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glycoprotein_H

Euk-Vir

Cricetid_gammaherpesvirus_2

glycoprotein_H__YP_004207858__Cricetid_gammaherpesvirus_2__1605972

Identity

Accession:
YP_004207858 ↗
Protein ID:
glycoprotein_H
Kingdom:
euk

Quality

80.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Cricetid_gammaherpesvirus_2

TaxID: 1605972

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-93
PDB
D2 medium residues 94-151_275-399
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 33.0 3.80e-08 72.7% 20.6%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ihgA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 34.0 3.83e-01 76.5% 59.3%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 30.0 4.45e-01 90.7% 96.2%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 28.0 4.02e-01 87.4% 83.7%
8a0rA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.59 37.0 4.29e-01 93.4% 86.9%
2bduA02 1.10.150.340 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain 0.59 23.0 3.48e-01 91.8% 85.1%
2d4uB00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.59 38.0 4.18e-01 92.3% 77.4%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.58 39.0 4.60e-01 72.7% 96.9%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 45.0 4.18e-01 82.0% 90.1%
4neiA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.55 45.0 3.68e-01 97.3% 46.3%
3rvyA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.55 32.0 3.95e-01 90.2% 92.1%
8carA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.54 48.0 3.80e-01 95.6% 52.6%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 39.0 4.27e-01 92.9% 90.3%
2x1lA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 38.0 3.97e-01 86.3% 79.7%
2r17C00 1.25.40.660 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C 0.52 37.0 3.20e-01 100.0% 44.3%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.85 81.0 5.73e-01 100.0% 59.6%
3403421 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 42.0 4.70e-01 79.8% 81.1%
4019842 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 46.0 4.32e-01 91.3% 67.3%
3353637 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 34.0 3.57e-01 96.7% 61.3%
3176648 603.1.1.6 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.58 44.0 4.28e-01 77.6% 97.0%
3222674 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 33.0 3.38e-01 100.0% 55.1%
3795757 603.1.1.97 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.58 44.0 3.82e-01 78.1% 83.8%
3473984 603.1.1.97 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.57 48.0 4.23e-01 86.9% 83.5%
4013992 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.57 35.0 3.80e-01 89.6% 70.0%
4023121 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 46.0 4.11e-01 94.5% 61.6%
3471406 4266.3.1.1 ↗ alpha bundles › Hyaluronidase domain-like › FLJ32549 domain-like › FLJ32549 domain-like › C12orf66_like 0.57 38.0 4.07e-01 92.9% 76.9%
429313 109.4.1.288 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nro1_C 0.55 39.0 4.31e-01 96.7% 90.5%
3687571 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.54 36.0 4.03e-01 89.6% 85.7%
3442598 604.1.1.146 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4220 0.54 36.0 3.67e-01 78.1% 68.6%
3200100 109.4.1.356 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.54 46.0 4.25e-01 89.6% 80.0%
3246395 603.1.1.1 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.53 40.0 3.88e-01 77.6% 92.2%
3217606 192.29.1.172 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.53 33.0 3.41e-01 91.8% 63.9%
3503769 633.4.1.0 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.52 35.0 4.09e-01 70.5% 94.6%
3660528 109.4.1.1146 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_PUB 0.51 43.0 3.11e-01 96.2% 33.7%
3518225 109.4.1.292 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3a_PCI_TPR-like 0.50 41.0 3.08e-01 85.2% 57.0%
D3 medium residues 152-274
PDB
Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 31.9 8.10e-08 90.2% 18.2%
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.85 80.0 5.71e-01 100.0% 38.5%
1vyfA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.81 40.0 3.93e-01 79.7% 44.4%
1mdcA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.77 39.0 3.85e-01 80.5% 45.8%
1o8vA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.77 38.0 3.76e-01 80.5% 44.4%
4azpA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.75 38.0 3.69e-01 80.5% 44.0%
6fmeA03 2.20.220.10 Mainly Beta › Single Sheet › Glycosyl hydrolase fold › alpha-Amylases 0.75 38.0 5.40e-01 73.2% 100.0%
7wffb01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.65 49.0 3.70e-01 79.7% 100.0%
3actA01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.65 50.0 3.81e-01 81.3% 89.4%
6f91A01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.65 55.0 4.17e-01 90.2% 78.1%
2nvnA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.63 33.0 3.43e-01 78.0% 53.3%
2it9A00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.62 34.0 3.53e-01 79.7% 55.8%
3w7tA01 2.70.98.50 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › putative glycoside hydrolase family protein from bacillus halodurans 0.59 45.0 3.68e-01 80.5% 79.3%
1nkgA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.59 52.0 4.14e-01 96.7% 89.6%
6fopA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.58 47.0 3.90e-01 87.0% 78.3%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.58 47.0 4.06e-01 85.4% 96.8%
5gv0A00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.57 43.0 3.95e-01 78.9% 66.0%
3fyfA00 2.40.128.410 Mainly Beta › Beta Barrel › Lipocalin › 0.57 42.0 3.93e-01 76.4% 74.5%
2ffsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 43.0 4.11e-01 84.6% 67.6%
3ovcA01 3.30.200.150 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › 0.57 31.0 3.87e-01 93.5% 90.1%
1cgtA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.56 34.0 3.84e-01 95.1% 78.7%
2bujB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.56 33.0 3.67e-01 94.3% 74.5%
7szeB02 3.90.380.10 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 0.55 42.0 3.74e-01 100.0% 54.3%
4ggtB00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.55 40.0 4.34e-01 77.2% 88.7%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 41.0 4.00e-01 78.0% 71.1%
1wmiA00 3.30.2310.20 Alpha Beta › 2-Layer Sandwich › YaeB-like fold › RelE-like 0.55 30.0 3.45e-01 99.2% 72.7%
2d4rA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 42.0 4.00e-01 82.9% 71.2%
3jr1A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 33.0 3.63e-01 89.4% 75.8%
1pbyA02 2.40.128.120 Mainly Beta › Beta Barrel › Lipocalin › Quinohemoprotein amine dehydrogenase alpha subunit, domain 2 0.53 34.0 3.65e-01 76.4% 74.5%
3ijtB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 45.0 4.29e-01 91.9% 100.0%
3k0zA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 36.0 3.44e-01 70.7% 95.3%
2pcsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 39.0 3.62e-01 77.2% 69.7%
6xmtA02 3.40.1110.10 Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N 0.52 38.0 3.46e-01 76.4% 78.6%
6phxA03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 34.0 3.76e-01 82.1% 87.4%
3tfzB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 43.0 3.97e-01 92.7% 96.4%
4akmB00 2.40.160.110 Mainly Beta › Beta Barrel › Porin › 0.51 42.0 3.92e-01 87.8% 79.6%
1k8kF00 3.30.1460.20 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.51 37.0 3.34e-01 74.8% 64.7%
4e2oA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.51 32.0 3.59e-01 81.3% 86.4%
ECOD (28)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.85 79.0 5.02e-01 100.0% 23.9%
2095478 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.85 80.0 5.13e-01 100.0% 24.6%
2581425 12.1.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.82 37.0 5.54e-01 77.2% 98.2%
4046583 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.80 40.0 3.96e-01 79.7% 46.2%
4668044 9.1.1.1 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › Lipocalin 0.78 39.0 3.85e-01 79.7% 45.1%
3487462 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.77 39.0 3.87e-01 79.7% 46.2%
3962450 9.27.1.0 ↗ beta barrels › Lipocalins/Streptavidin › LpqH › LpqH 0.70 40.0 4.29e-01 77.2% 64.8%
5015778 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.68 53.0 4.11e-01 82.1% 84.5%
5025972 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.64 51.0 4.07e-01 84.6% 93.1%
3785596 216.1.1.2 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › Autophagy_act_C 0.62 45.0 4.04e-01 87.0% 55.8%
5791 295.1.1.6 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › DUF1818 0.62 34.0 3.54e-01 78.9% 57.1%
3519601 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.60 37.0 3.76e-01 76.4% 63.3%
3894207 3369.1.1.1 ↗ beta meanders › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › lysosome-associated membrane protein LAMP-3 › Lamp2-like_luminal 0.58 44.0 4.06e-01 78.9% 67.5%
5010009 12.3.1.40 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › TREH_N 0.56 45.0 4.04e-01 87.0% 100.0%
3282852 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.55 41.0 3.78e-01 75.6% 63.2%
3808409 331.3.1.43 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PDF2_C 0.55 39.0 3.13e-01 78.0% 36.7%
3593518 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.55 39.0 3.47e-01 73.2% 77.1%
4030275 267.1.1.0 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain 0.54 41.0 3.18e-01 79.7% 61.8%
3699264 883.1.1.9 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › SMP_LBD 0.54 41.0 3.54e-01 79.7% 92.1%
5009761 331.3.1.7 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › COXG 0.54 42.0 4.01e-01 82.9% 88.3%
3199320 4099.1.1.0 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.54 39.0 4.09e-01 82.1% 82.6%
3914464 11.1.1.562 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › BTBD16_C 0.53 37.0 3.62e-01 71.5% 82.9%
4964630 331.3.1.11 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Polyketide_cyc2 0.53 41.0 3.98e-01 82.9% 84.6%
3168452 331.10.2.3 ↗ a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase › Med1 0.53 34.0 3.70e-01 74.8% 76.2%
3286199 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.53 39.0 3.76e-01 82.9% 67.9%
4310253 9.1.1.14 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › CpeS 0.53 41.0 3.72e-01 82.1% 66.7%
4122018 4099.1.1.10 ↗ a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med1 0.52 34.0 3.70e-01 74.8% 79.0%
3989328 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.50 35.0 3.98e-01 95.9% 93.6%
D4 medium residues 483-506_526-554
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 21.5 1.20e-04 81.1% 4.0%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gxaE01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.56 39.0 3.64e-01 77.4% 89.0%
1vp7A00 1.10.287.1040 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit 0.52 37.0 3.46e-01 77.4% 75.0%
D5 medium residues 555-616
PDB
Domain cluster: rep: gH__YP_010087392__Vombatid_gammaherpesvirus_1__2052651__D555-613
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 40.9 2.30e-10 100.0% 40.4%
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3m1cA04 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.86 68.0 5.19e-01 91.9% 39.4%
2xqyA03 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.81 65.0 5.01e-01 98.4% 40.6%
7b7nH01 2.60.40.3190 Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain 0.80 67.0 5.19e-01 91.9% 44.1%
2e9wB05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.73 52.0 4.60e-01 75.8% 80.2%
6mv2A01 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.71 49.0 4.10e-01 72.6% 77.5%
1v4pC01 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.69 51.0 4.24e-01 79.0% 81.5%
5k3xA02 2.60.40.650 Mainly Beta › Sandwich › Immunoglobulin-like › 0.68 48.0 3.98e-01 75.8% 60.2%
5ds1A00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.67 46.0 3.98e-01 71.0% 100.0%
4i0kA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.67 49.0 4.28e-01 79.0% 73.7%
4eaeA00 2.60.40.4170 Mainly Beta › Sandwich › Immunoglobulin-like › 0.66 51.0 3.62e-01 82.3% 69.0%
1lomA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.66 40.0 3.45e-01 82.3% 36.6%
7k0xA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 46.0 4.32e-01 74.2% 80.8%
2zzeA04 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.66 50.0 4.37e-01 82.3% 80.0%
2y7bA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.66 50.0 3.83e-01 80.6% 64.2%
2xcmC00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.66 47.0 4.11e-01 75.8% 88.0%
4g6iB01 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.65 54.0 4.75e-01 90.3% 88.8%
4feiA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.64 45.0 3.81e-01 74.2% 87.3%
1i8dA01 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.63 53.0 4.71e-01 91.9% 88.8%
5e9aB03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.63 45.0 4.60e-01 75.8% 100.0%
3kewB02 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.63 49.0 3.74e-01 83.9% 85.4%
1shsA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.63 46.0 3.80e-01 79.0% 92.2%
1kzlA02 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.63 52.0 4.39e-01 90.3% 78.2%
4ktpA01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.63 47.0 3.17e-01 82.3% 76.0%
1xxaC00 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.62 47.0 4.49e-01 82.3% 93.2%
3bpnC03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 46.0 3.88e-01 79.0% 70.3%
6wy9B02 2.40.110.10 Mainly Beta › Beta Barrel › Butyryl-CoA Dehydrogenase, subunit A; domain 2 › Butyryl-CoA Dehydrogenase, subunit A, domain 2 0.61 44.0 3.88e-01 77.4% 92.6%
2je8B05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 44.0 3.89e-01 75.8% 66.3%
1azpA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.61 45.0 4.47e-01 83.9% 74.2%
2yn5A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 45.0 4.22e-01 82.3% 73.4%
7pjjA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 44.0 3.50e-01 80.6% 75.4%
4hikA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.59 53.0 4.06e-01 100.0% 60.9%
1nvpD02 2.30.18.10 Mainly Beta › Roll › TATA box binding Protein, subunit D; domain 2 › Transcription factor IIA (TFIIA), beta-barrel domain 0.58 38.0 4.35e-01 77.4% 91.3%
2e8yA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.58 41.0 3.68e-01 74.2% 87.8%
1nh2D02 2.30.18.10 Mainly Beta › Roll › TATA box binding Protein, subunit D; domain 2 › Transcription factor IIA (TFIIA), beta-barrel domain 0.57 39.0 4.29e-01 79.0% 91.7%
1h54B01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.56 41.0 2.73e-01 79.0% 63.9%
1pbyA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 41.0 3.87e-01 79.0% 75.0%
4j3vA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 39.0 3.35e-01 74.2% 57.1%
2f8lA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.56 47.0 3.29e-01 100.0% 39.4%
5eiqA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 39.0 3.51e-01 79.0% 68.1%
3jamD02 3.30.1140.32 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Ribosomal protein S3, C-terminal domain 0.54 39.0 3.12e-01 77.4% 66.2%
2wanA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 36.0 3.20e-01 74.2% 59.8%
5gtqA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.53 40.0 2.57e-01 82.3% 90.2%
2ns9A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 46.0 3.54e-01 100.0% 57.4%
3fcxB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 44.0 2.92e-01 95.2% 52.7%
3vskA01 3.90.1310.10 Alpha Beta › Alpha-Beta Complex › Penicillin-binding protein 2a (Domain 2) › Penicillin-binding protein 2a (Domain 2) 0.52 45.0 3.47e-01 93.5% 90.2%
2covG00 2.60.40.2450 Mainly Beta › Sandwich › Immunoglobulin-like › Beta-1,3-xylanase, CBM31 domain 0.52 37.0 3.41e-01 79.0% 67.0%
2q7nA05 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 42.0 3.64e-01 91.9% 80.6%
7mjrA04 2.60.40.1790 Mainly Beta › Sandwich › Immunoglobulin-like › Fungal immunomodulatory protein Fve 0.51 39.0 3.53e-01 88.7% 82.6%
3lidA03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.50 35.0 3.11e-01 75.8% 77.1%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
119479 3145.1.1.1 ↗ beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.87 72.0 5.30e-01 100.0% 37.4%
1309233 3145.1.1.1 ↗ beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.81 65.0 4.87e-01 98.4% 36.5%
2095502 3145.1.1.1 ↗ beta sandwiches › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › C-terminal domain of envelope glycoprotein H › Herpes_glycoH_C 0.76 68.0 5.13e-01 100.0% 42.1%
3847907 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.72 52.0 4.44e-01 75.8% 84.2%
3907054 319.1.1.3 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.71 49.0 4.14e-01 72.6% 80.0%
3881301 11.1.1.363 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C2-set_3 0.68 49.0 4.32e-01 75.8% 75.6%
3686135 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.68 53.0 4.28e-01 85.5% 74.2%
4523743 309.1.2.1 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › tRNA_SAD 0.67 50.0 3.58e-01 79.0% 74.9%
4678749 306.1.1.0 ↗ a+b two layers › Glucose permease domain IIB-like › Glucose permease domain IIB › Glucose permease domain IIB 0.67 50.0 4.99e-01 80.6% 81.5%
4289387 309.1.2.1 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › tRNA_SAD 0.66 50.0 3.61e-01 82.3% 76.0%
4964479 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.66 48.0 3.87e-01 77.4% 86.1%
5014095 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 48.0 4.94e-01 79.0% 83.3%
3897566 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 48.0 4.35e-01 80.6% 74.1%
3923465 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.64 45.0 3.81e-01 75.8% 86.7%
5052471 212.1.1.3 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N 0.62 45.0 3.06e-01 77.4% 53.6%
5054813 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.62 48.0 3.38e-01 85.5% 88.6%
3337623 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.62 46.0 3.86e-01 79.0% 94.3%
4602902 319.1.1.1 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.62 43.0 3.40e-01 74.2% 72.3%
3415261 220.1.1.5 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PID 0.60 46.0 3.36e-01 80.6% 42.6%
3208784 220.1.1.13 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › DCP1 0.60 45.0 3.35e-01 80.6% 46.3%
3692875 109.21.1.2 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nup96 0.60 43.0 2.44e-01 75.8% 50.8%
4145032 12.3.1.69 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › DUF4861 0.60 44.0 2.87e-01 79.0% 54.4%
4015971 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.59 52.0 4.65e-01 96.8% 100.0%
3259285 12.3.1.19 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › Gal_mutarotas_2 0.58 44.0 2.90e-01 85.5% 72.9%
3395612 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 43.0 3.62e-01 79.0% 59.0%
3797646 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 43.0 3.57e-01 79.0% 55.5%
3291389 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.57 42.0 3.22e-01 80.6% 85.8%
3416552 11.1.1.673 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CUT_N 0.57 42.0 3.56e-01 79.0% 56.2%
3623374 11.1.1.673 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CUT_N 0.57 41.0 3.46e-01 80.6% 65.2%
3288281 881.1.1.15 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like › DUF3558 0.56 48.0 3.73e-01 96.8% 70.4%
4464583 241.1.1.2 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Autophagy_act_C 0.56 48.0 3.37e-01 93.5% 85.3%
5003221 241.15.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.55 47.0 3.90e-01 96.8% 84.3%
4545116 12.3.1.24 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich › YidC_periplas 0.55 41.0 2.79e-01 85.5% 80.0%
3392553 11.1.1.673 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CUT_N 0.54 42.0 3.50e-01 82.3% 68.2%
4160946 212.1.1.9 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › DNA_mis_repair 0.54 45.0 3.89e-01 100.0% 90.0%
4990958 212.1.1.60 ↗ a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Nre_N 0.54 39.0 2.87e-01 77.4% 66.3%
3396112 10.32.1.235 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › MBF2 0.54 41.0 3.54e-01 83.9% 74.0%
3163889 2.1.1.139 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Slp 0.53 48.0 3.73e-01 98.4% 52.8%
5030173 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 38.0 3.49e-01 77.4% 72.5%
3438388 331.4.1.2 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › NAF 0.52 39.0 3.15e-01 83.9% 71.9%
3401203 59.1.3.0 ↗ beta complex topology › triple barrel › triple barrel › RNA polymerase I subunits A49/A34.5 dimerization domains 0.51 36.0 3.22e-01 72.6% 61.2%
3869235 2007.5.1.21 ↗ a/b three-layered sandwiches › Flavodoxin-like › SGNH hydrolase › SGNH hydrolase › NXPE4_C 0.51 39.0 2.58e-01 98.4% 16.9%
3582408 11.1.1.673 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › CUT_N 0.51 37.0 3.08e-01 79.0% 82.6%
3800952 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.50 42.0 2.94e-01 95.2% 95.0%