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helicase-primase_subunit

Euk-Vir

Human_betaherpesvirus_5

helicase-primase_subunit__YP_081548__Human_betaherpesvirus_5__10359

Identity

Accession:
YP_081548 ↗
Protein ID:
helicase-primase_subunit
Kingdom:
euk

Quality

71.7 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Human_betaherpesvirus_5

TaxID: 10359

Cluster

View cluster (61 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 13-166
PDB
Domain cluster: rep: helicase-primase_subunit__YP_004940263__Saimiriine_betaherpesvirus_4__1535247__D1-152
D2 medium residues 187-334
PDB
Domain cluster: rep: ORF31__NP_733884__Callitrichine_gammaherpesvirus_3__106331__D132-145_190-351
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03324.21 best Herpes_HEPA 78.3 6.60e-22 58.1% 96.7%
D3 medium residues 335-376_457-485
PDB
Domain cluster: representative
D4 medium residues 426-456_486-584
PDB
Domain cluster: representative
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2qv6B02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.73 54.0 5.57e-01 96.2% 81.1%
1s5jA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.72 68.0 6.35e-01 100.0% 93.0%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 45.0 5.49e-01 83.8% 100.0%
1d5aA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.72 60.0 5.54e-01 88.5% 86.6%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.70 40.0 5.12e-01 83.1% 100.0%
6yiiA01 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.70 64.0 5.22e-01 100.0% 63.7%
1lxjA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 49.0 5.42e-01 93.8% 92.2%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.69 44.0 4.06e-01 81.5% 49.7%
1ab8A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 64.0 5.72e-01 100.0% 79.7%
1ybtB00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 56.0 5.10e-01 98.5% 65.1%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.69 63.0 5.52e-01 100.0% 69.5%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.68 56.0 5.65e-01 86.2% 88.5%
4i0wA00 3.30.70.2980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 34.0 4.02e-01 94.6% 67.4%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.68 56.0 5.62e-01 86.2% 86.2%
6yiiA02 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.68 60.0 5.12e-01 96.9% 67.5%
2diuA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.67 39.0 4.90e-01 81.5% 100.0%
3g87A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.67 36.0 4.79e-01 80.8% 100.0%
2ahoB03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.67 45.0 5.29e-01 76.9% 100.0%
1wc1C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.67 60.0 5.28e-01 99.2% 72.9%
3v2uC02 3.30.70.3170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 47.0 5.44e-01 80.8% 100.0%
1mw7A03 3.30.70.980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain 0.67 39.0 4.90e-01 86.2% 100.0%
3r5gA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 61.0 5.28e-01 100.0% 70.3%
3dfeA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 42.0 5.05e-01 85.4% 100.0%
2w01B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 60.0 5.23e-01 100.0% 68.5%
3ungC03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 48.0 4.84e-01 95.4% 74.4%
2wz1B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 59.0 5.17e-01 99.2% 69.4%
3ezuA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 55.0 5.27e-01 100.0% 78.4%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.66 56.0 5.84e-01 93.8% 99.2%
2fyxA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.66 56.0 5.61e-01 96.9% 90.0%
4wp3C00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 56.0 4.96e-01 100.0% 64.2%
1fx2A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.66 60.0 4.88e-01 99.2% 68.5%
3hdoA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.65 39.0 3.99e-01 79.2% 60.0%
3rrkA03 3.30.70.2750 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 37.0 4.72e-01 82.3% 98.6%
3w9iA06 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.64 49.0 5.41e-01 78.5% 100.0%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 45.0 5.16e-01 84.6% 100.0%
2f1fA02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.64 35.0 4.33e-01 81.5% 87.2%
4urgA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 56.0 5.37e-01 100.0% 84.0%
4p72A04 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.63 37.0 4.61e-01 71.5% 97.4%
6eibD00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 57.0 5.36e-01 100.0% 81.4%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 56.0 5.42e-01 100.0% 86.8%
2pa8D01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.63 35.0 4.13e-01 71.5% 79.5%
2go8A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 36.0 4.62e-01 81.5% 100.0%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 55.0 5.31e-01 100.0% 84.6%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.62 41.0 4.69e-01 85.4% 91.7%
1vx4407 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 34.0 4.43e-01 78.5% 100.0%
6hbzA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 56.0 5.21e-01 100.0% 80.5%
3fotA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.62 49.0 4.02e-01 85.4% 84.5%
6d9mA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 56.0 5.38e-01 100.0% 86.8%
4cllA01 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.61 55.0 4.75e-01 100.0% 62.4%
5xgbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 56.0 5.01e-01 100.0% 72.6%
3breA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 55.0 4.91e-01 100.0% 72.6%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.61 53.0 3.83e-01 96.2% 81.6%
6ttrA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.61 55.0 4.86e-01 100.0% 69.8%
1x9mA03 3.30.70.370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 56.0 5.03e-01 100.0% 88.8%
4qmfB01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.60 36.0 4.26e-01 73.8% 92.7%
3l4gB03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.59 34.0 4.27e-01 70.0% 100.0%
2uvaG03 3.30.70.3320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 40.0 4.32e-01 80.8% 83.3%
1tuaA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.58 36.0 4.30e-01 76.2% 94.0%
1bccB01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.58 47.0 3.97e-01 84.6% 81.0%
2op5B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 42.0 4.69e-01 79.2% 100.0%
3tviA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.57 53.0 4.91e-01 100.0% 86.2%
5g4iB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 39.0 3.62e-01 73.8% 71.9%
2b9wA03 3.30.70.1990 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 38.0 4.28e-01 82.3% 100.0%
3kxyJ00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.54 34.0 3.51e-01 73.8% 64.3%
5o5cB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 38.0 3.84e-01 72.3% 95.3%
3ihgA02 3.30.9.10 Alpha Beta › 2-Layer Sandwich › D-Amino Acid Oxidase; Chain A, domain 2 › D-Amino Acid Oxidase, subunit A, domain 2 0.53 38.0 3.74e-01 88.5% 66.9%
4i6yA02 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.53 42.0 4.49e-01 91.5% 100.0%
1ivzA00 3.30.70.960 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › SEA domain 0.53 46.0 4.64e-01 98.5% 94.7%
4dmzA02 3.30.70.2880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 47.0 4.62e-01 98.5% 100.0%
8dqoB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.52 36.0 3.24e-01 72.3% 76.1%
2zbiA02 3.30.70.2120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 41.0 4.39e-01 85.4% 100.0%
3eleC01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 38.0 3.48e-01 80.0% 60.4%
ECOD (93)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4514423 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.81 46.0 6.10e-01 76.9% 100.0%
4032336 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 62.0 6.87e-01 96.2% 99.0%
4977412 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.75 56.0 5.79e-01 96.2% 82.5%
4316518 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.75 51.0 6.05e-01 79.2% 100.0%
5017083 304.48.1.3 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.75 70.0 5.39e-01 100.0% 82.6%
4572176 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.74 43.0 5.55e-01 77.7% 100.0%
4379259 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.74 60.0 6.46e-01 95.4% 100.0%
5038034 304.120.1.6 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer 0.74 50.0 6.03e-01 76.9% 100.0%
4284745 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.73 54.0 5.59e-01 95.4% 82.5%
3289139 304.48.1.6 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_A 0.73 61.0 6.48e-01 96.2% 100.0%
4061057 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.73 50.0 5.88e-01 79.2% 100.0%
4952701 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 52.0 3.76e-01 96.2% 27.9%
4956754 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.73 51.0 5.87e-01 85.4% 97.9%
5024216 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 50.0 4.54e-01 94.6% 52.6%
3958184 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.73 56.0 5.28e-01 95.4% 67.7%
5030091 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.73 47.0 5.68e-01 78.5% 100.0%
4598614 304.48.1.22 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GCH_III 0.72 51.0 5.30e-01 96.2% 78.3%
3986660 304.55.2.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.72 51.0 5.71e-01 83.8% 95.0%
5043879 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.71 48.0 5.64e-01 80.0% 100.0%
4202123 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.70 38.0 4.73e-01 70.8% 86.3%
2641638 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.70 64.0 5.27e-01 100.0% 65.6%
4987469 304.8.1.3 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NapD 0.69 38.0 4.99e-01 80.0% 100.0%
278624 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.69 56.0 5.10e-01 98.5% 65.1%
3245966 304.48.1.11 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RNA_pol 0.69 52.0 5.13e-01 79.2% 100.0%
3698765 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.69 50.0 5.46e-01 83.8% 92.4%
3999306 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.69 63.0 5.25e-01 100.0% 63.6%
4944833 304.48.1.31 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.69 57.0 5.07e-01 98.5% 63.9%
4664962 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.69 49.0 5.65e-01 93.1% 100.0%
3619500 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.68 63.0 4.69e-01 100.0% 44.4%
4978280 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.68 44.0 5.29e-01 79.2% 100.0%
4937155 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.68 42.0 5.16e-01 79.2% 100.0%
4161499 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.68 38.0 4.66e-01 71.5% 87.5%
5000514 304.19.1.1 ↗ a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.68 45.0 5.33e-01 79.2% 100.0%
4409709 304.24.1.16 ↗ a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › PrmA 0.68 48.0 5.55e-01 90.0% 100.0%
3597230 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.68 60.0 3.99e-01 97.7% 25.5%
3616629 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.68 61.0 4.89e-01 100.0% 61.9%
2641639 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.68 62.0 4.98e-01 100.0% 60.6%
4928360 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.67 61.0 5.16e-01 99.2% 72.1%
4928319 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.67 61.0 4.92e-01 99.2% 64.1%
5005078 304.48.1.113 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › mCpol 0.67 47.0 4.86e-01 82.3% 75.2%
3902327 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 61.0 4.69e-01 100.0% 46.2%
4531585 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 60.0 4.85e-01 99.2% 57.2%
4308725 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.67 61.0 5.13e-01 100.0% 62.8%
3924103 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.67 61.0 3.86e-01 100.0% 20.9%
None — 0.66 59.0 5.18e-01 98.5% 69.4%
3582031 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.66 60.0 4.96e-01 100.0% 57.0%
4217656 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.66 38.0 4.31e-01 72.3% 74.7%
None — 0.66 60.0 4.82e-01 100.0% 52.5%
4652155 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.66 60.0 5.00e-01 99.2% 62.7%
None — 0.66 60.0 3.89e-01 100.0% 22.9%
None — 0.66 60.0 3.92e-01 100.0% 23.7%
3941377 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.66 60.0 3.90e-01 100.0% 23.3%
None — 0.66 60.0 3.91e-01 100.0% 23.3%
3413344 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.66 60.0 4.90e-01 100.0% 63.7%
None — 0.66 60.0 3.98e-01 100.0% 25.7%
None — 0.66 60.0 4.00e-01 100.0% 26.5%
None — 0.66 60.0 3.94e-01 100.0% 24.9%
3876720 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 59.0 3.86e-01 100.0% 23.3%
3259574 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.65 59.0 4.92e-01 99.2% 67.1%
None — 0.65 59.0 3.96e-01 100.0% 26.7%
3241693 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 60.0 3.83e-01 100.0% 22.1%
3615056 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.65 60.0 3.96e-01 99.2% 32.0%
4929747 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.65 60.0 5.04e-01 100.0% 63.3%
3280378 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 59.0 5.42e-01 100.0% 77.0%
3938456 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 59.0 3.83e-01 100.0% 22.9%
5068007 327.19.1.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › MutL_C 0.65 37.0 4.30e-01 73.1% 78.9%
2055520 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.65 59.0 4.84e-01 100.0% 56.8%
None — 0.65 59.0 3.85e-01 100.0% 23.5%
4261006 304.48.1.11 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RNA_pol 0.65 48.0 4.54e-01 76.9% 100.0%
4024979 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 58.0 4.71e-01 99.2% 69.2%
2120642 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.65 57.0 5.65e-01 96.9% 93.5%
5004647 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.65 59.0 4.82e-01 100.0% 60.9%
3594228 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.64 58.0 4.90e-01 100.0% 66.4%
3739086 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.64 56.0 4.73e-01 97.7% 61.3%
3615693 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 58.0 4.84e-01 100.0% 65.0%
3601410 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 57.0 4.52e-01 99.2% 60.8%
3979788 304.48.1.14 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.63 56.0 5.05e-01 100.0% 72.0%
3707017 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 56.0 4.66e-01 99.2% 60.9%
1145976 304.48.1.4 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Guanylate_cyc 0.62 56.0 4.60e-01 100.0% 58.8%
4602760 3016.1.1.21 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › PDXDC1-like_cen 0.62 43.0 4.16e-01 70.0% 67.6%
3268478 3122.1.1.0 ↗ a+b complex topology › MESD › MESD › MESD 0.61 40.0 4.74e-01 77.7% 100.0%
4319282 101.1.9.5 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 0.61 37.0 4.35e-01 74.6% 87.8%
4385553 304.48.1.48 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF_2 0.59 53.0 4.89e-01 100.0% 76.4%
3470146 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.59 52.0 4.60e-01 96.2% 88.6%
3889973 304.47.1.1 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.58 50.0 5.11e-01 96.9% 96.0%
3271422 304.159.1.0 ↗ a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB 0.58 38.0 4.44e-01 74.6% 100.0%
4946875 862.1.1.1 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.57 50.0 4.00e-01 96.2% 85.7%
3813777 304.151.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase 0.57 43.0 4.70e-01 83.8% 98.1%
5054363 304.132.1.1 ↗ a+b two layers › Alpha-beta plaits › ferredoxin-like domain in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase › ferredoxin-like domain in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase › PhosphMutase 0.54 48.0 4.74e-01 97.7% 100.0%
5034659 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.53 34.0 4.00e-01 78.5% 96.5%
3521467 3016.1.1.21 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › PDXDC1-like_cen 0.53 31.0 3.66e-01 82.3% 83.3%
4991646 3281.1.1.1 ↗ alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M 0.52 40.0 2.79e-01 82.3% 56.5%
3673607 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.50 36.0 3.94e-01 75.4% 99.1%
D5 medium residues 675-734_769-798_839-873
PDB
Domain cluster: rep: E102__YP_007016498__Murid_betaherpesvirus_8__1261657__D578-728