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envelope_glycoprotein_M

Euk-Vir

Equid_alphaherpesvirus_3

envelope_glycoprotein_M__YP_009054955__Equid_alphaherpesvirus_3__80341

Identity

Accession:
YP_009054955 ↗
Protein ID:
envelope_glycoprotein_M
Kingdom:
euk

Quality

74.8 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 30-60_87-130
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01528.23 best Herpes_glycop 28.5 1.20e-06 58.7% 11.9%
PF01528.23 Herpes_glycop 27.4 2.60e-06 44.0% 9.2%
CATH (70)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 63.0 6.24e-01 100.0% 79.2%
7zd5C01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.79 68.0 4.36e-01 100.0% 21.8%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.79 68.0 4.62e-01 100.0% 28.5%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.78 59.0 5.55e-01 97.3% 65.9%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 59.0 6.16e-01 100.0% 91.0%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 63.0 5.55e-01 100.0% 61.9%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.77 47.0 4.93e-01 100.0% 68.7%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 56.0 5.09e-01 100.0% 58.6%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.76 62.0 5.85e-01 100.0% 73.3%
4lwsB00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 71.0 6.67e-01 98.7% 84.1%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.76 57.0 6.01e-01 100.0% 89.7%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 63.0 6.29e-01 100.0% 89.6%
3terA00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 67.0 5.70e-01 100.0% 63.0%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.73 68.0 5.98e-01 100.0% 70.8%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.72 63.0 6.16e-01 100.0% 88.7%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.72 57.0 5.00e-01 100.0% 56.9%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 63.0 6.52e-01 94.7% 100.0%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.72 58.0 4.81e-01 100.0% 49.6%
2zdiC00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 66.0 5.16e-01 100.0% 85.1%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.71 65.0 5.43e-01 100.0% 60.0%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.71 63.0 5.16e-01 96.0% 55.4%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.70 44.0 4.77e-01 100.0% 77.4%
2ke4A00 6.10.140.470 Special › Helix non-globular › Helix Hairpins › 0.70 58.0 5.32e-01 100.0% 69.4%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.70 63.0 5.12e-01 100.0% 54.0%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 59.0 6.05e-01 97.3% 95.8%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 60.0 6.14e-01 97.3% 97.3%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.69 63.0 5.16e-01 100.0% 57.1%
4doyA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.69 61.0 4.58e-01 100.0% 40.4%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 60.0 6.10e-01 100.0% 97.3%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.69 62.0 4.96e-01 100.0% 52.5%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.68 61.0 4.55e-01 100.0% 40.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 61.0 4.28e-01 100.0% 36.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.68 61.0 5.83e-01 100.0% 96.6%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 61.0 5.56e-01 100.0% 75.0%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.67 48.0 4.49e-01 86.7% 60.9%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 58.0 5.67e-01 96.0% 97.6%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.67 60.0 5.97e-01 100.0% 94.9%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.67 60.0 5.41e-01 100.0% 82.4%
1pd3A00 1.10.287.230 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 46.0 5.27e-01 89.3% 100.0%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.67 60.0 5.88e-01 100.0% 96.3%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 60.0 4.20e-01 100.0% 33.6%
2qywA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.67 55.0 5.13e-01 93.3% 71.6%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.66 60.0 4.68e-01 100.0% 52.3%
6tejB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.65 58.0 3.85e-01 100.0% 25.3%
2yksA02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.65 54.0 4.58e-01 90.7% 56.4%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.65 51.0 5.11e-01 90.7% 82.9%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 57.0 5.11e-01 100.0% 70.2%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.64 53.0 4.50e-01 90.7% 55.4%
3udcA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 54.0 4.65e-01 100.0% 59.1%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.63 51.0 5.16e-01 97.3% 87.8%
1zoyA03 1.20.58.100 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain 0.63 57.0 4.81e-01 98.7% 62.4%
2ieqA00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.62 55.0 5.26e-01 100.0% 96.6%
4od4A02 1.20.120.1780 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › UbiA prenyltransferase 0.62 53.0 4.53e-01 97.3% 58.8%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.62 52.0 4.36e-01 90.7% 56.8%
4modA00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 52.0 5.25e-01 96.0% 92.1%
5jazA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.60 40.0 3.75e-01 92.0% 56.0%
3tbiB02 6.10.140.1670 Special › Helix non-globular › Helix Hairpins › 0.60 54.0 4.90e-01 100.0% 88.0%
4hhyC01 1.20.142.10 Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain 0.60 50.0 4.20e-01 93.3% 62.6%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 49.0 5.08e-01 96.0% 100.0%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.59 54.0 3.93e-01 100.0% 80.1%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 52.0 3.80e-01 100.0% 81.4%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 52.0 5.05e-01 100.0% 91.8%
2fzlA02 6.10.140.1180 Special › Helix non-globular › Helix Hairpins › 0.58 44.0 4.74e-01 81.3% 98.4%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.57 48.0 4.46e-01 98.7% 74.2%
2oyhA00 1.20.5.50 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 44.0 4.65e-01 84.0% 100.0%
3khkB01 1.20.1260.30 Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain 0.55 49.0 3.81e-01 97.3% 73.6%
2wvnA01 1.20.120.1020 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Prion-inhibition and propagation, HeLo domain 0.55 48.0 3.41e-01 94.7% 35.2%
1h6vA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 47.0 3.26e-01 92.0% 42.7%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 44.0 3.50e-01 88.0% 45.9%
3kw2B02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.53 37.0 2.87e-01 73.3% 98.8%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3215342 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.82 67.0 6.11e-01 100.0% 68.4%
3273941 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.79 71.0 4.88e-01 100.0% 31.3%
5049840 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.78 62.0 6.28e-01 100.0% 86.7%
3512591 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.77 63.0 4.22e-01 100.0% 25.0%
4027897 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.77 68.0 6.16e-01 100.0% 72.0%
3502658 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.77 72.0 5.62e-01 100.0% 51.7%
3500503 192.8.1.300 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › SOAR 0.76 71.0 6.03e-01 100.0% 67.8%
3717072 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.76 71.0 5.56e-01 100.0% 52.4%
3692753 5086.1.1.12 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 0.76 70.0 5.45e-01 100.0% 50.0%
3277724 150.5.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.75 70.0 6.40e-01 100.0% 78.9%
3478220 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.75 66.0 5.98e-01 100.0% 72.0%
3946159 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.75 67.0 6.76e-01 100.0% 96.0%
3628093 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.75 66.0 5.88e-01 100.0% 68.6%
3945620 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.75 67.0 6.26e-01 100.0% 80.0%
3500290 101.1.12.0 alpha arrays › HTH › HTH › HTH motif inserted in other structures 0.74 67.0 6.58e-01 100.0% 91.3%
3494198 328.7.1.0 a+b two layers › IF3-like › Smr domain › Smr domain 0.74 68.0 4.96e-01 100.0% 43.2%
3487583 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.74 68.0 5.06e-01 100.0% 42.9%
3599499 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 68.0 5.30e-01 100.0% 50.0%
4029042 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.73 61.0 4.36e-01 100.0% 31.4%
3225754 632.6.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit › Plasmid maintenance system epsilon/zeta, antidote epsilon subunit 0.73 49.0 4.49e-01 90.7% 54.7%
3971109 5086.1.1.85 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AAEA_pHBA 0.73 64.0 6.43e-01 98.7% 94.7%
3912535 603.2.1.1 alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.73 67.0 4.83e-01 100.0% 42.1%
3711734 3755.3.1.297 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 0.73 67.0 5.07e-01 100.0% 45.5%
3857880 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 67.0 5.28e-01 100.0% 51.7%
4028685 192.2.1.1 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.72 66.0 5.78e-01 100.0% 77.3%
3448091 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 66.0 5.71e-01 100.0% 65.8%
3712650 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.72 67.0 5.82e-01 100.0% 86.4%
3496367 603.2.1.0 alpha bundles › STAT-like › STAT › STAT 0.72 65.0 4.61e-01 100.0% 34.4%
4629785 3922.1.1.269 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Rad50_zn_hook 0.72 66.0 4.32e-01 100.0% 96.2%
4957994 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 66.0 4.22e-01 100.0% 26.2%
3988581 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 64.0 6.05e-01 97.3% 96.7%
3623366 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.71 65.0 5.18e-01 100.0% 52.4%
3174178 632.22.1.153 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › AIP3 0.71 65.0 4.84e-01 100.0% 42.9%
3839126 5069.1.1.2 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ni_hydr_CYTB 0.71 61.0 4.58e-01 100.0% 38.9%
3487862 212.1.1.0 a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like 0.71 65.0 4.44e-01 100.0% 31.2%
4025636 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 64.0 4.97e-01 100.0% 67.7%
3612019 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 52.0 4.92e-01 88.0% 65.6%
4507175 3285.1.1.1 alpha duplicates or obligate multimers › Alix V domain › Alix V domain › Alix V domain › ALIX_LYPXL_bnd 0.70 64.0 4.15e-01 100.0% 24.8%
3184140 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.70 60.0 5.21e-01 100.0% 61.7%
4170329 605.1.1.158 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PsiE 0.70 57.0 4.76e-01 97.3% 51.5%
5054860 3755.3.1.305 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook 0.70 63.0 4.66e-01 100.0% 51.9%
3635376 3755.3.1.298 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING 0.69 63.0 5.14e-01 100.0% 60.7%
3787688 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 62.0 5.09e-01 100.0% 55.6%
3192264 7076.1.1.0 0.69 63.0 5.68e-01 100.0% 76.0%
5014330 148.1.3.402 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › Rad50_zn_hook 0.68 62.0 5.42e-01 100.0% 86.4%
4530254 2004.1.1.348 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SbcC_Walker_B 0.68 61.0 3.65e-01 100.0% 14.0%
3636338 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.68 62.0 5.18e-01 100.0% 76.8%
4107066 2004.1.1.348 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SbcC_Walker_B 0.68 61.0 3.62e-01 100.0% 14.0%
3988260 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.68 61.0 3.94e-01 100.0% 46.2%
3924998 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.68 60.0 3.83e-01 100.0% 20.8%
4403218 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.68 62.0 5.47e-01 100.0% 71.4%
4988993 5086.1.1.231 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook 0.67 60.0 4.78e-01 100.0% 52.7%
3787585 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.67 61.0 5.45e-01 100.0% 71.4%
4304214 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.67 62.0 5.29e-01 100.0% 65.2%
3698113 604.1.1.132 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › KAR9 0.67 60.0 4.98e-01 100.0% 69.2%
3897507 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.67 58.0 5.28e-01 96.0% 72.0%
3565692 11.2.1.14 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › RPGR1_C 0.67 60.0 3.55e-01 100.0% 14.0%
3901573 604.12.1.97 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PMP22_Claudin 0.67 60.0 5.26e-01 100.0% 74.5%
3447097 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.66 59.0 5.21e-01 100.0% 70.9%
3939746 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.66 59.0 4.49e-01 100.0% 44.6%
4144425 150.5.1.94 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PKHD_C 0.66 59.0 5.95e-01 98.7% 100.0%
3469730 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 58.0 5.20e-01 97.3% 69.5%
4607020 192.2.1.3 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Rad50_zn_hook 0.66 59.0 4.87e-01 100.0% 78.5%
3552608 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.65 58.0 4.62e-01 100.0% 91.3%
3710351 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.65 57.0 4.40e-01 100.0% 61.7%
3574240 5069.1.1.6 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › COX15-CtaA 0.65 54.0 3.53e-01 92.0% 50.6%
3516641 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 56.0 4.38e-01 100.0% 47.5%
5042044 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.63 54.0 4.54e-01 100.0% 55.4%
3629045 601.2.1.5 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr 0.63 55.0 4.70e-01 100.0% 60.8%
3355757 3910.1.1.4 extended segments › Exosome complex exonuclease RRP6 N-terminal domain › Exosome complex exonuclease RRP6 N-terminal domain › Exosome complex exonuclease RRP6 N-terminal domain › AATF-Che1 0.61 53.0 3.66e-01 98.7% 28.2%
3458020 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 52.0 3.90e-01 97.3% 38.4%
3881428 3835.1.1.1 alpha bundles › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › Type I hyperactive antifreeze protein › PLC-beta_C 0.60 55.0 4.04e-01 100.0% 41.1%
4979047 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 51.0 4.06e-01 100.0% 46.1%
3221299 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.59 52.0 4.33e-01 100.0% 55.6%
4020727 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 48.0 4.11e-01 100.0% 60.8%
D2 medium residues 203-389
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01528.23 best Herpes_glycop 162.2 2.60e-47 92.0% 49.0%
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.74 29.0 4.34e-01 74.9% 81.2%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.70 33.0 3.59e-01 84.5% 52.3%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.67 31.0 3.53e-01 82.9% 55.4%
2b1eA04 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.66 44.0 5.20e-01 71.1% 97.6%
2vixA03 1.20.1280.240 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.61 32.0 3.89e-01 70.6% 78.8%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 35.0 3.56e-01 84.0% 55.9%
1ohuA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.60 33.0 3.55e-01 78.1% 60.0%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.58 42.0 4.54e-01 74.3% 96.1%
1x04A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 34.0 3.41e-01 82.9% 54.5%
1axdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 34.0 4.13e-01 73.3% 89.4%
3i2wA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 34.0 3.07e-01 87.2% 41.9%
2pfdA03 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.56 46.0 4.50e-01 85.6% 79.3%
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.56 41.0 4.02e-01 77.0% 69.8%
7nc3F01 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 33.0 4.09e-01 80.2% 98.2%
4hz4A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 32.0 3.94e-01 86.6% 98.2%
5fhiA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 34.0 3.82e-01 82.9% 84.2%
8a1gC01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 37.0 3.79e-01 84.5% 75.7%
ECOD (32)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3837397 310.2.1.57 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF7798 0.79 57.0 6.15e-01 73.8% 93.8%
4933351 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.75 36.0 3.70e-01 85.6% 47.6%
4027582 603.1.1.120 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF846 0.71 45.0 5.54e-01 72.2% 100.0%
3283147 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.68 57.0 5.05e-01 87.7% 81.2%
3198072 109.4.1.381 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Rrn11 0.65 47.0 4.11e-01 74.3% 50.2%
3486005 109.4.1.228 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C 0.65 52.0 3.91e-01 83.4% 58.0%
3690080 603.5.1.0 alpha bundles › STAT-like › FlgN-like › FlgN-like 0.63 40.0 4.87e-01 79.1% 99.2%
3657913 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.61 38.0 3.95e-01 71.7% 63.9%
3743496 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.59 34.0 3.22e-01 89.3% 44.8%
3803813 603.2.1.44 alpha bundles › STAT-like › STAT › STAT › TPR_SYVN1_N 0.59 45.0 4.04e-01 78.1% 63.1%
4974860 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.58 40.0 3.99e-01 85.6% 67.2%
3402136 4177.1.1.8 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 0.58 35.0 3.21e-01 87.2% 45.7%
4960821 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.57 40.0 3.95e-01 89.8% 65.4%
4030233 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.57 48.0 4.81e-01 89.3% 92.3%
4945061 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.56 41.0 4.04e-01 88.8% 70.5%
4297837 603.3.1.1 alpha bundles › STAT-like › CAPPD, an extracellular domain of amyloid beta A4 protein › CAPPD, an extracellular domain of amyloid beta A4 protein › APP_E2 0.55 46.0 4.26e-01 86.6% 85.2%
4026288 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.55 42.0 4.00e-01 90.9% 68.0%
3287949 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.55 39.0 3.87e-01 72.7% 73.3%
3700079 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.54 41.0 3.87e-01 77.0% 68.9%
3786756 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.54 41.0 3.92e-01 88.8% 66.2%
3941867 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.54 40.0 3.93e-01 77.0% 68.6%
3293363 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 42.0 3.93e-01 87.7% 67.0%
3722567 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 40.0 3.85e-01 88.2% 67.3%
3608336 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.53 39.0 4.08e-01 94.1% 81.8%
4202769 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 41.0 3.98e-01 92.0% 71.9%
5064159 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 41.0 3.93e-01 91.4% 69.5%
3373563 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 40.0 3.68e-01 88.2% 60.4%
4236667 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.53 42.0 3.82e-01 84.0% 89.8%
5077923 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.51 41.0 4.18e-01 84.5% 100.0%
4031685 5079.1.1.1 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE 0.51 36.0 3.59e-01 80.7% 70.0%
4315478 150.8.1.5 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › EspA_EspE 0.51 36.0 3.70e-01 84.5% 73.5%
5031890 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.50 42.0 3.80e-01 87.7% 99.6%