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envelope_protein_UL43

Euk-Vir

Meleagrid_alphaherpesvirus_1

envelope_protein_UL43__NP_073337__Meleagrid_alphaherpesvirus_1__37108

Identity

Accession:
NP_073337 ↗
Protein ID:
envelope_protein_UL43
Kingdom:
euk

Quality

74.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 268-421
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05072.19 best Herpes_UL43 57.9 1.40e-15 100.0% 40.7%
D2 medium residues 47-92_180-207
PDB
Domain cluster: representative
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.74 44.0 4.22e-01 100.0% 52.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.70 48.0 4.54e-01 70.3% 80.5%
2c2aA01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.70 53.0 4.94e-01 79.7% 87.8%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.69 48.0 4.35e-01 73.0% 73.5%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.69 53.0 5.23e-01 79.7% 80.5%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.69 49.0 4.70e-01 74.3% 91.8%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.69 46.0 4.59e-01 94.6% 66.7%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.69 55.0 4.47e-01 86.5% 73.3%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.66 51.0 4.50e-01 82.4% 59.4%
4ceiA03 6.10.250.2380 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.65 46.0 3.99e-01 73.0% 56.2%
7sf7A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.65 52.0 3.44e-01 83.8% 35.4%
6bl6B01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.65 56.0 3.67e-01 95.9% 83.2%
4gltA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 52.0 4.51e-01 87.8% 77.2%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 53.0 4.73e-01 89.2% 90.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.64 46.0 4.28e-01 75.7% 62.6%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 56.0 4.32e-01 95.9% 53.5%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 50.0 4.43e-01 89.2% 77.0%
1dlcA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.62 50.0 3.53e-01 86.5% 38.4%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.62 47.0 4.38e-01 100.0% 65.6%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 45.0 4.09e-01 77.0% 79.8%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 42.0 4.41e-01 73.0% 94.1%
3qavA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 50.0 4.15e-01 93.2% 90.7%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.59 41.0 3.99e-01 73.0% 86.6%
5h5mA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 43.0 3.57e-01 77.0% 53.1%
1rv2D04 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.58 42.0 4.29e-01 75.7% 85.7%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.57 44.0 4.39e-01 86.5% 94.9%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.56 41.0 3.97e-01 81.1% 89.7%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.56 49.0 3.20e-01 98.6% 82.8%
4k0dA00 1.20.120.1730 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 47.0 3.88e-01 100.0% 82.5%
5ojcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 44.0 3.49e-01 93.2% 95.5%
2dt7B01 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.52 39.0 4.37e-01 79.7% 100.0%
2y51A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.50 39.0 2.63e-01 83.8% 55.8%
6wk3A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 41.0 3.36e-01 91.9% 91.0%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3903982 633.23.1.10 alpha bundles › Bromodomain-like › Claudin › Claudin › Prominin 0.77 56.0 3.71e-01 75.7% 69.6%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.75 47.0 4.46e-01 98.6% 55.3%
3541698 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.75 53.0 4.19e-01 74.3% 92.4%
3184140 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.72 55.0 4.65e-01 79.7% 58.3%
4683346 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.71 50.0 4.95e-01 73.0% 91.1%
4630202 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.70 49.0 4.64e-01 73.0% 80.9%
3425693 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.69 47.0 4.40e-01 70.3% 84.4%
3993362 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.68 47.0 4.30e-01 73.0% 86.0%
3170882 603.1.1.210 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Tmemb_170 0.66 45.0 3.74e-01 97.3% 43.3%
3875765 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.66 51.0 3.34e-01 85.1% 87.0%
4109908 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.65 45.0 4.36e-01 73.0% 85.9%
3292746 192.29.1.25 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CA109-like 0.64 54.0 3.98e-01 93.2% 91.5%
4029754 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.64 51.0 4.83e-01 82.4% 88.2%
4977468 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.64 43.0 3.99e-01 79.7% 56.7%
3995294 1065.1.1.0 alpha bundles › SPX domain › SPX domain › SPX domain 0.63 45.0 3.78e-01 74.3% 54.4%
4179237 6028.1.1.0 alpha bundles › Ribosome modulation factor › Ribosome modulation factor › Ribosome modulation factor 0.59 46.0 4.90e-01 83.8% 98.5%
5046057 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.59 44.0 4.66e-01 82.4% 89.2%
4991390 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.59 45.0 4.14e-01 98.6% 63.2%
3602572 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.59 52.0 4.21e-01 100.0% 75.0%
4119449 109.4.1.1151 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HIR3_helical 0.57 48.0 3.21e-01 91.9% 54.4%
3559706 5073.1.1.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M 0.56 47.0 2.79e-01 93.2% 16.6%
D3 medium residues 93-179_208-224
PDB
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.84 54.0 4.60e-01 86.5% 43.6%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.83 59.0 6.44e-01 73.1% 89.4%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.81 54.0 4.69e-01 87.5% 47.0%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.79 54.0 4.64e-01 82.7% 47.4%
1jgcA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 54.0 4.60e-01 84.6% 46.3%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 54.0 4.49e-01 81.7% 43.8%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.78 54.0 4.17e-01 71.2% 34.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 54.0 5.76e-01 73.1% 82.6%
4mt4A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.76 53.0 3.36e-01 71.2% 15.9%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 52.0 3.78e-01 70.2% 28.0%
2v0xA01 1.10.287.3160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.75 60.0 5.03e-01 83.7% 89.3%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 52.0 3.88e-01 70.2% 31.4%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.75 54.0 5.92e-01 75.0% 100.0%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.75 61.0 4.99e-01 86.5% 93.4%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 51.0 5.08e-01 71.2% 68.2%
5u1aL00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 51.0 4.30e-01 76.9% 44.0%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 51.0 5.35e-01 71.2% 82.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.74 50.0 5.35e-01 71.2% 80.0%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.73 50.0 4.59e-01 70.2% 57.0%
1ek9A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.72 57.0 3.74e-01 83.7% 69.2%
1o5hA00 1.20.120.680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle 0.72 52.0 4.16e-01 75.0% 49.0%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.72 50.0 5.65e-01 71.2% 92.5%
4mrsA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.72 58.0 4.00e-01 85.6% 83.3%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.72 56.0 5.43e-01 80.8% 100.0%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.71 50.0 4.93e-01 73.1% 68.1%
5azsC01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.71 57.0 3.83e-01 83.7% 65.4%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.71 58.0 4.06e-01 86.5% 88.7%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.71 53.0 5.18e-01 77.9% 74.6%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 52.0 4.98e-01 76.9% 75.4%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.71 56.0 5.15e-01 82.7% 100.0%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.70 48.0 5.20e-01 71.2% 86.4%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 48.0 3.59e-01 71.2% 29.2%
1orsC00 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.70 56.0 5.12e-01 84.6% 97.0%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.69 56.0 4.76e-01 86.5% 78.1%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 51.0 4.74e-01 76.9% 80.0%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 48.0 5.43e-01 71.2% 100.0%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 47.0 3.75e-01 71.2% 36.7%
3smtA02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.68 54.0 4.60e-01 83.7% 73.8%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.68 47.0 4.30e-01 70.2% 56.7%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 50.0 4.81e-01 76.9% 100.0%
2rdcA00 1.10.287.800 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 0.68 55.0 5.03e-01 86.5% 86.5%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.67 49.0 4.70e-01 75.0% 78.6%
6vmsR00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.67 53.0 3.94e-01 85.6% 82.4%
1a36A04 1.10.132.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.67 51.0 4.31e-01 80.8% 54.9%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.67 46.0 4.06e-01 71.2% 83.0%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 45.0 4.69e-01 71.2% 84.5%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.64 47.0 4.67e-01 77.9% 88.2%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 52.0 4.87e-01 87.5% 72.7%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 49.0 3.77e-01 82.7% 97.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.62 44.0 4.42e-01 74.0% 84.1%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 48.0 4.59e-01 85.6% 92.7%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 45.0 4.39e-01 83.7% 93.8%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.56 44.0 3.97e-01 84.6% 84.2%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3377936 3922.1.1.173 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF3493 0.84 58.0 6.40e-01 70.2% 85.9%
3339157 3755.3.1.370 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF632 0.81 57.0 5.57e-01 71.2% 69.1%
3978643 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.81 58.0 3.92e-01 73.1% 38.8%
3707005 3599.1.1.0 alpha superhelices › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain › Mitochondrial malonyl-CoA decarboxylase helical domain 0.81 63.0 5.47e-01 80.8% 62.7%
4167563 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.81 56.0 5.24e-01 71.2% 64.0%
3924136 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.80 62.0 5.31e-01 79.8% 89.7%
5035200 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 52.0 6.04e-01 70.2% 90.7%
3931442 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.80 63.0 4.41e-01 82.7% 75.7%
3922588 3559.1.1.40 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Bap31 0.80 62.0 5.20e-01 80.8% 68.5%
3406932 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.79 54.0 3.72e-01 70.2% 45.7%
4479398 3755.1.1.8 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ 0.79 54.0 4.82e-01 70.2% 80.0%
3505878 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.79 54.0 3.83e-01 70.2% 27.5%
3815712 5086.1.1.15 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Mit_KHE1 0.79 61.0 4.53e-01 79.8% 38.3%
4387171 603.5.1.18 alpha bundles › STAT-like › FlgN-like › FlgN-like › Med30 0.79 55.0 4.74e-01 71.2% 56.8%
3956835 5069.1.1.3 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I 0.79 65.0 4.62e-01 87.5% 73.2%
3402492 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.79 54.0 4.17e-01 70.2% 34.4%
3518474 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.79 52.0 4.81e-01 71.2% 53.8%
3260134 622.4.1.61 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Mit_KHE1 0.78 61.0 5.37e-01 80.8% 66.9%
3247549 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.78 59.0 5.28e-01 78.8% 90.7%
3961790 150.8.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › PPE › PPE › PPE 0.78 54.0 4.96e-01 71.2% 71.5%
3427750 633.21.1.18 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom 0.78 57.0 4.90e-01 76.9% 95.0%
4305317 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.77 54.0 3.18e-01 71.2% 14.1%
4962781 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.77 50.0 5.82e-01 70.2% 92.0%
5072280 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 53.0 4.10e-01 70.2% 34.0%
3927530 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.77 63.0 4.31e-01 85.6% 86.5%
3737954 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.77 63.0 5.46e-01 85.6% 85.3%
3532384 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.77 53.0 3.82e-01 71.2% 30.0%
3564754 604.1.1.96 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31 0.76 59.0 5.37e-01 80.8% 85.2%
5062016 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.76 55.0 5.62e-01 74.0% 79.0%
3503849 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.76 52.0 3.70e-01 70.2% 25.8%
5007128 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 52.0 3.51e-01 70.2% 20.9%
3202568 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.76 69.0 5.67e-01 100.0% 87.0%
3932987 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.75 52.0 3.84e-01 71.2% 27.9%
3945031 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.75 52.0 4.82e-01 71.2% 60.0%
4642325 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.75 52.0 4.82e-01 71.2% 59.2%
4950969 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.75 52.0 3.33e-01 71.2% 15.7%
3988781 604.6.1.63 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF3169 0.75 56.0 5.10e-01 77.9% 79.3%
3612941 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 51.0 4.60e-01 70.2% 83.6%
5058832 141.1.1.3 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.74 60.0 4.27e-01 86.5% 41.0%
3972958 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.74 60.0 4.19e-01 85.6% 88.3%
3633621 192.5.1.16 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › PF26729 0.74 53.0 6.00e-01 75.0% 100.0%
5046100 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.73 59.0 4.16e-01 85.6% 90.3%
3960783 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.72 49.0 5.48e-01 70.2% 91.3%
3949608 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.72 58.0 5.50e-01 86.5% 100.0%
3205388 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 49.0 3.76e-01 71.2% 33.2%
3516023 109.4.1.150 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ufd2P_core 0.71 63.0 3.67e-01 97.1% 22.4%
3981585 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.71 49.0 5.58e-01 71.2% 100.0%
3186506 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.71 54.0 3.59e-01 79.8% 48.2%
5043886 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.71 50.0 4.24e-01 73.1% 48.2%
3239474 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.71 56.0 4.74e-01 83.7% 92.1%
3718408 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.71 64.0 6.28e-01 97.1% 94.5%
3875643 109.4.1.150 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ufd2P_core 0.71 62.0 3.61e-01 95.2% 27.8%
4286404 3755.1.1.14 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › T3SSipB 0.70 51.0 4.30e-01 76.9% 86.1%
3598650 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.70 57.0 5.98e-01 85.6% 93.7%
4333962 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.69 48.0 3.79e-01 71.2% 35.8%
3725145 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.69 55.0 3.71e-01 83.7% 35.8%
3868214 109.4.1.1302 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30363 0.69 58.0 4.95e-01 88.5% 76.2%
3849009 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.69 47.0 3.56e-01 71.2% 33.1%
3935140 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.69 57.0 4.66e-01 87.5% 88.9%
3390311 604.7.1.0 alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.69 56.0 5.55e-01 85.6% 94.5%
3235287 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 56.0 4.03e-01 86.5% 46.1%
3292565 5086.1.1.15 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Mit_KHE1 0.68 53.0 4.85e-01 83.7% 67.9%
3592927 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.68 53.0 4.59e-01 81.7% 94.8%
3443143 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 56.0 4.61e-01 86.5% 71.4%
4501248 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.67 55.0 4.66e-01 87.5% 85.9%
3206406 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.66 49.0 4.22e-01 77.9% 49.1%
3788511 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.66 47.0 3.00e-01 73.1% 57.4%
3788506 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.65 58.0 5.11e-01 97.1% 79.3%
3787103 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.63 51.0 4.61e-01 87.5% 73.6%
3926694 3324.1.1.0 extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases 0.63 49.0 4.38e-01 82.7% 62.8%
3511712 5069.1.3.66 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7TM_GPCR_Srw 0.60 41.0 3.85e-01 71.2% 62.2%
3746208 601.18.1.6 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 0.59 47.0 4.17e-01 87.5% 79.2%