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helicase-primase_subunit

Euk-Vir

Psittacid_alphaherpesvirus_1

helicase-primase_subunit__NP_944432__Psittacid_alphaherpesvirus_1__50294

Identity

Accession:
NP_944432 ↗
Protein ID:
helicase-primase_subunit
Kingdom:
euk

Quality

59.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Iltovirus› Psittacid_alphaherpesvirus_1

TaxID: 50294

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 226-431
PDB
Domain cluster: rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
D2 medium residues 432-489
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3sqgB02 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 57.0 4.23e-01 89.7% 51.7%
8gf5C01 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 56.0 4.19e-01 89.7% 54.2%
5x9vA01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.67 56.0 3.71e-01 94.8% 64.5%
5n1qB02 3.30.70.470 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 54.0 4.02e-01 89.7% 52.4%
3kd3A02 1.10.150.210 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Phosphoserine phosphatase; domain 2 0.64 43.0 4.26e-01 94.8% 66.7%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.64 46.0 4.08e-01 89.7% 54.3%
2zxqA06 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.63 45.0 4.32e-01 75.9% 84.8%
5xfaA04 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.62 46.0 4.07e-01 100.0% 54.1%
2qgnA02 1.10.287.890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain 0.62 43.0 3.83e-01 72.4% 95.1%
6hrdA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 44.0 3.05e-01 79.3% 23.0%
6ks6a01 1.10.560.10 Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain 0.60 50.0 3.31e-01 100.0% 65.0%
6q9jB02 1.20.1440.230 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain 0.59 44.0 3.83e-01 98.3% 52.3%
1kcgC00 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.58 46.0 3.50e-01 98.3% 84.1%
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.58 42.0 3.75e-01 75.9% 66.7%
3fvvA02 1.20.1440.100 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function 0.56 43.0 3.93e-01 94.8% 62.7%
1kkhA01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.56 49.0 3.51e-01 100.0% 57.5%
3kxyT00 6.20.290.10 Special › Other non-globular › Dna Ligase; domain 1 › 0.55 33.0 3.26e-01 100.0% 53.8%
1rykA00 1.10.1470.10 Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › YjbJ 0.55 38.0 3.64e-01 74.1% 63.8%
2fe1A00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.52 36.0 2.84e-01 74.1% 53.8%
3hibA01 1.10.3380.10 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain 0.50 39.0 3.21e-01 87.9% 61.0%
2wwxB00 1.20.1260.70 Mainly Alpha › Up-down Bundle › Ferritin › 0.50 43.0 3.04e-01 100.0% 45.5%
ECOD (10)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4950905 3896.1.2.6 ↗ alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-archaeol synthase › DUF92 0.66 58.0 4.34e-01 100.0% 88.0%
4367777 7523.1.1.41 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Lipoprotein_10 0.65 43.0 3.30e-01 70.7% 27.9%
3693975 186.2.1.1 ↗ alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box 0.60 49.0 3.84e-01 91.4% 56.9%
3245763 109.4.1.623 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1 0.57 49.0 2.71e-01 96.6% 8.4%
3931210 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.57 48.0 4.17e-01 100.0% 68.0%
170261 2006.1.1.14 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD 0.56 43.0 2.87e-01 94.8% 21.1%
3962529 375.1.1.15 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-CHC2 0.56 29.0 3.45e-01 79.3% 67.5%
5043647 1075.1.1.67 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › 12TM_1 0.56 47.0 3.22e-01 94.8% 82.2%
3935767 2003.6.1.1 ↗ a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like › PfkB 0.53 40.0 2.63e-01 89.7% 90.2%
3628209 5054.1.1.2 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans 0.52 46.0 2.93e-01 100.0% 74.6%
D3 medium residues 490-522_573-648
PDB