←Back to structures
envelope_protein_UL78
Euk-VirSaimiriine_betaherpesvirus_4
envelope_protein_UL78__YP_004940241__Saimiriine_betaherpesvirus_4__1535247
Identity
- Accession:
- YP_004940241 ↗
- Protein ID:
- envelope_protein_UL78
- Kingdom:
- euk
Quality
78.0
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Saimiriine_betaherpesvirus_4
TaxID: 1535247
Cluster
View cluster (110 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 41-162
Domain cluster:
rep: GP78__YP_007417844__Caviid_betaherpesvirus_2__33706__D64-182
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25707.2 best | UL78 | 195.6 | 2.10e-57 | 100.0% | 32.9% |
| PF00001.27 | 7tm_1 | 41.2 | 2.00e-10 | 98.4% | 41.9% |
D2
medium
residues 163-268
Domain cluster:
rep: GP78__YP_007417844__Caviid_betaherpesvirus_2__33706__D183-287
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF25707.2 best | UL78 | 170.0 | 1.20e-49 | 100.0% | 28.6% |
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5unhA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.86 | 80.0 | 5.76e-01 | 100.0% | 41.1% |
| 3emlA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.77 | 70.0 | 5.07e-01 | 100.0% | 37.8% |
| 3uonA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.75 | 69.0 | 4.99e-01 | 100.0% | 38.0% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 66.0 | 4.83e-01 | 96.2% | 41.5% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 68.0 | 4.95e-01 | 100.0% | 38.6% |
| 6c1qB02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.73 | 67.0 | 4.85e-01 | 100.0% | 42.7% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.72 | 61.0 | 4.32e-01 | 92.5% | 69.5% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 55.0 | 5.02e-01 | 100.0% | 62.2% |
| 3lssA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.70 | 53.0 | 5.24e-01 | 80.2% | 88.4% |
| 1st6A04 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.68 | 54.0 | 5.24e-01 | 100.0% | 77.8% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 47.0 | 4.57e-01 | 71.7% | 87.4% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.67 | 55.0 | 5.30e-01 | 100.0% | 78.2% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.66 | 59.0 | 5.01e-01 | 100.0% | 59.0% |
| 3t9oB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.66 | 57.0 | 5.45e-01 | 98.1% | 81.7% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 46.0 | 4.07e-01 | 72.6% | 48.4% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 54.0 | 5.07e-01 | 100.0% | 73.4% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.65 | 55.0 | 4.06e-01 | 91.5% | 63.8% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 53.0 | 5.34e-01 | 100.0% | 90.4% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 51.0 | 4.77e-01 | 100.0% | 70.1% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 55.0 | 4.19e-01 | 100.0% | 79.6% |
| 4iggB02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 50.0 | 4.82e-01 | 100.0% | 75.2% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 49.0 | 4.00e-01 | 98.1% | 43.4% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.63 | 56.0 | 5.15e-01 | 100.0% | 78.3% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 54.0 | 5.20e-01 | 100.0% | 84.0% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 46.0 | 3.70e-01 | 80.2% | 41.3% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 50.0 | 5.04e-01 | 86.8% | 97.2% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.61 | 48.0 | 4.70e-01 | 100.0% | 76.7% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 53.0 | 4.21e-01 | 99.1% | 46.2% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 46.0 | 4.54e-01 | 79.2% | 77.7% |
| 3geeA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.60 | 49.0 | 4.26e-01 | 99.1% | 56.5% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 45.0 | 4.40e-01 | 79.2% | 77.8% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.60 | 52.0 | 5.32e-01 | 99.1% | 100.0% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.58 | 51.0 | 4.82e-01 | 97.2% | 85.6% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.57 | 47.0 | 3.89e-01 | 87.7% | 69.4% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 50.0 | 4.44e-01 | 100.0% | 87.3% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 45.0 | 4.60e-01 | 100.0% | 95.1% |
| 1kf6D00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 45.0 | 4.39e-01 | 99.1% | 93.3% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.51 | 39.0 | 3.85e-01 | 82.1% | 78.4% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.51 | 36.0 | 3.97e-01 | 96.2% | 96.3% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3920828 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.81 | 75.0 | 4.97e-01 | 100.0% | 50.9% |
| 3899412 | 5069.1.3.67 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7tm_1 | 0.79 | 72.0 | 6.82e-01 | 99.1% | 92.0% |
| 3994087 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.78 | 71.0 | 5.30e-01 | 98.1% | 56.4% |
| 3917696 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.76 | 68.0 | 5.47e-01 | 98.1% | 58.0% |
| 4018124 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.73 | 66.0 | 5.08e-01 | 100.0% | 76.7% |
| 3441289 | 3684.1.1.19 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF1110 | 0.73 | 65.0 | 5.55e-01 | 100.0% | 76.0% |
| 4273807 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.73 | 50.0 | 3.30e-01 | 71.7% | 44.8% |
| 5008556 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.72 | 46.0 | 5.03e-01 | 92.5% | 80.0% |
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.72 | 60.0 | 5.53e-01 | 100.0% | 70.0% |
| 3775030 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.71 | 64.0 | 4.55e-01 | 100.0% | 40.3% |
| 3932745 | 5001.1.1.44 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv | 0.71 | 62.0 | 4.46e-01 | 100.0% | 33.3% |
| 3316275 | 601.4.1.55 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DUF7795 | 0.71 | 62.0 | 5.49e-01 | 97.2% | 66.0% |
| 3730449 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.71 | 64.0 | 4.83e-01 | 100.0% | 72.4% |
| 3398752 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.70 | 64.0 | 4.41e-01 | 100.0% | 67.7% |
| 3740499 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.69 | 62.0 | 4.87e-01 | 100.0% | 80.9% |
| 3734743 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.69 | 61.0 | 4.72e-01 | 100.0% | 70.8% |
| 3419627 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.69 | 60.0 | 5.38e-01 | 100.0% | 68.0% |
| 3592587 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.69 | 48.0 | 4.59e-01 | 72.6% | 62.4% |
| 3573786 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.68 | 57.0 | 4.61e-01 | 96.2% | 48.0% |
| 3880737 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.68 | 61.0 | 5.08e-01 | 100.0% | 61.6% |
| 3494774 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 60.0 | 5.16e-01 | 100.0% | 67.1% |
| 4037845 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.67 | 59.0 | 5.74e-01 | 98.1% | 96.5% |
| 3727661 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.66 | 59.0 | 5.35e-01 | 100.0% | 74.5% |
| 4541195 | 3755.3.1.470 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T3SSipB | 0.66 | 54.0 | 5.09e-01 | 89.6% | 96.2% |
| 5073511 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.66 | 60.0 | 5.09e-01 | 100.0% | 70.0% |
| 3241470 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.65 | 55.0 | 3.19e-01 | 91.5% | 26.7% |
| 3214379 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.64 | 58.0 | 3.52e-01 | 100.0% | 70.7% |
| 4970712 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.64 | 56.0 | 5.65e-01 | 97.2% | 97.1% |
| 1144608 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.64 | 46.0 | 4.53e-01 | 75.5% | 73.7% |
| 3511712 | 5069.1.3.66 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7TM_GPCR_Srw | 0.63 | 57.0 | 5.27e-01 | 100.0% | 86.7% |
| 4988447 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.63 | 55.0 | 5.42e-01 | 100.0% | 92.2% |
| 4424778 | 605.2.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N | 0.63 | 48.0 | 4.83e-01 | 83.0% | 90.0% |
| 4175087 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.63 | 48.0 | 4.83e-01 | 83.0% | 89.1% |
| 3851394 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.62 | 49.0 | 4.61e-01 | 99.1% | 70.0% |
| 3924789 | 1025.1.1.0 ↗ | alpha bundles › Stonustoxin helical domain › Stonustoxin helical domain › Stonustoxin helical domain | 0.61 | 54.0 | 4.86e-01 | 100.0% | 74.0% |
| 3573035 | 109.4.1.3370 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PL48 | 0.60 | 47.0 | 4.45e-01 | 87.7% | 98.5% |
| 3766950 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.60 | 48.0 | 4.40e-01 | 100.0% | 64.1% |
| 3488340 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.58 | 49.0 | 4.84e-01 | 100.0% | 86.1% |
| 3536154 | 5001.1.1.118 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1, 7TM_GPCR_Srbc | 0.55 | 48.0 | 3.37e-01 | 97.2% | 30.3% |
D3
medium
residues 273-301