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highly_derived_D5-like_helicase-primase

Euk-Vir

Tunisvirus_fontaine2

highly_derived_D5-like_helicase-primase__YP_009507125__Tunisvirus_fontaine2__1421067

Identity

Accession:
YP_009507125 ↗
Protein ID:
highly_derived_D5-like_helicase-primase
Kingdom:
euk

Quality

71.7 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Losannavirus› Tunisvirus_fontaine2

TaxID: 1421067

Cluster

View cluster (4 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 18-93
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1s6lA02 3.15.10.60 Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Alkylmercury lyase 0.66 54.0 4.54e-01 89.5% 76.0%
2p5vA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.61 44.0 4.26e-01 75.0% 100.0%
4iajA00 3.30.1490.390 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Protein of unknown function DUF4649 0.60 38.0 3.85e-01 72.4% 63.2%
2cyyA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.60 44.0 4.13e-01 78.9% 87.4%
3h41A03 3.90.1720.10 Alpha Beta › Alpha-Beta Complex › endopeptidase fold (from Nostoc punctiforme) › endopeptidase domain like (from Nostoc punctiforme) 0.56 46.0 3.97e-01 92.1% 82.5%
2pw9C03 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.56 44.0 3.65e-01 86.8% 61.6%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 35.0 3.73e-01 96.1% 74.2%
1hskA01 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.54 38.0 3.30e-01 75.0% 81.9%
1s4dE02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.54 45.0 3.71e-01 92.1% 95.7%
3hh7A00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.54 37.0 3.98e-01 89.5% 84.6%
1ywhC03 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.53 43.0 4.11e-01 90.8% 89.8%
3ffyA00 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.51 40.0 3.56e-01 86.8% 94.6%
4bwiB02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.50 40.0 3.20e-01 94.7% 86.5%
4ekuA01 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.50 34.0 3.04e-01 72.4% 54.7%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3610883 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.79 69.0 4.40e-01 97.4% 21.5%
3717917 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.79 66.0 4.14e-01 97.4% 18.7%
3512046 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.73 59.0 4.01e-01 92.1% 25.5%
2756948 862.1.1.1 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.72 55.0 4.14e-01 92.1% 34.1%
3717098 862.1.1.7 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › PPL5 0.66 57.0 3.82e-01 94.7% 30.7%
4987580 304.4.1.1 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg 0.58 43.0 4.14e-01 80.3% 91.1%
4981868 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.58 45.0 4.25e-01 82.9% 92.2%
3666940 821.1.1.1 ↗ a+b three layers › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG endonuclease › GIY-YIG 0.58 49.0 4.25e-01 94.7% 98.3%
5044110 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.57 39.0 3.47e-01 72.4% 69.6%
3782443 377.1.1.0 ↗ few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like 0.57 40.0 3.20e-01 85.5% 35.2%
3766042 221.1.1.76 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RA_2 0.56 34.0 3.08e-01 71.1% 40.9%
4478659 3435.1.1.3 ↗ a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › CENP-L 0.55 41.0 2.77e-01 78.9% 85.9%
146929 3115.3.1.1 ↗ a+b two layers › GP2-like › P56 › P56 › UDG-inhib_P56 0.55 38.0 4.17e-01 75.0% 96.4%
5077548 210.1.3.0 ↗ a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases 0.55 47.0 3.24e-01 100.0% 88.1%
5075438 304.4.1.29 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 0.55 39.0 3.76e-01 100.0% 65.9%
5045774 2492.1.1.7 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.55 43.0 3.58e-01 86.8% 61.4%
3590928 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.55 37.0 3.88e-01 92.1% 80.0%
5065792 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.55 38.0 3.13e-01 75.0% 46.5%
5047755 2492.1.1.7 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.54 43.0 3.53e-01 86.8% 62.1%
5004227 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.54 41.0 2.99e-01 85.5% 76.0%
3268696 224.1.1.0 ↗ a+b three layers › Gelsolin-like › Gelsolin-like › Gelsolin-like 0.54 44.0 3.66e-01 100.0% 49.3%
5027350 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.54 40.0 3.36e-01 81.6% 50.7%
5020151 2492.1.1.7 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › FdhD-NarQ 0.52 41.0 3.45e-01 86.8% 63.0%
5081419 210.1.3.3 ↗ a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_4 0.52 40.0 2.85e-01 86.8% 72.6%
3909937 382.1.1.2 ↗ few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like › Toxin_TOLIP 0.52 39.0 3.78e-01 100.0% 72.6%
3878052 382.1.1.0 ↗ few secondary structure elements › Snake toxin-like › Snake toxin-like › Snake toxin-like 0.52 40.0 3.86e-01 100.0% 74.1%
4939880 315.1.1.15 ↗ a+b two layers › Tautomerase/MIF-like › Tautomerase/MIF › Tautomerase/MIF › DUF5402 0.51 39.0 3.38e-01 85.5% 83.8%
3340123 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.51 35.0 3.34e-01 75.0% 60.0%
3504586 301.1.1.2 ↗ a+b three layers › Bacillus chorismate mutase-like › L30e-like › L30e-like › eRF1_3 0.51 39.0 3.11e-01 81.6% 41.9%
3250122 376.1.1.0 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box 0.50 38.0 3.57e-01 85.5% 64.0%
D2 high residues 727-802
PDB
Domain cluster: rep: MK764448.1__QCW20633.1__X__00003__D396-466
D3 medium residues 99-196_217-242
PDB
Domain cluster: rep: hypothetical_protein_H012_gp354__YP_007354538__Acanthamoeba_polyphaga_moumouvirus__1269028__D9-184
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 45.0 5.23e-01 79.0% 92.9%
3udcA03 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 47.0 5.43e-01 75.8% 97.7%
1vqzA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.68 52.0 4.11e-01 79.8% 62.4%
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.68 57.0 4.48e-01 91.9% 94.4%
3uebF00 3.30.300.100 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like 0.67 49.0 5.35e-01 75.8% 93.0%
1m55A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.67 56.0 4.85e-01 90.3% 90.2%
3p96A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 43.0 5.05e-01 95.2% 96.4%
2lu1A00 3.30.70.2370 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 43.0 4.96e-01 79.0% 93.3%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.64 49.0 5.31e-01 88.7% 98.1%
3pcoB06 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.63 44.0 4.96e-01 79.0% 94.7%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.63 47.0 4.71e-01 97.6% 75.4%
4mt1A03 3.30.70.1320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like 0.63 46.0 5.09e-01 93.5% 96.9%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.63 43.0 4.56e-01 94.4% 79.8%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.63 47.0 5.02e-01 79.0% 91.7%
5t0oA03 3.30.70.1320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like 0.62 45.0 4.93e-01 79.0% 94.1%
3b49A00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.62 52.0 4.46e-01 91.9% 86.3%
3u5eU00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.62 42.0 4.62e-01 79.0% 87.0%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.61 46.0 4.82e-01 94.4% 87.5%
6wubf01 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.61 44.0 5.00e-01 94.4% 100.0%
4wxaA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.61 37.0 4.29e-01 75.8% 88.1%
3fmbA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.94e-01 96.0% 98.0%
2govA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.60 51.0 4.55e-01 91.9% 86.1%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.59 49.0 5.09e-01 96.8% 95.8%
1q8bA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 42.0 4.71e-01 96.0% 100.0%
2y1rK00 3.30.70.1950 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 38.0 4.27e-01 91.1% 89.1%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.58 50.0 4.70e-01 94.4% 86.2%
4c8yA01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 45.0 4.77e-01 95.2% 99.0%
3w3sA01 3.30.70.1920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 45.0 4.07e-01 97.6% 61.3%
3ekiA01 3.40.190.180 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Cypl, domain I 0.57 43.0 3.85e-01 78.2% 84.1%
4cyuA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.57 50.0 4.65e-01 95.2% 84.4%
3otdA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.57 52.0 4.17e-01 100.0% 91.3%
1ab8A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.57 49.0 4.40e-01 95.2% 74.0%
3r8jA00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.57 47.0 4.19e-01 90.3% 81.1%
2g47A04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 50.0 4.03e-01 96.8% 72.1%
2rkvA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.57 48.0 4.04e-01 92.7% 91.6%
5wpjA02 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.57 45.0 4.78e-01 96.0% 100.0%
2abyA00 3.30.70.1980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF09406, DUF2004 0.57 45.0 4.57e-01 84.7% 90.2%
6ofsA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 48.0 4.30e-01 96.0% 93.5%
3bn7A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 43.0 4.63e-01 95.2% 99.0%
8es5A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.56 41.0 3.98e-01 76.6% 95.7%
2wz1B00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.56 48.0 4.16e-01 95.2% 64.8%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.56 46.0 4.25e-01 91.1% 81.8%
6usmB01 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.55 48.0 4.57e-01 95.2% 88.4%
1azsA00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.55 48.0 4.15e-01 95.2% 63.7%
1xmbA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 4.57e-01 100.0% 99.0%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 42.0 4.54e-01 98.4% 100.0%
2exuA02 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.55 38.0 4.29e-01 87.1% 96.8%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 47.0 3.95e-01 96.0% 84.5%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.54 47.0 3.96e-01 96.0% 83.4%
4dmzA02 3.30.70.2880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 46.0 4.48e-01 92.7% 83.9%
2l8oA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 41.0 3.92e-01 79.0% 91.0%
3mcsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 46.0 3.87e-01 96.8% 98.1%
2kcuA00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.53 44.0 4.01e-01 90.3% 81.3%
4c98A01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 39.0 4.23e-01 96.8% 96.2%
1vdhA01 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.51 39.0 3.95e-01 97.6% 81.8%
3gqcC01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.51 46.0 4.44e-01 97.6% 92.7%
1fnoA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 42.0 4.41e-01 96.0% 100.0%
2dgkA02 3.90.1150.160 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.51 36.0 3.88e-01 89.5% 85.0%
1v5vA01 3.30.1360.120 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Probable tRNA modification gtpase trme; domain 1 0.51 39.0 3.60e-01 80.6% 81.1%
1zr6A03 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.50 41.0 3.56e-01 90.3% 75.9%
3rjaA02 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.50 40.0 3.37e-01 88.7% 65.9%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3802060 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.89 85.0 6.48e-01 100.0% 67.8%
3677440 862.1.1.11 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R 0.88 84.0 6.51e-01 100.0% 70.6%
4030726 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.88 84.0 6.15e-01 100.0% 65.2%
3492512 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.88 84.0 5.96e-01 100.0% 67.2%
3512046 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.87 83.0 6.35e-01 100.0% 69.8%
3937694 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.86 82.0 6.21e-01 100.0% 67.2%
4001493 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.86 82.0 6.38e-01 100.0% 71.2%
3626314 862.1.1.11 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › AEP_C962R 0.86 82.0 6.29e-01 100.0% 68.4%
4673704 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.86 81.0 6.06e-01 100.0% 61.1%
2756948 862.1.1.1 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.84 61.0 5.26e-01 77.4% 50.5%
3719042 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.80 76.0 6.00e-01 100.0% 68.3%
3608399 862.1.1.7 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › PPL5 0.80 76.0 5.96e-01 100.0% 66.8%
3598810 862.1.1.0 ↗ a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.73 67.0 5.79e-01 96.8% 79.4%
5055979 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.71 49.0 5.46e-01 78.2% 91.6%
3268447 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.68 50.0 5.33e-01 78.2% 88.6%
3702849 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.67 50.0 5.43e-01 84.7% 92.4%
3602951 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.67 47.0 5.08e-01 78.2% 85.7%
3223328 304.8.1.78 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF7637 0.66 50.0 5.40e-01 96.0% 94.3%
5074889 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.66 47.0 5.29e-01 73.4% 98.9%
3590830 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.66 46.0 5.15e-01 78.2% 94.7%
3220212 304.12.1.11 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › DUF7637 0.65 50.0 5.30e-01 96.0% 91.8%
4273051 304.7.1.2 ↗ a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 0.65 42.0 4.63e-01 79.0% 80.0%
4970926 304.20.1.0 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.65 55.0 4.79e-01 91.1% 88.6%
3236767 4955.1.1.0 ↗ a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.65 44.0 5.00e-01 70.2% 100.0%
3597457 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.65 44.0 4.94e-01 75.8% 91.6%
3591115 304.163.1.0 ↗ a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.65 48.0 5.31e-01 95.2% 97.0%
984477 878.1.1.1 ↗ a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 0.65 47.0 5.18e-01 75.8% 96.0%
5046168 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.65 47.0 3.83e-01 79.0% 40.3%
3306490 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.64 47.0 4.97e-01 78.2% 85.5%
3210886 304.8.1.78 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › DUF7637 0.64 50.0 5.34e-01 95.2% 97.1%
3231858 304.8.1.72 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › SCVP 0.64 46.0 5.02e-01 94.4% 93.0%
3962699 309.1.1.4 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.64 45.0 4.23e-01 75.0% 58.7%
4979336 304.20.1.0 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.63 54.0 4.79e-01 91.9% 90.3%
5017844 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.63 48.0 4.91e-01 79.0% 88.3%
4996727 304.39.1.1 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.63 47.0 4.87e-01 78.2% 91.3%
3615120 375.1.1.207 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › FAZ1_cons 0.63 43.0 4.83e-01 75.0% 96.7%
4949748 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.63 47.0 4.70e-01 78.2% 84.0%
4944179 304.43.1.0 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.62 47.0 5.12e-01 95.2% 98.0%
3703734 304.55.2.8 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › FAZ1_cons 0.62 42.0 4.76e-01 75.8% 95.6%
3963252 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.62 46.0 4.99e-01 94.4% 92.4%
3609886 304.47.1.0 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.62 44.0 4.83e-01 75.8% 91.0%
3737531 304.9.1.1 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 48.0 4.04e-01 83.1% 53.3%
3750557 304.47.1.0 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain 0.61 51.0 5.30e-01 95.2% 98.3%
3705400 304.31.1.3 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › FAZ1_cons 0.61 43.0 4.72e-01 75.8% 93.7%
3881181 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.61 54.0 5.13e-01 96.8% 88.3%
3897523 304.12.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.60 45.0 4.59e-01 95.2% 80.8%
3601349 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 49.0 2.91e-01 86.3% 40.2%
3918855 304.47.1.1 ↗ a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.60 47.0 4.88e-01 93.5% 90.4%
3839278 304.15.1.0 ↗ a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.60 47.0 4.78e-01 94.4% 85.8%
2443924 304.51.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.60 46.0 4.91e-01 96.0% 96.2%
3971826 309.1.1.4 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.59 51.0 4.37e-01 95.2% 79.0%
3934872 3122.1.1.2 ↗ a+b complex topology › MESD › MESD › MESD › SCVP 0.59 43.0 4.61e-01 94.4% 89.5%
3965604 304.39.1.0 ↗ a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.59 43.0 4.51e-01 76.6% 86.1%
1146572 304.152.1.1 ↗ a+b two layers › Alpha-beta plaits › E4-ORF3 › E4-ORF3 › Adeno_E4_ORF3 0.59 50.0 5.19e-01 96.8% 100.0%
5044457 304.20.1.0 ↗ a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.59 49.0 4.56e-01 91.9% 93.1%
3488179 3501.1.1.1 ↗ a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.59 37.0 4.18e-01 77.4% 86.7%
4964003 241.1.1.29 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › DUF5813 0.59 44.0 4.11e-01 78.2% 65.8%
4599652 304.162.1.1 ↗ a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.59 37.0 4.26e-01 77.4% 95.0%
2529479 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.59 49.0 4.06e-01 90.3% 71.7%
4969505 304.51.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.58 47.0 4.90e-01 95.2% 98.2%
3588477 304.31.1.1 ↗ a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red 0.58 47.0 4.99e-01 95.2% 100.0%
3702245 304.110.1.7 ↗ a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › TEX47 0.57 47.0 4.05e-01 90.3% 75.6%
4939612 304.51.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.57 46.0 4.77e-01 95.2% 94.8%
3609299 304.110.1.7 ↗ a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › TEX47 0.57 47.0 4.02e-01 89.5% 75.5%
1183124 309.1.1.11 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.57 49.0 4.00e-01 96.8% 71.5%
5002487 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.56 44.0 4.31e-01 96.8% 77.0%
4996591 309.1.2.2 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › tRNA_bind_4 0.56 44.0 3.95e-01 96.8% 60.0%
3601534 309.1.1.0 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.56 49.0 4.16e-01 96.8% 78.0%
3592453 304.110.1.0 ↗ a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like 0.55 46.0 3.97e-01 90.3% 75.4%
5033589 304.25.1.1 ↗ a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.55 45.0 3.77e-01 99.2% 51.2%
4018783 390.1.1.0 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.55 35.0 3.83e-01 88.7% 79.0%
4074059 309.1.1.0 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.55 48.0 4.17e-01 96.8% 82.0%
3428361 304.159.1.2 ↗ a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › DUF3531 0.54 44.0 4.43e-01 88.7% 93.0%
None — 0.54 48.0 4.50e-01 98.4% 82.4%
4229813 304.6.1.3 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.54 45.0 3.49e-01 89.5% 56.6%
3613400 304.51.1.0 ↗ a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.54 45.0 4.62e-01 93.5% 99.2%
2978967 309.1.1.0 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.53 46.0 3.91e-01 96.8% 83.3%
3235660 304.151.1.4 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › PF25899 0.53 45.0 4.53e-01 94.4% 100.0%
3413369 304.151.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase 0.52 44.0 4.37e-01 94.4% 92.3%
3332187 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.51 40.0 3.08e-01 83.9% 91.6%
3717360 244.1.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.51 43.0 4.36e-01 93.5% 99.2%
D4 medium residues 264-352
PDB
D5 medium residues 526-548_581-600_669-726
PDB
Domain cluster: rep: highly_derived_D5-like_helicase-primase__YP_009238567__Brazilian_marseillevirus__1813599__D506-551_660-682_703-729
D6 medium residues 549-580_601-668
PDB
Domain cluster: rep: highly_derived_D5-like_helicase-primase__YP_003406787__Marseillevirus_marseillevirus__694581__D555-677
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF19263.6 best DUF5906 44.8 2.50e-11 72.0% 57.5%