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helicase-primase_helicase_subunit
Euk-VirWood_mouse_herpesvirus
helicase-primase_helicase_subunit__YP_010085918__Wood_mouse_herpesvirus__432370
Identity
- Accession:
- YP_010085918 ↗
- Protein ID:
- helicase-primase_helicase_subunit
- Kingdom:
- euk
Quality
84.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Wood_mouse_herpesvirus
TaxID: 432370
Cluster
View cluster (90 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 76-280
Domain cluster:
rep: ORF35__NP_733888__Callitrichine_gammaherpesvirus_3__106331__D45-78_114-298
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 310.1 | 4.30e-92 | 100.0% | 26.1% |
D2
medium
residues 11-75
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 75.1 | 4.90e-21 | 100.0% | 8.2% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6g1nD01 | 3.30.160.250 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.53 | 39.0 | 3.61e-01 | 100.0% | 61.4% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3225598 | 207.1.1.130 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_5, LRR_8 | 0.57 | 42.0 | 2.45e-01 | 80.0% | 11.8% |
| 4923628 | 220.1.1.14 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › DM10_dom | 0.56 | 27.0 | 2.84e-01 | 96.9% | 49.2% |
| 4002633 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.54 | 44.0 | 3.42e-01 | 90.8% | 96.0% |
| 1869479 | 3882.1.1.1 ↗ | alpha bundles › Atg17 › Atg17 › Atg17 › ATG17_like | 0.54 | 43.0 | 2.72e-01 | 92.3% | 55.7% |
D3
medium
residues 292-342_694-754
Domain cluster:
rep: helicase-primase_ATPase_subunit__YP_010087484__Phascolarctid_gammaherpesvirus_1__2249313__D338-366_706-759
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 83.9 | 1.10e-23 | 54.5% | 7.2% |
| PF02689.21 | Herpes_Helicase | 74.8 | 5.70e-21 | 46.4% | 6.3% |
D4
medium
residues 343-440_671-693
Domain cluster:
rep: helicase-primase_helicase_subunit__NP_045354__Bovine_alphaherpesvirus_1__10320__D392-469_736-760
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 103.1 | 1.60e-29 | 100.0% | 14.7% |
D5
medium
residues 441-484_559-670
Domain cluster:
rep: helicase-primase_helicase_subunit__YP_009010991__Chimpanzee_herpesvirus_strain_105640__332937__D496-582_686-776
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 120.1 | 1.10e-34 | 73.1% | 14.2% |
| PF02689.21 | Herpes_Helicase | 47.8 | 8.30e-13 | 29.5% | 5.5% |
D6
medium
residues 485-558
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 33.8 | 1.40e-08 | 100.0% | 6.4% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yzmA00 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.61 | 38.0 | 4.38e-01 | 90.5% | 100.0% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 42.0 | 3.10e-01 | 78.4% | 92.8% |
| 1qu3A04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.57 | 42.0 | 3.39e-01 | 79.7% | 62.7% |
| 1tu9A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 42.0 | 3.53e-01 | 79.7% | 65.6% |
| 1y0kA00 | 3.40.1540.10 | Alpha Beta › 3-Layer(aba) Sandwich › Hypothetical protein pa4535 › Protein of unknown function DUF1780, putative endonuclease | 0.52 | 39.0 | 3.08e-01 | 83.8% | 68.7% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4984545 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.59 | 47.0 | 4.49e-01 | 90.5% | 100.0% |
| 4011669 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.53 | 40.0 | 3.10e-01 | 79.7% | 87.9% |