helicase-primase_subunit

Euk-Vir

Cercopithecine_alphaherpesvirus_2

helicase-primase_subunit__YP_164450__Cercopithecine_alphaherpesvirus_2__10317

Identity

82.0 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Simplexvirus› Cercopithecine_alphaherpesvirus_2

TaxID: 10317

View cluster (61 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 590-738

PDB

Domain cluster: rep: helicase-primase_subunit__YP_009342398__Spheniscid_alphaherpesvirus_1__2560777__D627-772

D2 medium residues 1-144_232-250

PDB

Domain cluster: rep: helicase-primase_subunit__YP_004940263__Saimiriine_betaherpesvirus_4__1535247__D1-152

D3 medium residues 145-231_251-342

PDB

Domain cluster: rep: helicase-primase_subunit__YP_009046502__Falconid_herpesvirus_1__1510155__D156-245_261-383

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03324.21 best	Herpes_HEPA	70.5	1.80e-19	48.0%	74.7%

D4 medium residues 343-379_402-471

PDB

Domain cluster: rep: helicase_primase_complex_associated_protein_UL8__YP_009230138__Leporid_alphaherpesvirus_4__481315__D355-393_416-481

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2crbA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.57	33.0	3.49e-01	80.4%	63.9%
3ddhA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.56	34.0	3.82e-01	92.5%	80.2%
1fntc01	1.20.120.180	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain	0.54	37.0	3.12e-01	70.1%	93.6%
5k7fA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.53	37.0	3.48e-01	100.0%	57.2%
4dkcB00	1.20.1250.80	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-34	0.52	41.0	3.64e-01	86.0%	88.7%
1jmuB03	1.10.2050.10	Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3	0.51	36.0	3.24e-01	74.8%	93.6%
8hk0B03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.50	35.0	3.32e-01	73.8%	82.6%

ECOD (6)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5017862	601.7.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain	0.59	41.0	3.91e-01	72.0%	90.4%
3986794	639.2.1.1 ↗	alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › YmgB	0.54	33.0	3.86e-01	70.1%	92.9%
3641396	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.53	37.0	3.16e-01	72.0%	72.0%
3701510	3651.1.1.0 ↗	alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain	0.52	36.0	3.26e-01	94.4%	52.4%
3957583	103.4.1.29 ↗	alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › ABC-3	0.51	36.0	3.09e-01	73.8%	67.1%
3925082	5059.1.1.5 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA	0.50	44.0	3.33e-01	97.2%	100.0%

D5 medium residues 380-401_472-589

PDB

Domain cluster: rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289