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evelope_glycoprotein_H
Euk-VirAteline_alphaherpesvirus_1
evelope_glycoprotein_H__YP_009361916__Ateline_alphaherpesvirus_1__35243
Identity
- Accession:
- YP_009361916 ↗
- Protein ID:
- evelope_glycoprotein_H
- Kingdom:
- euk
Quality
75.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Simplexvirus›
Ateline_alphaherpesvirus_1
TaxID: 35243
Cluster
View cluster (30 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 37-106
D2
medium
residues 125-173_218-343_373-389
D3
medium
residues 174-217_344-372_390-416_440-475
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ro3A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 31.0 | 3.00e-01 | 89.7% | 50.3% |
| 4g09A03 | 1.20.5.1300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.50 | 21.0 | 3.02e-01 | 87.5% | 89.1% |
D4
medium
residues 476-594
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 59.0 | 5.40e-01 | 89.1% | 74.7% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.69 | 48.0 | 4.89e-01 | 71.4% | 82.1% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.68 | 48.0 | 4.23e-01 | 72.3% | 56.0% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 41.0 | 4.41e-01 | 72.3% | 69.6% |
| 8amzT01 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 52.0 | 3.97e-01 | 86.6% | 36.7% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 47.0 | 5.17e-01 | 72.3% | 92.5% |
| 3cqcB01 | 1.20.58.1380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 45.0 | 5.10e-01 | 99.2% | 98.9% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.63 | 39.0 | 4.18e-01 | 72.3% | 72.7% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.62 | 43.0 | 4.22e-01 | 70.6% | 75.2% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 44.0 | 4.17e-01 | 80.7% | 61.1% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.60 | 45.0 | 4.59e-01 | 84.9% | 82.5% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.58 | 44.0 | 4.24e-01 | 80.7% | 84.9% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.56 | 38.0 | 3.95e-01 | 84.9% | 74.3% |
| 3gi8C00 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.53 | 45.0 | 3.09e-01 | 92.4% | 89.9% |
| 4i4cB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 45.0 | 3.21e-01 | 100.0% | 86.9% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3509826 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.74 | 53.0 | 5.19e-01 | 73.9% | 90.8% |
| 3794795 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.73 | 50.0 | 5.40e-01 | 70.6% | 94.0% |
| 3481781 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.73 | 46.0 | 5.40e-01 | 71.4% | 93.8% |
| 3687894 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.72 | 60.0 | 3.90e-01 | 89.1% | 21.0% |
| 3969668 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.65 | 45.0 | 3.69e-01 | 71.4% | 81.3% |
| 3991875 | 604.13.1.0 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like | 0.65 | 49.0 | 5.13e-01 | 88.2% | 87.3% |
| 3371542 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 43.0 | 3.93e-01 | 89.9% | 50.0% |
| 3796589 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.64 | 47.0 | 5.07e-01 | 86.6% | 91.0% |
| 3497415 | 109.4.1.292 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3a_PCI_TPR-like | 0.61 | 48.0 | 3.31e-01 | 85.7% | 24.5% |
| 3593023 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 46.0 | 3.44e-01 | 89.1% | 30.5% |
| 3776919 | 109.4.1.1749 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_ECM29 | 0.59 | 48.0 | 4.01e-01 | 89.1% | 52.7% |
| 4016562 | 109.4.1.143 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ric8 | 0.59 | 49.0 | 3.34e-01 | 95.8% | 23.0% |
| 3456183 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 42.0 | 4.53e-01 | 83.2% | 94.0% |
| 3624667 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.56 | 48.0 | 3.57e-01 | 94.1% | 81.9% |
| 5039732 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.56 | 39.0 | 4.02e-01 | 72.3% | 93.8% |
| 3713949 | 109.6.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N | 0.55 | 45.0 | 3.45e-01 | 89.1% | 49.3% |
| None | — | 0.52 | 46.0 | 3.24e-01 | 100.0% | 82.4% | |
| 3612510 | 171.1.1.0 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like | 0.52 | 40.0 | 3.17e-01 | 83.2% | 62.7% |
| 3231735 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.51 | 41.0 | 3.61e-01 | 85.7% | 82.7% |
| 3937339 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.51 | 40.0 | 3.60e-01 | 83.2% | 82.4% |
| 3619928 | 189.1.1.3 ↗ | alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › Plexin_cytopl | 0.51 | 44.0 | 3.03e-01 | 96.6% | 47.0% |
| 5042141 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.51 | 45.0 | 3.30e-01 | 100.0% | 46.7% |
| 3518148 | 189.1.1.3 ↗ | alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › Plexin_cytopl | 0.51 | 44.0 | 3.03e-01 | 96.6% | 80.0% |
| 3592552 | 171.1.1.0 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like | 0.50 | 39.0 | 3.24e-01 | 82.4% | 63.3% |
D5
medium
residues 595-670
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3f1xA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.62 | 46.0 | 3.69e-01 | 78.9% | 86.6% |
| 2jdiH02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.61 | 29.0 | 3.91e-01 | 75.0% | 85.7% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.60 | 42.0 | 4.62e-01 | 80.3% | 90.2% |
| 1irxA04 | 1.10.10.770 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.58 | 44.0 | 3.96e-01 | 81.6% | 93.5% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 41.0 | 3.57e-01 | 75.0% | 65.5% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.57 | 44.0 | 4.07e-01 | 82.9% | 71.1% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.56 | 48.0 | 3.57e-01 | 96.1% | 81.5% |
| 2e5yA02 | 1.20.5.440 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › ATP synthase delta/epsilon subunit, C-terminal domain | 0.56 | 33.0 | 4.19e-01 | 75.0% | 100.0% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.56 | 40.0 | 3.87e-01 | 75.0% | 78.8% |
| 2b3tB01 | 6.10.140.1980 | Special › Helix non-globular › Helix Hairpins › | 0.55 | 34.0 | 3.65e-01 | 81.6% | 72.3% |
| 4qhpA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.55 | 45.0 | 3.02e-01 | 92.1% | 23.2% |
| 1vp7A00 | 1.10.287.1040 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit | 0.55 | 41.0 | 4.26e-01 | 89.5% | 88.2% |
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 38.0 | 3.48e-01 | 76.3% | 56.7% |
| 1ma1A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.53 | 37.0 | 3.96e-01 | 82.9% | 85.9% |
| 4iw9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 41.0 | 3.62e-01 | 85.5% | 78.8% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.52 | 41.0 | 3.54e-01 | 85.5% | 55.0% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3782284 | 223.2.1.0 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like | 0.62 | 44.0 | 3.30e-01 | 76.3% | 38.6% |
| 3783474 | 604.12.1.71 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › TMD_POM152 | 0.61 | 44.0 | 3.89e-01 | 76.3% | 71.3% |
| 3173138 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.61 | 43.0 | 4.16e-01 | 76.3% | 72.2% |
| 4036838 | 192.6.1.1 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE | 0.60 | 35.0 | 4.31e-01 | 75.0% | 90.0% |
| 3935633 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.60 | 46.0 | 3.43e-01 | 81.6% | 46.5% |
| 3777869 | 192.13.1.2 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like › Nexin_C | 0.59 | 45.0 | 3.86e-01 | 81.6% | 57.5% |
| 143026 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.57 | 47.0 | 3.47e-01 | 97.4% | 82.5% |
| 5032045 | 4163.1.1.0 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like | 0.56 | 44.0 | 4.03e-01 | 85.5% | 94.0% |
| 4176828 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.56 | 40.0 | 4.19e-01 | 80.3% | 82.9% |
| 4075864 | 192.6.1.0 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain | 0.55 | 38.0 | 4.30e-01 | 72.4% | 98.2% |
| 4013672 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.53 | 39.0 | 3.62e-01 | 80.3% | 62.0% |
| 3308779 | 4982.1.1.3 ↗ | alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain › Tic110 | 0.50 | 40.0 | 3.27e-01 | 86.8% | 58.6% |
D6
medium
residues 671-813
Domain cluster:
rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF17488.8 best | Herpes_glycoH_C | 46.0 | 6.00e-12 | 95.1% | 90.8% |