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fusion_protein
Euk-VirAvian_orthoavulavirus_1
fusion_protein__YP_009513197__Avian_orthoavulavirus_1__2560319
Identity
- Accession:
- YP_009513197 ↗
- Protein ID:
- fusion_protein
- Kingdom:
- euk
Quality
70.6
mean pLDDT
Taxonomy
Orthornavirae›
Negarnaviricota›
Monjiviricetes›
Mononegavirales›
Paramyxoviridae›
Orthoavulavirus›
avian_paramyxovirus_1
TaxID: 2560319
Cluster
View cluster (59 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 37-47_293-366
Domain cluster:
rep: fusion_protein__YP_338081__J-virus__322067__D282-298_311-354
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 57.1 | 1.50e-15 | 91.8% | 15.0% |
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1g5gA01 | 2.40.490.10 | Mainly Beta › Beta Barrel › Head and neck region of the ectodomain of NDV fusion glycoprotein › Newcastle disease virus like domain | 0.96 | 93.0 | 8.34e-01 | 100.0% | 86.4% |
| 2b9bA01 | 2.40.490.10 | Mainly Beta › Beta Barrel › Head and neck region of the ectodomain of NDV fusion glycoprotein › Newcastle disease virus like domain | 0.94 | 90.0 | 7.96e-01 | 100.0% | 77.2% |
| 1ztmA01 | 2.40.490.10 | Mainly Beta › Beta Barrel › Head and neck region of the ectodomain of NDV fusion glycoprotein › Newcastle disease virus like domain | 0.89 | 84.0 | 7.64e-01 | 100.0% | 82.4% |
| 3sluA02 | 3.10.450.350 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.57 | 35.0 | 2.98e-01 | 92.9% | 37.2% |
| 1g3pA02 | 3.90.450.1 | Alpha Beta › Alpha-Beta Complex › Minor Coat Protein; domain 2 › Minor Coat Protein; Domain 2 | 0.57 | 38.0 | 3.56e-01 | 87.1% | 55.8% |
| 2y3vD00 | 2.170.210.20 | Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › Spindle assembly abnormal protein 6, N-terminal domain | 0.55 | 47.0 | 3.91e-01 | 95.3% | 100.0% |
| 4r80A00 | 3.10.450.630 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 35.0 | 3.69e-01 | 87.1% | 71.1% |
| 2g30A02 | 3.30.310.10 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein | 0.55 | 42.0 | 3.82e-01 | 100.0% | 60.3% |
| 4p78C00 | 3.30.920.30 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Hypothetical protein. | 0.54 | 35.0 | 3.89e-01 | 100.0% | 86.4% |
| 2f5kA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.53 | 30.0 | 3.80e-01 | 98.8% | 96.0% |
| 7r97A02 | 3.30.160.20 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.52 | 29.0 | 3.22e-01 | 92.9% | 67.6% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1738158 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.95 | 91.0 | 5.80e-01 | 100.0% | 95.6% |
| 4873341 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.95 | 90.0 | 5.82e-01 | 100.0% | 93.5% |
| 1175806 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.95 | 79.0 | 5.20e-01 | 87.1% | 25.1% |
| 4871079 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.92 | 87.0 | 5.71e-01 | 100.0% | 93.4% |
| 4881664 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.91 | 76.0 | 5.14e-01 | 87.1% | 28.0% |
| 1737404 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.90 | 85.0 | 5.47e-01 | 100.0% | 93.4% |
| 4872787 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.89 | 74.0 | 5.02e-01 | 87.1% | 28.1% |
| 4871594 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.87 | 71.0 | 4.63e-01 | 87.1% | 21.8% |
| 4884487 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.87 | 71.0 | 4.59e-01 | 87.1% | 21.3% |
| 3237142 | 5093.1.1.0 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein | 0.64 | 56.0 | 3.76e-01 | 98.8% | 78.5% |
| 3822993 | 5.1.3.160 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_KLHDC2_KLHL20_DRC7, Beta-prop_ATRN-LZTR1 | 0.61 | 46.0 | 3.00e-01 | 81.2% | 35.5% |
| 3268410 | 5.1.3.135 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Kelch_KLHDC2_KLHL20_DRC7, Beta-prop_ATRN-LZTR1 | 0.60 | 46.0 | 3.03e-01 | 82.4% | 43.5% |
| 4953814 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.59 | 34.0 | 3.96e-01 | 91.8% | 80.0% |
| 3895069 | 5.1.8.4 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › putative conserved lipoprotein NT01CX_1156 › Kelch_KLHDC2_KLHL20_DRC7 | 0.57 | 42.0 | 3.40e-01 | 80.0% | 56.0% |
| 3802860 | 5.1.4.550 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Kelch_FKB95 | 0.56 | 42.0 | 2.91e-01 | 82.4% | 40.9% |
| 3915618 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 41.0 | 2.45e-01 | 82.4% | 21.8% |
| 3599562 | 292.2.1.0 ↗ | a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain | 0.53 | 36.0 | 3.66e-01 | 100.0% | 70.6% |
| 3829563 | 897.1.1.0 ↗ | a+b two layers › Acidic mitochondrial matrix protein p32-like › Acidic mitochondrial matrix protein p32 › Acidic mitochondrial matrix protein p32 | 0.51 | 45.0 | 3.65e-01 | 98.8% | 63.0% |
| 4982246 | 3521.1.1.0 ↗ | a+b three layers › Polymerase basic protein 2 cap-binding domain › Polymerase basic protein 2 cap-binding domain › Polymerase basic protein 2 cap-binding domain | 0.51 | 42.0 | 3.99e-01 | 100.0% | 77.0% |
| 2714027 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.50 | 38.0 | 2.68e-01 | 80.0% | 53.9% |
D2
medium
residues 59-105_135-170_197-228
Domain cluster:
rep: fusion__NP_047111__Hendra_henipavirus__63330__D69-104_123-148_178-225
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 37.8 | 1.10e-09 | 41.7% | 9.2% |
| PF00523.24 | Fusion_gly | 33.0 | 3.00e-08 | 33.9% | 7.6% |
D3
medium
residues 229-292
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 54.4 | 1.00e-14 | 100.0% | 12.7% |
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1g5gA02 | 1.10.287.2480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 64.0 | 4.60e-01 | 96.9% | 72.9% |
| 2joqA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.62 | 38.0 | 3.65e-01 | 82.8% | 52.0% |
| 2v4jA02 | 3.30.70.2500 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 36.0 | 3.11e-01 | 100.0% | 37.6% |
| 4lecA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 44.0 | 3.06e-01 | 79.7% | 35.1% |
| 6wimA02 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.56 | 34.0 | 3.27e-01 | 90.6% | 51.4% |
| 2r7dA03 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.54 | 45.0 | 4.62e-01 | 96.9% | 100.0% |
| 2k5iA01 | 2.30.30.90 | Mainly Beta › Roll › SH3 type barrels. › Ferrous iron transport protein A (FeoA) | 0.51 | 36.0 | 3.38e-01 | 98.4% | 58.3% |
| 4lwoB02 | 2.70.160.11 | Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 | 0.50 | 42.0 | 3.17e-01 | 100.0% | 77.2% |
| 4wiwA02 | 3.10.50.10 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.50 | 30.0 | 2.99e-01 | 100.0% | 53.6% |
| 1tvzA01 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.50 | 39.0 | 2.76e-01 | 90.6% | 37.5% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4872787 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.83 | 75.0 | 4.89e-01 | 100.0% | 24.3% |
| 5043942 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.79 | 43.0 | 4.05e-01 | 100.0% | 45.3% |
| 3253762 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.76 | 41.0 | 3.81e-01 | 93.8% | 42.5% |
| 1737404 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.75 | 63.0 | 3.96e-01 | 100.0% | 17.9% |
| 1175806 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.75 | 66.0 | 4.23e-01 | 100.0% | 21.4% |
| 4881664 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.75 | 66.0 | 4.34e-01 | 100.0% | 23.6% |
| 3315096 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.70 | 38.0 | 4.79e-01 | 92.2% | 97.1% |
| 4776457 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.69 | 61.0 | 5.66e-01 | 98.4% | 81.5% |
| 4871079 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.69 | 61.0 | 3.94e-01 | 100.0% | 21.7% |
| 3429282 | 9.13.1.1 ↗ | beta barrels › Lipocalins/Streptavidin › AOC barrel-like › AOC barrel-like › Dirigent | 0.63 | 42.0 | 3.61e-01 | 98.4% | 41.3% |
| 3625370 | 2003.1.5.73 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 | 0.58 | 44.0 | 2.95e-01 | 79.7% | 29.8% |
| 3229770 | 70.3.1.13 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like › SET_TTL | 0.58 | 44.0 | 3.13e-01 | 84.4% | 80.5% |
| 5045911 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 41.0 | 3.57e-01 | 78.1% | 63.8% |
| 3608673 | 109.4.1.194 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 | 0.56 | 47.0 | 3.02e-01 | 98.4% | 36.2% |
| 4927356 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.56 | 44.0 | 3.87e-01 | 92.2% | 81.9% |
| 3790689 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.55 | 45.0 | 4.42e-01 | 100.0% | 98.6% |
| 4045981 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.54 | 47.0 | 4.23e-01 | 98.4% | 92.2% |
| 3741318 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.51 | 42.0 | 2.63e-01 | 96.9% | 24.3% |
| 3999808 | 389.2.1.3 ↗ | few secondary structure elements › EGF-like › Serine protease inhibitors › Serine protease inhibitors › TIL_2 | 0.51 | 32.0 | 3.70e-01 | 95.3% | 93.3% |
D4
medium
residues 367-475
Domain cluster:
rep: fusion_protein__NP_958053__Mossman_virus__241630__D22-40_355-452
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 115.4 | 3.10e-33 | 100.0% | 22.2% |