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helicase
Euk-VirChobar_Gorge_virus
helicase__YP_009158909__Chobar_Gorge_virus__1679172
Identity
- Accession:
- YP_009158909 ↗
- Protein ID:
- helicase
- Kingdom:
- euk
Quality
60.6
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Resentoviricetes›
Reovirales›
Sedoreoviridae›
Orbivirus›
Chobar_Gorge_virus
TaxID: 1679172
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 192-277
Domain cluster:
rep: VP9__YP_009345887__Orbivirus_SX-2017a__1955493__D197-270
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dnpA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.68 | 55.0 | 4.88e-01 | 89.5% | 84.6% |
| 1tezA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.63 | 49.0 | 4.40e-01 | 87.2% | 82.0% |
| 2yutA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.63 | 52.0 | 4.06e-01 | 94.2% | 90.5% |
| 4iqyB00 | 3.40.220.10 | Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 | 0.62 | 48.0 | 3.64e-01 | 84.9% | 62.1% |
| 6h99A02 | 3.40.250.10 | Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain | 0.62 | 53.0 | 4.40e-01 | 97.7% | 67.9% |
| 2yv9A01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.62 | 42.0 | 3.83e-01 | 75.6% | 54.5% |
| 3wp0A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 51.0 | 4.09e-01 | 94.2% | 90.6% |
| 3q6oA01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.61 | 41.0 | 3.58e-01 | 73.3% | 45.4% |
| 2bdtA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 51.0 | 4.13e-01 | 94.2% | 88.9% |
| 1szpB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 47.0 | 3.55e-01 | 83.7% | 55.5% |
| 1p9oA00 | 3.40.50.10300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CoaB-like | 0.61 | 44.0 | 3.12e-01 | 76.7% | 93.3% |
| 3vasA01 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.60 | 53.0 | 3.70e-01 | 98.8% | 94.3% |
| 2qorA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 49.0 | 4.39e-01 | 94.2% | 82.3% |
| 1lwdA00 | 3.40.718.10 | Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase | 0.58 | 49.0 | 3.24e-01 | 97.7% | 42.4% |
| 2r60A02 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.57 | 48.0 | 3.62e-01 | 93.0% | 98.1% |
| 4ms4B01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 48.0 | 3.57e-01 | 94.2% | 67.5% |
| 3i8oA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.56 | 49.0 | 4.35e-01 | 98.8% | 89.8% |
| 1vjtA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.56 | 45.0 | 4.12e-01 | 96.5% | 65.5% |
| 3mcwA00 | 3.40.50.850 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like | 0.56 | 48.0 | 3.69e-01 | 94.2% | 90.8% |
| 2bgwB01 | 3.40.50.10130 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 46.0 | 4.10e-01 | 93.0% | 88.5% |
| 6zb8A01 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.56 | 49.0 | 3.27e-01 | 100.0% | 48.6% |
| 4joqA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.55 | 46.0 | 3.95e-01 | 94.2% | 74.5% |
| 4eadA02 | 3.40.1030.10 | Alpha Beta › 3-Layer(aba) Sandwich › Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 › Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 0.55 | 45.0 | 3.42e-01 | 94.2% | 66.8% |
| 4ycsA00 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.54 | 45.0 | 4.03e-01 | 94.2% | 90.2% |
| 6m37B01 | 3.30.750.24 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain | 0.53 | 40.0 | 3.92e-01 | 83.7% | 81.6% |
| 6cv6D00 | 3.40.50.9100 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dehydroquinase, class II | 0.53 | 44.0 | 3.76e-01 | 94.2% | 87.5% |
| 2ziuB01 | 3.40.50.10130 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.53 | 44.0 | 3.74e-01 | 94.2% | 81.2% |
| 1mjhB00 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.52 | 40.0 | 3.53e-01 | 87.2% | 86.1% |
| 1qhhD01 | 3.30.160.800 | Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › | 0.52 | 34.0 | 3.58e-01 | 74.4% | 73.7% |
| 1eljA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.52 | 37.0 | 2.95e-01 | 75.6% | 39.9% |
| 1nv8A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 41.0 | 3.28e-01 | 90.7% | 88.8% |
| 4yleA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.52 | 43.0 | 3.76e-01 | 94.2% | 78.8% |
| 7c2xA02 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.52 | 45.0 | 3.45e-01 | 97.7% | 52.5% |
| 4ir8B02 | 3.40.190.80 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › | 0.51 | 41.0 | 3.63e-01 | 90.7% | 90.8% |
| 1nf8A00 | 3.40.50.850 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like | 0.51 | 43.0 | 3.28e-01 | 94.2% | 59.4% |
| 5isuA03 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.50 | 43.0 | 3.34e-01 | 100.0% | 75.8% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3688078 | 2004.1.1.191 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_17 | 0.69 | 58.0 | 4.53e-01 | 94.2% | 85.6% |
| 4853371 | 2005.1.1.24 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › DPRP | 0.67 | 53.0 | 4.91e-01 | 86.0% | 96.5% |
| 4929082 | 2004.1.1.260 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MEDS | 0.66 | 50.0 | 3.64e-01 | 80.2% | 52.6% |
| 3720313 | 2484.1.1.57 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ydc2-catalyt | 0.63 | 56.0 | 3.95e-01 | 100.0% | 85.1% |
| 3594882 | 2004.1.1.29 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD | 0.63 | 48.0 | 3.57e-01 | 84.9% | 48.3% |
| 4229239 | 2484.1.1.85 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC_III | 0.62 | 55.0 | 4.07e-01 | 100.0% | 88.9% |
| 3720265 | 2007.2.3.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Syja_N | 0.62 | 55.0 | 3.70e-01 | 98.8% | 80.9% |
| 5006636 | 2007.1.2.13 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I › Peripla_BP_6 | 0.62 | 43.0 | 3.19e-01 | 73.3% | 38.7% |
| 3892980 | 7510.1.1.1 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh | 0.61 | 46.0 | 4.27e-01 | 82.6% | 77.4% |
| 4025270 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.61 | 46.0 | 3.64e-01 | 80.2% | 58.7% |
| 3271830 | 7590.1.1.7 ↗ | a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › MID_MedPIWI | 0.61 | 50.0 | 3.88e-01 | 93.0% | 74.1% |
| 3402807 | 7510.1.1.1 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh | 0.61 | 52.0 | 4.37e-01 | 97.7% | 96.8% |
| 3742067 | 7516.1.1.20 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_transf_34 | 0.60 | 43.0 | 3.06e-01 | 74.4% | 68.1% |
| 3597374 | 7510.1.1.0 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like | 0.59 | 50.0 | 4.04e-01 | 96.5% | 96.1% |
| 4989268 | 2007.22.1.1 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Methyl-viologen reducing hydrogenase subunit D › Methyl-viologen reducing hydrogenase subunit D › FlpD | 0.59 | 48.0 | 4.09e-01 | 93.0% | 64.0% |
| 5063624 | 7512.1.1.3 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 | 0.58 | 48.0 | 3.50e-01 | 91.9% | 92.4% |
| 3655562 | 7510.1.1.1 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh | 0.58 | 50.0 | 3.96e-01 | 97.7% | 97.8% |
| 4021437 | 2008.1.1.0 ↗ | a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like | 0.58 | 48.0 | 3.67e-01 | 94.2% | 64.5% |
| 2600198 | 7510.1.1.1 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh | 0.57 | 50.0 | 3.99e-01 | 98.8% | 98.3% |
| 3733860 | 2006.1.1.28 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › APP1_cat | 0.57 | 47.0 | 3.33e-01 | 93.0% | 68.2% |
| 3688138 | 7573.1.1.0 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like | 0.57 | 42.0 | 4.24e-01 | 82.6% | 86.7% |
| 4096704 | 2007.1.14.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Ferrochelatase | 0.57 | 44.0 | 3.68e-01 | 87.2% | 71.8% |
| 4934254 | 2006.1.4.2 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN | 0.56 | 45.0 | 3.84e-01 | 86.0% | 89.9% |
| 4946606 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 47.0 | 3.80e-01 | 94.2% | 78.2% |
| 3300444 | 2005.1.1.0 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains | 0.56 | 43.0 | 3.93e-01 | 84.9% | 63.3% |
| 4974077 | 3008.1.1.0 ↗ | a+b three layers › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › A subdomain in the anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.56 | 42.0 | 4.07e-01 | 81.4% | 79.6% |
| 4355584 | 2007.1.14.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › Ferrochelatase | 0.55 | 43.0 | 3.35e-01 | 84.9% | 57.9% |
| 3176999 | 2006.1.4.25 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_I | 0.55 | 47.0 | 3.53e-01 | 98.8% | 79.1% |
| 3268828 | 224.1.1.0 ↗ | a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like | 0.54 | 46.0 | 4.20e-01 | 94.2% | 79.1% |
| 4875091 | 2003.1.4.9 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › SIR2_2 | 0.54 | 44.0 | 3.19e-01 | 94.2% | 88.8% |
| 3776145 | 2498.1.1.4 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin | 0.52 | 39.0 | 2.93e-01 | 80.2% | 69.1% |
| 3723851 | 129.1.1.0 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.52 | 41.0 | 3.33e-01 | 90.7% | 96.8% |
| 3469356 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.52 | 44.0 | 3.65e-01 | 97.7% | 79.4% |
| 3502798 | 2498.1.1.4 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin | 0.52 | 38.0 | 2.71e-01 | 77.9% | 60.4% |
| 3305023 | 7512.1.1.89 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT, PF26168 | 0.52 | 45.0 | 2.84e-01 | 97.7% | 25.9% |
| 3966783 | 219.1.1.77 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › DUF3335 | 0.51 | 45.0 | 3.43e-01 | 98.8% | 64.9% |
| 3871768 | 2498.1.1.4 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Reprolysin | 0.51 | 38.0 | 2.72e-01 | 79.1% | 73.6% |
D2
medium
residues 1-29_280-346
Domain cluster:
rep: helicase__YP_008719929__Changuinola_virus__40052__D4-32_215-282
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01516.23 best | Orbi_VP6 | 47.7 | 2.50e-12 | 72.9% | 19.6% |