3% |
| 6500 | 284.2.1.1 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain › Glyco_hydro_18 | 0.58 | 49.0 | 4.47e-01 | 96.3% | 98.6% |
| 3842985 | 11.1.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Cadherin | 0.57 | 47.0 | 3.27e-01 | 100.0% | 69.5% |
| 3992062 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.55 | 41.0 | 2.66e-01 | 81.5% | 19.2% |
| 3538405 | 11.12.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD | 0.54 | 40.0 | 2.75e-01 | 83.3% | 80.5% |
| 3935617 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.54 | 44.0 | 2.76e-01 | 96.3% | 87.6% |
| 223688 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.53 | 38.0 | 4.09e-01 | 88.9% | 91.1% |
| 1294200 | 11.12.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like › Neur_chan_LBD | 0.53 | 38.0 | 2.70e-01 | 83.3% | 80.2% |
| 3403199 | 331.1.1.1 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › TBP | 0.53 | 45.0 | 3.59e-01 | 96.3% | 50.9% |
| 3639522 | 2003.1.2.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 | 0.53 | 40.0 | 2.64e-01 | 88.9% | 54.0% |
| 3480351 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.52 | 35.0 | 3.23e-01 | 100.0% | 52.0% |
| None | — | 0.51 | 43.0 | 2.57e-01 | 100.0% | 13.7% | |
| 4078775 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.51 | 42.0 | 3.82e-01 | 94.4% | 74.7% |
| 3907113 | 220.1.1.66 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › SOS1_NGEF_PH | 0.50 | 42.0 | 3.10e-01 | 96.3% | 57.4% |
| 3973387 | 5.1.5.74 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF3686 | 0.50 | 43.0 | 2.69e-01 | 98.1% | 82.3% |
| 4013690 | 284.2.1.0 ↗ | a+b two layers › FKBP-like › Chitinase insertion domain › Chitinase insertion domain | 0.50 | 40.0 | 3.98e-01 | 96.3% | 87.3% |
D2
medium
residues 59-74_104-155
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05259.17 best | Herpes_UL1 | 22.3 | 1.60e-04 | 61.8% | 29.0% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1u5eA01 | 6.10.250.220 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.81 | 55.0 | 6.14e-01 | 70.6% | 92.5% |
| 6f1eA01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.79 | 54.0 | 4.19e-01 | 70.6% | 46.0% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.79 | 58.0 | 4.98e-01 | 76.5% | 55.9% |
| 3m1cB01 | 3.30.390.170 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.77 | 61.0 | 5.14e-01 | 83.8% | 77.1% |
| 2gv9A05 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.74 | 57.0 | 6.13e-01 | 89.7% | 94.9% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.70 | 57.0 | 4.75e-01 | 91.2% | 51.3% |
| 3fxdB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 51.0 | 5.48e-01 | 77.9% | 100.0% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 51.0 | 5.28e-01 | 92.6% | 85.9% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.64 | 58.0 | 3.66e-01 | 100.0% | 21.4% |
| 3fb2A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 54.0 | 4.67e-01 | 100.0% | 73.3% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.56 | 41.0 | 3.99e-01 | 94.1% | 70.9% |
| 2q83A02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.53 | 44.0 | 3.12e-01 | 97.1% | 28.3% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3832236 | 650.1.1.0 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain | 0.77 | 53.0 | 5.33e-01 | 75.0% | 70.0% |
| 3807618 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.77 | 56.0 | 6.14e-01 | 85.3% | 92.7% |
| 1821875 | 4970.1.1.1 ↗ | alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B | 0.74 | 57.0 | 6.05e-01 | 88.2% | 93.2% |
| 4943086 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.73 | 56.0 | 5.58e-01 | 80.9% | 82.9% |
| 3876167 | 220.1.1.1 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH | 0.69 | 58.0 | 4.22e-01 | 91.2% | 80.0% |
| 3744805 | 375.10.1.1 ↗ | few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha › zf-DNA_Pol | 0.63 | 50.0 | 4.69e-01 | 86.8% | 72.9% |