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helicase-primase_primase_subunit
Euk-VirGallid_alphaherpesvirus_1
helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386
Identity
- Accession:
- YP_182338 ↗
- Protein ID:
- helicase-primase_primase_subunit
- Kingdom:
- euk
Quality
73.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Gallid_alphaherpesvirus_1
TaxID: 10386
Cluster
View cluster (58 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 308-400
Domain cluster:
rep: helicase-primase_primase_subunit__YP_009046553__Falconid_herpesvirus_1__1510155__D359-435
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.73 | 65.0 | 5.97e-01 | 100.0% | 82.8% |
| 2y1eA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.68 | 49.0 | 5.02e-01 | 86.0% | 81.6% |
| 6wshA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.65 | 39.0 | 4.80e-01 | 81.7% | 100.0% |
| 3t4rA00 | 1.20.120.1590 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 43.0 | 4.81e-01 | 84.9% | 88.9% |
| 3rlfG01 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.65 | 47.0 | 3.32e-01 | 75.3% | 60.8% |
| 2pejA00 | 1.10.1200.210 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX | 0.63 | 43.0 | 4.11e-01 | 90.3% | 59.6% |
| 4gr6B00 | 1.10.1200.210 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX | 0.63 | 42.0 | 4.08e-01 | 87.1% | 60.0% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 36.0 | 3.79e-01 | 91.4% | 62.2% |
| 3g36B00 | 1.20.890.10 | Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | 0.62 | 34.0 | 4.29e-01 | 81.7% | 96.1% |
| 1zymA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.61 | 51.0 | 4.66e-01 | 93.5% | 77.0% |
| 2ieqA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.60 | 39.0 | 4.03e-01 | 71.0% | 69.3% |
| 3of4A00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.60 | 42.0 | 3.32e-01 | 95.7% | 33.3% |
| 2ahoB02 | 1.10.150.190 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 | 0.58 | 45.0 | 4.59e-01 | 92.5% | 85.7% |
| 1bcrA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.57 | 36.0 | 2.65e-01 | 82.8% | 22.4% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.57 | 47.0 | 4.38e-01 | 89.2% | 80.2% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.57 | 43.0 | 3.72e-01 | 80.6% | 63.9% |
| 2eh3A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 44.0 | 4.02e-01 | 82.8% | 72.1% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.56 | 49.0 | 4.34e-01 | 100.0% | 70.6% |
| 4dxwA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 40.0 | 3.82e-01 | 97.8% | 63.4% |
| 1yisA01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.55 | 46.0 | 4.51e-01 | 93.5% | 96.1% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 46.0 | 4.65e-01 | 96.8% | 96.7% |
| 2khvA01 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.54 | 38.0 | 3.97e-01 | 74.2% | 89.4% |
| 4ap9A02 | 1.10.150.210 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 | 0.53 | 28.0 | 3.38e-01 | 78.5% | 76.7% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.53 | 38.0 | 3.90e-01 | 76.3% | 80.5% |
| 1f68A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 42.0 | 4.09e-01 | 92.5% | 80.6% |
| 1kxpD02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.52 | 40.0 | 4.17e-01 | 91.4% | 90.9% |
| 4mcwA02 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.51 | 40.0 | 3.30e-01 | 89.2% | 83.4% |
| 4bw5C00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 40.0 | 3.11e-01 | 88.2% | 46.8% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.51 | 41.0 | 2.92e-01 | 89.2% | 48.5% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4028465 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.82 | 76.0 | 6.16e-01 | 100.0% | 71.3% |
| 4026470 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.81 | 75.0 | 6.24e-01 | 100.0% | 75.2% |
| 3278450 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.73 | 53.0 | 5.62e-01 | 75.3% | 98.8% |
| 4040119 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.69 | 44.0 | 4.76e-01 | 83.9% | 78.7% |
| 5077194 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.69 | 57.0 | 5.27e-01 | 90.3% | 79.0% |
| 5014639 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.68 | 59.0 | 5.77e-01 | 94.6% | 100.0% |
| 4999592 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.66 | 49.0 | 5.32e-01 | 86.0% | 100.0% |
| 3589565 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.65 | 47.0 | 3.61e-01 | 76.3% | 67.6% |
| 4464634 | 632.19.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A | 0.64 | 52.0 | 5.32e-01 | 87.1% | 100.0% |
| 4579424 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.62 | 56.0 | 4.12e-01 | 100.0% | 45.4% |
| 4002021 | 7111.1.1.1 ↗ | alpha bundles › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiq_cyt_C_chap | 0.62 | 48.0 | 3.97e-01 | 83.9% | 50.6% |
| 5025466 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.62 | 44.0 | 4.90e-01 | 84.9% | 100.0% |
| 3944793 | 601.19.1.41 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › YicC-like_C | 0.61 | 47.0 | 4.01e-01 | 82.8% | 68.4% |
| 4951280 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 50.0 | 4.07e-01 | 91.4% | 49.2% |
| 4146898 | 1037.1.1.1 ↗ | alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT | 0.61 | 53.0 | 3.83e-01 | 96.8% | 74.0% |
| 1113428 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.61 | 40.0 | 4.11e-01 | 90.3% | 69.2% |
| 4008008 | 607.1.1.1 ↗ | alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N | 0.60 | 48.0 | 4.46e-01 | 86.0% | 77.5% |
| 4681200 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.57 | 44.0 | 4.22e-01 | 83.9% | 80.9% |
| 3663611 | 5050.1.1.57 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like, NFD4_C | 0.56 | 49.0 | 3.54e-01 | 95.7% | 46.2% |
| 3880538 | 632.1.1.28 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF2678 | 0.53 | 42.0 | 4.37e-01 | 89.2% | 98.8% |
| 3630104 | 192.24.1.6 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD | 0.51 | 44.0 | 2.96e-01 | 95.7% | 31.3% |
| 3844590 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.51 | 47.0 | 4.09e-01 | 100.0% | 83.0% |
D2
high
residues 962-1106
Domain cluster:
rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03121.21 best | Herpes_UL52 | 52.5 | 5.20e-14 | 55.2% | 86.7% |
D3
medium
residues 46-222
D4
medium
residues 223-303
Domain cluster:
rep: UL52__YP_003084367__Anatid_alphaherpesvirus_1__104388__D241-302
D5
medium
residues 431-468_522-592_634-660
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2n3lA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.64 | 27.0 | 3.30e-01 | 72.1% | 58.4% |
| 7dluA03 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 26.0 | 3.32e-01 | 70.6% | 72.2% |
| 6c98A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 24.0 | 2.90e-01 | 71.3% | 59.3% |
| 1dt4A00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.51 | 25.0 | 3.17e-01 | 72.8% | 80.8% |
| 1ywhC03 | 2.10.60.10 | Mainly Beta › Ribbon › CD59 › CD59 | 0.51 | 30.0 | 3.67e-01 | 94.9% | 90.9% |
| 1jw3A00 | 3.55.10.10 | Alpha Beta › 3-Layer(bab) Sandwich › Archease, Possible Chaperone; Chain: A; domain 1 › Archease domain | 0.51 | 36.0 | 3.58e-01 | 72.1% | 93.6% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3619892 | 390.1.1.0 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like | 0.60 | 29.0 | 3.71e-01 | 98.5% | 78.7% |
| 3679321 | 256.1.1.3 ↗ | a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like › Methyltransf_29 | 0.58 | 25.0 | 2.96e-01 | 70.6% | 56.0% |
| 3453573 | 323.1.1.7 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase | 0.54 | 38.0 | 3.15e-01 | 73.5% | 81.2% |
| 3888145 | 390.1.1.4 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › MANEC | 0.53 | 30.0 | 3.51e-01 | 100.0% | 78.9% |
| 3907397 | 390.1.1.4 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › MANEC | 0.53 | 30.0 | 3.54e-01 | 98.5% | 78.9% |
| 3413058 | 382.1.1.0 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like | 0.51 | 33.0 | 3.88e-01 | 100.0% | 98.9% |
| 5033951 | 323.1.1.7 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase | 0.51 | 36.0 | 3.12e-01 | 74.3% | 92.3% |
| 3401569 | 382.1.1.14 ↗ | few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › DUF753 | 0.50 | 27.0 | 3.25e-01 | 95.6% | 80.0% |
D6
medium
residues 661-724_807-818
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1vbkA01 | 3.30.70.1510 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like | 0.71 | 49.0 | 4.77e-01 | 93.4% | 65.1% |
| 1uyjA01 | 3.30.360.60 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › | 0.68 | 48.0 | 4.67e-01 | 72.4% | 67.1% |
| 3ku7A00 | 3.30.1070.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle; Chain A › Cell division topological specificity factor MinE | 0.68 | 51.0 | 5.55e-01 | 100.0% | 100.0% |
| 4djbA00 | 3.30.70.2870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 | 0.66 | 50.0 | 4.27e-01 | 80.3% | 88.1% |
| 3uebF00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.65 | 53.0 | 4.84e-01 | 94.7% | 66.0% |
| 2e7vA01 | 3.30.70.960 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SEA domain | 0.65 | 54.0 | 4.90e-01 | 92.1% | 68.6% |
| 2y8yA01 | 3.30.70.1200 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 | 0.65 | 50.0 | 4.83e-01 | 96.1% | 73.3% |
| 3rrkA03 | 3.30.70.2750 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 42.0 | 4.30e-01 | 96.1% | 68.9% |
| 2x3gA00 | 3.30.70.1910 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 46.0 | 4.05e-01 | 94.7% | 50.9% |
| 2ej9A01 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.63 | 57.0 | 4.23e-01 | 100.0% | 63.8% |
| 2ddzE00 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.62 | 55.0 | 4.15e-01 | 100.0% | 67.4% |
| 2lu1A00 | 3.30.70.2370 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 46.0 | 4.45e-01 | 94.7% | 69.7% |
| 4wxaA00 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.62 | 41.0 | 4.04e-01 | 92.1% | 63.1% |
| 4a2aA02 | 3.30.1490.110 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › | 0.62 | 50.0 | 4.88e-01 | 92.1% | 86.2% |
| 2ckwA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.60 | 49.0 | 4.32e-01 | 92.1% | 61.2% |
| 5ao2B02 | 3.30.70.2760 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 43.0 | 4.11e-01 | 92.1% | 66.3% |
| 3encA00 | 3.30.310.50 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain | 0.59 | 42.0 | 4.15e-01 | 94.7% | 70.9% |
| 4ndhB00 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.59 | 50.0 | 3.80e-01 | 98.7% | 39.9% |
| 2a6mA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.58 | 45.0 | 3.86e-01 | 96.1% | 50.8% |
| 3ndaA01 | 3.30.497.10 | Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 | 0.57 | 39.0 | 2.76e-01 | 71.1% | 90.5% |
| 3nc3B00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.57 | 49.0 | 3.13e-01 | 96.1% | 92.5% |
| 6u6pA01 | 3.30.1070.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle; Chain A › Cell division topological specificity factor MinE | 0.57 | 48.0 | 4.81e-01 | 100.0% | 93.6% |
| 5tkwA01 | 3.30.420.380 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › | 0.56 | 39.0 | 3.07e-01 | 94.7% | 32.4% |
| 2x8kA01 | 2.40.30.200 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › | 0.56 | 47.0 | 4.25e-01 | 93.4% | 67.6% |
| 4c98A01 | 3.30.70.1890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 46.0 | 4.13e-01 | 94.7% | 64.8% |
| 5xoyB02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 45.0 | 4.10e-01 | 93.4% | 70.1% |
| 1fthA00 | 3.90.470.20 | Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain | 0.55 | 46.0 | 4.01e-01 | 92.1% | 90.6% |
| 1xdxA01 | 3.30.1140.40 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 | 0.55 | 46.0 | 4.24e-01 | 93.4% | 96.0% |
| 2joeA01 | 3.30.1830.10 | Alpha Beta › 2-Layer Sandwich › YehR-like fold › YehR-like | 0.54 | 48.0 | 4.08e-01 | 100.0% | 64.1% |
| 3znuA00 | 3.30.70.1060 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel | 0.54 | 38.0 | 3.59e-01 | 92.1% | 60.6% |
| 3il4A02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.54 | 45.0 | 3.72e-01 | 97.4% | 98.0% |
| 1fp1D02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 40.0 | 2.90e-01 | 81.6% | 93.6% |
| 2e6qA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 39.0 | 3.46e-01 | 93.4% | 53.6% |
| 3bzmA00 | 3.60.120.10 | Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase | 0.53 | 43.0 | 2.84e-01 | 98.7% | 51.7% |
| 3ccfA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 46.0 | 3.27e-01 | 100.0% | 85.3% |
| 1i72A00 | 3.60.90.10 | Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase | 0.52 | 36.0 | 2.55e-01 | 85.5% | 22.3% |
| 4fppA02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.52 | 43.0 | 3.61e-01 | 94.7% | 53.3% |
| 1bccB01 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.51 | 44.0 | 3.29e-01 | 100.0% | 41.4% |
| 4of0A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 43.0 | 3.67e-01 | 93.4% | 62.9% |
| 2jzxA02 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.51 | 38.0 | 3.77e-01 | 100.0% | 77.2% |
| 7d58G01 | 3.30.1490.120 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RNA polymerase Rpb7-like, N-terminal domain | 0.50 | 40.0 | 4.08e-01 | 92.1% | 92.0% |
ECOD (60)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4101071 | 812.1.1.1 ↗ | a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE | 0.74 | 65.0 | 6.41e-01 | 96.1% | 92.5% |
| 3591694 | 304.55.2.8 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons | 0.69 | 53.0 | 5.06e-01 | 92.1% | 70.0% |
| 3236767 | 4955.1.1.0 ↗ | a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit | 0.69 | 57.0 | 5.32e-01 | 90.8% | 80.0% |
| 4182510 | 812.1.1.1 ↗ | a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE | 0.68 | 60.0 | 5.71e-01 | 100.0% | 81.1% |
| 3796322 | 304.109.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e | 0.68 | 55.0 | 4.92e-01 | 92.1% | 62.6% |
| 3595804 | 304.55.2.0 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like | 0.68 | 52.0 | 4.89e-01 | 93.4% | 67.4% |
| 3730504 | 323.1.1.0 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases | 0.67 | 56.0 | 4.10e-01 | 94.7% | 56.8% |
| 3791442 | 872.3.1.0 ↗ | a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like | 0.67 | 55.0 | 5.18e-01 | 92.1% | 73.7% |
| 3713464 | 375.1.1.207 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › FAZ1_cons | 0.67 | 51.0 | 4.84e-01 | 92.1% | 70.0% |
| 3783593 | 246.3.1.4 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos2 | 0.67 | 59.0 | 3.74e-01 | 97.4% | 29.1% |
| 3275694 | 872.3.1.6 ↗ | a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_3 | 0.66 | 54.0 | 4.97e-01 | 93.4% | 69.0% |
| 3720046 | 304.55.2.8 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons | 0.65 | 50.0 | 4.67e-01 | 92.1% | 66.3% |
| 4318194 | 306.7.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N | 0.65 | 55.0 | 4.86e-01 | 94.7% | 91.3% |
| 4014343 | 304.18.1.0 ↗ | a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS | 0.65 | 52.0 | 4.63e-01 | 93.4% | 61.9% |
| 3922606 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.65 | 51.0 | 4.36e-01 | 92.1% | 52.8% |
| 984477 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.64 | 51.0 | 4.72e-01 | 96.1% | 67.7% |
| 3594297 | 872.3.1.5 ↗ | a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_2 | 0.64 | 51.0 | 4.83e-01 | 92.1% | 71.6% |
| 3992388 | 872.3.1.5 ↗ | a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_2 | 0.63 | 52.0 | 4.52e-01 | 93.4% | 60.0% |
| 3615120 | 375.1.1.207 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › FAZ1_cons | 0.63 | 46.0 | 4.39e-01 | 92.1% | 65.6% |
| 3940836 | 304.8.1.72 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP | 0.63 | 51.0 | 4.56e-01 | 93.4% | 62.9% |
| 3597783 | 304.55.2.8 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons | 0.63 | 45.0 | 4.09e-01 | 93.4% | 55.2% |
| 3861272 | 304.47.1.5 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › PF29544 | 0.62 | 52.0 | 4.64e-01 | 93.4% | 64.5% |
| 4469998 | 2004.1.1.429 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 | 0.62 | 43.0 | 2.78e-01 | 72.4% | 44.6% |
| 3586352 | 872.3.1.5 ↗ | a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_2 | 0.62 | 51.0 | 4.63e-01 | 93.4% | 71.4% |
| 5035799 | 304.57.1.1 ↗ | a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 | 0.61 | 50.0 | 4.34e-01 | 92.1% | 56.5% |
| 3777373 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.61 | 51.0 | 4.43e-01 | 92.1% | 59.2% |
| 3627282 | 872.3.1.0 ↗ | a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like | 0.61 | 50.0 | 4.63e-01 | 93.4% | 75.0% |
| 3701377 | 210.1.3.0 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases | 0.61 | 47.0 | 3.15e-01 | 81.6% | 61.8% |
| 4545114 | 304.162.1.1 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH | 0.61 | 36.0 | 3.55e-01 | 75.0% | 53.8% |
| 4026401 | 878.1.1.7 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Pro_sub2 | 0.61 | 48.0 | 4.37e-01 | 100.0% | 62.9% |
| 3597233 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.60 | 49.0 | 4.43e-01 | 93.4% | 65.7% |
| 3889973 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.60 | 51.0 | 4.36e-01 | 96.1% | 61.6% |
| 3188246 | 312.1.1.7 ↗ | a+b three layers › HIT-like › HIT-related › HIT-related › ATP_transf | 0.60 | 49.0 | 3.99e-01 | 100.0% | 47.6% |
| None | — | 0.59 | 44.0 | 2.80e-01 | 77.6% | 56.8% | |
| 3238197 | 862.1.1.1 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S | 0.59 | 52.0 | 4.00e-01 | 100.0% | 47.8% |
| 3588477 | 304.31.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red | 0.59 | 48.0 | 4.34e-01 | 92.1% | 63.6% |
| 2775273 | 304.51.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related | 0.58 | 47.0 | 4.03e-01 | 92.1% | 55.3% |
| 3818700 | 323.1.1.7 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase | 0.58 | 49.0 | 3.58e-01 | 98.7% | 58.3% |
| 3504252 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.58 | 46.0 | 4.36e-01 | 90.8% | 74.7% |
| 5028560 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.56 | 47.0 | 4.17e-01 | 93.4% | 68.2% |
| 3733325 | 273.1.1.1 ↗ | a+b three layers › PR-1-like › PR-1-like › PR-1-like › CAP | 0.55 | 45.0 | 3.69e-01 | 93.4% | 57.0% |
| 4949748 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.55 | 46.0 | 4.01e-01 | 96.1% | 67.2% |
| 3231858 | 304.8.1.72 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP | 0.55 | 43.0 | 3.94e-01 | 89.5% | 64.0% |
| 3636564 | 304.25.1.8 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › SGT1 | 0.55 | 47.0 | 3.51e-01 | 100.0% | 37.0% |
| 5053754 | 231.1.3.0 ↗ | a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Neutral ceramidase large domain | 0.54 | 44.0 | 2.73e-01 | 88.2% | 81.9% |
| 3934872 | 3122.1.1.2 ↗ | a+b complex topology › MESD › MESD › MESD › SCVP | 0.54 | 42.0 | 3.82e-01 | 89.5% | 61.0% |
| 1182828 | 309.1.1.0 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase | 0.54 | 41.0 | 3.09e-01 | 85.5% | 77.3% |
| 5017844 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.54 | 45.0 | 3.89e-01 | 93.4% | 66.7% |
| 3602384 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.54 | 46.0 | 3.97e-01 | 94.7% | 60.0% |
| 3213699 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.53 | 38.0 | 3.56e-01 | 93.4% | 60.0% |
| 3304087 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.53 | 41.0 | 2.58e-01 | 81.6% | 55.4% |
| 3488179 | 3501.1.1.1 ↗ | a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 | 0.53 | 35.0 | 3.37e-01 | 94.7% | 56.7% |
| 3838738 | 304.39.1.1 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd | 0.52 | 44.0 | 3.84e-01 | 98.7% | 67.2% |
| 5056633 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.52 | 47.0 | 3.54e-01 | 100.0% | 90.6% |
| 3638565 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 45.0 | 2.85e-01 | 100.0% | 21.1% |
| 3697218 | 327.11.2.35 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29984 | 0.51 | 41.0 | 4.02e-01 | 93.4% | 83.5% |
| 4520138 | 328.3.1.2 ↗ | a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain › mIF3 | 0.51 | 45.0 | 3.87e-01 | 98.7% | 90.8% |
| 3918855 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.50 | 39.0 | 3.42e-01 | 84.2% | 78.3% |
| 2388574 | 309.1.1.0 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase | 0.50 | 43.0 | 3.08e-01 | 94.7% | 67.8% |
| 3996979 | 273.1.1.0 ↗ | a+b three layers › PR-1-like › PR-1-like › PR-1-like | 0.50 | 42.0 | 3.29e-01 | 100.0% | 57.4% |