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helicase-primase_subunit
Euk-VirGallid_alphaherpesvirus_1
helicase-primase_subunit__YP_182387__Gallid_alphaherpesvirus_1__10386
Identity
- Accession:
- YP_182387 ↗
- Protein ID:
- helicase-primase_subunit
- Kingdom:
- euk
Quality
58.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Iltovirus›
Gallid_alphaherpesvirus_1
TaxID: 10386
Cluster
View cluster (2 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-93
D2
medium
residues 105-183_267-332
D3
medium
residues 333-385
D4
medium
residues 386-411_464-491
D5
medium
residues 412-463_492-591
Domain cluster:
rep: NC_004735.1__NP_835679.1__Rm378p092__00092__D1-33_185-289
D6
medium
residues 592-670_737-795
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3f2eA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 44.0 | 5.54e-01 | 74.6% | 98.8% |
| 2xvtC00 | 1.10.150.510 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family | 0.71 | 40.0 | 5.16e-01 | 71.0% | 97.5% |
| 2q24A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 49.0 | 4.54e-01 | 81.9% | 60.7% |
| 5kbwB00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.65 | 50.0 | 4.63e-01 | 79.7% | 88.9% |
| 1s2xA00 | 1.20.190.30 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ | 0.65 | 51.0 | 4.69e-01 | 82.6% | 98.3% |
| 2vk9A04 | 1.10.274.80 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.65 | 34.0 | 3.84e-01 | 74.6% | 65.4% |
| 3i5pA03 | 1.20.120.1880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleoporin, helical C-terminal domain | 0.63 | 47.0 | 3.87e-01 | 91.3% | 43.9% |
| 4g12A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.62 | 47.0 | 4.61e-01 | 83.3% | 73.2% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.61 | 51.0 | 5.17e-01 | 97.1% | 89.2% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 48.0 | 4.73e-01 | 83.3% | 78.6% |
| 2pftA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.61 | 52.0 | 3.47e-01 | 92.0% | 31.8% |
| 5xtck00 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 34.0 | 3.98e-01 | 100.0% | 78.4% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.60 | 46.0 | 4.97e-01 | 83.3% | 97.3% |
| 4huqS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.60 | 45.0 | 4.29e-01 | 79.7% | 86.0% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 48.0 | 4.32e-01 | 85.5% | 62.8% |
| 4mo7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 45.0 | 4.53e-01 | 84.1% | 78.9% |
| 2dg8D00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 44.0 | 4.05e-01 | 79.0% | 62.4% |
| 3ejnA03 | 1.20.120.840 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SusD-like, tetratrico peptide repeats domain | 0.56 | 34.0 | 3.69e-01 | 99.3% | 72.1% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.56 | 41.0 | 4.59e-01 | 89.1% | 99.1% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 45.0 | 4.42e-01 | 95.7% | 81.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.54 | 35.0 | 3.82e-01 | 73.2% | 78.8% |
| 7smtA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.54 | 37.0 | 3.49e-01 | 71.0% | 87.9% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 39.0 | 4.37e-01 | 76.8% | 98.1% |
| 2mbgA01 | 1.10.555.10 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein | 0.53 | 41.0 | 3.69e-01 | 83.3% | 75.4% |
| 3ibvB00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 46.0 | 2.83e-01 | 97.8% | 21.0% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.52 | 44.0 | 4.43e-01 | 94.2% | 89.4% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.51 | 37.0 | 3.85e-01 | 74.6% | 81.5% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.50 | 39.0 | 3.81e-01 | 83.3% | 76.8% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4032867 | 601.1.1.11 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › EcsB | 0.74 | 61.0 | 6.10e-01 | 86.2% | 87.1% |
| 3888673 | 603.1.1.121 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30821 | 0.73 | 54.0 | 5.64e-01 | 76.1% | 100.0% |
| 3931169 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.71 | 50.0 | 5.83e-01 | 78.3% | 100.0% |
| 3599284 | 3914.1.1.0 ↗ | alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain | 0.66 | 52.0 | 3.37e-01 | 83.3% | 34.1% |
| 4264622 | 604.39.1.5 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF_trnsprt | 0.66 | 50.0 | 4.58e-01 | 79.7% | 84.7% |
| 3960608 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.66 | 48.0 | 4.99e-01 | 77.5% | 80.8% |
| 3947762 | 191.1.1.29 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_27 | 0.65 | 52.0 | 5.16e-01 | 85.5% | 81.1% |
| 5051281 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.65 | 59.0 | 5.10e-01 | 99.3% | 97.7% |
| 3951105 | 191.1.1.48 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_46 | 0.64 | 48.0 | 4.90e-01 | 85.5% | 79.0% |
| 3739076 | 109.4.1.1362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG5_C | 0.64 | 49.0 | 3.90e-01 | 80.4% | 46.7% |
| 5034580 | 3843.1.1.4 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › PhaG_MnhG_YufB | 0.63 | 33.0 | 3.85e-01 | 79.0% | 70.0% |
| 4990770 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 48.0 | 5.02e-01 | 81.2% | 96.0% |
| 3960407 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.62 | 47.0 | 4.75e-01 | 83.3% | 80.0% |
| 3274494 | 109.4.1.67 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RINT1_TIP1 | 0.61 | 53.0 | 3.53e-01 | 97.8% | 22.8% |
| 4618833 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 45.0 | 4.14e-01 | 81.9% | 59.4% |
| 3951674 | 191.1.1.26 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_24 | 0.61 | 45.0 | 4.62e-01 | 81.2% | 78.5% |
| 5010020 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.60 | 41.0 | 4.44e-01 | 97.8% | 82.6% |
| 3841137 | 109.4.1.662 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MEKK4_N | 0.60 | 46.0 | 4.01e-01 | 81.9% | 62.3% |
| 4936976 | 633.10.1.2 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Bbp7-like | 0.59 | 42.0 | 4.67e-01 | 90.6% | 95.2% |
| 4979026 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.59 | 36.0 | 3.75e-01 | 84.1% | 63.8% |
| 5018787 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.59 | 47.0 | 4.47e-01 | 85.5% | 72.1% |
| 3283447 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.58 | 44.0 | 3.88e-01 | 79.0% | 95.0% |
| 3952328 | 191.1.1.63 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_N | 0.58 | 48.0 | 4.31e-01 | 88.4% | 83.7% |
| 4957898 | 191.1.1.63 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_N | 0.58 | 46.0 | 4.11e-01 | 85.5% | 60.0% |
| 4960583 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.57 | 49.0 | 4.34e-01 | 92.0% | 88.0% |
| 3267155 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.56 | 45.0 | 4.44e-01 | 91.3% | 80.0% |
| 5014418 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 44.0 | 3.82e-01 | 84.1% | 78.6% |
| 3771070 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.55 | 44.0 | 4.24e-01 | 94.2% | 75.5% |
| 3906599 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 39.0 | 4.19e-01 | 90.6% | 87.8% |
| 3290249 | 191.1.1.33 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_31 | 0.55 | 42.0 | 4.31e-01 | 79.7% | 84.6% |
| 3708858 | 627.1.1.0 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain | 0.55 | 44.0 | 4.31e-01 | 94.2% | 79.3% |
| 4192694 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 43.0 | 3.65e-01 | 86.2% | 65.7% |
| 5041469 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.52 | 46.0 | 3.85e-01 | 95.7% | 68.1% |
| 3992989 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.52 | 38.0 | 3.73e-01 | 75.4% | 95.3% |
| 1854703 | 632.16.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › N-terminal domain of a replication restart primosome factor PriC › N-terminal domain of a replication restart primosome factor PriC › PriC | 0.52 | 41.0 | 3.84e-01 | 83.3% | 83.0% |
| 3597541 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 41.0 | 3.37e-01 | 84.8% | 80.0% |
| 4087525 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 41.0 | 3.29e-01 | 84.8% | 77.9% |
| 3183632 | 603.1.1.236 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27019 | 0.52 | 39.0 | 3.38e-01 | 79.0% | 84.5% |
| 3491802 | 109.4.1.14 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MyTH4 | 0.50 | 45.0 | 4.06e-01 | 98.6% | 78.4% |
| 3584233 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 40.0 | 3.38e-01 | 87.0% | 64.9% |