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hemagglutinin-neuraminidase

Euk-Vir

Simian_Agent_10

hemagglutinin-neuraminidase__YP_009505440__Simian_Agent_10__929831

Identity

Accession:
YP_009505440 ↗
Protein ID:
hemagglutinin-neuraminidase
Kingdom:
euk

Quality

83.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 40-127
PDB
D2 medium residues 146-212_426-572
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 155.0 3.60e-45 68.2% 26.4%
PF00423.27 HN 41.5 9.20e-11 31.8% 12.2%
D3 medium residues 213-226_241-307
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 50.5 1.70e-13 100.0% 12.9%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1v3eA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.97 94.0 5.64e-01 100.0% 22.0%
1e8uA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.92 87.0 5.27e-01 100.0% 21.3%
1z4vA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.88 83.0 5.04e-01 100.0% 21.2%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.81 47.0 3.85e-01 92.6% 34.3%
1ms9A01 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.80 73.0 4.66e-01 100.0% 28.7%
4uf7B00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.79 73.0 4.52e-01 100.0% 23.3%
1wznA02 2.20.25.110 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › S-adenosyl-L-methionine-dependent methyltransferases 0.75 47.0 5.58e-01 95.1% 92.9%
2h36X00 3.30.160.300 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 49.0 4.49e-01 80.2% 57.4%
3vsfC01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.66 60.0 3.92e-01 100.0% 40.9%
6eufA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.66 59.0 3.97e-01 100.0% 43.2%
3cnxA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 52.0 4.33e-01 86.4% 94.9%
3f7sA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.64 52.0 4.26e-01 86.4% 85.9%
3os7A00 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.63 57.0 3.77e-01 100.0% 93.5%
7bwcA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.63 56.0 3.76e-01 100.0% 26.6%
6nobA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.63 52.0 3.40e-01 93.8% 44.8%
4kcaA02 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.62 55.0 3.55e-01 100.0% 55.5%
3pieB05 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.62 35.0 3.87e-01 77.8% 70.3%
3akhA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.61 54.0 3.64e-01 98.8% 36.8%
5jozA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.61 54.0 3.63e-01 97.5% 36.1%
2pndA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.61 41.0 3.64e-01 70.4% 87.4%
3qeeB00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.60 54.0 3.66e-01 100.0% 32.1%
1ospO02 3.90.930.1 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › 0.59 46.0 3.83e-01 93.8% 47.3%
4mlgG00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.59 52.0 3.52e-01 100.0% 30.2%
4aq1A02 2.60.40.1080 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 42.0 4.07e-01 75.3% 92.3%
3pijA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.58 51.0 3.35e-01 100.0% 37.4%
4jguA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 41.0 3.95e-01 75.3% 82.1%
3sokB00 3.30.700.10 Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › Glycoprotein, Type 4 Pilin 0.57 47.0 3.96e-01 91.4% 69.0%
3dzmB00 2.40.160.70 Mainly Beta › Beta Barrel › Porin › outer membrane protein from Thermus thermophilus HB27. 0.56 51.0 3.78e-01 100.0% 76.5%
1ejfA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 42.0 3.85e-01 81.5% 84.5%
4eq3A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 39.0 3.61e-01 75.3% 91.7%
4r1kB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 43.0 3.62e-01 95.1% 50.0%
4ei0A01 2.60.40.3550 Mainly Beta › Sandwich › Immunoglobulin-like › Domain of unknown function DUF4466 0.55 39.0 3.30e-01 75.3% 90.8%
1rl1A00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 40.0 3.90e-01 77.8% 92.4%
2qsqB01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 38.0 3.49e-01 72.8% 93.5%
2xg5A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 3.86e-01 79.0% 89.1%
3q48A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 38.0 3.82e-01 76.5% 90.4%
4binA01 2.60.40.3500 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 40.0 3.58e-01 80.2% 72.4%
2xcmC00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 40.0 3.86e-01 80.2% 94.6%
4ofyD01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 38.0 3.52e-01 76.5% 97.1%
2ox5B00 2.60.40.2470 Mainly Beta › Sandwich › Immunoglobulin-like › SoxY domain 0.52 46.0 4.08e-01 93.8% 95.5%
1ix2A00 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 3.46e-01 75.3% 95.1%
2db2A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.51 36.0 3.45e-01 74.1% 73.4%
1amiA04 3.20.19.10 Alpha Beta › Alpha-Beta Barrel › Aconitase; domain 4 › Aconitase, domain 4 0.51 39.0 2.96e-01 86.4% 57.5%
4aq1A03 2.60.40.3440 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 37.0 3.33e-01 77.8% 87.0%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1112626 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.97 94.0 5.61e-01 100.0% 21.7%
152420 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.93 88.0 5.22e-01 100.0% 19.5%
4889672 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.92 87.0 5.28e-01 100.0% 22.1%
1563144 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.91 86.0 5.14e-01 100.0% 19.9%
2541822 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.87 82.0 6.05e-01 100.0% 52.7%
3062082 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.87 82.0 5.00e-01 100.0% 21.9%
3062081 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.82 76.0 4.70e-01 100.0% 22.4%
1519176 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.80 73.0 4.56e-01 100.0% 23.0%
2093820 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.75 69.0 4.27e-01 100.0% 22.1%
2833528 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.75 68.0 4.15e-01 100.0% 21.0%
5037296 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.72 64.0 4.32e-01 98.8% 40.3%
3962355 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.71 49.0 3.60e-01 71.6% 31.0%
4572880 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.70 64.0 3.96e-01 100.0% 36.6%
3737383 708.1.1.10 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › SWI-SNF_Ssr4_N 0.69 53.0 4.21e-01 81.5% 45.0%
3958189 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.69 48.0 4.08e-01 71.6% 49.6%
None 0.69 48.0 3.10e-01 71.6% 18.5%
3957639 2484.1.1.18 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.68 47.0 3.19e-01 71.6% 21.4%
3017638 5.1.3.5 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.68 61.0 3.76e-01 98.8% 25.4%
3393071 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.68 60.0 3.76e-01 100.0% 42.3%
3277859 243.1.1.25 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_3 0.67 54.0 4.56e-01 86.4% 96.2%
3287136 243.1.1.25 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_3 0.67 53.0 4.55e-01 86.4% 96.2%
3483569 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.67 58.0 3.68e-01 100.0% 32.2%
5081947 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.66 60.0 3.95e-01 100.0% 43.6%
3743230 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.66 59.0 3.68e-01 100.0% 28.9%
3559236 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.66 41.0 4.78e-01 75.3% 90.9%
5030007 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.66 39.0 4.10e-01 72.8% 64.0%
3508283 5.1.5.156 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Beta-prop_RSE1_1st 0.66 57.0 3.64e-01 100.0% 41.8%
4228036 5.1.4.17 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CPSF_A,MMS1_N 0.65 57.0 3.31e-01 100.0% 19.8%
3365640 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.65 56.0 3.61e-01 100.0% 41.9%
5010537 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.64 41.0 4.17e-01 75.3% 65.8%
4104247 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.64 55.0 3.51e-01 100.0% 39.8%
5067191 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.64 39.0 3.99e-01 72.8% 62.5%
4584755 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.64 56.0 3.57e-01 100.0% 28.9%
5040713 5.1.4.87 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › LVIVD 0.63 56.0 3.48e-01 100.0% 31.0%
4203120 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.63 55.0 3.50e-01 100.0% 40.9%
4994841 5.1.2.7 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_130 0.63 55.0 3.65e-01 100.0% 53.4%
3422361 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.62 52.0 5.43e-01 93.8% 96.0%
3167001 5.1.4.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MMS1_N 0.62 53.0 3.44e-01 100.0% 37.9%
3523657 5.1.4.18 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › EPTP 0.62 55.0 3.53e-01 100.0% 43.4%
3916215 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.62 53.0 3.42e-01 93.8% 20.8%
3961876 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 42.0 2.80e-01 72.8% 18.3%
3303486 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.58 41.0 3.73e-01 75.3% 76.4%
5042256 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.57 35.0 3.35e-01 72.8% 50.5%
3742788 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.56 42.0 3.83e-01 77.8% 82.9%
3696868 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.56 41.0 3.64e-01 77.8% 74.2%
4523548 4.8.1.35 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › DUF1292 0.55 41.0 4.12e-01 80.2% 82.4%
4951666 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 38.0 3.45e-01 71.6% 82.7%
3933767 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.55 44.0 3.97e-01 88.9% 92.2%
5056676 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.55 36.0 3.43e-01 77.8% 55.0%
3453844 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.54 46.0 3.18e-01 98.8% 45.5%
3443821 331.3.1.3 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.54 39.0 3.49e-01 77.8% 64.2%
5055486 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.54 36.0 3.58e-01 74.1% 65.9%
3413099 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.53 43.0 4.00e-01 87.7% 94.0%
3302402 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.53 41.0 3.81e-01 81.5% 85.0%
3930732 2004.1.1.442 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 0.51 44.0 2.89e-01 93.8% 34.7%
3278540 222.1.1.9 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › MaoC_dehydrat_N 0.51 44.0 3.62e-01 96.3% 93.3%
4432262 319.1.1.3 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.51 41.0 3.60e-01 93.8% 58.3%
3967435 1.1.13.5 beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Phage_GPD 0.51 39.0 3.74e-01 82.7% 97.9%
3966280 1.1.13.0 beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.51 39.0 3.72e-01 82.7% 97.9%
D4 medium residues 308-425
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 136.7 1.30e-39 100.0% 22.1%