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hemagglutinin-neuraminidase_protein

Euk-Vir

Avian_paramyxovirus_UPO216

hemagglutinin-neuraminidase_protein__YP_009508503__Avian_paramyxovirus_UPO216__2006690

Identity

Accession:
YP_009508503 ↗
Protein ID:
hemagglutinin-neuraminidase_protein
Kingdom:
euk

Quality

78.8 mean pLDDT

Taxonomy

Orthornavirae› Negarnaviricota› Monjiviricetes› Mononegavirales› Paramyxoviridae› Orthoavulavirus› avian_paramyxovirus_16

TaxID: 2006690

Cluster

View cluster (61 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 70-121
PDB
D2 medium residues 141-470_525-567
PDB
Domain cluster: rep: hemagglutinin-neuraminidase_protein__YP_009508497__Avian_paramyxovirus_14__1928005__D254-485
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00423.27 best HN 359.7 3.40e-107 88.5% 58.2%
PF00423.27 HN 40.6 1.70e-10 11.5% 7.3%
D3 medium residues 471-524
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1e8uA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.99 96.0 5.40e-01 100.0% 12.1%
2vsmA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.93 80.0 4.64e-01 100.0% 12.1%
1v3eA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.89 76.0 4.41e-01 100.0% 11.6%
1z4vA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.88 81.0 4.65e-01 100.0% 13.1%
4uf7B00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.81 68.0 3.97e-01 100.0% 12.1%
1inyA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.71 61.0 3.64e-01 100.0% 13.7%
4fvkA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.70 56.0 3.42e-01 100.0% 13.6%
2jkbA02 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.68 61.0 3.64e-01 100.0% 15.9%
1so7A00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.65 56.0 3.42e-01 100.0% 15.2%
3eo5A01 2.20.230.10 Mainly Beta › Single Sheet › Resuscitation-promoting factor rpfb fold › Resuscitation-promoting factor rpfb. 0.64 46.0 3.97e-01 77.8% 79.5%
8gn6A01 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.63 51.0 3.18e-01 100.0% 15.1%
6gbuD00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.62 38.0 3.60e-01 74.1% 50.0%
3s95A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.62 46.0 3.97e-01 81.5% 86.4%
6e20A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.61 49.0 3.75e-01 100.0% 37.1%
2w20B01 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.61 52.0 3.13e-01 100.0% 13.9%
3wucB00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.61 49.0 3.67e-01 100.0% 35.8%
3d4eA02 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.60 48.0 4.30e-01 92.6% 62.8%
7ne4A01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.60 46.0 2.88e-01 100.0% 14.3%
4agrB00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.60 49.0 3.67e-01 100.0% 35.4%
1b9vA00 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.60 49.0 3.01e-01 100.0% 15.1%
2w38A01 2.120.10.10 Mainly Beta › 6 Propeller › Neuraminidase › 0.59 51.0 3.18e-01 100.0% 17.8%
5gm0A01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.58 46.0 3.45e-01 100.0% 33.1%
6htnA01 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.58 45.0 3.47e-01 100.0% 35.8%
3gmvX00 3.10.450.730 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › BLIP domain 0.57 46.0 3.43e-01 94.4% 32.7%
3k1lA01 3.30.457.40 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › 0.57 45.0 3.93e-01 94.4% 85.9%
1gbgA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.57 45.0 3.12e-01 100.0% 23.8%
4gl6A01 3.10.450.570 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Domain of unknown function (DUF5037), N-terminal subdomain 0.56 45.0 4.09e-01 96.3% 74.4%
2hb5A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 38.0 2.87e-01 79.6% 89.3%
4r8oA00 2.40.128.720 Mainly Beta › Beta Barrel › Lipocalin › 0.53 42.0 3.63e-01 98.1% 55.1%
2kvtA00 3.30.730.30 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › YaiA protein 0.52 35.0 3.34e-01 72.2% 60.6%
2avtA02 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.52 37.0 2.66e-01 90.7% 22.1%
2oc3A00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.52 41.0 2.67e-01 92.6% 20.1%
3oyyA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.51 37.0 3.51e-01 77.8% 100.0%
5eoxB03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 36.0 2.86e-01 77.8% 84.4%
6ovbA03 2.100.10.10 Mainly Beta › Aligned Prism › Vitelline Membrane Outer Layer Protein I, subunit A › Pesticidal crystal protein, central domain 0.51 35.0 2.55e-01 74.1% 73.8%
6ro0B02 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.51 36.0 2.96e-01 75.9% 89.1%
2lkoA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 37.0 2.74e-01 77.8% 61.6%
1u6zA02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.51 36.0 2.60e-01 75.9% 46.9%
2i9xA00 3.30.1120.40 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Stage V sporulation protein G 0.51 37.0 3.28e-01 81.5% 66.3%
3t0pA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.50 36.0 2.62e-01 90.7% 22.8%
3nuwA01 3.30.420.300 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, substrate binding domain 0.50 35.0 3.15e-01 79.6% 77.8%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
152420 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.97 91.0 5.14e-01 100.0% 11.1%
2833528 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.94 82.0 4.64e-01 100.0% 10.3%
4889672 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.92 80.0 4.59e-01 100.0% 11.5%
1112626 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.89 76.0 4.40e-01 100.0% 11.4%
2527935 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.88 76.0 4.37e-01 100.0% 11.6%
1563144 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.88 81.0 4.61e-01 100.0% 11.8%
1519176 5.1.3.5 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › HN 0.81 68.0 3.97e-01 100.0% 12.0%
4982545 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.67 58.0 5.05e-01 98.1% 71.4%
3032521 5.1.3.26 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › BNR_2 0.64 52.0 3.23e-01 100.0% 15.1%
3935989 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.61 47.0 2.84e-01 100.0% 12.5%
4978676 295.1.1.1 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PC4 0.61 50.0 4.51e-01 100.0% 65.0%
3589823 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.61 46.0 4.41e-01 85.2% 70.8%
4947855 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.61 50.0 2.97e-01 96.3% 17.5%
4138644 5.1.3.19 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Hira 0.60 47.0 3.15e-01 100.0% 20.4%
3997948 10.1.1.4 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin 0.60 48.0 3.50e-01 100.0% 31.6%
3480732 11.1.5.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.59 45.0 3.73e-01 88.9% 99.1%
3258445 7089.1.1.0 ↗ a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.58 41.0 4.31e-01 87.0% 91.1%
3272078 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.58 44.0 2.88e-01 90.7% 19.3%
3508738 10.1.1.4 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin 0.57 48.0 3.63e-01 100.0% 37.1%
2320613 10.1.1.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.57 49.0 3.29e-01 100.0% 24.9%
3928764 11.1.1.53 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DOMON 0.56 48.0 3.95e-01 100.0% 57.1%
3819893 5.1.4.288 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › APEH_N 0.56 47.0 2.77e-01 96.3% 14.5%
4847379 5.1.5.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.56 41.0 2.64e-01 100.0% 14.9%
3300968 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.55 44.0 2.51e-01 100.0% 46.9%
3185314 10.1.1.16 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Peptidase_A4 0.55 44.0 3.05e-01 100.0% 23.8%
3501354 10.1.1.35 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_3 0.54 46.0 3.03e-01 100.0% 22.4%
3359021 5.1.5.86 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Kelch_1 0.54 43.0 2.80e-01 100.0% 17.0%
4978599 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.54 42.0 2.63e-01 96.3% 13.7%
3963566 4056.1.1.5 ↗ beta barrels › Barrel domain in upper collar protein › Barrel domain in upper collar protein › Barrel domain in upper collar protein › P22_portal 0.54 45.0 3.43e-01 100.0% 58.4%
3242315 145.1.1.0 ↗ alpha arrays › F-box domain › F-box domain › F-box domain 0.54 44.0 4.39e-01 100.0% 90.9%
3622366 295.1.1.0 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.53 41.0 4.24e-01 90.7% 96.0%
5009292 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.53 39.0 2.60e-01 88.9% 17.9%
3290202 1001.1.1.1 ↗ a+b two layers › Formate dehydrogenase/DMSO reductase, domain 1 › Formate dehydrogenase/DMSO reductase, domain 1 › Formate dehydrogenase/DMSO reductase, domain 1 › Molybdop_Fe4S4 0.53 37.0 3.66e-01 88.9% 66.7%
3711463 5.1.4.14 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Peptidase_S9_N 0.53 42.0 2.65e-01 98.1% 26.9%
3493109 5.1.4.275 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, ANAPC4_WD40, Beta-prop_NOL10_N 0.52 43.0 2.66e-01 100.0% 16.5%
3780836 5.1.4.257 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP, FG-GAP_3 0.52 42.0 2.61e-01 100.0% 14.4%
3968468 4152.2.1.0 ↗ a+b two layers › Shew3726-like › Uncharacterized protein CV_2116 › Uncharacterized protein CV_2116 0.52 40.0 3.71e-01 94.4% 65.3%
3404225 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.51 36.0 2.57e-01 79.6% 29.5%
3685667 4210.1.1.1 ↗ a+b two layers › WGR domain › WGR domain › WGR domain › WGR 0.51 42.0 3.40e-01 100.0% 45.8%
3954760 1001.1.1.1 ↗ a+b two layers › Formate dehydrogenase/DMSO reductase, domain 1 › Formate dehydrogenase/DMSO reductase, domain 1 › Formate dehydrogenase/DMSO reductase, domain 1 › Molybdop_Fe4S4 0.51 37.0 3.60e-01 83.3% 73.3%
4969580 2484.1.1.43 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Endonuclease_5 0.50 36.0 2.46e-01 77.8% 90.0%
4992254 11.1.4.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.50 36.0 3.59e-01 100.0% 78.2%