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helicase-primase_helicase_subunit

Euk-Vir

Cercopithecine_alphaherpesvirus_9

helicase-primase_helicase_subunit__NP_077469__Cercopithecine_alphaherpesvirus_9__35246

Identity

Accession:: NP_077469 ↗
Protein ID:: helicase-primase_helicase_subunit
Kingdom:: euk

Quality

82.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Cercopithecine_alphaherpesvirus_9

TaxID: 35246

Cluster

View cluster (90 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 332-382_792-844

PDB

Domain cluster: rep: helicase-primase_ATPase_subunit__YP_010087484__Phascolarctid_gammaherpesvirus_1__2249313__D338-366_706-759

Pfam (3)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01443.25 best	Viral_helicase1	21.6	2.40e-04	75.0%	23.2%
PF02689.21	Herpes_Helicase	82.8	2.20e-23	51.9%	6.7%
PF02689.21	Herpes_Helicase	75.1	4.80e-21	51.0%	6.3%

D2 medium residues 43-93_137-226_239-264_287-298

PDB

Domain cluster: rep: helicase_subunit__YP_009179342__Elephant_endotheliotropic_herpesvirus_4__548914__D47-64_102-182_199-230

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	80.4	1.20e-22	69.3%	13.7%
PF02689.21	Herpes_Helicase	39.2	3.40e-10	29.6%	6.2%

D3 medium residues 94-136_227-238_265-286_299-331_845-869

PDB

Domain cluster: representative

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	72.4	3.10e-20	44.4%	8.5%
PF02689.21	Herpes_Helicase	50.5	1.30e-13	38.5%	5.7%

CATH (10)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6s3eB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.65	57.0	4.98e-01	93.3%	83.9%
6jimB01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.62	52.0	5.12e-01	100.0%	82.5%
5eanA02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.57	50.0	4.32e-01	100.0%	61.8%
3ip3A01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.55	39.0	4.11e-01	74.1%	100.0%
2dcnA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.52	46.0	3.61e-01	100.0%	75.0%
3hdjA02	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.52	46.0	4.32e-01	100.0%	86.5%
2csuA02	3.40.50.261	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains	0.51	37.0	3.74e-01	75.6%	78.0%
3pl2A01	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.51	45.0	3.67e-01	98.5%	71.7%
1ufoA00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.51	44.0	3.78e-01	100.0%	79.3%
4du5B00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.51	44.0	3.49e-01	98.5%	79.0%

ECOD (15)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3567663	2004.1.1.185 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11,AAA_12	0.78	64.0	4.13e-01	85.2%	62.3%
4331804	2004.1.1.186 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12	0.64	48.0	4.25e-01	78.5%	60.0%
5024276	2004.1.1.186 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12	0.64	49.0	4.10e-01	80.7%	58.7%
4968224	2007.3.1.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains	0.58	42.0	3.94e-01	75.6%	75.3%
4943065	2007.3.1.3 ↗	a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig	0.57	41.0	3.87e-01	75.6%	75.3%
5068743	2007.3.1.3 ↗	a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Succ_CoA_lig	0.57	42.0	3.91e-01	77.0%	76.5%
5021691	2003.1.1.66 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › CoA_binding_2	0.54	40.0	4.08e-01	77.8%	96.2%
5079067	2003.1.1.29 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › OCD_Mu_crystall	0.53	47.0	4.30e-01	100.0%	83.8%
3891107	2004.1.1.186 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12	0.52	48.0	4.07e-01	99.3%	62.7%
3591005	2003.1.1.29 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › OCD_Mu_crystall	0.52	46.0	4.19e-01	100.0%	80.5%
3593770	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.52	47.0	4.02e-01	100.0%	61.9%
3605331	2004.1.1.186 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_12	0.52	47.0	4.05e-01	100.0%	62.6%
4019882	7579.1.1.99 ↗	a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4, Abhydrolase_6	0.51	45.0	3.55e-01	100.0%	81.5%
5025793	2003.1.1.29 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › OCD_Mu_crystall	0.51	46.0	4.15e-01	100.0%	79.5%
3247067	2004.1.1.184 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11	0.51	44.0	3.38e-01	100.0%	67.3%

D4 medium residues 404-478_765-789

PDB

Domain cluster: rep: helicase-primase_helicase_subunit__NP_045354__Bovine_alphaherpesvirus_1__10320__D392-469_736-760

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	72.3	3.20e-20	77.0%	9.4%

D5 medium residues 479-500_681-764

PDB

Domain cluster: rep: helicase-primase_helicase_subunit__YP_009137079__Human_alphaherpesvirus_1__10298__D496-518_696-779

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	61.4	6.40e-17	81.1%	10.2%

D6 medium residues 501-569_630-680

PDB

Domain cluster: rep: helicase-primase_helicase_subunit__YP_004940266__Saimiriine_betaherpesvirus_4__1535247__D509-572_638-677

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	53.0	2.30e-14	58.3%	7.4%
PF02689.21	Herpes_Helicase	27.5	1.20e-06	53.3%	6.8%