helicase-primase_primase_subunit

Euk-Vir

Panine_betaherpesvirus_2

helicase-primase_primase_subunit__NP_612703__Panine_betaherpesvirus_2__188763

Identity

82.7 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Panine_betaherpesvirus_2

TaxID: 188763

View cluster (58 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 830-976

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	81.0	6.60e-23	52.4%	96.0%

CATH (9)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3bbjA00	2.40.160.210	Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain	0.54	38.0	3.19e-01	72.8%	88.8%
4h5bA00	3.30.1460.70	Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, ›	0.54	37.0	3.74e-01	74.1%	68.4%
3rqbA00	2.40.160.210	Mainly Beta › Beta Barrel › Porin › Acyl-CoA thioesterase, double hotdog domain	0.53	38.0	3.15e-01	72.8%	87.5%
2rl8A00	2.70.130.10	Mainly Beta › Distorted Sandwich › Cation-dependent Mannose-6-phosphate Receptor; Chain A › Mannose-6-phosphate receptor binding domain	0.52	40.0	4.00e-01	79.6%	85.8%
3dukA00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.52	36.0	3.88e-01	70.7%	98.4%
1zuoB00	3.10.110.10	Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme	0.52	39.0	3.98e-01	95.2%	82.1%
4r1kB00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.51	39.0	4.03e-01	79.6%	99.3%
6gh3A01	2.70.98.40	Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain	0.50	44.0	3.44e-01	95.9%	81.2%
6dnzA02	2.70.160.11	Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1	0.50	36.0	3.43e-01	74.8%	100.0%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4958461	243.3.1.0 ↗	a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin	0.61	37.0	4.59e-01	74.1%	98.9%
4348187	243.3.1.0 ↗	a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin	0.61	35.0	4.35e-01	85.7%	96.5%
3241869	216.1.1.0 ↗	a+b two layers › UBC-like › UBC-like › UBC-like	0.60	37.0	4.15e-01	100.0%	80.0%
3721374	319.1.1.0 ↗	beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones	0.60	29.0	3.40e-01	71.4%	64.0%
3620632	883.1.1.0 ↗	a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like	0.59	46.0	4.12e-01	83.7%	84.3%
5013867	243.3.1.0 ↗	a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin	0.57	32.0	4.10e-01	87.8%	96.5%
3429744	3347.1.1.2 ↗	beta meanders › Uncharacterized protein BF3112 › Uncharacterized protein BF3112 › Uncharacterized protein BF3112 › DUF1005	0.55	36.0	3.42e-01	79.6%	56.0%
3783604	222.1.1.4 ↗	a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT	0.54	39.0	3.45e-01	74.1%	81.9%
3792778	883.1.1.2 ↗	a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › LBP_BPI_CETP_C	0.53	45.0	3.18e-01	91.8%	51.5%

D2 medium residues 1-102_114-145

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162

D3 medium residues 146-252

PDB

Domain cluster: rep: helicase_primase_complex__NP_050224__Human_betaherpesvirus_6B__32604__D142-241

D4 medium residues 253-308

PDB

Domain cluster: rep: protein_UL70__YP_004933833__Cynomolgus_macaque_cytomegalovirus_strain_Ottawa__944969__D246-322

D5 medium residues 309-328_686-749

PDB

Domain cluster: representative

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4ofzA01	1.20.58.1800	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.55	42.0	3.87e-01	84.5%	84.1%
5z6bA02	3.40.190.10	Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II	0.52	41.0	3.01e-01	83.3%	78.3%
3anpB00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.52	42.0	3.28e-01	91.7%	73.2%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3591231	193.1.1.0 ↗	alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like	0.53	40.0	3.14e-01	84.5%	84.4%

D6 medium residues 364-490

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386__D431-468_522-592_634-660

D7 medium residues 491-591_667-685_750-797

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_009551869__Rhinolophus_gammaherpesvirus_1__2054179__D453-572_659-709