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helicase-primase_primase_subunit

Euk-Vir

Gallid_alphaherpesvirus_1

helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386

Identity

Accession:
YP_182338 ↗
Protein ID:
helicase-primase_primase_subunit
Kingdom:
euk

Quality

73.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 308-400
PDB
CATH (29)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4an8A02 1.10.132.100 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › 0.73 65.0 5.97e-01 100.0% 82.8%
2y1eA03 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.68 49.0 5.02e-01 86.0% 81.6%
6wshA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.65 39.0 4.80e-01 81.7% 100.0%
3t4rA00 1.20.120.1590 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 43.0 4.81e-01 84.9% 88.9%
3rlfG01 1.10.3720.10 Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like 0.65 47.0 3.32e-01 75.3% 60.8%
2pejA00 1.10.1200.210 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX 0.63 43.0 4.11e-01 90.3% 59.6%
4gr6B00 1.10.1200.210 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX 0.63 42.0 4.08e-01 87.1% 60.0%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 36.0 3.79e-01 91.4% 62.2%
3g36B00 1.20.890.10 Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 0.62 34.0 4.29e-01 81.7% 96.1%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.61 51.0 4.66e-01 93.5% 77.0%
2ieqA00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.60 39.0 4.03e-01 71.0% 69.3%
3of4A00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.60 42.0 3.32e-01 95.7% 33.3%
2ahoB02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.58 45.0 4.59e-01 92.5% 85.7%
1bcrA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 36.0 2.65e-01 82.8% 22.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.57 47.0 4.38e-01 89.2% 80.2%
3rv0C02 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.57 43.0 3.72e-01 80.6% 63.9%
2eh3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 44.0 4.02e-01 82.8% 72.1%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 49.0 4.34e-01 100.0% 70.6%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 40.0 3.82e-01 97.8% 63.4%
1yisA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.55 46.0 4.51e-01 93.5% 96.1%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.54 46.0 4.65e-01 96.8% 96.7%
2khvA01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.54 38.0 3.97e-01 74.2% 89.4%
4ap9A02 1.10.150.210 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 0.53 28.0 3.38e-01 78.5% 76.7%
3rguB00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.53 38.0 3.90e-01 76.3% 80.5%
1f68A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.52 42.0 4.09e-01 92.5% 80.6%
1kxpD02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.52 40.0 4.17e-01 91.4% 90.9%
4mcwA02 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.51 40.0 3.30e-01 89.2% 83.4%
4bw5C00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 40.0 3.11e-01 88.2% 46.8%
4ex8A00 3.40.1790.10 Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain 0.51 41.0 2.92e-01 89.2% 48.5%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4028465 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.82 76.0 6.16e-01 100.0% 71.3%
4026470 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.81 75.0 6.24e-01 100.0% 75.2%
3278450 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.73 53.0 5.62e-01 75.3% 98.8%
4040119 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.69 44.0 4.76e-01 83.9% 78.7%
5077194 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.69 57.0 5.27e-01 90.3% 79.0%
5014639 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.68 59.0 5.77e-01 94.6% 100.0%
4999592 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.66 49.0 5.32e-01 86.0% 100.0%
3589565 1075.3.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.65 47.0 3.61e-01 76.3% 67.6%
4464634 632.19.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A 0.64 52.0 5.32e-01 87.1% 100.0%
4579424 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.62 56.0 4.12e-01 100.0% 45.4%
4002021 7111.1.1.1 alpha bundles › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiquinol-cytochrome C chaperone, C-terminal domain › Ubiq_cyt_C_chap 0.62 48.0 3.97e-01 83.9% 50.6%
5025466 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.62 44.0 4.90e-01 84.9% 100.0%
3944793 601.19.1.41 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › YicC-like_C 0.61 47.0 4.01e-01 82.8% 68.4%
4951280 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.61 50.0 4.07e-01 91.4% 49.2%
4146898 1037.1.1.1 alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT 0.61 53.0 3.83e-01 96.8% 74.0%
1113428 5054.1.1.2 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.61 40.0 4.11e-01 90.3% 69.2%
4008008 607.1.1.1 alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N 0.60 48.0 4.46e-01 86.0% 77.5%
4681200 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.57 44.0 4.22e-01 83.9% 80.9%
3663611 5050.1.1.57 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Nodulin-like, NFD4_C 0.56 49.0 3.54e-01 95.7% 46.2%
3880538 632.1.1.28 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF2678 0.53 42.0 4.37e-01 89.2% 98.8%
3630104 192.24.1.6 alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › RNA_pol_Rpc82, HTH_9, POLR3C_WHD 0.51 44.0 2.96e-01 95.7% 31.3%
3844590 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 47.0 4.09e-01 100.0% 83.0%
D2 high residues 962-1106
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03121.21 best Herpes_UL52 52.5 5.20e-14 55.2% 86.7%
D4 medium residues 223-303
PDB
D5 medium residues 431-468_522-592_634-660
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2n3lA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 27.0 3.30e-01 72.1% 58.4%
7dluA03 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 26.0 3.32e-01 70.6% 72.2%
6c98A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 24.0 2.90e-01 71.3% 59.3%
1dt4A00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.51 25.0 3.17e-01 72.8% 80.8%
1ywhC03 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.51 30.0 3.67e-01 94.9% 90.9%
1jw3A00 3.55.10.10 Alpha Beta › 3-Layer(bab) Sandwich › Archease, Possible Chaperone; Chain: A; domain 1 › Archease domain 0.51 36.0 3.58e-01 72.1% 93.6%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3619892 390.1.1.0 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.60 29.0 3.71e-01 98.5% 78.7%
3679321 256.1.1.3 a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like › Methyltransf_29 0.58 25.0 2.96e-01 70.6% 56.0%
3453573 323.1.1.7 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.54 38.0 3.15e-01 73.5% 81.2%
3888145 390.1.1.4 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › MANEC 0.53 30.0 3.51e-01 100.0% 78.9%
3907397 390.1.1.4 few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › MANEC 0.53 30.0 3.54e-01 98.5% 78.9%
3413058 382.1.1.0 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.51 33.0 3.88e-01 100.0% 98.9%
5033951 323.1.1.7 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.51 36.0 3.12e-01 74.3% 92.3%
3401569 382.1.1.14 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › DUF753 0.50 27.0 3.25e-01 95.6% 80.0%
D6 medium residues 661-724_807-818
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vbkA01 3.30.70.1510 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like 0.71 49.0 4.77e-01 93.4% 65.1%
1uyjA01 3.30.360.60 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › 0.68 48.0 4.67e-01 72.4% 67.1%
3ku7A00 3.30.1070.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle; Chain A › Cell division topological specificity factor MinE 0.68 51.0 5.55e-01 100.0% 100.0%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.66 50.0 4.27e-01 80.3% 88.1%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.65 53.0 4.84e-01 94.7% 66.0%
2e7vA01 3.30.70.960 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SEA domain 0.65 54.0 4.90e-01 92.1% 68.6%
2y8yA01 3.30.70.1200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 0.65 50.0 4.83e-01 96.1% 73.3%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 42.0 4.30e-01 96.1% 68.9%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 46.0 4.05e-01 94.7% 50.9%
2ej9A01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.63 57.0 4.23e-01 100.0% 63.8%
2ddzE00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.62 55.0 4.15e-01 100.0% 67.4%
2lu1A00 3.30.70.2370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.45e-01 94.7% 69.7%
4wxaA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.62 41.0 4.04e-01 92.1% 63.1%
4a2aA02 3.30.1490.110 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › 0.62 50.0 4.88e-01 92.1% 86.2%
2ckwA03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.60 49.0 4.32e-01 92.1% 61.2%
5ao2B02 3.30.70.2760 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 43.0 4.11e-01 92.1% 66.3%
3encA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.59 42.0 4.15e-01 94.7% 70.9%
4ndhB00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.59 50.0 3.80e-01 98.7% 39.9%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.58 45.0 3.86e-01 96.1% 50.8%
3ndaA01 3.30.497.10 Alpha Beta › 2-Layer Sandwich › Antithrombin; Chain I, domain 2 › Antithrombin, subunit I, domain 2 0.57 39.0 2.76e-01 71.1% 90.5%
3nc3B00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.57 49.0 3.13e-01 96.1% 92.5%
6u6pA01 3.30.1070.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle; Chain A › Cell division topological specificity factor MinE 0.57 48.0 4.81e-01 100.0% 93.6%
5tkwA01 3.30.420.380 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.56 39.0 3.07e-01 94.7% 32.4%
2x8kA01 2.40.30.200 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.56 47.0 4.25e-01 93.4% 67.6%
4c98A01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 46.0 4.13e-01 94.7% 64.8%
5xoyB02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 45.0 4.10e-01 93.4% 70.1%
1fthA00 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.55 46.0 4.01e-01 92.1% 90.6%
1xdxA01 3.30.1140.40 Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › Tctex-1 0.55 46.0 4.24e-01 93.4% 96.0%
2joeA01 3.30.1830.10 Alpha Beta › 2-Layer Sandwich › YehR-like fold › YehR-like 0.54 48.0 4.08e-01 100.0% 64.1%
3znuA00 3.30.70.1060 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel 0.54 38.0 3.59e-01 92.1% 60.6%
3il4A02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.54 45.0 3.72e-01 97.4% 98.0%
1fp1D02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.53 40.0 2.90e-01 81.6% 93.6%
2e6qA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 39.0 3.46e-01 93.4% 53.6%
3bzmA00 3.60.120.10 Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase 0.53 43.0 2.84e-01 98.7% 51.7%
3ccfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.52 46.0 3.27e-01 100.0% 85.3%
1i72A00 3.60.90.10 Alpha Beta › 4-Layer Sandwich › S-adenosylmethionine decarboxylase › S-adenosylmethionine decarboxylase 0.52 36.0 2.55e-01 85.5% 22.3%
4fppA02 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.52 43.0 3.61e-01 94.7% 53.3%
1bccB01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 44.0 3.29e-01 100.0% 41.4%
4of0A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 43.0 3.67e-01 93.4% 62.9%
2jzxA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.51 38.0 3.77e-01 100.0% 77.2%
7d58G01 3.30.1490.120 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RNA polymerase Rpb7-like, N-terminal domain 0.50 40.0 4.08e-01 92.1% 92.0%
ECOD (60)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4101071 812.1.1.1 a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE 0.74 65.0 6.41e-01 96.1% 92.5%
3591694 304.55.2.8 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons 0.69 53.0 5.06e-01 92.1% 70.0%
3236767 4955.1.1.0 a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.69 57.0 5.32e-01 90.8% 80.0%
4182510 812.1.1.1 a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE 0.68 60.0 5.71e-01 100.0% 81.1%
3796322 304.109.1.0 a+b two layers › Alpha-beta plaits › Ribosomal proteins S24e, L23 and L15e › Ribosomal proteins S24e, L23 and L15e 0.68 55.0 4.92e-01 92.1% 62.6%
3595804 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.68 52.0 4.89e-01 93.4% 67.4%
3730504 323.1.1.0 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases 0.67 56.0 4.10e-01 94.7% 56.8%
3791442 872.3.1.0 a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like 0.67 55.0 5.18e-01 92.1% 73.7%
3713464 375.1.1.207 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › FAZ1_cons 0.67 51.0 4.84e-01 92.1% 70.0%
3783593 246.3.1.4 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos2 0.67 59.0 3.74e-01 97.4% 29.1%
3275694 872.3.1.6 a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_3 0.66 54.0 4.97e-01 93.4% 69.0%
3720046 304.55.2.8 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons 0.65 50.0 4.67e-01 92.1% 66.3%
4318194 306.7.1.1 a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N 0.65 55.0 4.86e-01 94.7% 91.3%
4014343 304.18.1.0 a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS 0.65 52.0 4.63e-01 93.4% 61.9%
3922606 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.65 51.0 4.36e-01 92.1% 52.8%
984477 878.1.1.1 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.64 51.0 4.72e-01 96.1% 67.7%
3594297 872.3.1.5 a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_2 0.64 51.0 4.83e-01 92.1% 71.6%
3992388 872.3.1.5 a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_2 0.63 52.0 4.52e-01 93.4% 60.0%
3615120 375.1.1.207 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › FAZ1_cons 0.63 46.0 4.39e-01 92.1% 65.6%
3940836 304.8.1.72 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP 0.63 51.0 4.56e-01 93.4% 62.9%
3597783 304.55.2.8 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons 0.63 45.0 4.09e-01 93.4% 55.2%
3861272 304.47.1.5 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › PF29544 0.62 52.0 4.64e-01 93.4% 64.5%
4469998 2004.1.1.429 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_15 0.62 43.0 2.78e-01 72.4% 44.6%
3586352 872.3.1.5 a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like › YbjQ_2 0.62 51.0 4.63e-01 93.4% 71.4%
5035799 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.61 50.0 4.34e-01 92.1% 56.5%
3777373 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.61 51.0 4.43e-01 92.1% 59.2%
3627282 872.3.1.0 a+b two layers › Dodecin subunit-like › YbjQ-like › YbjQ-like 0.61 50.0 4.63e-01 93.4% 75.0%
3701377 210.1.3.0 a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.61 47.0 3.15e-01 81.6% 61.8%
4545114 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.61 36.0 3.55e-01 75.0% 53.8%
4026401 878.1.1.7 a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Pro_sub2 0.61 48.0 4.37e-01 100.0% 62.9%
3597233 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.60 49.0 4.43e-01 93.4% 65.7%
3889973 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.60 51.0 4.36e-01 96.1% 61.6%
3188246 312.1.1.7 a+b three layers › HIT-like › HIT-related › HIT-related › ATP_transf 0.60 49.0 3.99e-01 100.0% 47.6%
None 0.59 44.0 2.80e-01 77.6% 56.8%
3238197 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.59 52.0 4.00e-01 100.0% 47.8%
3588477 304.31.1.1 a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red 0.59 48.0 4.34e-01 92.1% 63.6%
2775273 304.51.1.0 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.58 47.0 4.03e-01 92.1% 55.3%
3818700 323.1.1.7 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.58 49.0 3.58e-01 98.7% 58.3%
3504252 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.58 46.0 4.36e-01 90.8% 74.7%
5028560 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.56 47.0 4.17e-01 93.4% 68.2%
3733325 273.1.1.1 a+b three layers › PR-1-like › PR-1-like › PR-1-like › CAP 0.55 45.0 3.69e-01 93.4% 57.0%
4949748 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.55 46.0 4.01e-01 96.1% 67.2%
3231858 304.8.1.72 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP 0.55 43.0 3.94e-01 89.5% 64.0%
3636564 304.25.1.8 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › SGT1 0.55 47.0 3.51e-01 100.0% 37.0%
5053754 231.1.3.0 a+b two layers › MocoBD/DmpA-related › MocoBD/DmpA-related › Neutral ceramidase large domain 0.54 44.0 2.73e-01 88.2% 81.9%
3934872 3122.1.1.2 a+b complex topology › MESD › MESD › MESD › SCVP 0.54 42.0 3.82e-01 89.5% 61.0%
1182828 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.54 41.0 3.09e-01 85.5% 77.3%
5017844 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.54 45.0 3.89e-01 93.4% 66.7%
3602384 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.54 46.0 3.97e-01 94.7% 60.0%
3213699 327.11.2.1 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.53 38.0 3.56e-01 93.4% 60.0%
3304087 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.53 41.0 2.58e-01 81.6% 55.4%
3488179 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.53 35.0 3.37e-01 94.7% 56.7%
3838738 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.52 44.0 3.84e-01 98.7% 67.2%
5056633 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.52 47.0 3.54e-01 100.0% 90.6%
3638565 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.51 45.0 2.85e-01 100.0% 21.1%
3697218 327.11.2.35 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29984 0.51 41.0 4.02e-01 93.4% 83.5%
4520138 328.3.1.2 a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain › mIF3 0.51 45.0 3.87e-01 98.7% 90.8%
3918855 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.50 39.0 3.42e-01 84.2% 78.3%
2388574 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.50 43.0 3.08e-01 94.7% 67.8%
3996979 273.1.1.0 a+b three layers › PR-1-like › PR-1-like › PR-1-like 0.50 42.0 3.29e-01 100.0% 57.4%