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envelope_glycoprotein_M
Euk-VirGallid_alphaherpesvirus_1
envelope_glycoprotein_M__YP_182385__Gallid_alphaherpesvirus_1__10386
Identity
- Accession:
- YP_182385 ↗
- Protein ID:
- envelope_glycoprotein_M
- Kingdom:
- euk
Quality
81.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Gallid_alphaherpesvirus_1
TaxID: 10386
Cluster
View cluster (76 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 12-259
Domain cluster:
rep: glycoprotein_M__YP_009551849__Rhinolophus_gammaherpesvirus_1__2054179__D5-329
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01528.23 best | Herpes_glycop | 183.6 | 8.20e-54 | 99.2% | 72.2% |
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.81 | 41.0 | 5.18e-01 | 73.0% | 79.5% |
| 7qx4A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.69 | 40.0 | 4.19e-01 | 70.6% | 60.7% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 43.0 | 5.12e-01 | 75.0% | 94.7% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.65 | 45.0 | 5.00e-01 | 94.0% | 86.5% |
| 2c9kA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.64 | 41.0 | 4.23e-01 | 70.2% | 65.3% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 42.0 | 4.92e-01 | 87.1% | 93.7% |
| 1elwA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 27.0 | 3.81e-01 | 94.4% | 81.2% |
| 4xi0F00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 28.0 | 3.28e-01 | 96.4% | 57.3% |
| 4yvoA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 30.0 | 4.28e-01 | 95.6% | 95.8% |
| 2fo7A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 27.0 | 3.65e-01 | 94.4% | 74.3% |
| 2vyiA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 28.0 | 3.84e-01 | 96.4% | 82.0% |
| 3i9yA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 46.0 | 4.84e-01 | 84.7% | 83.4% |
| 2hr2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 32.0 | 3.94e-01 | 98.4% | 80.1% |
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 35.0 | 3.69e-01 | 100.0% | 64.0% |
| 1zu2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 30.0 | 3.81e-01 | 92.3% | 79.1% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.58 | 25.0 | 3.22e-01 | 76.2% | 66.7% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.56 | 36.0 | 4.30e-01 | 96.0% | 96.3% |
| 4g1tA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 28.0 | 2.85e-01 | 96.0% | 46.7% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 27.0 | 3.32e-01 | 72.6% | 71.4% |
| 3x3bA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 37.0 | 3.64e-01 | 85.1% | 62.4% |
| 2g38B00 | 1.20.1260.20 | Mainly Alpha › Up-down Bundle › Ferritin › PPE superfamily | 0.54 | 36.0 | 4.23e-01 | 94.4% | 95.4% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 36.0 | 4.16e-01 | 95.2% | 97.2% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 37.0 | 4.21e-01 | 94.8% | 97.3% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 4.26e-01 | 96.0% | 88.4% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 38.0 | 3.66e-01 | 87.1% | 64.0% |
| 3r9mA00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.51 | 46.0 | 3.97e-01 | 100.0% | 62.8% |
ECOD (57)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3508320 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.81 | 49.0 | 6.01e-01 | 76.6% | 92.5% |
| 3326634 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.80 | 46.0 | 5.40e-01 | 77.0% | 78.9% |
| 3994022 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.80 | 46.0 | 6.08e-01 | 80.6% | 100.0% |
| 3351015 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.79 | 45.0 | 5.35e-01 | 77.0% | 78.9% |
| 3338353 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.79 | 42.0 | 5.24e-01 | 78.2% | 80.6% |
| 3828167 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 41.0 | 5.10e-01 | 77.0% | 78.8% |
| 3420292 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.78 | 42.0 | 5.39e-01 | 88.7% | 86.7% |
| 3806463 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.77 | 40.0 | 4.98e-01 | 74.2% | 78.7% |
| 3866648 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.77 | 49.0 | 5.99e-01 | 74.2% | 98.1% |
| 3712159 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.76 | 46.0 | 5.68e-01 | 85.9% | 93.5% |
| 3806117 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.76 | 40.0 | 5.01e-01 | 77.0% | 80.6% |
| 3814234 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.76 | 36.0 | 4.98e-01 | 73.4% | 86.2% |
| 3865873 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.76 | 49.0 | 6.02e-01 | 71.4% | 100.0% |
| 3724953 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.75 | 47.0 | 5.86e-01 | 76.2% | 98.7% |
| 3762118 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.74 | 49.0 | 5.90e-01 | 74.2% | 98.2% |
| 3346434 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.74 | 41.0 | 5.04e-01 | 80.2% | 83.1% |
| 3888824 | 601.1.2.11 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CD20 | 0.74 | 46.0 | 5.73e-01 | 72.6% | 100.0% |
| 3212117 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.74 | 47.0 | 5.88e-01 | 81.5% | 100.0% |
| 3831449 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.74 | 40.0 | 4.94e-01 | 77.0% | 81.9% |
| 4020850 | 3758.1.1.0 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins | 0.73 | 52.0 | 4.87e-01 | 71.0% | 80.3% |
| 3868831 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.73 | 47.0 | 5.65e-01 | 76.2% | 95.8% |
| 3485310 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.73 | 42.0 | 5.50e-01 | 75.4% | 100.0% |
| 3899721 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.73 | 48.0 | 5.76e-01 | 76.2% | 98.2% |
| 3876677 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.73 | 49.0 | 5.82e-01 | 76.2% | 98.8% |
| 4398872 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.72 | 47.0 | 5.76e-01 | 76.2% | 100.0% |
| 3357886 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.72 | 44.0 | 5.18e-01 | 89.1% | 84.4% |
| 3911582 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.71 | 44.0 | 5.48e-01 | 74.6% | 100.0% |
| 3662200 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.70 | 39.0 | 4.79e-01 | 80.2% | 83.9% |
| 3238154 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.68 | 47.0 | 5.46e-01 | 76.2% | 96.1% |
| 5078457 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.66 | 48.0 | 5.21e-01 | 89.5% | 88.3% |
| 4948636 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.66 | 48.0 | 5.20e-01 | 91.5% | 87.6% |
| 3486899 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 34.0 | 3.67e-01 | 85.5% | 57.6% |
| 3645195 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.66 | 42.0 | 5.20e-01 | 80.2% | 100.0% |
| 5026949 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.65 | 48.0 | 5.18e-01 | 93.1% | 87.4% |
| 3491731 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.65 | 37.0 | 4.76e-01 | 73.8% | 99.3% |
| 5064299 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.64 | 47.0 | 5.02e-01 | 94.4% | 86.7% |
| 3436634 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.64 | 40.0 | 5.04e-01 | 71.8% | 100.0% |
| 5070606 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.64 | 36.0 | 4.75e-01 | 72.6% | 100.0% |
| 4200312 | 601.1.2.11 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CD20 | 0.64 | 47.0 | 5.35e-01 | 77.8% | 100.0% |
| 5060153 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.64 | 45.0 | 4.86e-01 | 90.3% | 84.3% |
| 4980421 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.63 | 46.0 | 4.86e-01 | 94.0% | 84.2% |
| 3990051 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.63 | 46.0 | 4.98e-01 | 96.8% | 88.5% |
| 3895743 | 3615.1.1.7 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › CD20 | 0.62 | 45.0 | 5.14e-01 | 76.6% | 96.8% |
| 3917171 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 37.0 | 4.28e-01 | 94.8% | 80.6% |
| 4564184 | 109.4.1.235 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 | 0.61 | 41.0 | 4.21e-01 | 98.4% | 70.2% |
| 4281566 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.56 | 46.0 | 4.05e-01 | 100.0% | 60.0% |
| 4940230 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 30.0 | 3.27e-01 | 70.2% | 60.0% |
| None | — | 0.56 | 36.0 | 3.91e-01 | 92.7% | 76.2% | |
| 3231382 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.55 | 43.0 | 3.98e-01 | 80.2% | 88.7% |
| 3998922 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.55 | 49.0 | 4.52e-01 | 94.8% | 83.4% |
| 3243362 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.55 | 41.0 | 3.71e-01 | 75.8% | 83.3% |
| 3989350 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.52 | 42.0 | 4.53e-01 | 83.1% | 100.0% |
| 3789447 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.51 | 38.0 | 4.02e-01 | 96.0% | 86.0% |
| 3241626 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.51 | 41.0 | 3.92e-01 | 92.7% | 70.5% |
| 3678302 | 109.4.1.496 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec5 | 0.51 | 31.0 | 2.77e-01 | 95.2% | 42.4% |
| 3682600 | 109.4.1.359 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C | 0.51 | 36.0 | 3.86e-01 | 96.8% | 82.8% |
| 3577239 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.50 | 38.0 | 3.87e-01 | 95.6% | 80.0% |
D2
medium
residues 347-386
Domain cluster:
representative