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helicase-primase_primase_subunit

Euk-Vir

Rhinolophus_gammaherpesvirus_1

helicase-primase_primase_subunit__YP_009551869__Rhinolophus_gammaherpesvirus_1__2054179

Identity

Accession:: YP_009551869 ↗
Protein ID:: helicase-primase_primase_subunit
Kingdom:: euk

Quality

87.6 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Percavirus› Rhinolophus_gammaherpesvirus_1

TaxID: 2054179

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 354-432

PDB

Domain cluster: rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D349-421

D2 high residues 741-864

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	88.1	3.90e-25	60.5%	97.3%

D3 medium residues 15-164

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162

D4 medium residues 165-260

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_401662__Human_gammaherpesvirus_4__10376__D153-223

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3nbiA01	1.10.8.1020	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain	0.73	43.0	5.51e-01	77.1%	100.0%
7zhgO01	1.10.8.50	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.60	35.0	4.00e-01	77.1%	80.3%
3ddhA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.59	36.0	3.87e-01	83.3%	71.6%
8d8lM01	1.10.8.50	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 ›	0.56	40.0	4.24e-01	99.0%	88.9%
3ltiA01	3.90.1110.10	Alpha Beta › Alpha-Beta Complex › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3 › RNA polymerase Rpb2, domain 2	0.53	42.0	3.50e-01	84.4%	77.0%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3378999	5054.1.1.8 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2	0.62	41.0	3.07e-01	100.0%	26.9%
4946426	3241.1.1.0 ↗	alpha arrays › Golgi phosphoprotein 3 › Golgi phosphoprotein 3 › Golgi phosphoprotein 3	0.57	46.0	3.61e-01	88.5%	98.1%
3584463	5054.1.1.8 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2	0.55	41.0	3.15e-01	79.2%	66.7%
3567390	150.3.1.30 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL31	0.55	39.0	3.60e-01	90.6%	57.6%
3735574	2003.1.2.16 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3,NAD_binding_8	0.51	45.0	3.19e-01	99.0%	80.9%
4606764	4041.1.1.1 ↗	a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2	0.50	42.0	3.14e-01	91.7%	76.0%

D5 medium residues 261-349_710-740

PDB

Domain cluster: rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D254-341

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5052007	1075.1.1.0 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain	0.62	38.0	2.91e-01	85.0%	25.5%
4898997	3121.1.1.1 ↗	a+b duplicates or obligate multimers › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › Polypeptide transport-associated (POTRA) domain › POTRA	0.59	23.0	2.85e-01	80.0%	54.2%
4474711	3747.1.1.2 ↗	a+b two layers › Flagellar hook protein FlgE D0 domain › Flagellar hook protein FlgE D0 domain › Flagellar hook protein FlgE D0 domain › Flg_bb_rod,Flg_bbr_C	0.54	28.0	3.02e-01	85.0%	56.2%
3169451	109.4.1.3193 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT, Suf, HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N, HAT_PRP39_N	0.53	38.0	2.36e-01	74.2%	19.2%

D6 medium residues 453-572_659-709

PDB

Domain cluster: representative

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
6kd0A01	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.52	38.0	3.13e-01	75.4%	99.7%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3694279	810.1.1.1 ↗	a+b two layers › BtrG-like (Pfam 03674) › BtrG-like (Pfam 03674) › BtrG-like (Pfam 03674) › ChaC	0.52	25.0	2.83e-01	70.8%	55.6%
3621347	304.25.1.1 ↗	a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer	0.50	31.0	3.55e-01	77.8%	85.0%

D7 medium residues 573-658

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_612703__Panine_betaherpesvirus_2__188763__D309-328_686-749

CATH (6)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2vxxA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.54	37.0	3.00e-01	72.1%	84.3%
3c2bA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.53	39.0	3.26e-01	77.9%	61.9%
3v9hD01	3.40.605.10	Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1	0.53	45.0	3.05e-01	96.5%	54.9%
3n28A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.52	40.0	3.33e-01	83.7%	94.8%
2keyA00	1.10.150.130	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain	0.51	36.0	3.32e-01	74.4%	59.8%
4ydsA00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	42.0	3.19e-01	94.2%	85.8%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3729854	109.49.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › Helical domain in acetyl-CoA carboxylase › Helical domain in acetyl-CoA carboxylase › ACC_central	0.54	37.0	2.73e-01	72.1%	50.8%
3655427	601.18.1.1 ↗	alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ	0.52	36.0	3.17e-01	72.1%	62.7%
3371755	109.4.1.1286 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12	0.51	35.0	2.98e-01	75.6%	40.0%
3781077	375.1.1.26 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2	0.51	33.0	3.16e-01	76.7%	56.3%