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helicase-1
Euk-VirEpinotia_aporema_granulovirus
helicase-1__YP_006908593__Epinotia_aporema_granulovirus__166056
Identity
- Accession:
- YP_006908593 ↗
- Protein ID:
- helicase-1
- Kingdom:
- euk
Quality
77.8
mean pLDDT
Taxonomy
TaxID: 166056
Cluster
View cluster (45 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 980-1069
Domain cluster:
rep: helicase__YP_009552640__Operophtera_brumata_nucleopolyhedrovirus__1046267__D1095-1177
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1rrmA02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.59 | 44.0 | 3.44e-01 | 80.0% | 92.0% |
| 1ks9A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.57 | 50.0 | 4.55e-01 | 100.0% | 92.7% |
| 2mhhA00 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.56 | 41.0 | 4.09e-01 | 92.2% | 72.9% |
| 1zk8B02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 40.0 | 3.57e-01 | 80.0% | 59.8% |
| 2mh9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 42.0 | 3.76e-01 | 91.1% | 82.7% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4364892 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.62 | 55.0 | 3.93e-01 | 100.0% | 62.9% |
| 4682562 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.61 | 55.0 | 4.35e-01 | 100.0% | 91.4% |
| 3240537 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.59 | 47.0 | 3.05e-01 | 90.0% | 71.3% |
| 5022761 | 304.139.1.2 ↗ | a+b two layers › Alpha-beta plaits › Cas7-related › CRISPR-associated protein Cas7/Csa2-related › RAMPs | 0.57 | 41.0 | 2.92e-01 | 75.6% | 99.3% |
| 3228469 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.56 | 39.0 | 2.78e-01 | 73.3% | 31.8% |
| 3930586 | 149.1.1.1 ↗ | alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 | 0.55 | 47.0 | 3.05e-01 | 100.0% | 84.7% |
| 4929662 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.54 | 44.0 | 3.50e-01 | 92.2% | 52.0% |
| 3650978 | 108.1.1.27 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_6 | 0.54 | 42.0 | 4.13e-01 | 84.4% | 86.0% |
| 3641759 | 141.1.1.4 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_synth_C | 0.51 | 40.0 | 2.82e-01 | 90.0% | 50.0% |
| 3519561 | 3651.1.1.0 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain | 0.50 | 41.0 | 3.71e-01 | 92.2% | 73.8% |
D2
medium
residues 14-190
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 52.6 | 2.30e-14 | 93.8% | 13.9% |
D3
medium
residues 227-374
Domain cluster:
rep: DNA-helicase-2__YP_009182280__Diatraea_saccharalis_granulovirus__1675862__D269-385
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 48.1 | 5.20e-13 | 96.6% | 11.3% |
D4
medium
residues 484-544
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1kt1A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.85 | 60.0 | 4.32e-01 | 73.8% | 29.1% |
| 2uyyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.84 | 56.0 | 4.31e-01 | 73.8% | 34.1% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.82 | 61.0 | 4.28e-01 | 80.3% | 28.0% |
| 5je8B02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.78 | 58.0 | 4.49e-01 | 78.7% | 53.9% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.76 | 65.0 | 4.81e-01 | 93.4% | 53.6% |
| 3q18A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.75 | 51.0 | 4.08e-01 | 72.1% | 37.1% |
| 2x1lA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.75 | 54.0 | 3.78e-01 | 75.4% | 36.0% |
| 1ma1A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.74 | 54.0 | 5.32e-01 | 78.7% | 79.7% |
| 1qgtB00 | 1.10.4090.10 | Mainly Alpha › Orthogonal Bundle › Hepatitis B viral capsid (hbcag) fold › Viral capsid, core domain supefamily, Hepatitis B virus | 0.72 | 51.0 | 3.88e-01 | 75.4% | 32.9% |
| 4gbjC02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.72 | 58.0 | 4.44e-01 | 86.9% | 54.1% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.67 | 48.0 | 4.35e-01 | 86.9% | 55.3% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.67 | 52.0 | 3.78e-01 | 85.2% | 69.9% |
| 1vi0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 44.0 | 3.34e-01 | 75.4% | 54.5% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.56 | 43.0 | 3.11e-01 | 86.9% | 50.5% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3603231 | 604.18.1.0 ↗ | alpha bundles › Spectrin repeat-like › Triple-helical domain in regulatory ATPase variant A (RavA) › Triple-helical domain in regulatory ATPase variant A (RavA) | 0.88 | 66.0 | 5.71e-01 | 78.7% | 53.3% |
| 3359325 | 4207.1.2.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region | 0.86 | 62.0 | 4.78e-01 | 75.4% | 36.8% |
| 4345163 | 633.10.1.28 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › PF27080 | 0.85 | 62.0 | 4.95e-01 | 77.0% | 41.7% |
| 3783023 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.84 | 62.0 | 5.12e-01 | 78.7% | 45.7% |
| 3502594 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.83 | 65.0 | 4.34e-01 | 83.6% | 24.1% |
| 4542879 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.82 | 59.0 | 4.37e-01 | 77.0% | 31.7% |
| 3961597 | 7579.1.1.62 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_8 | 0.81 | 61.0 | 3.71e-01 | 80.3% | 14.1% |
| 3518412 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.81 | 59.0 | 3.97e-01 | 78.7% | 21.8% |
| 4273807 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.80 | 62.0 | 3.64e-01 | 83.6% | 12.0% |
| 3705725 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.75 | 54.0 | 4.23e-01 | 77.0% | 40.8% |
| 3819922 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.75 | 61.0 | 4.58e-01 | 88.5% | 51.7% |
| 3218643 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.74 | 55.0 | 4.55e-01 | 78.7% | 61.0% |
| 3635635 | 3826.1.1.26 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › RRP36 | 0.74 | 56.0 | 4.18e-01 | 80.3% | 52.1% |
| 4964513 | 622.4.1.66 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › FxsA | 0.72 | 56.0 | 4.82e-01 | 83.6% | 60.0% |
| 4952876 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.70 | 51.0 | 4.55e-01 | 78.7% | 55.6% |
D5
medium
residues 545-699
Domain cluster:
rep: DNAhel-1__YP_009121868__Spodoptera_frugiperda_granulovirus__307454__D604-747
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6fmhB01 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.57 | 43.0 | 4.15e-01 | 78.1% | 86.6% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 32.0 | 3.36e-01 | 83.2% | 68.1% |
| 4zudA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 36.0 | 3.08e-01 | 72.3% | 94.1% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3057363 | 109.3.1.211 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › ANAPC5 | 0.55 | 42.0 | 4.05e-01 | 80.6% | 84.4% |
| 4977024 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.51 | 28.0 | 3.27e-01 | 89.0% | 74.5% |
D6
medium
residues 761-777_917-967
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 45.2 | 4.00e-12 | 77.9% | 3.9% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3a52A02 | 1.10.60.40 | Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › | 0.57 | 36.0 | 3.38e-01 | 75.0% | 52.9% |
| 5xkcA00 | 3.20.20.30 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain | 0.55 | 44.0 | 2.67e-01 | 88.2% | 24.7% |
| 1j1jA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.53 | 36.0 | 2.95e-01 | 70.6% | 37.1% |
| 1vq8V00 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 32.0 | 3.33e-01 | 92.6% | 67.7% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2388233 | 2002.1.1.16 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Bac_luciferase | 0.57 | 45.0 | 2.77e-01 | 88.2% | 24.3% |
| 3920800 | 1075.5.1.6 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › ANKH | 0.55 | 40.0 | 2.85e-01 | 80.9% | 70.8% |
| 3288436 | 150.5.1.11 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › T7SS_ESX_EspC | 0.53 | 33.0 | 2.90e-01 | 80.9% | 41.0% |
| 4246470 | 1075.5.1.6 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › ANKH | 0.53 | 39.0 | 2.80e-01 | 80.9% | 79.6% |
| 4208015 | 192.4.1.26 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Nlig-Ia | 0.52 | 32.0 | 3.18e-01 | 70.6% | 58.6% |
| 3279224 | 101.32.1.1 ↗ | alpha arrays › HTH › bacterioferritin-associated ferredoxin › bacterioferritin-associated ferredoxin › Fer2_BFD | 0.52 | 34.0 | 3.70e-01 | 73.5% | 83.6% |
| 4981252 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.51 | 36.0 | 3.46e-01 | 83.8% | 63.7% |