helicase-primase_subunit

Euk-Vir

Chimpanzee_herpesvirus_strain_105640

helicase-primase_subunit__YP_009010994__Chimpanzee_herpesvirus_strain_105640__332937

Identity

90.2 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Chimpanzee_herpesvirus_strain_105640

TaxID: 332937

View cluster (61 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 612-618_620-748

PDB

Domain cluster: rep: helicase-primase_subunit__YP_009342398__Spheniscid_alphaherpesvirus_1__2560777__D627-772

D2 medium residues 1-146_230-250_272-307

PDB

Domain cluster: representative

CATH (11)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2lyxA00	3.10.450.390	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Protein of unknown function DUF3889	0.70	23.0	3.62e-01	71.9%	70.1%
2jq5A00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.58	22.0	2.80e-01	80.3%	53.9%
4gs3A00	2.40.50.140	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins	0.57	27.0	3.92e-01	70.4%	100.0%
1of5B00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.54	25.0	3.08e-01	74.4%	68.0%
3k7cA00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.52	20.0	2.71e-01	77.3%	63.0%
6lofA00	2.40.155.10	Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein	0.51	28.0	3.15e-01	96.1%	64.8%
1ar0A00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.51	23.0	2.84e-01	73.9%	66.4%
3q45A01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.50	32.0	3.90e-01	86.7%	100.0%
3hx8A00	3.10.450.50	Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, ›	0.50	24.0	2.95e-01	72.9%	68.8%
3iq2A00	3.30.1520.10	Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain	0.50	30.0	3.74e-01	76.4%	96.7%
2qddA01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.50	32.0	3.90e-01	87.2%	100.0%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3250428	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.62	30.0	3.51e-01	76.8%	63.4%
3719166	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.61	35.0	4.40e-01	70.4%	92.0%
3277627	243.1.1.0 ↗	a+b two layers › Cystatin-like › NTF2-like › NTF2-like	0.57	26.0	3.41e-01	82.3%	74.8%
152653	2.1.1.6 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB	0.57	27.0	3.92e-01	70.4%	100.0%
3965228	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.56	27.0	3.79e-01	90.1%	94.7%
4565299	243.1.1.6 ↗	a+b two layers › Cystatin-like › NTF2-like › NTF2-like › VirB8	0.52	24.0	2.86e-01	80.8%	60.4%
3785652	243.1.1.2 ↗	a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2	0.51	23.0	2.55e-01	74.9%	48.1%
3828737	243.1.1.2 ↗	a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2	0.51	24.0	3.13e-01	72.9%	75.8%
4464528	243.1.1.0 ↗	a+b two layers › Cystatin-like › NTF2-like › NTF2-like	0.51	22.0	2.90e-01	75.9%	71.6%
3289334	2.2.1.0 ↗	beta barrels › OB-fold › Bacterial enterotoxins › Bacterial enterotoxins	0.50	45.0	4.28e-01	95.6%	94.0%
5016736	11.1.1.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like	0.50	25.0	3.45e-01	88.7%	92.4%

D3 medium residues 147-229_251-271_308-352

PDB

Domain cluster: representative

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1170463	243.3.1.3 ↗	a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY	0.52	24.0	3.07e-01	71.8%	71.4%

D4 medium residues 364-384_413-479

PDB

Domain cluster: representative

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
8d3mA02	1.20.120.920	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain	0.64	46.0	3.41e-01	76.1%	59.6%
1oahA02	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.63	45.0	3.88e-01	76.1%	66.2%
4alyB00	1.10.3160.10	Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1	0.55	43.0	3.42e-01	85.2%	64.7%
2nxpB00	1.25.40.500	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TFIID subunit TAF5, NTD2 domain	0.55	39.0	3.31e-01	73.9%	78.6%
2w9yA00	1.20.120.1100	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.54	39.0	3.46e-01	93.2%	50.7%
1n8vB00	1.10.2080.10	Mainly Alpha › Orthogonal Bundle › Antennal chemosensory protein a6 › Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3	0.52	36.0	3.50e-01	98.9%	62.1%
2o71A00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.52	37.0	3.67e-01	75.0%	95.6%
2is9A01	1.10.238.10	Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand	0.51	41.0	3.85e-01	89.8%	80.5%

ECOD (4)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3302459	509.1.1.0 ↗	alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain	0.64	45.0	4.60e-01	93.2%	75.3%
3629047	192.15.1.0 ↗	alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains	0.62	45.0	4.31e-01	75.0%	94.0%
3288146	3861.1.1.1 ↗	alpha bundles › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › Mitochondrial translocator protein (TSPO) › TspO_MBR	0.59	42.0	3.62e-01	75.0%	56.4%
4927740	101.1.10.0 ↗	alpha arrays › HTH › HTH › Cyclin-like	0.52	37.0	3.30e-01	73.9%	70.0%

D5 medium residues 385-412_480-587

PDB

Domain cluster: rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289