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envelope_protein_E
Euk-VirZika_virus
envelope_protein_E__YP_009227198__Zika_virus__64320
Identity
- Accession:
- YP_009227198 ↗
- Protein ID:
- envelope_protein_E
- Kingdom:
- euk
Quality
82.7
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Zika_virus
TaxID: 64320
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 8-52_130-190_281-290
Domain cluster:
rep: uncovered_polypeptide_truncated_polyprotein__YP_006485886_0-792__Murray_Valley_encephalitis_virus__11079__D299-336_439-487_569-589
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00869.26 best | Flavi_glycoprot | 68.0 | 1.20e-18 | 41.4% | 15.0% |
D2
high
residues 308-398
Domain cluster:
rep: envelope_protein__YP_009163750__Spanish_goat_encephalitis_virus__1691889__D312-394
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02832.23 best | Flavi_glycop_C | 101.6 | 2.90e-29 | 100.0% | 91.8% |
D3
medium
residues 55-128_231-256
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00869.26 best | Flavi_glycoprot | 117.5 | 1.00e-33 | 75.0% | 24.7% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ok8A03 | 3.30.387.10 | Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 3 › Viral Envelope Glycoprotein, domain 3 | 0.99 | 78.0 | 8.74e-01 | 90.0% | 100.0% |
| 2c7rA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.56 | 46.0 | 3.61e-01 | 89.0% | 46.9% |
| 3qv2A01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.54 | 43.0 | 3.43e-01 | 89.0% | 42.5% |
| 4h0nA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 43.0 | 3.40e-01 | 86.0% | 44.7% |
| 1fx3B00 | 3.10.420.10 | Alpha Beta › Roll › Bacterial Protein-export protein SecB › SecB-like | 0.53 | 44.0 | 3.89e-01 | 92.0% | 77.9% |
| 4mmhA02 | 2.70.98.70 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.51 | 42.0 | 3.13e-01 | 91.0% | 49.1% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4861488 | 5090.1.1.1 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Flavi_glycoprot | 0.97 | 94.0 | 6.36e-01 | 100.0% | 67.9% |
| 1935959 | 5090.1.1.1 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Flavi_glycoprot | 0.97 | 70.0 | 7.18e-01 | 74.0% | 76.3% |
| 2330240 | 5090.1.1.1 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Flavi_glycoprot | 0.95 | 92.0 | 6.17e-01 | 100.0% | 65.7% |
| 1839942 | 5090.1.1.5 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Phlebovirus_G2 | 0.75 | 68.0 | 4.69e-01 | 100.0% | 62.7% |
| 3247901 | 5090.1.1.5 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Phlebovirus_G2 | 0.72 | 64.0 | 4.63e-01 | 100.0% | 74.1% |
| 2531649 | 5090.1.1.5 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › Phlebovirus_G2 | 0.72 | 64.0 | 4.47e-01 | 100.0% | 64.1% |
| 3938228 | 5090.1.1.8 ↗ | beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains › EFF-AFF | 0.68 | 58.0 | 4.00e-01 | 94.0% | 63.2% |
| 3694783 | 327.16.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system | 0.54 | 45.0 | 3.86e-01 | 93.0% | 84.1% |
| 3918690 | 2003.1.5.1 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DNA_methylase | 0.54 | 43.0 | 2.96e-01 | 86.0% | 68.6% |
| 4392983 | 2003.1.5.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MethyltransfD12 | 0.52 | 39.0 | 2.83e-01 | 79.0% | 90.9% |
| 3535594 | 304.18.1.0 ↗ | a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS | 0.51 | 35.0 | 3.65e-01 | 80.0% | 78.9% |
D4
medium
residues 191-230_257-268
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00869.26 best | Flavi_glycoprot | 42.3 | 8.20e-11 | 76.9% | 12.3% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1okeB02 | 3.30.67.10 | Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 | 0.93 | 85.0 | 7.30e-01 | 98.1% | 72.7% |
| 6epkA02 | 3.30.67.10 | Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 | 0.92 | 82.0 | 7.30e-01 | 100.0% | 70.4% |
| 3p54A02 | 3.30.67.10 | Alpha Beta › 2-Layer Sandwich › Viral Envelope Glycoprotein; domain 2 › Viral Envelope Glycoprotein, domain 2 | 0.87 | 78.0 | 6.90e-01 | 100.0% | 70.4% |
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.53 | 41.0 | 2.49e-01 | 100.0% | 44.7% |
| 5zb2B00 | 3.30.710.10 | Alpha Beta › 2-Layer Sandwich › Potassium Channel Kv1.1; Chain A › Potassium Channel Kv1.1; Chain A | 0.52 | 41.0 | 3.65e-01 | 90.4% | 62.8% |
| 1i77A00 | 3.90.10.10 | Alpha Beta › Alpha-Beta Complex › Cytochrome C3 › Cytochrome C3 | 0.51 | 40.0 | 3.27e-01 | 92.3% | 93.5% |
| 1knvB00 | 3.40.91.10 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.50 | 38.0 | 2.46e-01 | 88.5% | 30.9% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3846283 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.65 | 47.0 | 4.79e-01 | 76.9% | 92.0% |
| 3619869 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.60 | 50.0 | 3.87e-01 | 96.2% | 57.5% |
| 2619966 | 593.1.1.1 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 | 0.59 | 36.0 | 2.72e-01 | 73.1% | 23.7% |
| 3783355 | 633.23.1.12 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › Fig1 | 0.55 | 37.0 | 2.53e-01 | 71.2% | 72.7% |
| 3301223 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.53 | 36.0 | 2.25e-01 | 76.9% | 69.4% |
| 4953042 | 2.14.1.1 ↗ | beta barrels › OB-fold › HupF/HypC-like › HupF/HypC-like › HupF_HypC | 0.52 | 37.0 | 3.28e-01 | 76.9% | 66.3% |
| 4031209 | 2003.1.10.9 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain › Lant_dehydr_N | 0.50 | 35.0 | 2.87e-01 | 100.0% | 40.0% |
D5
medium
residues 402-499