helicase-primase_primase_subunit

Euk-Vir

Human_gammaherpesvirus_4

helicase-primase_primase_subunit__YP_401662__Human_gammaherpesvirus_4__10376

Identity

86.2 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Lymphocryptovirus› human_gammaherpesvirus_4

TaxID: 10376

View cluster (58 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 226-330_705-710

PDB

Domain cluster: rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D254-341

D2 high residues 489-700

PDB

Domain cluster: rep: primase__YP_009345453__Noumeavirus__1955558__D12-194

D3 high residues 717-842

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	89.9	1.10e-25	58.7%	98.7%

D4 medium residues 1-152

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162

D5 medium residues 153-223

PDB

Domain cluster: representative

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3nbiA01	1.10.8.1020	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain	0.62	39.0	4.21e-01	81.7%	77.6%
2ja2A04	1.10.8.70	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Glutamate-tRNA synthetase, class I, anticodon-binding domain 1	0.62	37.0	4.13e-01	84.5%	78.8%
3w4sA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.57	39.0	2.72e-01	71.8%	82.1%
7mcsC01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.56	37.0	2.69e-01	100.0%	22.4%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3218555	5054.1.1.0 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels	0.58	41.0	3.16e-01	83.1%	35.3%
3886806	108.1.1.28 ↗	alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_6,EF-hand_7	0.57	38.0	3.50e-01	81.7%	53.3%
3219497	103.4.1.5 ↗	alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2	0.56	41.0	4.16e-01	84.5%	78.6%
3472278	101.1.2.206 ↗	alpha arrays › HTH › HTH › winged helix domain › SAMD1_WH	0.54	35.0	3.54e-01	78.9%	62.7%
3239187	108.1.1.97 ↗	alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_7	0.52	36.0	3.50e-01	81.7%	63.7%
3866261	210.2.1.1 ↗	a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C	0.51	42.0	2.75e-01	100.0%	34.4%
3781276	190.1.1.0 ↗	alpha arrays › HMG-box-like › HMG-box › HMG-box	0.51	36.0	3.79e-01	76.1%	84.6%
4992346	102.2.1.0 ↗	alpha arrays › HhH/H2TH › H2TH › H2TH	0.50	39.0	3.87e-01	100.0%	80.0%

D6 medium residues 333-488

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386__D431-468_522-592_634-660