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envelope_glycoprotein_M
Euk-VirTestudinid_alphaherpesvirus_3
envelope_glycoprotein_M__YP_009176930__Testudinid_alphaherpesvirus_3__2560801
Identity
- Accession:
- YP_009176930 ↗
- Protein ID:
- envelope_glycoprotein_M
- Kingdom:
- euk
Quality
78.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Scutavirus›
Testudinid_alphaherpesvirus_3
TaxID: 2560801
Cluster
View cluster (76 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 21-51_67-230
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 157.5 | 6.80e-46 | 100.0% | 63.0% |
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.83 | 51.0 | 6.47e-01 | 81.5% | 100.0% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.82 | 51.0 | 5.84e-01 | 80.5% | 82.3% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.80 | 48.0 | 6.12e-01 | 72.8% | 100.0% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.79 | 49.0 | 5.53e-01 | 81.0% | 79.5% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.78 | 38.0 | 4.58e-01 | 73.3% | 68.5% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.76 | 44.0 | 5.69e-01 | 86.7% | 100.0% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.74 | 60.0 | 5.16e-01 | 85.1% | 83.2% |
| 4k1pE00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.74 | 57.0 | 4.71e-01 | 79.0% | 88.6% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.72 | 58.0 | 4.83e-01 | 84.1% | 83.3% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.72 | 56.0 | 4.61e-01 | 81.5% | 86.4% |
| 2fefA01 | 1.20.1440.70 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › PA2201 N-terminal domain-like | 0.71 | 45.0 | 5.58e-01 | 74.9% | 99.2% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.71 | 51.0 | 4.85e-01 | 72.3% | 93.7% |
| 7zxkC01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.70 | 42.0 | 4.76e-01 | 75.9% | 77.3% |
| 7nmqA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.69 | 57.0 | 4.62e-01 | 85.1% | 87.7% |
| 1ciyA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.69 | 47.0 | 4.55e-01 | 74.4% | 61.1% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 45.0 | 5.19e-01 | 78.5% | 93.4% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 50.0 | 5.14e-01 | 77.4% | 96.3% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.67 | 46.0 | 4.99e-01 | 80.0% | 82.4% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.67 | 48.0 | 4.52e-01 | 78.5% | 61.6% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.66 | 39.0 | 4.80e-01 | 97.4% | 91.8% |
| 1eq1A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.66 | 45.0 | 4.81e-01 | 76.9% | 80.1% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 49.0 | 5.46e-01 | 84.1% | 98.1% |
| 2vgxB00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 31.0 | 3.54e-01 | 98.5% | 60.7% |
| 2or0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 51.0 | 5.21e-01 | 91.8% | 87.6% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 49.0 | 5.13e-01 | 90.3% | 90.3% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.61 | 38.0 | 4.37e-01 | 89.2% | 82.2% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 54.0 | 5.09e-01 | 94.9% | 83.4% |
| 1zb1A00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.60 | 45.0 | 3.61e-01 | 76.4% | 72.8% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 30.0 | 3.29e-01 | 88.2% | 58.2% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 44.0 | 3.99e-01 | 77.4% | 80.2% |
| 4p3gD00 | 1.10.3450.40 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › Signal recognition particle, SRP68 subunit, RNA-binding domain | 0.57 | 39.0 | 3.91e-01 | 94.9% | 67.7% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.56 | 43.0 | 4.68e-01 | 100.0% | 96.3% |
| 4bg5B00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.55 | 43.0 | 4.32e-01 | 82.6% | 97.0% |
| 2hs5A02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.54 | 28.0 | 3.28e-01 | 76.4% | 67.1% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 31.0 | 2.97e-01 | 84.1% | 46.8% |
| 4alyB00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.52 | 39.0 | 3.97e-01 | 76.4% | 96.3% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 37.0 | 3.95e-01 | 82.1% | 83.3% |
| 4mycA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.51 | 44.0 | 3.73e-01 | 93.3% | 96.6% |
ECOD (81)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3994022 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.82 | 58.0 | 6.83e-01 | 91.3% | 100.0% |
| 3485664 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.82 | 54.0 | 6.51e-01 | 85.6% | 99.2% |
| 4092983 | 3861.1.1.1 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR | 0.80 | 60.0 | 6.58e-01 | 99.5% | 93.8% |
| 3879044 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.79 | 51.0 | 6.25e-01 | 74.9% | 100.0% |
| 3773479 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.79 | 52.0 | 6.30e-01 | 78.5% | 100.0% |
| 3996622 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.79 | 57.0 | 6.58e-01 | 85.6% | 100.0% |
| 3806463 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 49.0 | 5.46e-01 | 83.1% | 78.1% |
| 3911777 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.78 | 54.0 | 6.34e-01 | 85.1% | 100.0% |
| 3765032 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.78 | 56.0 | 6.44e-01 | 86.2% | 98.6% |
| 3185833 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.78 | 59.0 | 6.67e-01 | 85.6% | 100.0% |
| 3622094 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.78 | 57.0 | 6.34e-01 | 85.1% | 94.2% |
| 3866648 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.78 | 61.0 | 6.65e-01 | 84.6% | 98.1% |
| 3607681 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.78 | 53.0 | 6.21e-01 | 81.5% | 98.5% |
| 3617743 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.78 | 57.0 | 6.49e-01 | 81.0% | 100.0% |
| 3888824 | 601.1.2.11 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CD20 | 0.78 | 55.0 | 6.18e-01 | 84.1% | 93.3% |
| 3400366 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.77 | 54.0 | 6.31e-01 | 85.1% | 99.3% |
| 3882493 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.77 | 56.0 | 6.28e-01 | 78.5% | 94.2% |
| 5057191 | 3861.1.1.1 ↗ | alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR | 0.77 | 57.0 | 6.27e-01 | 98.5% | 93.1% |
| 3525698 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.77 | 53.0 | 6.23e-01 | 76.4% | 100.0% |
| 3445025 | 174.1.1.2 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Jagunal | 0.77 | 54.0 | 6.01e-01 | 83.1% | 89.7% |
| 4017168 | 150.1.1.114 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF30036 | 0.76 | 58.0 | 6.48e-01 | 81.0% | 99.4% |
| 3824159 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.76 | 51.0 | 5.56e-01 | 88.7% | 80.0% |
| 3495283 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 51.0 | 6.06e-01 | 85.6% | 98.5% |
| 3826980 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.76 | 48.0 | 5.32e-01 | 78.5% | 77.5% |
| 3876677 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 60.0 | 6.40e-01 | 83.6% | 94.1% |
| 3503768 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.76 | 55.0 | 6.14e-01 | 81.5% | 95.3% |
| 3939799 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 53.0 | 6.22e-01 | 76.9% | 100.0% |
| 3236500 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.75 | 51.0 | 6.11e-01 | 83.1% | 100.0% |
| 3762118 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.75 | 60.0 | 6.51e-01 | 83.6% | 98.2% |
| 3406569 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.75 | 53.0 | 6.11e-01 | 81.5% | 100.0% |
| 3230188 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.74 | 55.0 | 6.18e-01 | 84.1% | 98.7% |
| 3917447 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 51.0 | 5.87e-01 | 80.5% | 95.7% |
| 3548233 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.74 | 60.0 | 6.52e-01 | 85.1% | 100.0% |
| 3494045 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 55.0 | 6.16e-01 | 82.6% | 98.0% |
| 3927012 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 52.0 | 6.03e-01 | 81.0% | 99.3% |
| 3999007 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.74 | 57.0 | 6.36e-01 | 79.5% | 100.0% |
| 4398872 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.74 | 57.0 | 6.28e-01 | 85.1% | 97.5% |
| 3873866 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.74 | 59.0 | 6.10e-01 | 82.1% | 98.3% |
| 3390014 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.74 | 54.0 | 6.10e-01 | 83.6% | 98.0% |
| 3856927 | 633.23.1.34 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CD20 | 0.74 | 60.0 | 6.32e-01 | 84.6% | 94.9% |
| 3711717 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 59.0 | 6.26e-01 | 99.5% | 95.3% |
| 4024396 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 50.0 | 6.00e-01 | 83.6% | 100.0% |
| 3911582 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.73 | 55.0 | 6.19e-01 | 83.1% | 100.0% |
| 3724953 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.73 | 56.0 | 6.21e-01 | 87.2% | 98.7% |
| 3263791 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 55.0 | 6.14e-01 | 84.6% | 99.3% |
| 3756853 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.73 | 60.0 | 6.08e-01 | 85.1% | 87.4% |
| 3248267 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 52.0 | 5.97e-01 | 89.7% | 98.6% |
| 3484519 | 633.10.1.22 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › SCAMP | 0.73 | 57.0 | 6.29e-01 | 91.3% | 100.0% |
| 3212117 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 57.0 | 6.24e-01 | 88.2% | 100.0% |
| 3475661 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 52.0 | 5.92e-01 | 85.1% | 97.9% |
| 3725105 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.72 | 59.0 | 5.50e-01 | 86.2% | 98.4% |
| 3998921 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.72 | 54.0 | 6.06e-01 | 79.0% | 100.0% |
| 3226467 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.72 | 49.0 | 5.80e-01 | 74.9% | 100.0% |
| 3662200 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.72 | 47.0 | 5.26e-01 | 90.8% | 83.2% |
| 5043625 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.71 | 50.0 | 5.60e-01 | 72.8% | 92.7% |
| 3592688 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.71 | 58.0 | 5.93e-01 | 85.1% | 95.1% |
| 3238154 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 58.0 | 6.02e-01 | 85.1% | 95.0% |
| 4979030 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.70 | 51.0 | 5.85e-01 | 82.6% | 100.0% |
| 3508320 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 55.0 | 6.04e-01 | 84.6% | 98.8% |
| 3407613 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.70 | 48.0 | 5.56e-01 | 85.6% | 97.8% |
| 3224526 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.69 | 52.0 | 5.84e-01 | 79.5% | 100.0% |
| 3748303 | 174.1.1.52 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27925 | 0.69 | 52.0 | 5.79e-01 | 81.0% | 100.0% |
| 3997790 | 174.1.1.31 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7027 | 0.69 | 51.0 | 5.51e-01 | 83.1% | 89.6% |
| 3203461 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.69 | 54.0 | 4.64e-01 | 86.2% | 53.0% |
| 3357886 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.69 | 52.0 | 5.43e-01 | 91.8% | 84.4% |
| 3985371 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.67 | 43.0 | 4.05e-01 | 83.1% | 52.3% |
| 3399533 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.67 | 47.0 | 5.19e-01 | 84.6% | 89.7% |
| 4540510 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.66 | 53.0 | 5.64e-01 | 84.6% | 95.3% |
| 51377 | 5000.4.1.0 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain | 0.66 | 47.0 | 4.46e-01 | 75.9% | 61.7% |
| 5070606 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.65 | 44.0 | 5.18e-01 | 80.0% | 100.0% |
| 4287641 | 5000.4.1.1 ↗ | alpha arrays › Toxins' membrane translocation domains › delta-Endotoxin (insectocide), N-terminal domain › delta-Endotoxin (insectocide), N-terminal domain › Endotoxin_N | 0.64 | 50.0 | 4.39e-01 | 82.1% | 61.4% |
| 3396860 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.63 | 45.0 | 5.19e-01 | 85.1% | 100.0% |
| 3923614 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.62 | 48.0 | 5.25e-01 | 83.6% | 98.8% |
| 4948636 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.62 | 56.0 | 5.52e-01 | 98.5% | 93.3% |
| 3798353 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 45.0 | 5.08e-01 | 82.1% | 100.0% |
| 3793248 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.60 | 46.0 | 4.93e-01 | 84.1% | 92.7% |
| 3491032 | 174.1.1.76 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Far-17a_AIG1 | 0.59 | 47.0 | 4.82e-01 | 84.1% | 96.8% |
| 4948739 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 50.0 | 4.95e-01 | 94.9% | 92.8% |
| 3912641 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.56 | 45.0 | 4.20e-01 | 84.6% | 71.8% |
| 4637398 | 3684.1.1.10 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF677 | 0.54 | 51.0 | 4.41e-01 | 100.0% | 80.0% |
| 3733697 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.51 | 44.0 | 3.43e-01 | 95.4% | 69.1% |
D2
medium
residues 231-337
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 89.1 | 4.30e-25 | 100.0% | 30.1% |
CATH (54)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.85 | 61.0 | 6.29e-01 | 72.9% | 83.0% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.85 | 60.0 | 6.61e-01 | 72.9% | 97.7% |
| 3r6nB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.83 | 75.0 | 5.74e-01 | 100.0% | 45.5% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 57.0 | 5.21e-01 | 72.9% | 67.6% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 75.0 | 6.88e-01 | 100.0% | 86.0% |
| 1kmiZ02 | 1.10.287.500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.81 | 57.0 | 5.26e-01 | 72.9% | 94.0% |
| 2g38B00 | 1.20.1260.20 | Mainly Alpha › Up-down Bundle › Ferritin › PPE superfamily | 0.80 | 56.0 | 4.69e-01 | 72.0% | 47.4% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.79 | 72.0 | 7.02e-01 | 98.1% | 100.0% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.79 | 56.0 | 5.01e-01 | 72.9% | 61.6% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 56.0 | 4.17e-01 | 72.9% | 33.3% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.79 | 56.0 | 4.29e-01 | 73.8% | 42.7% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 55.0 | 4.38e-01 | 72.9% | 47.4% |
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.78 | 72.0 | 5.68e-01 | 100.0% | 90.4% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 69.0 | 7.05e-01 | 95.3% | 100.0% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.78 | 69.0 | 6.38e-01 | 96.3% | 82.2% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.77 | 53.0 | 6.14e-01 | 89.7% | 98.7% |
| 5y06A01 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 54.0 | 4.18e-01 | 72.9% | 50.2% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.77 | 53.0 | 6.14e-01 | 74.8% | 100.0% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 53.0 | 4.63e-01 | 72.0% | 80.1% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.77 | 58.0 | 6.24e-01 | 86.9% | 93.4% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 54.0 | 5.51e-01 | 72.0% | 78.4% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.76 | 70.0 | 4.95e-01 | 100.0% | 88.5% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.76 | 65.0 | 5.17e-01 | 93.5% | 58.8% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 63.0 | 6.33e-01 | 91.6% | 97.2% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 59.0 | 6.10e-01 | 85.0% | 98.0% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.74 | 53.0 | 6.01e-01 | 72.9% | 98.8% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 67.0 | 6.39e-01 | 98.1% | 95.1% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 61.0 | 5.77e-01 | 88.8% | 75.0% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.74 | 58.0 | 5.92e-01 | 86.0% | 87.3% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.74 | 65.0 | 6.54e-01 | 98.1% | 98.1% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 52.0 | 3.99e-01 | 72.9% | 47.0% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.73 | 51.0 | 4.72e-01 | 71.0% | 58.6% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 63.0 | 6.17e-01 | 96.3% | 100.0% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.72 | 62.0 | 6.41e-01 | 93.5% | 100.0% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.71 | 47.0 | 5.50e-01 | 72.0% | 100.0% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 55.0 | 5.54e-01 | 82.2% | 100.0% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 49.0 | 5.21e-01 | 72.9% | 97.9% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.69 | 59.0 | 5.92e-01 | 91.6% | 100.0% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.69 | 58.0 | 5.81e-01 | 90.7% | 99.1% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 61.0 | 5.48e-01 | 99.1% | 98.7% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 55.0 | 5.68e-01 | 86.9% | 100.0% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.69 | 45.0 | 5.12e-01 | 74.8% | 91.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 57.0 | 6.02e-01 | 97.2% | 100.0% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 58.0 | 5.05e-01 | 91.6% | 95.6% |
| 2v0pA00 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.65 | 59.0 | 4.57e-01 | 96.3% | 74.3% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 53.0 | 4.37e-01 | 86.9% | 61.1% |
| 2l81A00 | 1.20.120.830 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain | 0.63 | 53.0 | 4.53e-01 | 92.5% | 61.9% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 52.0 | 4.73e-01 | 94.4% | 99.3% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.61 | 40.0 | 3.85e-01 | 78.5% | 58.1% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.60 | 56.0 | 4.80e-01 | 100.0% | 92.5% |
| 1jogA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 46.0 | 4.28e-01 | 84.1% | 85.9% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.56 | 45.0 | 4.53e-01 | 86.9% | 97.3% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 46.0 | 4.69e-01 | 100.0% | 97.2% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 44.0 | 3.99e-01 | 98.1% | 71.3% |
ECOD (71)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3576407 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.86 | 75.0 | 7.29e-01 | 91.6% | 100.0% |
| 3760483 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.86 | 61.0 | 4.90e-01 | 72.9% | 43.7% |
| 5006401 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.85 | 60.0 | 5.37e-01 | 72.9% | 64.8% |
| 3613932 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.85 | 60.0 | 5.88e-01 | 72.9% | 78.3% |
| 4601110 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.85 | 60.0 | 4.16e-01 | 72.9% | 25.3% |
| 3772767 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.84 | 60.0 | 5.64e-01 | 72.9% | 63.2% |
| 3553813 | 3291.1.1.82 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING | 0.84 | 60.0 | 5.64e-01 | 72.9% | 63.2% |
| 4935333 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.82 | 58.0 | 5.12e-01 | 72.9% | 88.0% |
| 3752758 | 3755.3.1.467 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C | 0.82 | 57.0 | 5.09e-01 | 72.0% | 75.2% |
| 3479092 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.82 | 68.0 | 7.05e-01 | 92.5% | 94.0% |
| 4303085 | 3755.3.1.467 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C | 0.82 | 58.0 | 5.56e-01 | 72.9% | 68.3% |
| 3708236 | 633.6.1.6 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACAD9-ACADV_C | 0.81 | 51.0 | 5.23e-01 | 71.0% | 65.7% |
| 3794663 | 604.3.1.27 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › EMC4 | 0.81 | 70.0 | 7.28e-01 | 92.5% | 99.0% |
| 3301242 | 605.4.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF2499 | 0.81 | 45.0 | 4.76e-01 | 70.1% | 62.1% |
| 3781506 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.80 | 55.0 | 4.79e-01 | 70.1% | 85.2% |
| 4537898 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.80 | 57.0 | 4.05e-01 | 72.9% | 28.4% |
| 4156473 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.80 | 50.0 | 5.31e-01 | 72.0% | 71.6% |
| 3586386 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.79 | 56.0 | 3.92e-01 | 72.9% | 43.8% |
| 3598261 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.79 | 73.0 | 6.40e-01 | 100.0% | 100.0% |
| 3412004 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.79 | 68.0 | 7.08e-01 | 92.5% | 100.0% |
| 3477269 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.79 | 58.0 | 5.03e-01 | 75.7% | 94.2% |
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.79 | 56.0 | 4.77e-01 | 72.9% | 57.0% |
| 4941191 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.79 | 51.0 | 5.13e-01 | 71.0% | 64.5% |
| 3923798 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.79 | 54.0 | 4.14e-01 | 71.0% | 43.4% |
| 3474661 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.79 | 68.0 | 6.64e-01 | 91.6% | 91.3% |
| 2722819 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.79 | 71.0 | 5.50e-01 | 100.0% | 84.3% |
| 3336125 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.78 | 72.0 | 6.11e-01 | 100.0% | 67.1% |
| 4025809 | 604.6.1.22 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 | 0.78 | 66.0 | 6.54e-01 | 89.7% | 86.4% |
| 3558580 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.78 | 55.0 | 3.74e-01 | 72.9% | 22.2% |
| 4065692 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.78 | 56.0 | 6.07e-01 | 85.0% | 88.9% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.78 | 55.0 | 4.75e-01 | 72.9% | 60.6% |
| 4988623 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.77 | 55.0 | 4.02e-01 | 72.9% | 37.0% |
| 3216480 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.77 | 54.0 | 3.83e-01 | 72.0% | 26.6% |
| 3597260 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.77 | 55.0 | 4.61e-01 | 72.9% | 75.3% |
| 3804937 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.77 | 54.0 | 4.71e-01 | 72.9% | 57.5% |
| 3337008 | 192.2.1.60 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th | 0.77 | 54.0 | 4.93e-01 | 72.9% | 64.3% |
| 3909538 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.76 | 64.0 | 6.49e-01 | 90.7% | 99.0% |
| 3504303 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.76 | 62.0 | 6.46e-01 | 87.9% | 99.0% |
| 3619687 | 604.1.1.127 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 | 0.76 | 65.0 | 6.52e-01 | 93.5% | 90.0% |
| 4002046 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.76 | 66.0 | 6.61e-01 | 95.3% | 93.6% |
| 3766955 | 192.7.1.17 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › FAM186A-B_C | 0.76 | 53.0 | 4.80e-01 | 72.9% | 75.2% |
| 3208120 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.76 | 66.0 | 5.79e-01 | 94.4% | 81.3% |
| 4345017 | 2004.1.1.433 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 | 0.75 | 53.0 | 3.25e-01 | 72.9% | 15.7% |
| 3919840 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.75 | 53.0 | 4.14e-01 | 72.9% | 39.1% |
| 4618995 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.75 | 63.0 | 6.55e-01 | 90.7% | 98.0% |
| 3225163 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.75 | 60.0 | 5.61e-01 | 86.0% | 86.2% |
| 4418753 | 3755.3.1.363 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T1-F | 0.74 | 56.0 | 4.05e-01 | 78.5% | 93.0% |
| 3739245 | 4177.1.1.14 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_2 | 0.74 | 52.0 | 4.12e-01 | 72.9% | 37.2% |
| 4983461 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.74 | 53.0 | 5.08e-01 | 73.8% | 78.3% |
| 3962352 | 192.29.1.146 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF2231 | 0.74 | 63.0 | 5.56e-01 | 92.5% | 66.0% |
| 55139 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.73 | 61.0 | 5.91e-01 | 90.7% | 86.1% |
| 3505434 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.73 | 66.0 | 6.26e-01 | 97.2% | 95.2% |
| 3572847 | 604.1.1.162 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4716 | 0.73 | 63.0 | 6.20e-01 | 94.4% | 94.8% |
| 3264853 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.73 | 65.0 | 6.04e-01 | 100.0% | 97.8% |
| 4020772 | 4207.1.1.64 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › PF30554 | 0.72 | 51.0 | 4.07e-01 | 72.9% | 89.8% |
| 4003767 | 603.1.1.136 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › HB_ELP1 | 0.71 | 64.0 | 5.52e-01 | 100.0% | 85.9% |
| 3207548 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.71 | 50.0 | 4.57e-01 | 72.9% | 97.9% |
| 3935030 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 62.0 | 6.26e-01 | 95.3% | 100.0% |
| 3943946 | 150.1.1.7 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF892 | 0.69 | 61.0 | 5.30e-01 | 98.1% | 95.2% |
| 3215082 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 48.0 | 4.51e-01 | 72.9% | 63.0% |
| 3190576 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 62.0 | 6.14e-01 | 94.4% | 94.5% |
| 4515899 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 48.0 | 4.12e-01 | 72.9% | 54.1% |
| 3746558 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.67 | 53.0 | 4.24e-01 | 84.1% | 85.7% |
| 5076586 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.67 | 56.0 | 5.83e-01 | 89.7% | 99.0% |
| 3497911 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.67 | 55.0 | 5.15e-01 | 89.7% | 81.5% |
| 3573621 | 5059.1.1.8 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA | 0.66 | 54.0 | 4.80e-01 | 91.6% | 65.6% |
| 3246493 | 2004.1.1.442 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 | 0.64 | 51.0 | 3.35e-01 | 86.0% | 69.0% |
| 3386700 | 304.58.1.0 ↗ | a+b two layers › Alpha-beta plaits › FepE-like › FepE-like | 0.64 | 52.0 | 3.71e-01 | 86.0% | 90.8% |
| 4092812 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.63 | 55.0 | 4.01e-01 | 100.0% | 84.6% |
| 4021462 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.63 | 44.0 | 2.75e-01 | 72.9% | 31.9% |
| 4969096 | 3926.1.1.0 ↗ | alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D | 0.61 | 53.0 | 4.04e-01 | 95.3% | 69.6% |