helicase_primase_complex

Euk-Vir

Human_betaherpesvirus_6B

helicase_primase_complex__NP_050224__Human_betaherpesvirus_6B__32604

Identity

85.1 mean pLDDT

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Human_betaherpesvirus_6B

TaxID: 32604

View cluster (58 members)

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high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 724-855

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	79.3	2.20e-22	57.6%	97.3%

D2 medium residues 1-141

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162

D3 medium residues 142-241

PDB

Domain cluster: representative

CATH (7)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5cbgA00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.64	38.0	3.83e-01	89.0%	57.8%
8ctsB01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.62	39.0	4.21e-01	93.0%	73.6%
7e84A03	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.62	39.0	3.65e-01	93.0%	51.2%
1c9bA01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.60	36.0	3.74e-01	75.0%	61.9%
3ljcA02	1.20.58.1480	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.57	45.0	4.13e-01	83.0%	73.0%
1sqgA01	1.10.940.10	Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like	0.51	41.0	3.70e-01	87.0%	89.4%
1rxqD00	1.20.120.450	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain	0.51	39.0	3.27e-01	81.0%	94.1%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4992346	102.2.1.0 ↗	alpha arrays › HhH/H2TH › H2TH › H2TH	0.60	39.0	4.22e-01	75.0%	81.2%
3642946	142.1.1.0 ↗	alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors	0.58	41.0	4.45e-01	73.0%	95.0%
3797401	206.1.1.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase	0.58	50.0	3.14e-01	96.0%	41.4%
147042	3254.1.1.1 ↗	alpha arrays › helical domain in flagellar biosynthesis protein flhA › helical domain in flagellar biosynthesis protein flhA › helical domain in flagellar biosynthesis protein flhA › FHIPEP	0.57	37.0	3.83e-01	81.0%	70.3%
3996112	601.7.1.21 ↗	alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › NICE-3	0.56	41.0	3.96e-01	79.0%	80.8%
3722676	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.55	39.0	4.21e-01	98.0%	88.1%
3213337	102.1.1.16 ↗	alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_2	0.53	30.0	3.25e-01	72.0%	62.4%
3437255	611.7.1.1 ↗	alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MLKL_N	0.52	47.0	4.41e-01	98.0%	88.3%

D4 medium residues 242-329_705-718

PDB

Domain cluster: rep: protein_UL70__YP_004933833__Cynomolgus_macaque_cytomegalovirus_strain_Ottawa__944969__D246-322

D5 medium residues 330-485_630-645

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_182338__Gallid_alphaherpesvirus_1__10386__D431-468_522-592_634-660

D6 medium residues 486-629_646-704

PDB

Domain cluster: rep: primase__YP_009345453__Noumeavirus__1955558__D12-194