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helicase-primase_subunit

Euk-Vir

Suid_alphaherpesvirus_1

helicase-primase_subunit__YP_068368__Suid_alphaherpesvirus_1__10345

Identity

Accession:
YP_068368 ↗
Protein ID:
helicase-primase_subunit
Kingdom:
euk

Quality

86.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Suid_alphaherpesvirus_1

TaxID: 10345

Cluster

View cluster (61 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-121
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3f14A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 31.0 3.24e-01 89.3% 51.8%
1vqqA01 3.10.450.100 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › NTF2-like; domain 1 0.60 34.0 3.54e-01 91.7% 58.7%
2jq5A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 31.0 3.10e-01 90.1% 46.9%
4gs3A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 37.0 4.22e-01 91.7% 85.6%
2f86B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 31.0 3.12e-01 90.1% 49.6%
2imjD01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 31.0 2.99e-01 83.5% 43.0%
3er7B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 32.0 3.22e-01 88.4% 52.8%
4dkmA00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.56 36.0 3.02e-01 84.3% 37.1%
1ar0A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 31.0 3.09e-01 90.1% 50.4%
3gwrB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 31.0 3.08e-01 91.7% 50.4%
5odnC00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 38.0 4.11e-01 91.7% 84.3%
3hx8A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.54 32.0 3.15e-01 88.4% 53.1%
2cc3A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.53 35.0 3.31e-01 87.6% 55.6%
4kz1A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.53 33.0 3.26e-01 90.9% 57.0%
2qddA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.52 39.0 3.82e-01 77.7% 90.0%
3h51A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 31.0 3.01e-01 89.3% 50.7%
4ibnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.52 41.0 3.63e-01 86.8% 93.6%
1jkgA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 32.0 3.08e-01 90.9% 53.2%
5aigA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 31.0 3.11e-01 95.9% 56.5%
3nv0B00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 30.0 2.90e-01 91.7% 49.3%
2bmoB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 33.0 2.84e-01 94.2% 40.2%
5i97C00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.51 32.0 3.14e-01 89.3% 55.5%
2pmqA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.50 40.0 3.96e-01 86.0% 96.9%
3gp6A00 2.40.160.20 Mainly Beta › Beta Barrel › Porin › 0.50 33.0 3.12e-01 97.5% 52.3%
3ff0A01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 31.0 3.01e-01 94.2% 52.5%
4r1kB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 34.0 3.26e-01 94.2% 61.0%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4930531 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.66 35.0 3.73e-01 75.2% 58.1%
3589048 243.1.1.7 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › MecA_N 0.62 36.0 3.49e-01 95.0% 48.6%
3225768 883.1.1.0 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like 0.61 40.0 3.55e-01 97.5% 45.9%
3280323 243.1.1.7 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › MecA_N 0.61 33.0 3.56e-01 90.9% 60.0%
3216011 243.1.1.109 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF5382, DUF5382_C 0.61 33.0 2.50e-01 90.1% 21.7%
3950757 243.1.1.7 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › MecA_N 0.61 35.0 3.60e-01 94.2% 57.4%
3217508 243.1.1.97 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF5382_N 0.59 32.0 3.24e-01 92.6% 51.2%
3466699 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.59 31.0 3.44e-01 92.6% 61.2%
152653 2.1.1.6 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › SSB 0.58 37.0 4.22e-01 91.7% 85.6%
3219090 243.1.1.47 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF5390 0.58 33.0 3.31e-01 93.4% 53.7%
3223708 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.58 33.0 3.34e-01 91.7% 55.0%
3247589 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.58 33.0 3.21e-01 91.7% 48.9%
6400 243.1.1.18 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.57 31.0 3.23e-01 86.0% 53.4%
3250428 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 37.0 3.50e-01 94.2% 54.5%
3252847 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 36.0 4.10e-01 93.4% 91.8%
3729692 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.56 35.0 3.22e-01 95.9% 47.7%
3504070 243.1.1.13 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › CaMKII_AD 0.56 34.0 3.20e-01 95.0% 50.3%
4464528 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.55 30.0 3.11e-01 91.7% 55.0%
3733425 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.55 34.0 3.28e-01 95.0% 51.7%
4978484 243.1.1.18 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.55 32.0 3.19e-01 95.9% 52.3%
3732444 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.54 33.0 3.13e-01 93.4% 49.7%
3996829 243.1.1.2 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.54 32.0 3.26e-01 87.6% 59.1%
3733248 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.53 35.0 3.25e-01 96.7% 50.0%
4565299 243.1.1.6 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › VirB8 0.53 35.0 3.32e-01 89.3% 55.6%
1562270 243.1.1.18 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.53 31.0 3.15e-01 94.2% 54.8%
3976185 243.1.1.55 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › TraE 0.53 30.0 2.79e-01 90.9% 42.0%
3798282 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.53 30.0 3.05e-01 89.3% 52.0%
6403 243.1.1.6 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › VirB8 0.53 35.0 3.34e-01 87.6% 57.1%
4978131 2484.1.1.59 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.53 39.0 3.03e-01 84.3% 34.2%
3741071 243.1.1.2 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › NTF2 0.53 30.0 2.88e-01 86.8% 46.4%
3213524 243.1.1.82 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF26529 0.52 34.0 3.19e-01 90.1% 51.6%
3991433 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.51 35.0 3.18e-01 95.9% 50.6%
3217155 243.1.1.97 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF5382_N 0.51 32.0 3.01e-01 96.7% 51.3%
3980178 7503.1.1.13 ↗ a/b three-layered sandwiches › TolB, N-terminal domain › TolB, N-terminal domain › TolB, N-terminal domain › Lipoprotein_16 0.50 36.0 3.22e-01 94.2% 51.8%
5048351 243.1.1.18 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.50 33.0 3.18e-01 93.4% 55.9%
D2 medium residues 142-307
PDB
Domain cluster: rep: helicase-primase_subunit__YP_009046502__Falconid_herpesvirus_1__1510155__D156-245_261-383
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03324.21 best Herpes_HEPA 84.1 9.90e-24 56.0% 95.6%
D3 medium residues 341-529
PDB
Domain cluster: rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
D4 medium residues 530-592_607-683
PDB
Domain cluster: rep: helicase-primase_subunit__YP_009342398__Spheniscid_alphaherpesvirus_1__2560777__D627-772