←Back to structures
envelope_glycoprotein_M
Euk-VirElephant_endotheliotropic_herpesvirus_5
envelope_glycoprotein_M__YP_009051979__Elephant_endotheliotropic_herpesvirus_5__768738
Identity
- Accession:
- YP_009051979 ↗
- Protein ID:
- envelope_glycoprotein_M
- Kingdom:
- euk
Quality
82.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Proboscivirus›
Elephant_endotheliotropic_herpesvirus_5
TaxID: 768738
Cluster
View cluster (76 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-53_67-250
Domain cluster:
rep: envelope_glycoprotein_M__YP_009176930__Testudinid_alphaherpesvirus_3__2560801__D21-51_67-230
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 192.2 | 2.00e-56 | 99.1% | 73.7% |
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.80 | 44.0 | 5.56e-01 | 70.0% | 85.7% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.78 | 42.0 | 5.22e-01 | 70.8% | 82.4% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.76 | 55.0 | 4.79e-01 | 72.5% | 85.2% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.74 | 54.0 | 4.87e-01 | 73.0% | 83.5% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.73 | 32.0 | 4.21e-01 | 79.4% | 71.4% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.73 | 46.0 | 5.45e-01 | 75.5% | 88.5% |
| 2fefA01 | 1.20.1440.70 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › PA2201 N-terminal domain-like | 0.72 | 40.0 | 5.36e-01 | 72.1% | 100.0% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.72 | 45.0 | 4.63e-01 | 74.7% | 63.8% |
| 7qx4A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.70 | 43.0 | 4.36e-01 | 75.5% | 59.8% |
| 1ciyA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.70 | 44.0 | 4.60e-01 | 75.1% | 66.5% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.67 | 43.0 | 4.91e-01 | 76.8% | 82.6% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 43.0 | 5.15e-01 | 70.8% | 98.1% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 40.0 | 4.96e-01 | 85.8% | 99.3% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 43.0 | 5.15e-01 | 75.1% | 100.0% |
| 3mvuA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.65 | 45.0 | 4.57e-01 | 91.4% | 71.9% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 42.0 | 5.05e-01 | 70.8% | 98.7% |
| 4p3fA00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.63 | 39.0 | 4.33e-01 | 92.3% | 74.6% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.62 | 42.0 | 4.91e-01 | 78.1% | 100.0% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.62 | 41.0 | 4.56e-01 | 84.1% | 82.3% |
| 1lb3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 40.0 | 4.65e-01 | 94.0% | 89.8% |
| 1at9A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.60 | 41.0 | 4.15e-01 | 84.1% | 68.3% |
| 2dfkC01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.60 | 46.0 | 4.83e-01 | 79.8% | 86.8% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 30.0 | 3.62e-01 | 73.8% | 70.2% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 38.0 | 3.97e-01 | 95.3% | 68.5% |
| 2epkX03 | 1.20.120.670 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › N-acetyl-b-d-glucoasminidase | 0.58 | 43.0 | 4.40e-01 | 94.4% | 78.1% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.56 | 38.0 | 4.36e-01 | 71.2% | 89.8% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 4.80e-01 | 88.0% | 99.0% |
| 1zb1A00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.55 | 50.0 | 4.19e-01 | 100.0% | 59.4% |
| 1st6A02 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.54 | 37.0 | 3.75e-01 | 93.6% | 67.4% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 29.0 | 3.57e-01 | 71.2% | 78.6% |
| 2incB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.54 | 45.0 | 4.03e-01 | 88.0% | 93.2% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.53 | 35.0 | 4.14e-01 | 83.3% | 94.5% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 41.0 | 4.43e-01 | 93.1% | 94.0% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 38.0 | 4.31e-01 | 94.4% | 96.1% |
| 7zdtD01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.52 | 39.0 | 3.50e-01 | 76.4% | 95.1% |
| 2xs1A01 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.51 | 48.0 | 4.15e-01 | 100.0% | 68.1% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 41.0 | 3.99e-01 | 92.7% | 77.3% |
ECOD (42)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3920855 | 3861.1.1.3 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › PF30661 | 0.90 | 79.0 | 7.36e-01 | 98.3% | 76.0% |
| 5002523 | 3861.1.1.3 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › PF30661 | 0.86 | 62.0 | 7.25e-01 | 87.1% | 100.0% |
| 3994022 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.79 | 48.0 | 6.14e-01 | 77.3% | 100.0% |
| 3866648 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.77 | 52.0 | 6.23e-01 | 70.0% | 98.8% |
| 3494045 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 49.0 | 6.00e-01 | 74.7% | 99.3% |
| 3625011 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 50.0 | 6.07e-01 | 71.7% | 100.0% |
| 3525698 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.75 | 44.0 | 5.73e-01 | 71.7% | 100.0% |
| 3998921 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.75 | 48.0 | 5.92e-01 | 77.3% | 100.0% |
| 3784672 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.75 | 49.0 | 5.62e-01 | 75.1% | 88.8% |
| 3548233 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.74 | 52.0 | 6.15e-01 | 73.0% | 100.0% |
| 3873670 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.74 | 53.0 | 6.15e-01 | 88.4% | 100.0% |
| 3762118 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.74 | 51.0 | 6.05e-01 | 70.4% | 98.8% |
| 3428102 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.72 | 43.0 | 4.92e-01 | 70.0% | 77.7% |
| 5043625 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.72 | 45.0 | 5.54e-01 | 87.1% | 96.7% |
| 4506674 | 5000.4.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N | 0.70 | 44.0 | 4.33e-01 | 75.1% | 57.6% |
| 3995562 | 602.2.1.0 ↗ | alpha arrays › L-aspartase middle domain-like › RNA-binding protein She2p › RNA-binding protein She2p | 0.69 | 50.0 | 4.95e-01 | 73.0% | 94.3% |
| 3305831 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.69 | 46.0 | 5.47e-01 | 72.5% | 98.7% |
| 3214913 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 47.0 | 5.49e-01 | 72.5% | 97.1% |
| 3629651 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 45.0 | 5.34e-01 | 71.7% | 100.0% |
| 3509307 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.66 | 46.0 | 5.28e-01 | 72.1% | 94.3% |
| 5026949 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.66 | 51.0 | 5.31e-01 | 88.0% | 87.0% |
| 5062169 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.65 | 49.0 | 5.15e-01 | 87.1% | 87.3% |
| 3408341 | 174.1.1.29 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4728 | 0.64 | 45.0 | 5.20e-01 | 70.8% | 100.0% |
| 3933140 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.64 | 45.0 | 5.02e-01 | 71.2% | 90.8% |
| 3246911 | 601.1.2.49 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PPP1R21_helical | 0.62 | 42.0 | 4.41e-01 | 80.7% | 72.6% |
| 3263275 | 133.1.1.0 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) | 0.62 | 49.0 | 4.84e-01 | 80.7% | 77.1% |
| 3496300 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.62 | 42.0 | 4.95e-01 | 74.7% | 98.1% |
| 4948739 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.62 | 48.0 | 5.00e-01 | 98.3% | 88.5% |
| 4101139 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.62 | 49.0 | 5.08e-01 | 86.3% | 87.3% |
| 4951914 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.62 | 46.0 | 4.89e-01 | 90.6% | 87.3% |
| 4968767 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.61 | 46.0 | 4.83e-01 | 90.1% | 87.3% |
| 3773055 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.61 | 38.0 | 4.63e-01 | 75.5% | 97.9% |
| 3613755 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.60 | 50.0 | 5.02e-01 | 89.7% | 87.7% |
| 3930016 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.55 | 41.0 | 3.88e-01 | 77.7% | 64.8% |
| 3260820 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.54 | 44.0 | 4.14e-01 | 91.4% | 70.5% |
| 3592430 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.52 | 41.0 | 3.47e-01 | 81.5% | 81.3% |
| 3464386 | 604.5.1.42 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › Mlo | 0.52 | 38.0 | 4.01e-01 | 79.4% | 83.3% |
| 3938965 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.51 | 40.0 | 3.99e-01 | 81.1% | 80.0% |
| 5039743 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.51 | 31.0 | 3.64e-01 | 73.0% | 84.2% |
| 4002015 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.51 | 42.0 | 4.28e-01 | 99.1% | 88.9% |
| 4261817 | 5086.1.1.91 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › PRM1 | 0.51 | 38.0 | 4.09e-01 | 86.7% | 90.7% |
| 3993135 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 41.0 | 4.41e-01 | 95.3% | 99.5% |
D2
medium
residues 251-327
Domain cluster:
rep: envelope_glycoprotein_M__YP_009176930__Testudinid_alphaherpesvirus_3__2560801__D231-337
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 79.4 | 3.90e-22 | 100.0% | 23.3% |