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hemagglutinin-neuraminidase

Euk-Vir

Avian_metaavulavirus_2

hemagglutinin-neuraminidase__YP_009513218__Avian_metaavulavirus_2__2560313

Identity

Accession:
YP_009513218 ↗
Protein ID:
hemagglutinin-neuraminidase
Kingdom:
euk

Quality

80.3 mean pLDDT

Taxonomy

Orthornavirae› Negarnaviricota› Monjiviricetes› Mononegavirales› Paramyxoviridae› Metaavulavirus› avian_paramyxovirus_2

TaxID: 2560313

Cluster

View cluster (61 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 130-175_515-577
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 51.1 1.10e-13 55.0% 10.5%
PF00423.27 HN 27.5 1.60e-06 43.1% 9.2%
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1z4vA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.92 86.0 5.49e-01 98.2% 99.5%
1e8uA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.89 83.0 5.33e-01 99.1% 98.9%
1v3eA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.81 76.0 4.93e-01 100.0% 99.3%
2vsmA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.75 64.0 4.15e-01 89.0% 99.8%
4uf7B00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.73 62.0 4.08e-01 89.9% 98.8%
3s4kA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.61 38.0 3.65e-01 85.3% 54.0%
3n91A02 2.40.128.420 Mainly Beta › Beta Barrel › Lipocalin › 0.61 45.0 4.23e-01 78.9% 99.3%
1q4tA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.60 38.0 3.47e-01 85.3% 48.6%
1pn2B01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.59 40.0 3.59e-01 88.1% 50.7%
1b9vA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.56 48.0 3.38e-01 98.2% 96.2%
3b7kB01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.55 36.0 3.35e-01 90.8% 51.4%
3r0qA02 2.70.160.11 Mainly Beta › Distorted Sandwich › Hnrnp arginine n-methyltransferase1 › Hnrnp arginine n-methyltransferase1 0.55 39.0 3.16e-01 74.3% 73.1%
1m6kA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.55 40.0 3.08e-01 77.1% 88.4%
4dkmA00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.54 45.0 3.62e-01 89.9% 51.2%
2wstA00 2.60.90.10 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › Adenovirus pIV-related, attachment domain 0.54 38.0 3.27e-01 73.4% 58.5%
2qkpD00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.54 39.0 3.65e-01 76.1% 82.1%
6xrbA01 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.53 37.0 3.48e-01 72.5% 66.2%
6rtqA00 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.52 43.0 4.02e-01 89.0% 94.7%
2dd7A00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.52 43.0 3.50e-01 90.8% 50.9%
4l8nA03 3.30.160.670 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.52 36.0 3.23e-01 72.5% 87.2%
2o62A02 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.52 45.0 4.15e-01 93.6% 100.0%
1sh8B00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.52 36.0 3.24e-01 83.5% 51.7%
3ia8A00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.52 41.0 3.63e-01 86.2% 95.7%
6oodA01 2.40.480.10 Mainly Beta › Beta Barrel › AOC barrel-like › Allene oxide cyclase-like 0.51 35.0 3.24e-01 70.6% 79.1%
3pquA02 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.51 43.0 3.75e-01 94.5% 96.6%
2v1oB00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.51 37.0 3.36e-01 90.8% 56.1%
2hngA00 3.10.420.10 Alpha Beta › Roll › Bacterial Protein-export protein SecB › SecB-like 0.50 36.0 3.45e-01 77.1% 64.0%
3jtyB01 2.40.160.10 Mainly Beta › Beta Barrel › Porin › Porin 0.50 39.0 2.71e-01 82.6% 99.5%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1563144 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.92 86.0 5.38e-01 98.2% 90.7%
152420 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.90 85.0 5.36e-01 100.0% 90.9%
4889672 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.85 79.0 5.07e-01 97.2% 99.3%
1112626 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.81 76.0 4.90e-01 100.0% 97.9%
3062081 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.79 73.0 4.78e-01 100.0% 99.3%
3062082 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.79 73.0 4.78e-01 100.0% 98.6%
3230100 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.67 35.0 4.76e-01 84.4% 100.0%
3017638 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.64 59.0 3.82e-01 100.0% 91.3%
3696265 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 46.0 3.72e-01 80.7% 97.1%
4000635 331.3.1.6 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like › PRELI 0.59 39.0 3.29e-01 79.8% 41.1%
3953766 222.1.1.0 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.57 42.0 3.54e-01 77.1% 81.1%
3617004 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 43.0 4.21e-01 78.9% 76.5%
3962890 222.1.1.0 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.56 38.0 3.68e-01 76.1% 61.6%
4937367 504.1.1.0 ↗ a+b two layers › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB › Bacterial protein-export protein SecB 0.56 38.0 3.67e-01 77.1% 61.6%
3184931 868.1.1.0 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related 0.55 42.0 3.24e-01 81.7% 83.5%
3323788 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.55 41.0 3.00e-01 92.7% 28.2%
3989572 223.1.1.27 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_10 0.55 40.0 3.58e-01 76.1% 73.8%
4247068 223.3.1.3 ↗ a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.54 40.0 3.08e-01 77.1% 88.8%
3631673 222.1.1.27 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PF27832 0.54 46.0 3.89e-01 91.7% 95.0%
4227522 330.6.1.0 ↗ a+b two layers › dsRBD-like › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain › 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 0.53 38.0 3.87e-01 96.3% 75.2%
3236031 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.53 37.0 3.40e-01 72.5% 84.1%
3720671 222.1.1.27 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PF27832 0.53 45.0 3.78e-01 91.7% 95.6%
3818615 5.1.3.118 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.53 40.0 2.85e-01 91.7% 26.7%
1283375 271.1.1.1 ↗ beta barrels › GFP-like › GFP-like › GFP-like › GFP 0.52 44.0 3.54e-01 92.7% 49.3%
4189433 223.1.1.81 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › Cache_WalK 0.52 42.0 3.47e-01 87.2% 75.0%
3962603 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.52 38.0 3.80e-01 76.1% 85.5%
3698558 331.9.1.0 ↗ a+b two layers › TBP-like › Subdomain of clathrin and coatomer appendage domain › Subdomain of clathrin and coatomer appendage domain 0.52 38.0 3.48e-01 78.0% 74.3%
852 9.1.1.29 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › BFA1_C 0.52 45.0 4.15e-01 93.6% 100.0%
3917130 331.3.1.0 ↗ a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.51 34.0 2.70e-01 76.1% 33.2%
5037261 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.51 37.0 3.35e-01 77.1% 64.5%
3291496 868.1.1.0 ↗ a+b complex topology › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related › mRNA triphosphatase CET1-related 0.51 39.0 3.05e-01 82.6% 85.9%
None — 0.51 40.0 2.79e-01 82.6% 52.8%
3278559 881.1.1.0 ↗ a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.50 38.0 3.26e-01 78.9% 74.1%
3962355 2484.1.1.18 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1 0.50 38.0 3.09e-01 79.8% 56.5%
D2 medium residues 176-255
PDB
Domain cluster: rep: attachment_protein__YP_006347588__Nariva_virus__590647__D242-318
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 116.9 1.30e-33 100.0% 15.0%
D3 medium residues 256-514
PDB
Domain cluster: rep: hemagglutinin-neuraminidase_protein__YP_009508497__Avian_paramyxovirus_14__1928005__D254-485
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 249.6 8.20e-74 100.0% 44.0%