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helicase
Euk-VirOperophtera_brumata_nucleopolyhedrovirus
helicase__YP_009552640__Operophtera_brumata_nucleopolyhedrovirus__1046267
Identity
- Accession:
- YP_009552640 ↗
- Protein ID:
- helicase
- Kingdom:
- euk
Quality
71.1
mean pLDDT
Taxonomy
Naldaviricetes›
Lefavirales›
Baculoviridae›
Alphabaculovirus›
Operophtera_brumata_nucleopolyhedrovirus
TaxID: 1046267
Cluster
View cluster (45 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-61_81-91
Domain cluster:
rep: helicase__YP_009666576__Oxyplax_ochracea_nucleopolyhedrovirus__2083176__D1-61_84-94
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1i8nA00 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.62 | 50.0 | 4.71e-01 | 90.3% | 76.4% |
| 2h5eA03 | 3.30.70.3280 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Peptide chain release factor 3, domain III | 0.60 | 46.0 | 3.69e-01 | 81.9% | 94.9% |
| 2k13X00 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.57 | 46.0 | 4.15e-01 | 93.1% | 75.7% |
| 3rjaA02 | 3.40.462.20 | Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › | 0.56 | 42.0 | 3.03e-01 | 81.9% | 63.8% |
| 1w8kA02 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.55 | 46.0 | 4.04e-01 | 94.4% | 68.2% |
| 6f95A01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.54 | 45.0 | 3.63e-01 | 95.8% | 90.5% |
| 2m88A01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.53 | 37.0 | 3.58e-01 | 76.4% | 90.7% |
| 1gmnA01 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.53 | 43.0 | 4.04e-01 | 90.3% | 83.0% |
| 4c23B02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 40.0 | 2.82e-01 | 83.3% | 85.5% |
| 2xqyA03 | 2.60.40.3190 | Mainly Beta › Sandwich › Immunoglobulin-like › Herpesvirus glycoprotein H, C-terminal domain | 0.51 | 36.0 | 3.07e-01 | 76.4% | 91.7% |
| 4durB01 | 3.50.4.10 | Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor | 0.51 | 42.0 | 4.09e-01 | 91.7% | 81.5% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3782443 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.71 | 48.0 | 3.66e-01 | 70.8% | 38.8% |
| 3785874 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.64 | 45.0 | 4.05e-01 | 73.6% | 70.0% |
| 4636769 | 304.24.1.4 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › RF3_C | 0.60 | 45.0 | 3.67e-01 | 80.6% | 74.8% |
| 3712235 | 6171.1.1.0 ↗ | alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases | 0.57 | 49.0 | 3.83e-01 | 100.0% | 59.4% |
| 3888998 | 109.4.1.872 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS1_INTS2-bd | 0.57 | 49.0 | 2.69e-01 | 98.6% | 7.5% |
| 3630326 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.55 | 45.0 | 4.01e-01 | 91.7% | 66.7% |
| 4126506 | 375.1.1.128 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Zn_ribbon_SprT | 0.55 | 33.0 | 3.89e-01 | 79.2% | 86.0% |
| 3928896 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.54 | 44.0 | 4.16e-01 | 91.7% | 84.4% |
| 3505196 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.54 | 44.0 | 4.21e-01 | 91.7% | 82.4% |
| 3240836 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.54 | 44.0 | 4.31e-01 | 91.7% | 86.3% |
| 3305572 | 101.1.2.245 ↗ | alpha arrays › HTH › HTH › winged helix domain › PORR | 0.53 | 40.0 | 2.66e-01 | 83.3% | 73.4% |
| 3619647 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.53 | 43.0 | 3.91e-01 | 91.7% | 68.0% |
| 4000318 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.52 | 37.0 | 3.98e-01 | 90.3% | 90.0% |
| 3246158 | 390.1.1.1 ↗ | few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 | 0.51 | 41.0 | 3.97e-01 | 91.7% | 84.7% |
D2
medium
residues 92-196
Domain cluster:
rep: helicase__YP_006607831__Apocheima_cinerarium_nucleopolyhedrovirus__307461__D33-112
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 39.7 | 1.80e-10 | 98.1% | 7.6% |
D3
medium
residues 197-314
D4
medium
residues 315-463
Domain cluster:
rep: helicase_1__YP_009011148__Mamestra_brassicae_multiple_nucleopolyhedrovirus__78219__D300-447
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 47.0 | 1.10e-12 | 94.6% | 7.1% |
D5
medium
residues 561-611_629-661_782-882
Domain cluster:
rep: DNAhel-1__YP_009121868__Spodoptera_frugiperda_granulovirus__307454__D548-603_748-830
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 91.7 | 3.60e-26 | 78.9% | 7.6% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 23.0 | 3.14e-01 | 90.8% | 72.2% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.55 | 23.0 | 3.56e-01 | 86.5% | 95.9% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 32.0 | 3.19e-01 | 94.1% | 57.9% |
| 2iqcA00 | 1.25.40.490 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 24.0 | 2.51e-01 | 85.4% | 42.2% |
| 3dtoA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.51 | 21.0 | 2.91e-01 | 77.3% | 75.0% |
| 2qgnA02 | 1.10.287.890 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Crystal structure of tRNA isopentenylpyrophosphate transferase (bh2366) domain | 0.51 | 19.0 | 2.78e-01 | 93.0% | 74.4% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3503176 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.52 | 25.0 | 2.84e-01 | 85.4% | 57.3% |
| 3483536 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.52 | 29.0 | 3.40e-01 | 87.6% | 79.2% |
| 3814336 | 603.2.1.13 ↗ | alpha bundles › STAT-like › STAT › STAT › NET2A_C | 0.50 | 28.0 | 3.02e-01 | 93.5% | 62.6% |
D6
medium
residues 883-1006
Domain cluster:
rep: DNA_helicase__YP_009666743__Mythimna_unipuncta_nucleopolyhedrovirus__447897__D942-1031
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04735.17 best | Baculo_helicase | 84.6 | 4.90e-24 | 100.0% | 9.6% |
D7
medium
residues 1095-1177
Domain cluster:
representative
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1eg3A03 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.67 | 54.0 | 5.28e-01 | 89.2% | 92.3% |
| 1dp7P00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.64 | 53.0 | 5.56e-01 | 90.4% | 100.0% |
| 5jgjA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.59 | 49.0 | 3.62e-01 | 95.2% | 47.2% |
| 2f33A03 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.56 | 45.0 | 4.49e-01 | 90.4% | 86.2% |
| 8igrI01 | 2.40.270.10 | Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 | 0.56 | 39.0 | 3.16e-01 | 74.7% | 95.5% |
| 3ccfA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.55 | 46.0 | 3.42e-01 | 95.2% | 43.3% |
| 4v19K02 | 1.10.10.250 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ribosomal protein L11/L12, C-terminal domain | 0.55 | 40.0 | 4.13e-01 | 77.1% | 100.0% |
| 1eg3A04 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.54 | 41.0 | 4.15e-01 | 83.1% | 86.6% |
| 2vxzA02 | 1.10.10.1490 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.53 | 43.0 | 4.32e-01 | 92.8% | 96.6% |
| 4hfvA01 | 1.20.1440.330 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.53 | 37.0 | 3.41e-01 | 74.7% | 90.6% |
| 2mh9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 42.0 | 3.69e-01 | 89.2% | 79.5% |
| 3e4cB00 | 3.40.50.1460 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.52 | 41.0 | 2.94e-01 | 88.0% | 27.1% |
| 4i8oA03 | 1.10.8.1130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain | 0.52 | 30.0 | 3.33e-01 | 95.2% | 71.6% |
| 1ywqA00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.51 | 37.0 | 2.90e-01 | 79.5% | 55.8% |
| 1kpgD00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.51 | 40.0 | 2.89e-01 | 90.4% | 94.0% |
| 5hmpB02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 37.0 | 4.09e-01 | 79.5% | 98.4% |
| 3w9iD03 | 3.30.70.1320 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like | 0.51 | 42.0 | 3.97e-01 | 92.8% | 88.3% |
| 1t6cA02 | 3.30.420.150 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 | 0.50 | 40.0 | 3.20e-01 | 89.2% | 44.2% |
| 5i0hA02 | 1.20.5.4820 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.50 | 37.0 | 3.91e-01 | 80.7% | 97.2% |
ECOD (28)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5022021 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.69 | 62.0 | 5.56e-01 | 98.8% | 77.4% |
| 5081315 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.68 | 57.0 | 5.95e-01 | 89.2% | 100.0% |
| 3177239 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.67 | 59.0 | 4.97e-01 | 96.4% | 91.1% |
| 4560206 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.67 | 55.0 | 5.44e-01 | 91.6% | 85.6% |
| 3883278 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.66 | 59.0 | 5.63e-01 | 97.6% | 90.5% |
| 3498779 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.66 | 56.0 | 5.61e-01 | 94.0% | 98.8% |
| 3698543 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.66 | 55.0 | 5.14e-01 | 92.8% | 85.7% |
| 3856461 | 108.1.1.18 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_2 | 0.65 | 53.0 | 4.75e-01 | 90.4% | 70.0% |
| 4994221 | 4020.1.1.3 ↗ | a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › TFX_C | 0.65 | 43.0 | 4.62e-01 | 81.9% | 81.4% |
| 3713916 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.65 | 52.0 | 4.95e-01 | 88.0% | 85.0% |
| 3898745 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.64 | 57.0 | 5.47e-01 | 98.8% | 93.7% |
| 3537242 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.64 | 56.0 | 5.32e-01 | 97.6% | 84.0% |
| 3393116 | 101.1.2.74 ↗ | alpha arrays › HTH › HTH › winged helix domain › Cnd2 | 0.63 | 52.0 | 4.75e-01 | 89.2% | 87.3% |
| 4159466 | 4020.1.1.0 ↗ | a+b two layers › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes › a+b domain in D-aminoacid aminotransferase-like PLP-dependent enzymes | 0.63 | 47.0 | 4.06e-01 | 94.0% | 50.4% |
| 4200761 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.61 | 53.0 | 3.64e-01 | 95.2% | 39.9% |
| 1736242 | 2003.1.5.8 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Ubie_methyltran | 0.60 | 50.0 | 3.52e-01 | 94.0% | 39.4% |
| 3544517 | 108.1.1.97 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_7 | 0.57 | 42.0 | 4.15e-01 | 78.3% | 77.8% |
| 4804034 | 304.48.1.12 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol | 0.57 | 43.0 | 3.81e-01 | 81.9% | 72.6% |
| 3941182 | 101.1.1.52 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › BrkDBD | 0.54 | 30.0 | 3.35e-01 | 74.7% | 67.7% |
| 4933514 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 47.0 | 4.03e-01 | 100.0% | 95.0% |
| 3938196 | 197.1.1.0 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like | 0.54 | 45.0 | 4.04e-01 | 92.8% | 65.8% |
| 3211387 | 327.19.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › DNA mismatch repair protein MutL regulatory subdomain › DNA mismatch repair protein MutL regulatory subdomain › Mlh1_C | 0.53 | 38.0 | 3.57e-01 | 75.9% | 84.8% |
| 3415227 | 2006.1.6.19 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › IML1 | 0.53 | 46.0 | 3.27e-01 | 98.8% | 90.5% |
| 3444977 | 109.4.1.233 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › VPS53_C | 0.52 | 42.0 | 2.94e-01 | 91.6% | 32.4% |
| 3859640 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 39.0 | 3.09e-01 | 81.9% | 54.2% |
| 5075097 | 2003.1.5.82 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 | 0.52 | 42.0 | 3.03e-01 | 91.6% | 41.1% |
| 3963187 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.51 | 41.0 | 2.92e-01 | 90.4% | 94.6% |
| 3949887 | 2003.1.5.152 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 | 0.50 | 40.0 | 2.86e-01 | 90.4% | 90.7% |