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gwf1_scaffold_41_prodigal-single.1__X__X__00336
Bact-Virgwf1_scaffold_41_prodigal-single.1__X__X__00336
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-35_99-223
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ip8A00 | 1.10.132.110 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein | 0.59 | 33.0 | 4.02e-01 | 90.6% | 82.9% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.58 | 28.0 | 3.41e-01 | 98.1% | 70.6% |
| 1cg5B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 34.0 | 3.61e-01 | 76.9% | 64.5% |
| 1wolA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 28.0 | 3.22e-01 | 96.2% | 60.7% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 33.0 | 3.49e-01 | 76.9% | 63.0% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 25.0 | 3.26e-01 | 98.1% | 77.0% |
| 4eadA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.53 | 30.0 | 3.55e-01 | 92.5% | 80.4% |
| 3b81A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 31.0 | 2.96e-01 | 77.5% | 49.2% |
| 6umqA01 | 1.20.930.60 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.52 | 34.0 | 3.89e-01 | 98.8% | 90.4% |
| 2i9cA01 | 1.25.40.70 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) | 0.52 | 27.0 | 3.16e-01 | 89.4% | 69.4% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.51 | 35.0 | 3.71e-01 | 75.0% | 79.1% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 31.0 | 3.15e-01 | 75.6% | 61.4% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5054557 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.73 | 41.0 | 5.32e-01 | 71.9% | 96.7% |
| 3236222 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.66 | 29.0 | 2.88e-01 | 98.8% | 39.4% |
| 3598051 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 33.0 | 3.71e-01 | 96.9% | 68.8% |
| 3703129 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 32.0 | 3.01e-01 | 99.4% | 45.0% |
| 5028018 | 5045.1.1.0 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A | 0.50 | 42.0 | 3.46e-01 | 90.6% | 63.3% |
| 4025485 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.50 | 31.0 | 3.12e-01 | 96.9% | 56.5% |
D2
medium
residues 36-98
Domain cluster:
representative
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ebjA01 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.69 | 58.0 | 4.56e-01 | 98.4% | 45.3% |
| 2bmjA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 49.0 | 3.56e-01 | 76.2% | 36.2% |
| 1yu9A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 45.0 | 3.36e-01 | 71.4% | 40.7% |
| 2x5rA01 | 3.30.470.40 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › | 0.65 | 52.0 | 4.29e-01 | 88.9% | 79.1% |
| 2v5nA02 | 2.70.130.10 | Mainly Beta › Distorted Sandwich › Cation-dependent Mannose-6-phosphate Receptor; Chain A › Mannose-6-phosphate receptor binding domain | 0.63 | 53.0 | 4.24e-01 | 98.4% | 96.3% |
| 3wp4A00 | 2.60.120.180 | Mainly Beta › Sandwich › Jelly Rolls › Glycoside hydrolase family 11/12, catalytic domain | 0.63 | 55.0 | 3.70e-01 | 96.8% | 39.0% |
| 1qs1A02 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.62 | 53.0 | 3.74e-01 | 96.8% | 61.4% |
| 4xsgB00 | 3.90.176.10 | Alpha Beta › Alpha-Beta Complex › Toxin ADP-ribosyltransferase; Chain A, domain 1 › Toxin ADP-ribosyltransferase; Chain A, domain 1 | 0.61 | 52.0 | 3.64e-01 | 95.2% | 64.4% |
| 2x8xX03 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.61 | 42.0 | 3.83e-01 | 71.4% | 98.8% |
| 6he0A01 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.60 | 48.0 | 4.11e-01 | 90.5% | 57.0% |
| 4dg8A02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.60 | 43.0 | 3.86e-01 | 88.9% | 53.3% |
| 4k3cA01 | 3.10.20.310 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › membrane protein fhac | 0.59 | 41.0 | 3.79e-01 | 73.0% | 98.8% |
| 1h6uA03 | 2.60.40.1220 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.59 | 46.0 | 3.97e-01 | 87.3% | 100.0% |
| 2y27A02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.58 | 46.0 | 4.05e-01 | 92.1% | 59.2% |
| 7r7eA01 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.57 | 46.0 | 3.89e-01 | 93.7% | 52.1% |
| 1ib8A01 | 3.30.300.70 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › RimP-like superfamily, N-terminal | 0.57 | 47.0 | 4.30e-01 | 90.5% | 73.5% |
| 2rl8A00 | 2.70.130.10 | Mainly Beta › Distorted Sandwich › Cation-dependent Mannose-6-phosphate Receptor; Chain A › Mannose-6-phosphate receptor binding domain | 0.57 | 47.0 | 3.74e-01 | 98.4% | 43.9% |
| 4mh4A02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.57 | 48.0 | 4.22e-01 | 93.7% | 68.1% |
| 3gwyB00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.57 | 41.0 | 3.30e-01 | 79.4% | 69.2% |
| 8c5yA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.56 | 46.0 | 3.39e-01 | 90.5% | 70.6% |
| 4dywA00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.56 | 39.0 | 3.15e-01 | 73.0% | 69.8% |
| 4r0mA02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.56 | 47.0 | 4.03e-01 | 96.8% | 56.5% |
| 3bypA00 | 3.30.70.1350 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain | 0.55 | 45.0 | 4.20e-01 | 95.2% | 73.2% |
| 2kdnA00 | 3.30.300.90 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › BolA-like | 0.55 | 46.0 | 3.95e-01 | 98.4% | 80.6% |
| 3wgtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.54 | 45.0 | 3.21e-01 | 93.7% | 84.8% |
| 3kxwA02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.54 | 45.0 | 3.66e-01 | 93.7% | 51.6% |
| 6o6eB02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.54 | 41.0 | 3.51e-01 | 88.9% | 49.5% |
| 4i1sB00 | 4.10.80.340 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › | 0.54 | 34.0 | 3.71e-01 | 96.8% | 78.8% |
| 2ql8A00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.54 | 46.0 | 3.57e-01 | 96.8% | 46.4% |
| 5b55A01 | 3.40.50.1100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.54 | 45.0 | 3.36e-01 | 100.0% | 90.0% |
| 3tghA00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.53 | 48.0 | 3.03e-01 | 100.0% | 37.5% |
| 4ys4A02 | 2.60.40.2860 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 44.0 | 3.62e-01 | 98.4% | 97.7% |
| 1khbA01 | 3.40.449.10 | Alpha Beta › 3-Layer(aba) Sandwich › Phosphoenolpyruvate Carboxykinase; domain 1 › Phosphoenolpyruvate Carboxykinase, domain 1 | 0.53 | 41.0 | 3.01e-01 | 93.7% | 75.3% |
| 3bamA00 | 3.40.91.20 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › | 0.53 | 46.0 | 3.28e-01 | 100.0% | 60.2% |
| 6vhvA01 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.52 | 38.0 | 3.43e-01 | 93.7% | 53.8% |
| 3w5xA00 | 3.30.70.1350 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cation efflux protein, cytoplasmic domain | 0.52 | 40.0 | 3.88e-01 | 93.7% | 75.0% |
| 2ookA00 | 3.40.50.10600 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SpoIIaa-like domains | 0.52 | 42.0 | 3.33e-01 | 87.3% | 46.4% |
| 3n7zA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 42.0 | 3.40e-01 | 95.2% | 78.0% |
| 1ym5A01 | 3.10.310.10 | Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 | 0.50 | 42.0 | 3.33e-01 | 96.8% | 44.1% |
ECOD (47)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4027367 | 2004.1.1.571 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras, MMR_HSR1 | 0.72 | 49.0 | 3.40e-01 | 71.4% | 30.0% |
| 5034595 | 4272.1.1.1 ↗ | a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa | 0.70 | 61.0 | 4.42e-01 | 96.8% | 50.0% |
| 4930534 | 4272.1.1.1 ↗ | a+b two layers › Nqo5-like › Nqo5-like › Nqo5-like › Complex1_30kDa | 0.64 | 56.0 | 4.16e-01 | 100.0% | 49.7% |
| 3599576 | 63.1.1.0 ↗ | beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain | 0.64 | 54.0 | 3.97e-01 | 96.8% | 87.2% |
| 5021698 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.63 | 52.0 | 3.58e-01 | 100.0% | 32.8% |
| 4944491 | 221.4.1.0 ↗ | a+b two layers › beta-Grasp › Nudix › Nudix | 0.63 | 44.0 | 3.40e-01 | 73.0% | 67.9% |
| 3945514 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 53.0 | 3.53e-01 | 96.8% | 93.0% |
| 3301236 | 63.1.1.0 ↗ | beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain | 0.61 | 51.0 | 3.84e-01 | 96.8% | 88.2% |
| 3503356 | 224.1.1.0 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like | 0.61 | 45.0 | 3.88e-01 | 93.7% | 51.6% |
| 3700562 | 63.1.1.0 ↗ | beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain | 0.60 | 52.0 | 4.09e-01 | 98.4% | 91.9% |
| 3488689 | 508.1.1.0 ↗ | a+b three layers › Protein interacting with HSP90 1 (Pih1) N-terminal domain › Protein interacting with HSP90 1 (Pih1) N-terminal domain › Protein interacting with HSP90 1 (Pih1) N-terminal domain | 0.60 | 48.0 | 3.98e-01 | 95.2% | 50.0% |
| 3735941 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.60 | 50.0 | 4.57e-01 | 95.2% | 70.6% |
| 4978996 | 2004.11.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › PEP carboxykinase N-terminal domain › PEP carboxykinase N-terminal domain | 0.59 | 50.0 | 3.52e-01 | 96.8% | 83.3% |
| 3997846 | 207.1.1.142 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_4, LRR_6, LRR_8 | 0.59 | 48.0 | 2.83e-01 | 93.7% | 11.9% |
| 3743726 | 327.5.1.7 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › Mug62 | 0.59 | 48.0 | 3.73e-01 | 92.1% | 51.0% |
| 4943019 | 327.11.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II) | 0.58 | 46.0 | 4.51e-01 | 87.3% | 84.3% |
| 4958712 | 327.5.1.3 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C_2 | 0.58 | 48.0 | 4.16e-01 | 92.1% | 61.0% |
| 4021181 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.58 | 46.0 | 3.65e-01 | 88.9% | 50.0% |
| 3966350 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.58 | 43.0 | 3.65e-01 | 90.5% | 47.6% |
| 4146797 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.57 | 45.0 | 3.68e-01 | 88.9% | 56.2% |
| 3277889 | 327.5.1.6 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-dom_DIP2-like | 0.57 | 47.0 | 3.95e-01 | 93.7% | 53.9% |
| 3436847 | 2.2.1.12 ↗ | beta barrels › OB-fold › Bacterial enterotoxins › Bacterial enterotoxins › DUF7851 | 0.57 | 48.0 | 3.80e-01 | 90.5% | 60.5% |
| 4622549 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.57 | 46.0 | 3.70e-01 | 88.9% | 57.6% |
| 3545493 | 224.1.1.2 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin | 0.57 | 50.0 | 3.74e-01 | 98.4% | 51.0% |
| 4478632 | 224.1.1.2 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Gelsolin | 0.57 | 51.0 | 3.11e-01 | 100.0% | 32.7% |
| 3710133 | 327.7.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like | 0.57 | 45.0 | 3.59e-01 | 95.2% | 41.4% |
| 4985935 | 7512.1.1.18 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycogen_syn | 0.56 | 44.0 | 2.88e-01 | 85.7% | 38.2% |
| 4125352 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.56 | 45.0 | 3.60e-01 | 88.9% | 58.5% |
| 3968847 | 2486.1.1.8 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › Peptidase_S41,DUF3340 | 0.56 | 51.0 | 3.13e-01 | 100.0% | 36.2% |
| 3604419 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.56 | 44.0 | 3.60e-01 | 92.1% | 52.6% |
| 4985883 | 266.1.1.1 ↗ | a+b two layers › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylate synthase/dCMP hydroxymethylase › Thymidylat_synt | 0.55 | 47.0 | 3.36e-01 | 100.0% | 37.1% |
| 3947813 | 316.1.1.46 ↗ | a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › SseB_C | 0.55 | 45.0 | 3.92e-01 | 92.1% | 59.0% |
| 3938551 | 5.1.12.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › PERK and Ire1 luminal domains | 0.55 | 42.0 | 2.77e-01 | 82.5% | 46.3% |
| 5081027 | 327.7.1.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › ZT_dimer | 0.54 | 43.0 | 4.06e-01 | 95.2% | 72.5% |
| 3357867 | 7579.1.1.14 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Lipase_3 | 0.54 | 50.0 | 3.32e-01 | 100.0% | 91.7% |
| 3577103 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.54 | 47.0 | 3.88e-01 | 100.0% | 77.5% |
| 3938771 | 10.10.1.0 ↗ | beta sandwiches › jelly-roll › Lipase/lipooxygenase domain (PLAT/LH2 domain) › Lipase/lipooxygenase domain (PLAT/LH2 domain) | 0.53 | 43.0 | 3.75e-01 | 90.5% | 59.2% |
| 4413560 | 3121.1.1.5 ↗ | a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA_3 | 0.53 | 38.0 | 3.59e-01 | 74.6% | 98.7% |
| 4228205 | 324.1.1.1 ↗ | a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC | 0.53 | 45.0 | 3.55e-01 | 98.4% | 47.1% |
| 3705026 | 224.1.1.1 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like › Cofilin_ADF | 0.53 | 44.0 | 3.44e-01 | 93.7% | 45.7% |
| 4127161 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.52 | 44.0 | 3.83e-01 | 96.8% | 76.0% |
| 118104 | 2496.1.1.4 ↗ | a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › SpoIIAA-like | 0.51 | 42.0 | 3.41e-01 | 93.7% | 47.5% |
| 3329729 | 5104.1.1.3 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA2 | 0.51 | 42.0 | 3.30e-01 | 95.2% | 46.9% |
| 3959726 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.51 | 42.0 | 2.86e-01 | 96.8% | 32.5% |
| 3401220 | 2496.1.1.0 ↗ | a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like | 0.51 | 43.0 | 3.45e-01 | 95.2% | 50.4% |
| 5037577 | 4961.1.1.1 ↗ | a+b complex topology › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › inserted a+b domain in yeast RNA polymerase beta subunit › RNA_pol_Rpb2_4 | 0.50 | 42.0 | 3.68e-01 | 92.1% | 92.6% |
| 3924166 | 7579.1.1.1 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › COesterase | 0.50 | 44.0 | 2.55e-01 | 98.4% | 14.1% |