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envelope_protein_UL78

Euk-Vir

Panine_betaherpesvirus_2

envelope_protein_UL78__NP_612711__Panine_betaherpesvirus_2__188763

Identity

Accession:
NP_612711 ↗
Protein ID:
envelope_protein_UL78
Kingdom:
euk

Quality

71.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Panine_betaherpesvirus_2

TaxID: 188763

Cluster

View cluster (110 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 292-340
PDB
Domain cluster: representative
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.92 83.0 6.80e-01 100.0% 60.5%
1ykeD00 6.10.280.10 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator complex, subunit Med21 0.91 84.0 6.21e-01 100.0% 44.2%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.89 68.0 6.27e-01 81.6% 64.5%
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.89 65.0 5.16e-01 77.6% 40.9%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.89 76.0 7.23e-01 100.0% 80.7%
3tklB01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.87 76.0 7.00e-01 98.0% 83.9%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.86 77.0 5.92e-01 100.0% 46.2%
1t7sA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.85 71.0 5.15e-01 100.0% 34.9%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.85 65.0 5.20e-01 81.6% 45.6%
1ucuA01 6.10.280.190 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.85 73.0 6.53e-01 100.0% 69.1%
1skvA00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.84 75.0 6.84e-01 100.0% 81.2%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.84 75.0 6.07e-01 100.0% 53.8%
3k6tB00 1.20.5.4010 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.83 66.0 6.64e-01 100.0% 85.7%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.82 66.0 5.16e-01 89.8% 41.9%
2wmmA01 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.82 63.0 6.30e-01 95.9% 83.7%
4uelA02 1.20.58.860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 70.0 6.18e-01 100.0% 66.7%
1vx7301 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.81 67.0 5.88e-01 100.0% 62.2%
3b2eF00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.81 64.0 5.97e-01 87.8% 100.0%
2kp8A00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.81 70.0 6.19e-01 100.0% 69.4%
3jcuZ00 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.80 70.0 6.56e-01 100.0% 80.3%
3kd3A02 1.10.150.210 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 0.80 55.0 5.13e-01 71.4% 58.3%
1l5jA03 3.40.1060.10 Alpha Beta › 3-Layer(aba) Sandwich › Aconitase; Domain 2 › Aconitase, Domain 2 0.80 61.0 4.14e-01 87.8% 23.7%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.80 69.0 6.40e-01 100.0% 82.8%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.79 69.0 6.52e-01 98.0% 82.8%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.79 66.0 5.97e-01 100.0% 68.6%
2itbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 66.0 4.44e-01 100.0% 25.8%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 57.0 5.49e-01 83.7% 100.0%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.76 62.0 5.31e-01 100.0% 55.4%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.75 64.0 5.01e-01 100.0% 64.9%
2np9A01 1.20.58.1300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 64.0 4.74e-01 100.0% 36.6%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.73 57.0 5.66e-01 93.9% 86.3%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.73 58.0 4.48e-01 100.0% 38.5%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.73 62.0 4.63e-01 98.0% 69.0%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.73 63.0 5.74e-01 100.0% 73.8%
1uddA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.72 59.0 3.92e-01 98.0% 49.3%
4jleA00 6.10.280.180 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium RESA, N-terminal helical domain 0.71 62.0 4.40e-01 98.0% 32.9%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.70 61.0 3.93e-01 100.0% 20.2%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.70 58.0 3.83e-01 100.0% 22.1%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.69 58.0 5.08e-01 100.0% 65.4%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 56.0 5.16e-01 100.0% 69.0%
7ymiD01 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.68 55.0 3.89e-01 100.0% 29.4%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.67 56.0 3.37e-01 100.0% 24.8%
4a4kA01 1.20.1500.20 Mainly Alpha › Up-down Bundle › YheA-like fold › 0.65 54.0 4.24e-01 100.0% 44.2%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.65 51.0 4.47e-01 98.0% 58.8%
4cb8A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.64 52.0 3.04e-01 100.0% 18.0%
3g2bA00 1.10.10.1150 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) 0.64 50.0 4.09e-01 85.7% 60.0%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.63 51.0 4.13e-01 89.8% 75.8%
3k3oA02 1.20.58.1360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 55.0 4.59e-01 98.0% 63.1%
1rsoB00 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.63 51.0 4.98e-01 95.9% 83.9%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3517330 603.2.1.1 ↗ alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.94 87.0 5.53e-01 100.0% 23.3%
5065070 192.15.1.3 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Vps23_core 0.93 77.0 6.85e-01 87.8% 66.2%
3708789 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.92 83.0 6.55e-01 100.0% 51.6%
4316383 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.90 82.0 6.46e-01 100.0% 51.6%
3715476 4323.1.1.1 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.89 82.0 5.62e-01 100.0% 32.7%
3282520 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.89 70.0 6.20e-01 85.7% 60.0%
3741234 605.2.1.3 ↗ alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N 0.89 79.0 5.94e-01 100.0% 45.2%
3241030 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.88 78.0 4.66e-01 100.0% 15.6%
5025813 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.87 77.0 5.91e-01 100.0% 47.3%
3211407 3652.1.1.0 ↗ alpha duplicates or obligate multimers › Qua1 › Qua1 › Qua1 0.86 68.0 6.80e-01 100.0% 84.0%
4937169 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.86 76.0 5.83e-01 100.0% 47.3%
4470267 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.86 76.0 5.84e-01 100.0% 47.3%
3182497 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.86 75.0 4.35e-01 100.0% 21.2%
5030299 633.16.1.0 ↗ alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like 0.86 76.0 6.45e-01 100.0% 61.3%
3839273 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.85 75.0 5.77e-01 100.0% 48.2%
3723174 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.85 76.0 6.57e-01 100.0% 66.7%
3574626 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.85 76.0 5.40e-01 100.0% 35.0%
4120406 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.84 74.0 5.68e-01 100.0% 47.3%
4028291 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.84 75.0 4.33e-01 100.0% 11.9%
5039030 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.84 71.0 6.84e-01 93.9% 83.6%
3168521 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 71.0 4.41e-01 95.9% 18.5%
3355246 192.1.1.0 ↗ alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.83 75.0 6.27e-01 100.0% 63.7%
3676390 3559.1.1.0 ↗ a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 0.81 71.0 5.34e-01 100.0% 40.8%
3169645 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 68.0 3.89e-01 100.0% 9.5%
3201946 3718.1.1.8 ↗ alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › Fung_rhodopsin 0.80 68.0 5.31e-01 100.0% 44.5%
3276289 4106.1.1.1 ↗ few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.80 69.0 4.48e-01 100.0% 21.8%
5006936 605.1.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.80 67.0 6.23e-01 100.0% 75.4%
4994340 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.77 69.0 4.93e-01 100.0% 36.4%
3700089 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.75 62.0 5.79e-01 100.0% 75.4%
4353 605.4.1.1 ↗ alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › Rop 0.73 61.0 5.82e-01 98.0% 84.7%
3283655 3812.1.1.0 ↗ alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE 0.71 56.0 5.62e-01 100.0% 88.0%
5023515 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.71 60.0 3.59e-01 100.0% 14.0%
3928221 4.1.1.310 ↗ beta barrels › SH3 › SH3 › SH3 › PF26050 0.68 59.0 4.27e-01 100.0% 37.1%
D2 medium residues 63-196
PDB
Domain cluster: rep: GP78__YP_007417844__Caviid_betaherpesvirus_2__33706__D64-182
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25707.2 best UL78 220.7 4.90e-65 100.0% 35.9%
D3 medium residues 197-283
PDB
Domain cluster: rep: GP78__YP_007417844__Caviid_betaherpesvirus_2__33706__D183-287
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25707.2 best UL78 130.9 9.50e-38 100.0% 23.4%