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fusion_protein
Euk-VirJ-virus
fusion_protein__YP_338081__J-virus__322067
Identity
- Accession:
- YP_338081 ↗
- Protein ID:
- fusion_protein
- Kingdom:
- euk
Quality
72.8
mean pLDDT
Taxonomy
Orthornavirae›
Negarnaviricota›
Monjiviricetes›
Mononegavirales›
Paramyxoviridae›
Jeilongvirus›
J_virus
TaxID: 322067
Cluster
View cluster (59 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 22-40_299-310_355-464
Domain cluster:
rep: fusion_protein__YP_009094032__Sosuga_virus__1452514__D18-37_283-450
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 89.0 | 3.30e-25 | 87.9% | 23.6% |
D2
medium
residues 41-96_119-171_243-281
Domain cluster:
rep: fusion_protein__BAV03983__Avian_paramyxovirus_goose_Shimane_67_2000__1401445__D50-98_121-280
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 64.2 | 1.00e-17 | 39.9% | 11.3% |
| PF00523.24 | Fusion_gly | 43.9 | 1.50e-11 | 38.5% | 11.5% |
| PF00523.24 | Fusion_gly | 30.9 | 1.30e-07 | 31.1% | 8.8% |
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2joqA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.67 | 23.0 | 3.33e-01 | 98.0% | 65.3% |
| 2wmfA03 | 2.60.220.10 | Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal | 0.64 | 24.0 | 2.67e-01 | 99.3% | 40.5% |
| 1kcvL02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.63 | 25.0 | 3.01e-01 | 98.6% | 51.5% |
| 4k59A00 | 2.60.40.4380 | Mainly Beta › Sandwich › Immunoglobulin-like › Translational regulator CsrA | 0.62 | 25.0 | 3.73e-01 | 97.3% | 84.8% |
| 1ztmA02 | 1.10.287.2480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 58.0 | 5.10e-01 | 98.0% | 98.0% |
| 4d6gA03 | 2.60.220.10 | Mainly Beta › Sandwich › Chondroitinase Ac; Chain A, domain 3 › Polysaccharide lyase family 8-like, C-terminal | 0.60 | 24.0 | 2.59e-01 | 100.0% | 40.8% |
| 1g5gA02 | 1.10.287.2480 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 55.0 | 5.19e-01 | 96.6% | 100.0% |
| 6hhnA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 25.0 | 3.16e-01 | 96.6% | 64.1% |
| 1x8dA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 25.0 | 3.08e-01 | 96.6% | 60.8% |
| 3b82A06 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 21.0 | 2.28e-01 | 100.0% | 36.4% |
| 2f5gA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.55 | 26.0 | 2.83e-01 | 99.3% | 50.0% |
| 2khdA00 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 21.0 | 2.52e-01 | 91.2% | 53.7% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4871594 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.84 | 76.0 | 5.68e-01 | 95.9% | 65.5% |
| 1737404 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.82 | 78.0 | 5.81e-01 | 100.0% | 66.6% |
| 1738158 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.81 | 76.0 | 5.68e-01 | 100.0% | 69.2% |
| 4873341 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.76 | 72.0 | 5.43e-01 | 100.0% | 65.8% |
| 5377 | 304.52.1.1 ↗ | a+b two layers › Alpha-beta plaits › YbeD/HP0495-like › YbeD/HP0495-like › DUF493 | 0.65 | 24.0 | 3.16e-01 | 98.6% | 59.3% |
| 3387300 | 304.52.1.1 ↗ | a+b two layers › Alpha-beta plaits › YbeD/HP0495-like › YbeD/HP0495-like › DUF493 | 0.64 | 23.0 | 3.19e-01 | 98.6% | 63.7% |
| 4871079 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.60 | 57.0 | 4.36e-01 | 100.0% | 63.8% |
| 4941715 | 304.57.1.1 ↗ | a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 | 0.58 | 26.0 | 2.92e-01 | 98.6% | 52.4% |
| 3537609 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.57 | 30.0 | 3.44e-01 | 97.3% | 67.0% |
| 2901051 | 304.6.1.3 ↗ | a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE | 0.56 | 29.0 | 3.64e-01 | 97.3% | 81.8% |
| 3763545 | 304.47.1.0 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain | 0.56 | 30.0 | 3.40e-01 | 97.3% | 67.0% |
| 3763542 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.56 | 30.0 | 3.43e-01 | 97.3% | 70.0% |
| 3374317 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.55 | 27.0 | 3.28e-01 | 100.0% | 70.5% |
| 4177452 | 304.57.1.1 ↗ | a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 | 0.55 | 27.0 | 3.15e-01 | 100.0% | 63.6% |
| 3800751 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.52 | 23.0 | 2.87e-01 | 96.6% | 64.4% |
| 3362546 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.52 | 22.0 | 2.72e-01 | 98.6% | 60.0% |
D3
medium
residues 172-242
Domain cluster:
rep: fusion_protein__YP_009094158__Avian_metaavulavirus_5__2560315__D177-238
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00523.24 best | Fusion_gly | 87.9 | 6.80e-25 | 100.0% | 14.4% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3v9rA00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.54 | 46.0 | 4.30e-01 | 95.8% | 86.4% |
| 4wv4B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.54 | 43.0 | 3.99e-01 | 90.1% | 74.2% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4871594 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.86 | 79.0 | 4.94e-01 | 100.0% | 22.4% |
| 4560457 | 2007.1.14.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › ZnuA | 0.60 | 49.0 | 3.51e-01 | 90.1% | 39.5% |
| 5046133 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 48.0 | 4.46e-01 | 87.3% | 68.9% |
| 3722689 | 148.1.1.12 ↗ | alpha arrays › Histone-like › Histone-related › Histone › Bromo_TP | 0.59 | 48.0 | 4.10e-01 | 90.1% | 83.3% |
| 3573605 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 47.0 | 3.57e-01 | 88.7% | 41.1% |
| 4955753 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.53 | 43.0 | 3.42e-01 | 91.5% | 45.8% |
D4
medium
residues 282-298_311-354
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1g5gA01 | 2.40.490.10 | Mainly Beta › Beta Barrel › Head and neck region of the ectodomain of NDV fusion glycoprotein › Newcastle disease virus like domain | 0.92 | 85.0 | 6.80e-01 | 100.0% | 66.4% |
| 2b9bA01 | 2.40.490.10 | Mainly Beta › Beta Barrel › Head and neck region of the ectodomain of NDV fusion glycoprotein › Newcastle disease virus like domain | 0.91 | 82.0 | 6.48e-01 | 96.7% | 63.2% |
| 1ztmA01 | 2.40.490.10 | Mainly Beta › Beta Barrel › Head and neck region of the ectodomain of NDV fusion glycoprotein › Newcastle disease virus like domain | 0.89 | 82.0 | 6.62e-01 | 98.4% | 66.7% |
| 1iv8A02 | 3.30.1590.10 | Alpha Beta › 2-Layer Sandwich › Maltooligosyl trehalose synthase, domain 2 › Maltooligosyl trehalose synthase, domain 2 | 0.61 | 43.0 | 3.47e-01 | 80.3% | 38.1% |
| 1g3pA01 | 2.30.27.10 | Mainly Beta › Roll › Phage FD Coat Protein, Membrane penetration domain › Phage FD Coat Protein,Membrane penetration domain | 0.57 | 43.0 | 3.90e-01 | 96.7% | 58.0% |
| 4bg7A00 | 2.30.31.10 | Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A | 0.56 | 45.0 | 3.85e-01 | 88.5% | 63.3% |
| 2zu2A01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.54 | 40.0 | 3.46e-01 | 80.3% | 81.6% |
| 2rf4E02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.53 | 41.0 | 3.85e-01 | 90.2% | 86.7% |
| 3bs1A00 | 2.40.50.1020 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › LytTr DNA-binding domain | 0.53 | 35.0 | 3.06e-01 | 70.5% | 65.0% |
| 1p49A03 | 3.30.1120.10 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.53 | 44.0 | 3.71e-01 | 95.1% | 73.1% |
| 2mlkA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 34.0 | 2.90e-01 | 70.5% | 65.5% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1737404 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.97 | 93.0 | 5.56e-01 | 100.0% | 21.8% |
| 4871079 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.97 | 92.0 | 5.62e-01 | 100.0% | 24.0% |
| 4884487 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.96 | 90.0 | 5.40e-01 | 100.0% | 21.0% |
| 4873341 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.94 | 89.0 | 5.37e-01 | 100.0% | 22.5% |
| 4871594 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.94 | 88.0 | 5.30e-01 | 100.0% | 21.5% |
| 1175806 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.93 | 87.0 | 5.37e-01 | 100.0% | 24.7% |
| 4872787 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.93 | 87.0 | 5.49e-01 | 100.0% | 27.8% |
| 1738158 | 5093.1.1.1 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Fusion_gly | 0.93 | 86.0 | 5.19e-01 | 100.0% | 21.4% |
| 4881664 | 11.40.1.1 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-like domain in paramyxoviruses fusion protein › Immunoglobulin-like domain in paramyxoviruses fusion protein › Fusion_gly | 0.90 | 84.0 | 5.27e-01 | 100.0% | 27.7% |
| 3237142 | 5093.1.1.0 ↗ | a+b complex topology › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein › Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein | 0.62 | 53.0 | 3.37e-01 | 100.0% | 21.5% |
| 4797336 | 2004.1.1.23 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom | 0.55 | 32.0 | 2.18e-01 | 77.0% | 13.1% |
| 1099000 | 1.1.5.19 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_C30 | 0.53 | 40.0 | 2.88e-01 | 82.0% | 42.2% |
| 3800005 | 59.1.1.2 ↗ | beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like › RNA_pol_Rpc4 | 0.53 | 42.0 | 3.68e-01 | 86.9% | 77.8% |
| 3590110 | 331.1.1.7 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › Rol_Rep_N | 0.51 | 34.0 | 2.93e-01 | 90.2% | 41.0% |
| 3932822 | 1.1.1.27 ↗ | beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp, TAXi_N | 0.50 | 38.0 | 2.46e-01 | 90.2% | 38.3% |