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helicase-primase_subunit
Euk-VirCercopithecine_betaherpesvirus_5
helicase-primase_subunit__YP_004936067__Cercopithecine_betaherpesvirus_5__50292
Identity
- Accession:
- YP_004936067 ↗
- Protein ID:
- helicase-primase_subunit
- Kingdom:
- euk
Quality
83.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Cytomegalovirus›
Cercopithecine_betaherpesvirus_5
TaxID: 50292
Cluster
View cluster (61 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-155
D2
medium
residues 176-334
Domain cluster:
rep: ORF31__NP_733884__Callitrichine_gammaherpesvirus_3__106331__D132-145_190-351
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03324.21 best | Herpes_HEPA | 78.8 | 4.40e-22 | 54.1% | 97.8% |
D3
medium
residues 359-400_536-547
Domain cluster:
representative
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7v6bA01 | 3.30.160.380 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Dicer dimerisation domain | 0.60 | 49.0 | 4.05e-01 | 100.0% | 77.2% |
| 5h4zA00 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.56 | 44.0 | 3.45e-01 | 92.6% | 97.7% |
| 1c7sA01 | 2.60.40.290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 39.0 | 2.95e-01 | 81.5% | 72.5% |
| 5tshA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 39.0 | 2.63e-01 | 88.9% | 35.5% |
| 5j60B02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.52 | 34.0 | 2.79e-01 | 87.0% | 31.7% |
| 7m2wE01 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.51 | 41.0 | 2.69e-01 | 100.0% | 63.5% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4877770 | 4194.1.1.3 ↗ | a+b duplicates or obligate multimers › Prenyltransferase-like › Prenyltransferase-like › Prenyltransferase-like › DUF5838 | 0.58 | 46.0 | 3.00e-01 | 92.6% | 35.1% |
| 4946272 | 4018.1.1.2 ↗ | a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › Inositol_P | 0.56 | 46.0 | 3.44e-01 | 98.1% | 89.4% |
| 3492666 | 220.1.1.151 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_MRCK | 0.55 | 42.0 | 3.86e-01 | 87.0% | 65.3% |
| 5037336 | 3665.1.1.1 ↗ | beta barrels › hypothetical protein TTMA177 › hypothetical protein TTMA177 › hypothetical protein TTMA177 › DUF6839 | 0.55 | 47.0 | 4.21e-01 | 100.0% | 91.3% |
| 4984760 | 239.5.1.1 ↗ | beta barrels › Ribosomal protein L25-like › 40S ribosomal protein S3A N-terminal domain › 40S ribosomal protein S3A N-terminal domain › Ribosomal_S3Ae | 0.54 | 37.0 | 3.25e-01 | 74.1% | 52.2% |
| 4506358 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 44.0 | 3.56e-01 | 96.3% | 76.5% |
| 3718039 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 41.0 | 2.94e-01 | 87.0% | 34.9% |
| 3984714 | 1.1.10.1 ↗ | beta barrels › cradle loop barrel › RIFT-related › Surface presentation of antigens (SPOA) › FliMN_C | 0.53 | 41.0 | 3.52e-01 | 88.9% | 74.2% |
| 3523665 | 3246.1.1.3 ↗ | few secondary structure elements › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › ADAMTS_CR_2 | 0.52 | 34.0 | 3.09e-01 | 85.2% | 45.0% |
| 3526131 | 3246.1.1.3 ↗ | few secondary structure elements › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › ADAMTS_CR_2 | 0.52 | 34.0 | 2.97e-01 | 85.2% | 42.4% |
| 3196827 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.50 | 32.0 | 2.96e-01 | 81.5% | 46.7% |
D4
medium
residues 401-474
Domain cluster:
rep: rh139__YP_068230__Macacine_betaherpesvirus_3__47929__D407-460
D5
medium
residues 475-535
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1jeyB03 | 1.10.1600.10 | Mainly Alpha › Orthogonal Bundle › Ku70; Chain: A; domain 4 › | 0.66 | 41.0 | 3.45e-01 | 72.1% | 38.2% |
| 7o4xA01 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 53.0 | 4.55e-01 | 98.4% | 67.7% |
| 6uqjA02 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.61 | 47.0 | 2.94e-01 | 83.6% | 36.8% |
| 4bgjA00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.56 | 40.0 | 3.29e-01 | 77.0% | 68.6% |
| 7r8iA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.55 | 48.0 | 3.32e-01 | 98.4% | 91.7% |
| 1tzlA02 | 3.30.1920.50 | Alpha Beta › 2-Layer Sandwich › Phage tail proteins - 2 layer sandwich fold › | 0.55 | 32.0 | 3.26e-01 | 83.6% | 56.5% |
| 3fbuA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.53 | 42.0 | 3.12e-01 | 88.5% | 74.7% |
| 3p2hA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.52 | 42.0 | 3.02e-01 | 88.5% | 75.0% |
| 3fk5A02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.52 | 38.0 | 2.96e-01 | 77.0% | 86.4% |
| 4on1A01 | 2.40.128.470 | Mainly Beta › Beta Barrel › Lipocalin › | 0.51 | 38.0 | 3.04e-01 | 86.9% | 36.7% |
| 3prbA03 | 3.30.70.2210 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 40.0 | 3.89e-01 | 93.4% | 81.1% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3391461 | 3308.2.1.1 ↗ | beta duplicates or obligate multimers › periplasmic lysozyme inhibitor of I-type lysozyme-like › XAC2610 protein › XAC2610 protein › 4_1_CTD | 0.59 | 45.0 | 4.22e-01 | 82.0% | 85.3% |
| 3364309 | 220.1.1.76 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › bPH_2 | 0.56 | 38.0 | 3.04e-01 | 72.1% | 69.2% |
| 5070432 | 314.1.1.11 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta | 0.55 | 45.0 | 3.35e-01 | 98.4% | 49.4% |
| 3224012 | 376.1.1.0 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box | 0.53 | 37.0 | 3.35e-01 | 73.8% | 65.9% |
| 3626212 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 42.0 | 3.14e-01 | 86.9% | 58.1% |
| 3605776 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.51 | 36.0 | 2.16e-01 | 75.4% | 24.9% |
| 3551510 | 60.1.2.2 ↗ | beta barrels › SPOC domain-like › SPOC domain-related › Ku70/80 subunit middle domain › Ku,Ku_C | 0.50 | 42.0 | 2.66e-01 | 93.4% | 85.8% |
D6
medium
residues 548-670_709-732
Domain cluster:
rep: E102__YP_007016498__Murid_betaherpesvirus_8__1261657__D578-728