helicase-primase_primase_subunit

Euk-Vir

Human_alphaherpesvirus_2

helicase-primase_primase_subunit__YP_009137205__Human_alphaherpesvirus_2__10310

Identity

70.5 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Human_alphaherpesvirus_2

TaxID: 10310

View cluster (58 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 17-148_229-266

PDB

D2 high residues 913-1047

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	82.4	2.30e-23	57.0%	96.0%

D3 medium residues 267-387

PDB

D4 medium residues 428-475_515-568_608-620

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386__D431-468_522-592_634-660

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1yd0A00	3.40.1440.10	Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease	0.54	29.0	3.20e-01	81.7%	62.9%
3h20A01	3.30.1490.240	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain	0.53	25.0	3.17e-01	88.7%	75.8%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3410614	320.1.1.0 ↗	a+b two layers › R3H domain-like › R3H domain › R3H domain	0.54	30.0	3.13e-01	75.7%	57.1%

D5 medium residues 569-596_862-893

PDB

Domain cluster: representative

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6gc1A01	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.51	41.0	2.92e-01	91.7%	65.4%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3549161	109.4.1.1404 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_16	0.56	46.0	2.83e-01	98.3%	27.3%
4129499	4095.1.1.1 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_N	0.53	38.0	3.24e-01	78.3%	49.5%
3678715	109.4.1.1260 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, PPR_3, PPR_long	0.52	40.0	2.65e-01	90.0%	43.2%

D6 medium residues 621-684_763-861

PDB

Domain cluster: rep: primase__YP_009345453__Noumeavirus__1955558__D12-194