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helicase-primase_complex
Euk-VirAlcelaphine_gammaherpesvirus_1
helicase-primase_complex__NP_065539__Alcelaphine_gammaherpesvirus_1__35252
Identity
- Accession:
- NP_065539 ↗
- Protein ID:
- helicase-primase_complex
- Kingdom:
- euk
Quality
74.1
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Macavirus›
Alcelaphine_gammaherpesvirus_1
TaxID: 35252
Cluster
View cluster (3 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 46-100_112-175
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05774.17 best | Herpes_heli_pri | 120.4 | 8.40e-35 | 90.8% | 100.0% |
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4qclA05 | 1.10.132.60 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › B family DNA polymerase, thumb domain | 0.72 | 58.0 | 5.17e-01 | 86.6% | 94.0% |
| 2ondA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 44.0 | 3.24e-01 | 99.2% | 26.3% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 49.0 | 4.65e-01 | 95.8% | 70.8% |
| 5ctrA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 45.0 | 3.37e-01 | 100.0% | 31.5% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 48.0 | 4.46e-01 | 95.8% | 69.1% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.59 | 37.0 | 4.35e-01 | 84.0% | 94.9% |
| 3s64A00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.58 | 32.0 | 3.79e-01 | 77.3% | 77.8% |
| 1qrjA02 | 1.10.1200.30 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Retrovirus capsid C-terminal domain | 0.57 | 34.0 | 3.83e-01 | 89.9% | 78.8% |
| 2xgsB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.56 | 30.0 | 3.54e-01 | 92.4% | 78.1% |
| 2b1eA02 | 1.20.1310.30 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › | 0.55 | 48.0 | 4.47e-01 | 95.8% | 76.2% |
| 1sxjE03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.55 | 37.0 | 4.00e-01 | 91.6% | 84.5% |
| 4gywA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 33.0 | 3.52e-01 | 90.8% | 68.6% |
| 4gpkB01 | 1.25.40.1000 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 30.0 | 3.22e-01 | 89.9% | 61.6% |
| 1iqpA03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.53 | 34.0 | 3.69e-01 | 94.1% | 79.8% |
| 4y6cA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 37.0 | 3.10e-01 | 94.1% | 41.5% |
| 5ce8A01 | 3.30.470.10 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain | 0.52 | 29.0 | 2.90e-01 | 83.2% | 50.4% |
| 2m7bA00 | 1.10.10.1920 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.52 | 31.0 | 3.67e-01 | 79.0% | 89.6% |
| 5djsA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.52 | 35.0 | 3.29e-01 | 100.0% | 55.9% |
| 4r78A02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.52 | 40.0 | 3.49e-01 | 84.0% | 72.8% |
| 1tjcA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 33.0 | 3.60e-01 | 96.6% | 80.0% |
| 6vvoE02 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.51 | 39.0 | 4.18e-01 | 79.8% | 98.0% |
| 3q18A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 35.0 | 3.60e-01 | 92.4% | 72.4% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.51 | 39.0 | 4.10e-01 | 80.7% | 88.1% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.50 | 30.0 | 3.49e-01 | 87.4% | 90.5% |
| 2c5iT00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 35.0 | 3.90e-01 | 84.9% | 92.6% |
ECOD (36)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3469919 | 230.2.1.1 ↗ | a+b two layers › T-fold › Ribosomal protein S3-C › Ribosomal protein S3-C › Ribosomal_S3_C | 0.70 | 38.0 | 4.71e-01 | 94.1% | 85.3% |
| 4623297 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.66 | 47.0 | 4.52e-01 | 100.0% | 64.4% |
| 3789100 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 44.0 | 2.89e-01 | 100.0% | 16.7% |
| 5004518 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.62 | 39.0 | 4.64e-01 | 96.6% | 100.0% |
| 5081699 | 186.1.1.4 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_4 | 0.62 | 36.0 | 3.98e-01 | 90.8% | 73.3% |
| 3238984 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.61 | 39.0 | 4.22e-01 | 95.0% | 76.0% |
| 3213226 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.60 | 31.0 | 4.06e-01 | 95.8% | 90.8% |
| 3829197 | 109.4.1.1305 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long, TPR_24 | 0.60 | 40.0 | 3.02e-01 | 96.6% | 27.8% |
| 3711095 | 3075.1.1.0 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA | 0.59 | 31.0 | 3.84e-01 | 95.8% | 80.0% |
| 4968855 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 42.0 | 2.69e-01 | 100.0% | 14.8% |
| 3740945 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.58 | 35.0 | 4.23e-01 | 81.5% | 94.7% |
| 4984271 | 2006.1.4.2 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN | 0.57 | 36.0 | 3.47e-01 | 96.6% | 52.9% |
| 3810909 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 40.0 | 3.33e-01 | 97.5% | 41.0% |
| 3425707 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.57 | 38.0 | 2.70e-01 | 94.1% | 22.9% |
| 4998349 | 210.1.1.1 ↗ | a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome | 0.56 | 34.0 | 2.83e-01 | 92.4% | 34.1% |
| 3902172 | 109.4.1.603 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAF1_subA | 0.56 | 42.0 | 2.96e-01 | 100.0% | 23.8% |
| 3821233 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.56 | 36.0 | 4.03e-01 | 90.8% | 86.7% |
| 3715548 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.55 | 50.0 | 4.35e-01 | 100.0% | 70.0% |
| 3675555 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 43.0 | 3.53e-01 | 100.0% | 45.0% |
| 3303519 | 109.4.1.2980 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27769, PF27814 | 0.55 | 48.0 | 3.17e-01 | 100.0% | 91.0% |
| 3419838 | 109.4.1.359 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C | 0.55 | 47.0 | 3.64e-01 | 95.0% | 43.1% |
| 3391 | 138.1.1.11 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › RFC_C | 0.54 | 37.0 | 3.98e-01 | 92.4% | 83.8% |
| 4989705 | 274.1.1.0 ↗ | a+b two layers › Pili subunits › Pili subunits › Pili subunits | 0.54 | 31.0 | 3.32e-01 | 73.1% | 63.8% |
| 4997858 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.54 | 48.0 | 4.28e-01 | 98.3% | 96.5% |
| 3473725 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.54 | 34.0 | 3.82e-01 | 93.3% | 84.4% |
| 3917547 | 219.1.1.79 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 | 0.53 | 41.0 | 3.06e-01 | 83.2% | 77.6% |
| 3807070 | 109.52.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › FRIGIDA flowering-time regulator › FRIGIDA flowering-time regulator › Frigida | 0.52 | 40.0 | 3.12e-01 | 100.0% | 36.3% |
| 3669139 | 109.4.1.359 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C | 0.52 | 46.0 | 2.94e-01 | 100.0% | 27.4% |
| 3619510 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.52 | 36.0 | 3.85e-01 | 94.1% | 82.9% |
| 3194445 | 138.1.1.2 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C | 0.51 | 38.0 | 4.04e-01 | 79.0% | 96.2% |
| 4107263 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.51 | 44.0 | 4.06e-01 | 99.2% | 74.7% |
| 3232510 | 3075.1.1.1 ↗ | a+b two layers › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › ubiquitin-binding domain from PLAA › PFU | 0.51 | 28.0 | 3.36e-01 | 95.8% | 84.0% |
| 5079275 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.51 | 45.0 | 3.08e-01 | 100.0% | 82.0% |
| 3602038 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 44.0 | 2.74e-01 | 97.5% | 21.5% |
| 3412611 | 189.1.1.0 ↗ | alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP | 0.50 | 43.0 | 3.30e-01 | 95.0% | 41.4% |
| 4988469 | 212.1.1.3 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › GHMP_kinases_N | 0.50 | 38.0 | 3.44e-01 | 99.2% | 58.7% |