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helicase-primase_subunit
Euk-VirHuman_alphaherpesvirus_3
helicase-primase_subunit__NP_040174__Human_alphaherpesvirus_3__10335
Identity
- Accession:
- NP_040174 ↗
- Protein ID:
- helicase-primase_subunit
- Kingdom:
- euk
Quality
89.2
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Human_alphaherpesvirus_3
TaxID: 10335
Cluster
View cluster (61 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-153
Domain cluster:
rep: helicase-primase_subunit__YP_068368__Suid_alphaherpesvirus_1__10345__D1-121
D2
medium
residues 154-263
Domain cluster:
rep: helicase-primase_subunit__YP_001033936__Gallid_alphaherpesvirus_2__10390__D159-238
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2bs6A01 | 2.40.128.190 | Mainly Beta › Beta Barrel › Lipocalin › | 0.63 | 27.0 | 3.11e-01 | 70.0% | 50.0% |
| 3zsjA00 | 2.60.120.200 | Mainly Beta › Sandwich › Jelly Rolls › | 0.61 | 29.0 | 2.74e-01 | 70.0% | 35.5% |
| 3ke6B01 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.56 | 38.0 | 3.05e-01 | 70.9% | 51.6% |
| 2pk0A00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.53 | 36.0 | 2.80e-01 | 70.9% | 61.9% |
| 4q28A00 | 3.30.160.780 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.52 | 36.0 | 3.63e-01 | 72.7% | 70.9% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5014685 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.71 | 29.0 | 3.73e-01 | 70.0% | 63.1% |
| 4031403 | 243.3.1.72 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PF29898 | 0.67 | 27.0 | 3.99e-01 | 70.9% | 84.0% |
| 4108772 | 243.3.1.10 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › YPEB_PepSY1-2 | 0.65 | 29.0 | 3.47e-01 | 71.8% | 61.3% |
| 4945445 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.55 | 31.0 | 3.31e-01 | 71.8% | 62.8% |
| 1298174 | 260.1.1.1 ↗ | a+b duplicates or obligate multimers › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › beta-hairpin-alpha-hairpin repeat › Plectin | 0.52 | 36.0 | 3.63e-01 | 72.7% | 70.9% |
D3
medium
residues 264-357
Domain cluster:
rep: ORF40__YP_009173917__Felis_catus_gammaherpesvirus_1__1452540__D204-289
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03324.21 best | Herpes_HEPA | 68.7 | 6.50e-19 | 70.2% | 68.1% |
D4
medium
residues 358-469
Domain cluster:
representative
D5
medium
residues 470-582
Domain cluster:
rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
D6
medium
residues 583-771