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helicase

Euk-Vir

African_swine_fever_virus

helicase__YP_009702294__African_swine_fever_virus__10497

Identity

Accession:
YP_009702294 ↗
Protein ID:
helicase
Kingdom:
euk

Quality

64.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 267-364
PDB
D2 high residues 378-550
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 68.0 7.10e-19 94.8% 19.4%
D3 high residues 559-695_762-778
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02399.22 best Herpes_ori_bp 31.7 6.70e-08 89.6% 13.8%
D4 high residues 799-870
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3g0oA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.60 41.0 3.51e-01 70.8% 84.3%
4dllB02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 41.0 3.41e-01 70.8% 84.6%
4ga6A02 1.20.970.50 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › 0.58 44.0 3.50e-01 81.9% 61.8%
2uyyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.57 40.0 3.39e-01 73.6% 84.6%
3pvlA03 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.56 39.0 3.29e-01 72.2% 66.1%
7byjA01 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.55 40.0 3.39e-01 77.8% 45.0%
1vpdA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.55 40.0 3.34e-01 76.4% 80.9%
1k20A01 3.90.1640.10 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › inorganic pyrophosphatase (n-terminal core) 0.55 41.0 3.06e-01 80.6% 71.6%
4kv7A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.53 40.0 2.95e-01 83.3% 89.6%
3msxB00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.51 45.0 3.37e-01 100.0% 79.7%
3i45A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 43.0 3.25e-01 98.6% 94.9%
1ym3A00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.51 42.0 3.23e-01 98.6% 76.7%
3td9A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 42.0 3.09e-01 93.1% 95.0%
2c83A01 3.40.50.11120 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domain 0.50 41.0 3.05e-01 94.4% 40.9%
3byiD00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.50 43.0 3.19e-01 100.0% 74.2%
3h49B00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.50 43.0 2.93e-01 100.0% 88.0%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.50 35.0 3.31e-01 73.6% 73.9%
ECOD (20)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3708570 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 51.0 3.77e-01 88.9% 74.4%
3964663 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.63 44.0 3.69e-01 73.6% 84.7%
3452003 109.4.1.1273 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3 0.62 45.0 3.23e-01 76.4% 40.5%
3281183 109.4.1.2061 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4192 0.60 51.0 3.92e-01 100.0% 77.8%
3560132 109.4.1.14 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MyTH4 0.58 50.0 3.74e-01 100.0% 63.6%
3435775 109.4.1.189 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 0.58 43.0 3.19e-01 79.2% 33.3%
3681230 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.58 42.0 3.47e-01 76.4% 83.7%
4589812 3922.1.1.294 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF2418 0.58 44.0 3.89e-01 83.3% 86.4%
3427143 109.4.1.420 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR 0.57 45.0 3.28e-01 83.3% 53.5%
1900653 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.56 40.0 3.32e-01 75.0% 78.5%
4918942 129.1.1.16 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_binding_11 0.56 38.0 3.36e-01 70.8% 91.9%
4108142 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.55 40.0 2.66e-01 79.2% 71.9%
5074457 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.54 37.0 3.32e-01 70.8% 90.5%
4983449 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.54 39.0 3.37e-01 83.3% 47.8%
5069344 2485.4.1.1 a+b three layers › Thioredoxin-like › Fumarate hydratase N-terminal domain › Fumarate hydratase N-terminal domain › Fumerase 0.54 37.0 2.84e-01 72.2% 88.2%
3957083 129.1.1.0 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.52 37.0 3.18e-01 75.0% 88.8%
3266910 189.1.1.2 alpha bundles › GTPase activation domain, GAP › GTPase activation domain, GAP › GTPase activation domain, GAP › RhoGAP 0.51 45.0 3.39e-01 100.0% 73.2%
3327013 109.4.1.775 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 40.0 3.14e-01 87.5% 67.3%
3808366 109.4.1.1382 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_3, TPR_24 0.51 41.0 3.00e-01 91.7% 74.2%
3889071 129.1.1.0 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.50 40.0 3.51e-01 88.9% 98.3%
D5 medium residues 12-70_198-208
PDB
D6 medium residues 71-85_103-197_209-232
PDB
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tupA02 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.68 46.0 5.25e-01 79.1% 94.8%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.67 47.0 5.33e-01 73.9% 96.0%
1f5aA01 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.67 49.0 5.44e-01 82.1% 95.3%
4mt1A02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.67 49.0 5.51e-01 97.0% 100.0%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.67 49.0 5.48e-01 97.0% 99.0%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.66 47.0 5.12e-01 82.1% 87.5%
6ofsA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.64 50.0 4.47e-01 82.1% 95.7%
2rkvA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.64 49.0 4.24e-01 82.1% 91.6%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.63 46.0 5.07e-01 80.6% 94.4%
1m55A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.63 57.0 5.03e-01 98.5% 94.8%
2od6C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 45.0 4.94e-01 82.1% 93.5%
1qpoA01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.63 42.0 4.45e-01 80.6% 76.5%
4i6yA02 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.62 47.0 5.03e-01 81.3% 95.5%
5xoyB02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 47.0 5.17e-01 82.1% 99.1%
2g47A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 48.0 4.02e-01 82.1% 76.5%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.62 48.0 5.12e-01 82.1% 94.9%
3d3yA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 48.0 4.29e-01 82.1% 87.9%
3b49A00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.62 55.0 4.82e-01 98.5% 85.3%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 42.0 4.73e-01 82.1% 93.1%
1q2lA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 48.0 4.03e-01 82.8% 79.7%
4nnzA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.61 48.0 4.19e-01 82.1% 88.9%
4xeaA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.61 47.0 4.22e-01 82.1% 91.7%
1lp9E02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 31.0 3.78e-01 70.9% 77.5%
3d2uA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.60 37.0 4.34e-01 80.6% 88.0%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 47.0 4.00e-01 82.1% 89.4%
4fprB00 3.30.70.2910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 46.0 4.76e-01 81.3% 86.7%
3tqvA01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.60 42.0 4.24e-01 82.1% 72.2%
2f7vA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.90e-01 81.3% 97.2%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 46.0 3.94e-01 82.1% 94.5%
1l2mA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.59 46.0 4.81e-01 98.5% 92.4%
5h9fJ00 3.30.70.2660 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 52.0 4.49e-01 100.0% 98.2%
3amiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.58 45.0 4.00e-01 82.1% 87.4%
1j6wA00 3.30.1360.80 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) 0.58 45.0 4.29e-01 83.6% 86.3%
3gnnA01 3.90.1170.20 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Quinolinate phosphoribosyl transferase, N-terminal domain 0.58 41.0 4.15e-01 82.1% 72.5%
3o4oB03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 39.0 4.21e-01 82.1% 83.5%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.57 42.0 3.61e-01 76.1% 91.0%
3ramA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 44.0 4.67e-01 82.1% 95.8%
2n99A00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.56 30.0 3.83e-01 91.0% 89.5%
3r8jA00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.56 50.0 4.59e-01 98.5% 81.1%
1bwvA01 3.30.70.150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RuBisCO large subunit, N-terminal domain 0.56 43.0 4.40e-01 80.6% 83.6%
4petA01 3.40.190.170 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Bacterial extracellular solute-binding protein, family 7 0.56 39.0 3.35e-01 70.9% 81.4%
2d1cA02 3.30.70.1570 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 43.0 4.64e-01 99.3% 99.1%
2govA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.54 48.0 4.46e-01 98.5% 85.0%
6h8oA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.54 37.0 4.23e-01 98.5% 100.0%
6n2nA01 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.53 37.0 3.38e-01 70.9% 92.7%
3mcsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 46.0 3.96e-01 98.5% 96.3%
2ipiA02 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.51 45.0 3.77e-01 100.0% 90.7%
1pbuA00 3.30.70.1010 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Translation elongation factor EF1B, gamma chain, conserved domain 0.51 41.0 3.95e-01 97.0% 74.1%
1ywhC03 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.51 30.0 3.56e-01 91.0% 87.5%
3popA02 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.50 44.0 3.67e-01 100.0% 90.5%
1d5yB03 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.50 46.0 4.27e-01 99.3% 87.5%
ECOD (79)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3802060 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.79 75.0 5.91e-01 100.0% 60.8%
3677440 862.1.1.11 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R 0.79 75.0 5.96e-01 100.0% 63.7%
3596656 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.73 68.0 5.31e-01 100.0% 63.6%
3719042 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.73 68.0 5.61e-01 100.0% 60.4%
3715696 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.71 67.0 5.08e-01 100.0% 63.9%
4025112 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.67 48.0 5.41e-01 80.6% 99.0%
3735153 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 49.0 5.21e-01 82.1% 89.6%
3484070 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.66 47.0 5.27e-01 80.6% 99.0%
1491756 304.55.1.9 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PV_NSP1 0.64 58.0 4.71e-01 99.3% 91.1%
3609636 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.64 49.0 3.84e-01 82.1% 84.8%
4319983 304.55.1.25 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_1 0.63 58.0 4.79e-01 100.0% 78.3%
4630093 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.63 45.0 4.72e-01 77.6% 81.7%
3588046 304.55.1.14 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Y2_Tnp 0.63 56.0 4.47e-01 96.3% 81.5%
3280414 304.133.1.1 a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.63 45.0 4.96e-01 82.1% 94.3%
None 0.62 55.0 4.49e-01 97.0% 86.8%
4447424 304.55.1.26 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › RepSA 0.62 56.0 4.44e-01 100.0% 85.8%
3986356 304.55.1.14 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Y2_Tnp 0.62 55.0 4.31e-01 97.0% 77.5%
5511 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.62 48.0 3.98e-01 82.8% 76.7%
1183437 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.61 48.0 4.14e-01 82.1% 85.9%
3301512 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.61 48.0 3.97e-01 82.8% 79.6%
3164823 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.61 47.0 3.98e-01 82.1% 83.0%
3735269 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.61 47.0 3.82e-01 82.1% 48.5%
3494040 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.61 47.0 4.58e-01 80.6% 77.2%
3750557 304.47.1.0 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.61 49.0 5.20e-01 88.1% 99.1%
3700802 304.20.1.0 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.61 55.0 5.42e-01 99.3% 97.2%
4007464 304.55.1.19 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Inovirus_Gp2 0.61 54.0 4.79e-01 97.0% 91.1%
4236888 304.10.1.0 a+b two layers › Alpha-beta plaits › RuBisCO, large subunit, small (N-terminal) domain › RuBisCO, large subunit, small (N-terminal) domain 0.61 45.0 4.85e-01 81.3% 93.6%
3445307 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.61 47.0 3.93e-01 82.8% 79.6%
3652924 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.61 47.0 3.91e-01 82.1% 84.7%
3993060 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.60 46.0 4.88e-01 81.3% 93.3%
2388574 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.60 46.0 3.91e-01 81.3% 84.8%
3647805 309.1.1.17 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, Peptidase_M16_M, PqqF-like_C_4 0.60 48.0 2.90e-01 85.8% 22.7%
1182828 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.60 47.0 4.01e-01 82.1% 88.0%
4959045 304.8.1.81 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P 0.60 50.0 4.83e-01 96.3% 79.3%
5010477 331.2.1.0 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain 0.60 43.0 4.85e-01 80.6% 100.0%
5066211 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.60 46.0 4.20e-01 82.1% 90.7%
2834623 304.55.1.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N 0.60 54.0 5.00e-01 100.0% 99.4%
4965450 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.59 44.0 4.84e-01 82.1% 95.5%
3609026 304.20.1.0 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.59 54.0 5.30e-01 99.3% 96.6%
3384464 304.127.1.0 a+b two layers › Alpha-beta plaits › Notch heterodimerization domain › Notch heterodimerization domain 0.59 46.0 4.67e-01 82.1% 100.0%
3343879 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.59 45.0 4.57e-01 79.9% 96.9%
5035799 304.57.1.1 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like › RNase_P_Rpp14 0.59 46.0 4.76e-01 87.3% 88.7%
3280291 304.133.1.1 a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.59 46.0 4.69e-01 82.1% 85.4%
3175129 6169.1.1.45 extended segments › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › Transmembrane segment of lysosome-associated membrane glycoprotein 2 › PF27810 0.59 44.0 4.73e-01 79.9% 95.7%
142220 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.58 45.0 3.99e-01 82.1% 87.0%
3791663 304.4.1.52 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF7153 0.58 52.0 4.33e-01 97.0% 97.8%
3227272 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.58 43.0 4.09e-01 76.9% 81.9%
4133039 304.8.1.81 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P 0.58 52.0 4.82e-01 97.0% 87.3%
3196491 304.49.1.5 a+b two layers › Alpha-beta plaits › TRADD, N-terminal domain/Dystroglycan, domain 2 › TRADD, N-terminal domain/Dystroglycan, domain 2 › PF27810 0.58 45.0 4.85e-01 86.6% 98.3%
3697218 327.11.2.35 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29984 0.58 37.0 4.33e-01 74.6% 100.0%
3214818 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.57 45.0 3.27e-01 82.1% 98.9%
3773609 304.15.1.6 a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain › SGT1 0.57 46.0 4.13e-01 85.8% 83.2%
3353115 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.57 40.0 3.28e-01 72.4% 68.1%
4962041 304.55.1.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains 0.57 49.0 4.36e-01 94.8% 88.5%
3545806 509.1.1.15 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › SGT1 0.57 46.0 4.09e-01 85.8% 83.2%
4015784 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.57 44.0 3.56e-01 82.1% 43.8%
4521182 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.56 43.0 3.63e-01 82.1% 48.8%
4304749 304.8.1.81 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P 0.55 50.0 4.03e-01 100.0% 72.7%
5004083 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.55 49.0 4.13e-01 97.8% 90.7%
4030594 304.46.1.1 a+b two layers › Alpha-beta plaits › eEF1-gamma domain › eEF1-gamma domain › EF1G 0.54 44.0 4.23e-01 97.0% 74.4%
7321 886.1.1.2 a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › GyrI-like 0.54 49.0 4.56e-01 98.5% 86.4%
4018928 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.54 48.0 3.90e-01 100.0% 81.1%
3277124 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.53 48.0 3.87e-01 100.0% 83.4%
3185512 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.53 47.0 3.91e-01 100.0% 83.0%
8275 382.1.1.1 few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › UPAR_LY6 0.53 30.0 3.67e-01 90.3% 88.1%
4035986 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.53 47.0 3.92e-01 99.3% 83.7%
4222843 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.52 46.0 3.74e-01 100.0% 81.7%
5000685 304.102.1.3 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_1 0.52 42.0 3.43e-01 87.3% 66.3%
4929353 2003.1.5.13 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.52 39.0 2.90e-01 78.4% 95.4%
4015323 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.52 45.0 3.75e-01 98.5% 83.6%
4965842 2003.1.5.13 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.51 38.0 3.07e-01 76.9% 88.5%
3718659 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.51 42.0 2.77e-01 89.6% 55.3%
4342843 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.51 45.0 3.77e-01 99.3% 83.3%
3275597 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.51 45.0 3.73e-01 100.0% 82.4%
3834037 304.9.1.114 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1, RRM_2 0.51 44.0 3.18e-01 97.0% 33.6%
3863526 11.1.1.108 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C2-set_2 0.51 36.0 3.82e-01 80.6% 83.5%
4018691 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.51 45.0 3.68e-01 100.0% 83.1%
3638657 304.6.1.3 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.51 45.0 3.68e-01 100.0% 83.8%
3634940 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.50 45.0 3.65e-01 100.0% 83.8%
D7 medium residues 696-761
PDB
D8 medium residues 912-937_960-1008
PDB