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helper_component_protease,_HC-Pro
Euk-VirNarcissus_degeneration_virus
helper_component_protease,_HC-Pro__YP_001019189__Narcissus_degeneration_virus__394036
Identity
- Accession:
- YP_001019189 ↗
- Protein ID:
- helper_component_protease,_HC-Pro
- Kingdom:
- euk
Quality
83.2
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Narcissus_degeneration_virus
TaxID: 394036
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 28-104
Domain cluster:
rep: HC-Pro__YP_331415__Shallot_yellow_stripe_virus__62059__D30-100
D2
high
residues 111-171
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.81 | 56.0 | 5.06e-01 | 72.1% | 71.6% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 54.0 | 5.01e-01 | 72.1% | 84.4% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 53.0 | 5.07e-01 | 72.1% | 63.4% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.77 | 54.0 | 5.38e-01 | 73.8% | 85.9% |
| 1wtyA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.76 | 51.0 | 4.08e-01 | 72.1% | 36.2% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 51.0 | 4.82e-01 | 72.1% | 61.3% |
| 7zm7601 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.72 | 55.0 | 4.02e-01 | 83.6% | 37.1% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.70 | 48.0 | 4.75e-01 | 70.5% | 84.1% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.69 | 55.0 | 4.56e-01 | 85.2% | 93.4% |
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 60.0 | 4.27e-01 | 100.0% | 69.0% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.69 | 48.0 | 4.41e-01 | 72.1% | 84.6% |
| 6dcjA02 | 1.25.40.650 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 46.0 | 3.85e-01 | 72.1% | 94.2% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 46.0 | 4.06e-01 | 72.1% | 54.4% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.66 | 46.0 | 4.30e-01 | 72.1% | 57.1% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 53.0 | 4.47e-01 | 95.1% | 53.9% |
| 2lhrA00 | 1.20.58.1270 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 45.0 | 4.23e-01 | 73.8% | 59.0% |
| 1un8A02 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.64 | 47.0 | 3.37e-01 | 78.7% | 52.6% |
| 8e9gJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.64 | 51.0 | 3.80e-01 | 90.2% | 38.9% |
| 2afaA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.64 | 56.0 | 3.35e-01 | 96.7% | 38.5% |
| 6ljaA01 | 1.50.10.100 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase | 0.64 | 55.0 | 3.44e-01 | 100.0% | 43.9% |
| 1vfpB02 | 1.20.1110.10 | Mainly Alpha › Up-down Bundle › Calcium-transporting ATPase, transmembrane domain › Calcium-transporting ATPase, transmembrane domain | 0.63 | 50.0 | 3.05e-01 | 88.5% | 88.5% |
| 3gt5A00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.62 | 55.0 | 3.34e-01 | 100.0% | 52.4% |
| 1b68A00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.59 | 52.0 | 4.01e-01 | 98.4% | 76.8% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 43.0 | 3.34e-01 | 80.3% | 51.0% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 43.0 | 2.92e-01 | 85.2% | 70.8% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.58 | 52.0 | 3.87e-01 | 100.0% | 85.2% |
| 2cdqA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.57 | 48.0 | 4.19e-01 | 96.7% | 78.4% |
| 6h5hA00 | 1.10.150.110 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like | 0.57 | 44.0 | 4.28e-01 | 86.9% | 78.9% |
| 4citA00 | 1.10.606.20 | Mainly Alpha › Orthogonal Bundle › Vanadium-containing Chloroperoxidase; domain 2 › | 0.56 | 43.0 | 2.72e-01 | 90.2% | 50.5% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.56 | 46.0 | 3.57e-01 | 91.8% | 62.4% |
| 2ap3A00 | 1.20.120.570 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YkyA-like | 0.56 | 45.0 | 3.38e-01 | 100.0% | 57.3% |
| 2igsA00 | 1.10.3690.10 | Mainly Alpha › Orthogonal Bundle › PA2222-like fold › PA2222-like domain | 0.55 | 46.0 | 3.25e-01 | 98.4% | 32.7% |
| 6fakA02 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.55 | 47.0 | 4.31e-01 | 98.4% | 93.8% |
| 4j8dD00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 43.0 | 3.28e-01 | 98.4% | 37.0% |
| 2kxpA01 | 3.30.1140.60 | Alpha Beta › 2-Layer Sandwich › Ribosomal protein S3 C-terminal domain › F-actin capping protein, alpha subunit | 0.51 | 34.0 | 2.93e-01 | 70.5% | 49.5% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 43.0 | 3.44e-01 | 100.0% | 56.4% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5083776 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.82 | 57.0 | 4.85e-01 | 72.1% | 53.7% |
| 3471420 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.82 | 70.0 | 5.90e-01 | 95.1% | 80.0% |
| 3452645 | 101.35.1.31 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › Gliadin | 0.71 | 43.0 | 3.68e-01 | 100.0% | 40.0% |
| 3282049 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.67 | 56.0 | 5.72e-01 | 93.4% | 100.0% |
| 3741609 | 109.58.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA repair protein Rev1 C-terminal domain › DNA repair protein Rev1 C-terminal domain › REV1_C | 0.66 | 53.0 | 4.53e-01 | 85.2% | 88.4% |
| 1503553 | 3796.1.1.1 ↗ | alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Isd_H_B_linker | 0.65 | 45.0 | 4.23e-01 | 73.8% | 59.0% |
| 3940293 | 188.1.1.0 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain | 0.63 | 51.0 | 3.61e-01 | 96.7% | 41.4% |
| 3173383 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.60 | 47.0 | 3.75e-01 | 83.6% | 74.6% |
| 5048365 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 53.0 | 3.53e-01 | 98.4% | 57.9% |
| 3422458 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.60 | 47.0 | 4.52e-01 | 86.9% | 77.1% |
| 3711255 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 45.0 | 3.33e-01 | 86.9% | 56.2% |
| 3594688 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 48.0 | 3.14e-01 | 95.1% | 83.0% |
| 3595433 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 48.0 | 3.34e-01 | 96.7% | 42.6% |
| 5051025 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.51 | 35.0 | 3.06e-01 | 75.4% | 46.7% |
D3
medium
residues 190-208_225-340_420-431
Domain cluster:
rep: HcPro__YP_010088120__Dendrobium_chlorotic_mosaic_virus__2562807__D178-290_309-337
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 80.8 | 1.40e-22 | 98.0% | 28.2% |
D4
medium
residues 209-224_341-419_432-458
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 107.2 | 1.40e-30 | 95.1% | 27.3% |