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helicase-primase_helicase_subunit

Euk-Vir

Beluga_whale_alphaherpesvirus_1

helicase-primase_helicase_subunit__YP_010084986__Beluga_whale_alphaherpesvirus_1__1434720

Identity

Accession:: YP_010084986 ↗
Protein ID:: helicase-primase_helicase_subunit
Kingdom:: euk

Quality

82.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Beluga_whale_alphaherpesvirus_1

TaxID: 1434720

Cluster

View cluster (90 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 64-196_230-273_287-310

PDB

Domain cluster: rep: helicase_subunit__YP_009179342__Elephant_endotheliotropic_herpesvirus_4__548914__D47-64_102-182_199-230

Pfam (3)

Accession	Name	Score	E-value	Q cov	HMM cov
PF13604.13 best	AAA_30	27.7	3.10e-06	70.2%	46.1%
PF02689.21	Herpes_Helicase	154.8	3.90e-45	67.2%	15.8%
PF02689.21	Herpes_Helicase	70.1	1.60e-19	35.3%	10.3%

D2 medium residues 274-286_311-353_838-857

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	62.9	2.20e-17	61.8%	5.3%

CATH (6)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4yxfB00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.55	46.0	3.40e-01	98.7%	76.2%
2ayiA01	3.40.1830.10	Alpha Beta › 3-Layer(aba) Sandwich › Thermophilic metalloprotease-like › Thermophilic metalloprotease (M29)	0.55	46.0	3.65e-01	98.7%	56.6%
4is2A00	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.54	45.0	3.43e-01	100.0%	64.5%
2nwqA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.53	45.0	3.34e-01	98.7%	98.6%
1xdiA01	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.51	41.0	3.11e-01	96.1%	57.8%
4dnaA01	3.50.50.60	Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain	0.50	42.0	3.04e-01	92.1%	61.0%

ECOD (13)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3720769	2004.1.1.118 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AIG1	0.55	46.0	3.16e-01	100.0%	52.4%
4019130	207.1.1.0 ↗	beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats	0.55	45.0	3.14e-01	100.0%	60.9%
10955	7590.1.1.1 ↗	a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Peptidase_M29	0.55	46.0	3.65e-01	98.7%	56.6%
4960310	7584.1.1.1 ↗	a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › AMP-binding	0.54	39.0	2.50e-01	78.9%	52.1%
3601487	2004.1.1.0 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases	0.54	42.0	2.47e-01	88.2%	20.4%
3914038	109.4.1.369 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAPC1	0.52	44.0	3.71e-01	100.0%	100.0%
5049255	2004.1.1.16 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf	0.52	42.0	3.32e-01	96.1%	91.4%
5063406	7584.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins	0.51	37.0	2.45e-01	78.9%	72.3%
2812618	7523.1.1.26 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_6	0.51	39.0	3.40e-01	98.7%	52.0%
4887943	2003.1.2.24 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox_2	0.51	42.0	3.00e-01	93.4%	63.1%
3943343	2004.1.1.208 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33	0.51	43.0	3.43e-01	100.0%	77.7%
4646556	2004.1.1.1 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA	0.51	42.0	3.28e-01	100.0%	83.1%
3659987	2007.1.3.0 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like	0.50	32.0	3.20e-01	88.2%	61.3%

D3 medium residues 354-412_780-837

PDB

Domain cluster: rep: helicase-primase_ATPase_subunit__YP_010087484__Phascolarctid_gammaherpesvirus_1__2249313__D338-366_706-759

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	86.9	1.20e-24	53.0%	7.2%
PF02689.21	Herpes_Helicase	73.6	1.40e-20	52.1%	7.3%

D4 medium residues 413-485_752-779

PDB

Domain cluster: rep: helicase-primase_helicase_subunit__NP_045354__Bovine_alphaherpesvirus_1__10320__D392-469_736-760

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	60.1	1.60e-16	73.3%	8.7%

D5 medium residues 486-506_684-751

PDB

Domain cluster: rep: helicase-primase_helicase_subunit__YP_009137079__Human_alphaherpesvirus_1__10298__D496-518_696-779

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	45.0	5.90e-12	71.9%	7.0%

D6 medium residues 507-580_630-683

PDB

Domain cluster: rep: helicase-primase_helicase_subunit__YP_004940266__Saimiriine_betaherpesvirus_4__1535247__D509-572_638-677

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02689.21 best	Herpes_Helicase	55.7	3.60e-15	60.2%	7.4%
PF02689.21	Herpes_Helicase	30.3	1.60e-07	49.2%	6.4%