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gwf2_scaffold_96_prodigal-single.1__X__X__00032
Bact-Virgwf2_scaffold_96_prodigal-single.1__X__X__00032
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 19-157
Domain cluster:
representative
D2
high
residues 165-262_319-342
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09709.16 best | Cas_Csd1 | 49.5 | 4.00e-13 | 80.3% | 12.3% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1krlA00 | 6.20.50.130 | Special › Other non-globular › N-terminal domain of TfIIb › | 0.69 | 23.0 | 3.84e-01 | 80.3% | 84.1% |
| 3d2fA03 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.67 | 26.0 | 3.05e-01 | 84.4% | 48.4% |
| 4h5iB00 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.62 | 37.0 | 2.64e-01 | 86.9% | 20.6% |
| 4r80A00 | 3.10.450.630 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.58 | 33.0 | 4.17e-01 | 84.4% | 92.1% |
| 1fwxA01 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.53 | 37.0 | 2.57e-01 | 72.1% | 78.2% |
| 2d9qB01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 28.0 | 3.09e-01 | 82.0% | 66.0% |
| 6u5uG07 | 3.30.1120.100 | Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › | 0.51 | 38.0 | 3.74e-01 | 86.1% | 72.7% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3579989 | 5.1.4.116 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › IKI3 | 0.63 | 37.0 | 2.66e-01 | 87.7% | 20.0% |
| 4220637 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.62 | 37.0 | 2.62e-01 | 86.1% | 20.0% |
| 5062732 | 4312.1.1.0 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like | 0.61 | 39.0 | 4.61e-01 | 86.1% | 91.8% |
| 5026576 | 331.1.1.0 ↗ | a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like | 0.61 | 30.0 | 3.57e-01 | 87.7% | 67.1% |
| 4988629 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.60 | 36.0 | 2.74e-01 | 83.6% | 26.0% |
| 3625916 | 5.1.3.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed | 0.57 | 39.0 | 2.76e-01 | 97.5% | 22.6% |
| 4926940 | 4312.1.1.0 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like | 0.57 | 35.0 | 3.13e-01 | 74.6% | 43.4% |
| 3607354 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.57 | 35.0 | 3.35e-01 | 83.6% | 53.6% |
| 4939212 | 244.4.1.1 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › Complex1_49kDa | 0.55 | 26.0 | 2.88e-01 | 92.6% | 52.6% |
| 3589620 | 4312.1.1.11 ↗ | a+b two layers › RelE-like › RelE-like › RelE-like › ParE-like_toxin | 0.54 | 36.0 | 4.16e-01 | 77.0% | 93.3% |
| 3245973 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.52 | 37.0 | 2.51e-01 | 84.4% | 20.0% |
| 4932759 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 25.0 | 3.08e-01 | 81.1% | 72.0% |
| 3643787 | 5.1.3.142 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_AT5G49610-like | 0.51 | 35.0 | 2.51e-01 | 86.1% | 23.7% |
| 3640668 | 719.1.1.2 ↗ | beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › XLF | 0.51 | 38.0 | 3.81e-01 | 78.7% | 77.6% |
| 3407108 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.50 | 36.0 | 2.69e-01 | 76.2% | 97.0% |
D3
medium
residues 343-470
Domain cluster:
representative
CATH (35)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.62 | 45.0 | 3.86e-01 | 75.8% | 78.6% |
| 7zh0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.60 | 55.0 | 3.84e-01 | 99.2% | 87.5% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 42.0 | 4.57e-01 | 93.0% | 90.1% |
| 2x1lA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.60 | 49.0 | 4.46e-01 | 87.5% | 83.7% |
| 2q9rA01 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.58 | 44.0 | 3.85e-01 | 93.0% | 51.8% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.58 | 43.0 | 4.77e-01 | 78.1% | 100.0% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.57 | 38.0 | 4.45e-01 | 82.0% | 100.0% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.57 | 38.0 | 4.37e-01 | 82.0% | 94.6% |
| 1ihgA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 40.0 | 3.89e-01 | 73.4% | 70.3% |
| 5gl7A01 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.56 | 48.0 | 4.45e-01 | 93.0% | 81.3% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.56 | 46.0 | 4.06e-01 | 87.5% | 70.1% |
| 1sr2A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.56 | 33.0 | 3.52e-01 | 71.9% | 65.5% |
| 1s0pA01 | 1.25.40.330 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain | 0.55 | 44.0 | 4.02e-01 | 85.2% | 94.7% |
| 3craA02 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.55 | 39.0 | 4.00e-01 | 100.0% | 73.4% |
| 4lixA03 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.55 | 48.0 | 3.98e-01 | 96.9% | 89.4% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.55 | 43.0 | 4.07e-01 | 82.0% | 100.0% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.54 | 43.0 | 3.34e-01 | 84.4% | 71.8% |
| 4e6hA00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 48.0 | 3.23e-01 | 100.0% | 64.6% |
| 6ks6Z01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.53 | 45.0 | 3.60e-01 | 93.8% | 51.7% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.53 | 39.0 | 4.43e-01 | 78.1% | 100.0% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 45.0 | 3.82e-01 | 92.2% | 79.9% |
| 1dkxA02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 29.0 | 3.52e-01 | 80.5% | 83.7% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 40.0 | 3.89e-01 | 85.2% | 72.5% |
| 6ks6a01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.52 | 44.0 | 3.48e-01 | 93.8% | 49.1% |
| 2uvaG01 | 1.20.1050.120 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 36.0 | 3.55e-01 | 70.3% | 94.1% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 42.0 | 3.92e-01 | 86.7% | 72.3% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 42.0 | 4.15e-01 | 89.1% | 92.0% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.52 | 39.0 | 3.96e-01 | 91.4% | 78.9% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 42.0 | 3.90e-01 | 88.3% | 68.9% |
| 2dkwA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.51 | 38.0 | 3.78e-01 | 82.8% | 74.8% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 38.0 | 3.65e-01 | 78.9% | 97.3% |
| 2oqhA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.50 | 36.0 | 3.77e-01 | 86.7% | 82.5% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.50 | 33.0 | 3.77e-01 | 86.7% | 88.7% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.50 | 40.0 | 3.81e-01 | 88.3% | 71.3% |
| 2l1lB00 | 1.20.1440.250 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.50 | 34.0 | 3.48e-01 | 70.3% | 89.8% |
ECOD (59)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3786622 | 109.4.1.682 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RasGEF_N | 0.65 | 45.0 | 3.64e-01 | 71.1% | 79.2% |
| 4669032 | 109.6.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF_N | 0.64 | 44.0 | 3.75e-01 | 71.1% | 78.1% |
| 4269066 | 601.54.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › low CO2-inducible protein LCI1 › low CO2-inducible protein LCI1 | 0.64 | 56.0 | 5.50e-01 | 96.1% | 97.1% |
| 3925169 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 48.0 | 4.53e-01 | 85.2% | 67.3% |
| 3918623 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.61 | 51.0 | 4.87e-01 | 88.3% | 88.3% |
| 4167072 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 50.0 | 4.08e-01 | 86.7% | 54.8% |
| 3650972 | 630.1.1.1 ↗ | a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › Rubis-subs-bind | 0.61 | 41.0 | 4.17e-01 | 71.1% | 68.5% |
| 3489229 | 5050.1.1.22 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like | 0.59 | 49.0 | 3.82e-01 | 86.7% | 73.3% |
| 4950239 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.59 | 39.0 | 4.18e-01 | 70.3% | 77.3% |
| 4840917 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.59 | 49.0 | 4.12e-01 | 89.8% | 59.0% |
| 3330173 | 5050.1.1.58 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C | 0.59 | 45.0 | 4.26e-01 | 86.7% | 66.5% |
| 4003872 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.58 | 49.0 | 4.16e-01 | 89.8% | 62.0% |
| 3225635 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.57 | 48.0 | 4.00e-01 | 89.8% | 59.1% |
| 3943936 | 150.1.1.143 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › FUSC | 0.57 | 47.0 | 4.46e-01 | 88.3% | 98.0% |
| 3800998 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.57 | 48.0 | 3.94e-01 | 90.6% | 58.3% |
| 3869802 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.57 | 47.0 | 3.76e-01 | 89.8% | 52.7% |
| 3414042 | 109.4.1.550 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARMH3_C | 0.57 | 42.0 | 2.72e-01 | 77.3% | 43.7% |
| 3575989 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.57 | 47.0 | 4.03e-01 | 89.8% | 63.5% |
| 5036855 | 140.1.1.5 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 | 0.57 | 45.0 | 3.82e-01 | 85.9% | 55.5% |
| 3584357 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.57 | 47.0 | 3.90e-01 | 89.8% | 56.5% |
| 3627661 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.57 | 47.0 | 3.97e-01 | 89.8% | 60.5% |
| 4002507 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.57 | 48.0 | 3.97e-01 | 90.6% | 62.2% |
| 3927375 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.56 | 47.0 | 3.85e-01 | 89.8% | 61.3% |
| 3788066 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.56 | 43.0 | 3.81e-01 | 79.7% | 98.9% |
| 4397663 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.56 | 47.0 | 4.06e-01 | 90.6% | 68.5% |
| 4430025 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.56 | 46.0 | 3.84e-01 | 89.8% | 56.2% |
| 4000508 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.56 | 46.0 | 3.76e-01 | 90.6% | 56.8% |
| 3939441 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.56 | 47.0 | 3.89e-01 | 90.6% | 59.6% |
| 3246412 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.56 | 46.0 | 3.73e-01 | 89.1% | 54.3% |
| 3277876 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.56 | 46.0 | 3.95e-01 | 89.8% | 66.3% |
| 3623338 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.55 | 45.0 | 3.72e-01 | 89.8% | 63.3% |
| 3617575 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.55 | 45.0 | 3.63e-01 | 89.1% | 58.1% |
| 3979691 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.55 | 46.0 | 3.88e-01 | 90.6% | 61.4% |
| 5082892 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.55 | 45.0 | 4.17e-01 | 89.8% | 73.5% |
| 5023069 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.55 | 46.0 | 4.02e-01 | 89.8% | 68.0% |
| 3965537 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.55 | 45.0 | 3.78e-01 | 89.8% | 57.8% |
| 3237268 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.55 | 45.0 | 3.81e-01 | 90.6% | 62.2% |
| 4980096 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.55 | 45.0 | 3.40e-01 | 89.1% | 99.7% |
| 3387478 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.55 | 45.0 | 3.82e-01 | 89.8% | 61.5% |
| 4938095 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.54 | 45.0 | 3.35e-01 | 89.8% | 39.7% |
| 3957616 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 46.0 | 3.72e-01 | 90.6% | 82.1% |
| 3404184 | 5067.1.1.5 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Sterol-sensing | 0.54 | 45.0 | 3.67e-01 | 89.8% | 54.7% |
| 5041595 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.54 | 45.0 | 3.88e-01 | 90.6% | 62.4% |
| 3240339 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.54 | 44.0 | 3.64e-01 | 89.8% | 63.3% |
| 3824231 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 43.0 | 3.46e-01 | 87.5% | 54.0% |
| 5020092 | 5067.1.1.4 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL | 0.54 | 44.0 | 3.71e-01 | 90.6% | 59.6% |
| 3246141 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.54 | 44.0 | 3.72e-01 | 89.8% | 65.5% |
| 3235230 | 109.22.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Survival of motor neuron protein-interacting protein 1 › Survival of motor neuron protein-interacting protein 1 › SIP1 | 0.54 | 42.0 | 3.36e-01 | 82.8% | 68.7% |
| 3334718 | 150.1.1.86 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › ZBED1_RNase-like_helical | 0.53 | 46.0 | 4.36e-01 | 92.2% | 99.3% |
| 3864427 | 593.1.1.1 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 | 0.53 | 46.0 | 3.62e-01 | 94.5% | 62.2% |
| 3629362 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.53 | 44.0 | 3.64e-01 | 88.3% | 55.6% |
| 3995665 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.53 | 44.0 | 3.45e-01 | 89.8% | 53.9% |
| 3782664 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.53 | 45.0 | 3.61e-01 | 90.6% | 59.6% |
| 3368681 | 109.4.1.935 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TOR1L1_N | 0.53 | 36.0 | 2.68e-01 | 70.3% | 41.4% |
| 3226017 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.53 | 43.0 | 3.45e-01 | 88.3% | 48.1% |
| 3939529 | 5067.1.1.3 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Patched | 0.53 | 43.0 | 3.50e-01 | 87.5% | 58.3% |
| 3235268 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.52 | 41.0 | 3.25e-01 | 84.4% | 82.9% |
| 3646445 | 3615.1.1.38 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › ROH1-like | 0.52 | 45.0 | 3.42e-01 | 96.9% | 58.2% |
| 3250076 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.50 | 38.0 | 3.74e-01 | 89.1% | 74.3% |
D4
medium
residues 471-588
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09709.16 best | Cas_Csd1 | 109.1 | 3.40e-31 | 93.2% | 19.2% |
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.66 | 54.0 | 4.04e-01 | 89.0% | 91.1% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 45.0 | 4.52e-01 | 73.7% | 95.1% |
| 4x28C03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 45.0 | 4.26e-01 | 77.1% | 93.7% |
| 2nnwA02 | 1.10.287.4070 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 41.0 | 4.05e-01 | 73.7% | 83.5% |
| 2mb9A00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.57 | 39.0 | 4.12e-01 | 70.3% | 89.6% |
| 3ddeB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.57 | 44.0 | 3.49e-01 | 100.0% | 41.6% |
| 4a25B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 40.0 | 3.66e-01 | 72.9% | 67.7% |
| 1wnvB00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.55 | 43.0 | 3.57e-01 | 82.2% | 84.3% |
| 1w36B04 | 1.10.486.10 | Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 | 0.55 | 42.0 | 3.96e-01 | 82.2% | 84.2% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.54 | 37.0 | 3.34e-01 | 71.2% | 93.9% |
| 1sk7A00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.53 | 41.0 | 3.57e-01 | 82.2% | 79.7% |
| 2ra1A01 | 1.20.58.790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 35.0 | 3.81e-01 | 72.9% | 79.6% |
| 3mzvA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 42.0 | 3.12e-01 | 83.9% | 89.3% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.53 | 39.0 | 4.01e-01 | 78.8% | 90.6% |
| 2ozbB01 | 1.10.287.4070 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 38.0 | 3.68e-01 | 73.7% | 80.2% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 35.0 | 3.74e-01 | 76.3% | 78.4% |
| 4q2cA01 | 1.10.3210.30 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › | 0.52 | 46.0 | 3.63e-01 | 100.0% | 74.9% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 40.0 | 3.75e-01 | 83.1% | 100.0% |
| 3rvyA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.52 | 39.0 | 3.96e-01 | 78.8% | 93.9% |
| 2p3yA02 | 1.10.3360.10 | Mainly Alpha › Orthogonal Bundle › VPA0735-like fold › VPA0735-like domain | 0.52 | 43.0 | 4.50e-01 | 98.3% | 100.0% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.52 | 41.0 | 3.88e-01 | 85.6% | 91.0% |
| 1n4kA02 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.51 | 33.0 | 3.11e-01 | 86.4% | 51.4% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.51 | 42.0 | 3.82e-01 | 90.7% | 86.0% |
| 2np5D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 40.0 | 3.74e-01 | 88.1% | 81.0% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5044493 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.67 | 48.0 | 4.46e-01 | 72.9% | 97.9% |
| 3319537 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.66 | 48.0 | 4.38e-01 | 74.6% | 100.0% |
| 3823125 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.65 | 47.0 | 4.38e-01 | 75.4% | 87.3% |
| 3830809 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.65 | 46.0 | 4.66e-01 | 74.6% | 95.0% |
| 3708 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.64 | 45.0 | 4.48e-01 | 73.7% | 92.8% |
| 5036841 | 5052.1.1.0 ↗ | alpha complex topology › Proton glutamate symport protein › Proton glutamate symport protein › Proton glutamate symport protein | 0.62 | 48.0 | 3.54e-01 | 80.5% | 84.6% |
| 5051451 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.62 | 42.0 | 4.71e-01 | 80.5% | 92.2% |
| 3740815 | 601.28.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 | 0.61 | 45.0 | 4.85e-01 | 82.2% | 93.9% |
| 5074120 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.61 | 43.0 | 4.67e-01 | 78.0% | 90.5% |
| 4975293 | 601.28.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 | 0.60 | 47.0 | 5.01e-01 | 83.1% | 100.0% |
| 3929825 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.60 | 43.0 | 4.34e-01 | 74.6% | 95.8% |
| 5053890 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.60 | 42.0 | 4.26e-01 | 98.3% | 73.0% |
| 3398252 | 601.4.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › NIT | 0.59 | 46.0 | 4.47e-01 | 83.1% | 89.2% |
| 5049088 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.58 | 43.0 | 4.48e-01 | 80.5% | 84.5% |
| 5053257 | 601.28.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 | 0.56 | 41.0 | 4.48e-01 | 82.2% | 96.8% |
| 5074606 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.56 | 42.0 | 4.46e-01 | 83.1% | 94.0% |
| 3466117 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.56 | 50.0 | 4.16e-01 | 99.2% | 76.1% |
| 3926669 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.55 | 36.0 | 4.21e-01 | 78.0% | 97.5% |
| 4999710 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.54 | 41.0 | 4.19e-01 | 81.4% | 86.1% |
| 3224021 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 37.0 | 2.90e-01 | 72.0% | 74.7% |
| 4949602 | 601.7.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 | 0.53 | 37.0 | 4.03e-01 | 97.5% | 88.4% |
| 1548122 | 601.43.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Biofilm formation modulator YmoB › Biofilm formation modulator YmoB › YbaJ | 0.53 | 41.0 | 4.07e-01 | 83.9% | 87.7% |
| 3601986 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.52 | 45.0 | 4.11e-01 | 99.2% | 98.2% |
| 3346760 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.51 | 33.0 | 3.23e-01 | 83.9% | 57.0% |
| 5009551 | 601.7.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PaREP1 | 0.51 | 37.0 | 3.71e-01 | 76.3% | 90.4% |
| 3596927 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 42.0 | 3.28e-01 | 89.8% | 81.2% |
| 5008391 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.50 | 35.0 | 3.42e-01 | 71.2% | 73.3% |
| 3867614 | 220.1.1.34 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_9 | 0.50 | 35.0 | 2.32e-01 | 72.0% | 33.5% |
| 3811231 | 5050.1.1.4 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nucleoside_tran | 0.50 | 44.0 | 3.88e-01 | 99.2% | 86.1% |