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glycoprotein_H

Euk-Vir

Rhinolophus_gammaherpesvirus_1

glycoprotein_H__YP_009551832__Rhinolophus_gammaherpesvirus_1__2054179

Identity

Accession:
YP_009551832 ↗
Protein ID:
glycoprotein_H
Kingdom:
euk

Quality

79.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Percavirus› Rhinolophus_gammaherpesvirus_1

TaxID: 2054179

Cluster

View cluster (43 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 160-201_313-412
PDB
Domain cluster: rep: Glycoprotein_H__YP_009552485__Eptesicus_fuscus_gammaherpesvirus__2035399__D124-144_159-177_315-399
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 67.1 1.70e-18 75.3% 20.8%
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.90 86.0 6.35e-01 100.0% 77.8%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.75 41.0 5.43e-01 95.1% 97.5%
2d2sA01 1.20.58.1210 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain 0.71 42.0 4.66e-01 70.4% 72.4%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 45.0 5.40e-01 95.1% 95.9%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 46.0 5.36e-01 93.7% 97.1%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.66 38.0 4.03e-01 93.7% 63.5%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.65 37.0 4.49e-01 95.8% 89.4%
5nl6B01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 46.0 4.99e-01 95.1% 84.3%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.65 41.0 4.93e-01 80.3% 97.8%
3eabE00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 39.0 4.85e-01 96.5% 98.8%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.65 42.0 4.92e-01 95.8% 93.9%
6t0bc01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 33.0 4.36e-01 73.9% 89.7%
3ay5A01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.63 44.0 4.54e-01 72.5% 75.9%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 42.0 4.83e-01 93.0% 91.5%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 43.0 4.94e-01 95.1% 97.1%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 43.0 4.91e-01 92.3% 95.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 42.0 4.75e-01 93.0% 92.5%
7oq4Z01 1.20.120.950 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 0.61 28.0 3.32e-01 96.5% 61.2%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.60 35.0 4.32e-01 94.4% 95.2%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.59 43.0 4.73e-01 81.0% 92.4%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.57 29.0 3.92e-01 78.9% 95.8%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.56 32.0 3.69e-01 76.1% 76.5%
3dyjA01 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.56 40.0 3.83e-01 74.6% 62.7%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 38.0 4.13e-01 97.9% 87.1%
7miqA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 37.0 4.09e-01 98.6% 88.2%
1blwC00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.52 40.0 4.07e-01 80.3% 81.6%
1wjoA01 1.10.418.10 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain 0.52 30.0 3.56e-01 70.4% 79.8%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.51 41.0 3.91e-01 95.8% 72.8%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4974685 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 44.0 5.70e-01 95.1% 98.8%
3724003 622.1.1.0 ↗ alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.70 46.0 5.40e-01 97.2% 94.0%
3479092 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 43.0 5.04e-01 95.1% 91.0%
3577937 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 45.0 4.98e-01 95.1% 84.3%
3626530 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.67 42.0 4.93e-01 95.1% 92.6%
4331100 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 40.0 4.73e-01 95.8% 91.6%
4056158 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.64 40.0 4.44e-01 96.5% 80.0%
3341060 6155.1.1.6 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › DUF2921 0.63 38.0 4.66e-01 95.1% 97.6%
3619724 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.61 39.0 4.45e-01 96.5% 89.0%
3941457 1203.1.2.3 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › YiaAB 0.60 39.0 4.25e-01 92.3% 78.3%
3218641 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.59 42.0 4.51e-01 95.8% 85.0%
3940580 604.6.1.14 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › RasGAP_C 0.58 40.0 4.37e-01 94.4% 86.1%
3733339 3324.1.1.0 ↗ extended segments › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases › Helical arch in Ski2-like helicases 0.56 32.0 3.47e-01 81.7% 63.2%
3268032 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.56 36.0 3.87e-01 87.3% 75.0%
3544470 633.23.1.1 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin 0.56 45.0 4.32e-01 95.8% 73.3%
3831865 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.56 40.0 4.17e-01 95.8% 80.8%
4971759 5059.1.1.1 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.55 33.0 3.38e-01 75.4% 58.6%
5056276 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.53 37.0 3.56e-01 70.4% 89.4%
3461715 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.53 35.0 4.17e-01 75.4% 96.0%
3584512 632.19.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A 0.52 32.0 3.90e-01 85.9% 100.0%
3419489 632.7.1.27 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › Rx_N 0.51 37.0 3.82e-01 86.6% 78.5%
3614423 109.4.1.210 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.51 45.0 2.88e-01 93.0% 34.9%
D2 medium residues 202-312
PDB
Domain cluster: rep: orf22__YP_009044405__Alcelaphine_gammaherpesvirus_2__138184__D149-254
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 92.7 3.10e-26 100.0% 21.0%
D3 medium residues 413-612
PDB
Domain cluster: rep: BXLF2__YP_001129496__Human_herpesvirus_4_type_2__12509__D346-529
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02489.22 best Herpes_glycop_H 176.5 1.20e-51 91.5% 36.3%
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ro3A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 42.0 4.69e-01 100.0% 81.8%
4yvoA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 38.0 4.71e-01 92.0% 99.2%
2vq2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 36.0 3.56e-01 100.0% 51.4%
5bz1A00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.60 53.0 4.31e-01 98.0% 50.7%
4gpkF02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 37.0 3.53e-01 93.0% 50.0%
3ceqA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 45.0 4.21e-01 100.0% 62.0%
4abnA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.60 37.0 3.33e-01 92.5% 43.4%
2qk2A01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.59 49.0 4.66e-01 100.0% 75.2%
1hzfA00 1.50.10.20 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.58 49.0 4.29e-01 90.0% 76.5%
4c9bB00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.58 51.0 4.54e-01 94.5% 70.0%
3urzA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.56 36.0 3.67e-01 84.5% 62.9%
7cc7A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.55 43.0 4.15e-01 97.0% 72.4%
2wpvE00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 44.0 3.97e-01 98.5% 61.8%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.54 29.0 3.81e-01 73.0% 95.3%
2qr4A01 1.20.140.70 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain 0.53 38.0 4.27e-01 77.5% 93.6%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 43.0 4.47e-01 99.5% 95.7%
3d3mA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 39.0 4.31e-01 94.0% 98.8%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.51 43.0 4.15e-01 91.5% 78.2%
1ug3A01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 41.0 4.20e-01 87.5% 86.7%
3qkyA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 43.0 3.97e-01 95.5% 70.5%
1h2tC03 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.51 43.0 4.05e-01 99.5% 75.2%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.50 27.0 3.47e-01 71.5% 88.6%
3gw4A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 37.0 3.85e-01 98.0% 80.2%
2xpiD00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.50 46.0 3.41e-01 99.5% 63.3%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2701125 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.90 77.0 5.54e-01 94.0% 35.6%
2095478 3146.1.1.1 ↗ a+b complex topology › gH main domain › gH main domain › gH main domain › Herpes_glycop_H 0.88 79.0 5.66e-01 94.0% 36.3%
3199705 109.4.1.1348 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_7, TPR_10, TPR_12 0.63 42.0 3.96e-01 100.0% 54.3%
2765423 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 41.0 4.52e-01 97.0% 81.4%
4825023 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.62 58.0 5.82e-01 100.0% 100.0%
3919495 109.4.1.20 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RYDR_ITPR 0.61 56.0 3.43e-01 100.0% 19.9%
4027684 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 53.0 5.00e-01 94.5% 100.0%
4516223 109.4.1.198 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.60 40.0 4.40e-01 95.5% 81.2%
3506230 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 45.0 4.44e-01 100.0% 73.8%
3405087 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 47.0 4.94e-01 93.0% 92.4%
3535079 109.4.1.88 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MUN 0.58 47.0 3.94e-01 87.5% 80.0%
3209733 109.4.1.777 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 45.0 3.57e-01 81.0% 94.6%
4029990 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 52.0 3.67e-01 100.0% 33.3%
3331011 109.4.1.194 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 0.56 47.0 4.21e-01 100.0% 62.9%
1181564 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 40.0 4.43e-01 100.0% 90.2%
3738327 109.4.1.536 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Mei4 0.56 46.0 4.36e-01 88.0% 82.9%
3412498 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.56 46.0 4.28e-01 89.0% 75.8%
3927844 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 49.0 4.61e-01 98.0% 95.1%
3865100 109.4.1.368 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR 0.53 45.0 3.97e-01 96.5% 61.4%
3289148 109.4.1.194 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_10 0.53 46.0 4.50e-01 100.0% 83.6%
3400447 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 47.0 4.53e-01 100.0% 85.7%
3496403 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 48.0 4.11e-01 98.5% 62.9%
3575436 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.53 46.0 4.05e-01 96.5% 64.5%
4945269 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 37.0 3.77e-01 86.0% 72.0%
4949689 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 39.0 4.17e-01 95.0% 90.3%
3605579 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 45.0 4.04e-01 98.0% 67.6%
3622264 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 44.0 4.19e-01 98.5% 80.0%
3689557 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 39.0 4.18e-01 91.5% 93.5%
4328726 109.4.1.1139 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HIR3_TPR_N 0.50 44.0 4.06e-01 95.5% 82.7%
D4 medium residues 613-747
PDB
Domain cluster: rep: UL22__YP_003084400__Anatid_alphaherpesvirus_1__104388__D647-783
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF17488.8 best Herpes_glycoH_C 162.8 5.70e-48 100.0% 91.5%