←Back to structures

helicase-primase_primase_subunit

Euk-Vir

Human_betaherpesvirus_7

helicase-primase_primase_subunit__YP_073783__Human_betaherpesvirus_7__10372

Identity

Accession:
YP_073783 ↗
Protein ID:
helicase-primase_primase_subunit
Kingdom:
euk

Quality

89.4 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_7

TaxID: 10372

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-148
PDB
Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162
D2 high residues 724-856
PDB
Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03121.21 best Herpes_UL52 78.1 5.10e-22 57.1% 97.3%
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4l9cA00 3.40.1000.30 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › 0.59 42.0 4.02e-01 90.2% 64.0%
1kyfA02 3.30.310.10 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein 0.57 35.0 3.71e-01 74.4% 69.0%
2joxA00 2.60.40.4240 Mainly Beta › Sandwich › Immunoglobulin-like › Transcription activator, Churchill 0.57 34.0 3.76e-01 81.2% 74.5%
3mwxA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.56 51.0 3.84e-01 100.0% 98.8%
3d2lA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.56 28.0 3.71e-01 94.7% 96.8%
4n6tA00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 33.0 4.06e-01 72.9% 100.0%
4it7A00 3.10.450.10 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 38.0 4.15e-01 72.2% 92.5%
4ggtB00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.53 39.0 4.28e-01 97.0% 97.2%
6qp7A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 41.0 2.84e-01 86.5% 59.0%
1txkA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 43.0 3.14e-01 91.0% 87.9%
3dcdA00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 46.0 3.53e-01 100.0% 96.0%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.51 36.0 3.57e-01 72.9% 80.7%
6rtqA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.50 42.0 4.25e-01 98.5% 91.0%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3581254 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.71 31.0 4.64e-01 100.0% 98.2%
3699678 897.1.1.1 ↗ a+b two layers › Acidic mitochondrial matrix protein p32-like › Acidic mitochondrial matrix protein p32 › Acidic mitochondrial matrix protein p32 › MAM33 0.68 36.0 3.17e-01 84.2% 36.8%
5010189 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.66 41.0 4.07e-01 95.5% 58.3%
4011346 3385.1.1.0 ↗ beta barrels › Allergen Alt a 1 › Allergen Alt a 1 › Allergen Alt a 1 0.59 37.0 4.45e-01 80.5% 97.6%
4028363 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.59 39.0 4.56e-01 86.5% 100.0%
3979569 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.54 41.0 4.49e-01 79.7% 95.5%
3259014 267.1.1.3 ↗ a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase 0.54 41.0 3.33e-01 80.5% 73.0%
3377087 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.53 45.0 3.22e-01 90.2% 48.4%
4354418 9.1.1.16 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.52 45.0 2.82e-01 93.2% 32.6%
3937258 220.1.1.159 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_met_RdRP 0.51 39.0 3.41e-01 80.5% 82.0%
4010689 274.1.1.0 ↗ a+b two layers › Pili subunits › Pili subunits › Pili subunits 0.51 31.0 3.52e-01 86.5% 79.0%
4065140 12.3.1.0 ↗ beta sandwiches › Glycosyl hydrolase domain-like › supersandwich › supersandwich 0.51 45.0 3.59e-01 97.7% 77.5%
4961766 241.15.1.1 ↗ a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › Spo0M 0.51 35.0 3.77e-01 72.2% 84.3%
D3 medium residues 149-218
PDB
Domain cluster: rep: helicase_primase_complex__NP_050224__Human_betaherpesvirus_6B__32604__D142-241
D4 medium residues 219-281
PDB
Domain cluster: rep: E70__YP_007016467__Murid_betaherpesvirus_8__1261657__D218-274
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jxzC02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.64 43.0 4.39e-01 71.4% 71.7%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 45.0 4.34e-01 82.5% 64.9%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.63 45.0 4.58e-01 79.4% 78.7%
4j0eA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.62 53.0 3.74e-01 96.8% 33.7%
4jylA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.62 42.0 4.64e-01 74.6% 91.8%
4jfcA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.61 42.0 4.46e-01 74.6% 82.1%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.61 45.0 4.13e-01 81.0% 69.4%
1hlvA02 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.58 38.0 3.88e-01 90.5% 70.0%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 42.0 4.03e-01 77.8% 71.2%
3sllA02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.57 40.0 4.07e-01 76.2% 100.0%
1zl8B00 1.10.287.650 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › L27 domain 0.55 41.0 4.30e-01 98.4% 94.4%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 44.0 3.84e-01 93.7% 76.5%
2hw5A02 1.10.12.10 Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 0.54 39.0 4.06e-01 79.4% 98.2%
1bxiA00 1.10.1200.20 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Colicin E immunity protein 0.52 38.0 3.51e-01 79.4% 92.8%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.52 44.0 4.06e-01 100.0% 77.9%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3822 604.4.1.1 ↗ alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP › AHSP 0.78 66.0 5.83e-01 93.7% 65.6%
4541657 547.1.1.1 ↗ alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.75 65.0 6.04e-01 98.4% 83.7%
4058838 547.1.1.1 ↗ alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.71 58.0 5.52e-01 92.1% 76.0%
3366776 109.4.1.1690 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_17, TPR_16 0.66 52.0 3.68e-01 93.7% 26.5%
5054079 192.4.1.0 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.65 45.0 4.22e-01 73.0% 60.0%
4972595 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.65 48.0 4.17e-01 82.5% 51.4%
4396464 605.1.1.305 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Exonuc_VII_S 0.64 45.0 4.65e-01 77.8% 78.3%
3222941 5054.1.1.59 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.64 51.0 3.72e-01 90.5% 81.1%
3610706 3602.1.1.0 ↗ alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.57 42.0 3.91e-01 79.4% 73.8%
3599625 109.4.1.1284 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF29978 0.53 37.0 2.73e-01 76.2% 25.6%
D5 medium residues 339-483
PDB
Domain cluster: rep: helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386__D431-468_522-592_634-660
D6 medium residues 484-547_563-699
PDB
Domain cluster: rep: helicase-primase_primase_subunit__YP_004940086__Aotine_betaherpesvirus_1__50290__D298-337_532-559_586-611_684-710_745-766