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hypothetical_protein_2
Euk-VirWuhan_insect_virus_26
hypothetical_protein_2__YP_009342428__Wuhan_insect_virus_26__1923730
Identity
- Accession:
- YP_009342428 ↗
- Protein ID:
- hypothetical_protein_2
- Kingdom:
- euk
Quality
71.3
mean pLDDT
Taxonomy
Orthornavirae›
Duplornaviricota›
Chrymotiviricetes›
Ghabrivirales›
Orthototiviridae›
Totivirus›
Wuhan_insect_virus_26
TaxID: 1923730
Cluster
View cluster (56 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 36-94
D2
high
residues 160-264_593-613
Domain cluster:
rep: hypothetical_protein_2__YP_009342434__Wuhan_insect_virus_27__1923731__D156-254
D3
high
residues 270-435_448-536
Domain cluster:
rep: hypothetical_protein_2__YP_009336713__Beihai_toti-like_virus_4__1922734__D167-187_213-323_360-427
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02123.22 best | RdRP_4 | 105.7 | 4.20e-30 | 99.6% | 45.4% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.76 | 72.0 | 5.62e-01 | 100.0% | 68.0% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5366 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.76 | 73.0 | 6.15e-01 | 100.0% | 69.8% |
| 223786 | 304.48.1.16 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_4 | 0.75 | 71.0 | 6.51e-01 | 100.0% | 85.4% |
| 3928801 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.73 | 69.0 | 6.12e-01 | 100.0% | 80.9% |
| 3772920 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.72 | 67.0 | 6.35e-01 | 99.2% | 92.0% |
| 3260077 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 67.0 | 5.75e-01 | 100.0% | 73.1% |
| 3273928 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 67.0 | 5.07e-01 | 100.0% | 50.2% |
| 3272030 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 67.0 | 5.70e-01 | 100.0% | 72.2% |
| 3920615 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 67.0 | 5.42e-01 | 100.0% | 62.9% |
| 3265091 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 66.0 | 5.05e-01 | 100.0% | 50.6% |
| 4108146 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 58.0 | 5.21e-01 | 85.5% | 69.0% |
| 3784946 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 66.0 | 5.57e-01 | 100.0% | 68.7% |
| 3878013 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 66.0 | 5.61e-01 | 100.0% | 71.0% |
| 3899435 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 66.0 | 5.39e-01 | 100.0% | 64.0% |
| 3939319 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.69 | 65.0 | 5.56e-01 | 100.0% | 77.0% |
| 4516798 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.69 | 59.0 | 4.78e-01 | 89.0% | 50.5% |
| 4380832 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.69 | 65.0 | 5.54e-01 | 100.0% | 67.1% |
| 3422064 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.67 | 64.0 | 5.42e-01 | 100.0% | 71.6% |
| 3615272 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.67 | 59.0 | 5.10e-01 | 92.5% | 73.2% |
| 3574984 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.67 | 63.0 | 5.47e-01 | 100.0% | 70.9% |
| 3598902 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.66 | 58.0 | 5.05e-01 | 92.5% | 73.7% |
| 2636124 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.63 | 44.0 | 4.57e-01 | 100.0% | 75.6% |
| 3792091 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.63 | 55.0 | 4.91e-01 | 91.4% | 74.2% |
| 4296494 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.57 | 47.0 | 4.44e-01 | 98.4% | 72.1% |
| 3708776 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.51 | 48.0 | 4.36e-01 | 97.6% | 79.7% |
D4
medium
residues 436-447_537-592
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02123.22 best | RdRP_4 | 35.2 | 1.00e-08 | 100.0% | 12.0% |
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ol8A01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.72 | 62.0 | 4.99e-01 | 97.1% | 68.9% |
| 4kyzA00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.68 | 49.0 | 3.74e-01 | 77.9% | 47.3% |
| 7npaA02 | 3.30.70.3340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 46.0 | 4.34e-01 | 72.1% | 81.2% |
| 6s2wA01 | 3.30.2260.10 | Alpha Beta › 2-Layer Sandwich › ERH-like fold › Enhancer of rudimentary | 0.63 | 47.0 | 4.41e-01 | 79.4% | 80.5% |
| 3rgzA02 | 3.30.1490.310 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › | 0.63 | 47.0 | 4.88e-01 | 95.6% | 90.2% |
| 4llgM00 | 3.10.20.510 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › RNA polymerase inhibitor | 0.61 | 42.0 | 4.64e-01 | 94.1% | 100.0% |
| 1ln0A00 | 3.40.1440.10 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease | 0.58 | 46.0 | 4.20e-01 | 86.8% | 87.0% |
| 1lfpA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.58 | 49.0 | 4.85e-01 | 95.6% | 95.9% |
| 4mz0B05 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.58 | 43.0 | 4.39e-01 | 80.9% | 98.5% |
| 2cuwA00 | 3.30.1280.10 | Alpha Beta › 2-Layer Sandwich › Mth169; Chain: A , › Phosphoribosylformylglycinamidine synthase subunit PurS | 0.57 | 43.0 | 4.03e-01 | 80.9% | 96.4% |
| 4njcA00 | 3.10.20.730 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › RNAP, epsilon subunit-like | 0.54 | 39.0 | 4.12e-01 | 80.9% | 88.3% |
| 3gbwA00 | 2.60.120.820 | Mainly Beta › Sandwich › Jelly Rolls › PHR domain | 0.53 | 38.0 | 3.01e-01 | 77.9% | 77.0% |
| 1qysA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.52 | 43.0 | 3.95e-01 | 92.6% | 90.2% |
| 3hvnA01 | 3.90.840.10 | Alpha Beta › Alpha-Beta Complex › HIV-1 Reverse Transcriptase; Chain A, domain 3 › Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain | 0.52 | 44.0 | 3.39e-01 | 100.0% | 66.9% |
| 2qruA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.51 | 41.0 | 2.84e-01 | 94.1% | 89.7% |
| 1kbaA00 | 2.10.60.10 | Mainly Beta › Ribbon › CD59 › CD59 | 0.50 | 33.0 | 3.40e-01 | 80.9% | 69.7% |
ECOD (32)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3279061 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.80 | 59.0 | 5.90e-01 | 77.9% | 97.1% |
| 4996340 | 304.8.1.2 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT | 0.78 | 57.0 | 5.40e-01 | 76.5% | 100.0% |
| 4961982 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.77 | 55.0 | 5.84e-01 | 75.0% | 98.3% |
| 5080144 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.74 | 56.0 | 5.63e-01 | 80.9% | 97.1% |
| 4949784 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.72 | 53.0 | 5.46e-01 | 79.4% | 100.0% |
| 3589438 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.72 | 55.0 | 5.80e-01 | 80.9% | 100.0% |
| 5011383 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.70 | 53.0 | 5.64e-01 | 91.2% | 91.7% |
| 5071118 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.69 | 50.0 | 5.15e-01 | 77.9% | 100.0% |
| 4981449 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.67 | 59.0 | 5.73e-01 | 97.1% | 100.0% |
| 5040784 | 304.163.1.0 ↗ | a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain | 0.65 | 45.0 | 5.07e-01 | 77.9% | 100.0% |
| 4977215 | 304.117.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC | 0.65 | 44.0 | 4.63e-01 | 70.6% | 100.0% |
| 5041711 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.64 | 54.0 | 5.35e-01 | 91.2% | 100.0% |
| 4957781 | 807.1.1.0 ↗ | a+b two layers › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) | 0.64 | 45.0 | 5.02e-01 | 75.0% | 100.0% |
| 5049182 | 3435.1.1.0 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC | 0.61 | 53.0 | 3.67e-01 | 100.0% | 87.1% |
| 4642338 | 807.1.1.1 ↗ | a+b two layers › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) › CpcD | 0.61 | 42.0 | 4.53e-01 | 77.9% | 92.5% |
| 4949196 | 304.117.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC | 0.59 | 48.0 | 5.02e-01 | 91.2% | 100.0% |
| 3634674 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.59 | 49.0 | 3.11e-01 | 94.1% | 66.3% |
| 3517068 | 3115.1.1.6 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › DUF4494 | 0.57 | 41.0 | 4.25e-01 | 77.9% | 86.2% |
| 3679804 | 207.1.1.365 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_1, LRR_8, Island, LRR_14 | 0.57 | 50.0 | 3.00e-01 | 100.0% | 21.0% |
| 5025087 | 101.1.11.0 ↗ | alpha arrays › HTH › HTH › Ribbon-helix-helix | 0.57 | 40.0 | 4.21e-01 | 75.0% | 98.3% |
| 2886666 | 807.1.1.1 ↗ | a+b two layers › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) › Allophycocyanin linker chain (domain) › CpcD | 0.57 | 42.0 | 3.37e-01 | 92.6% | 39.4% |
| 5012895 | 3115.1.1.0 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like | 0.56 | 40.0 | 4.32e-01 | 77.9% | 94.5% |
| 4024270 | 4263.2.1.1 ↗ | a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain › FtsH_ext | 0.56 | 40.0 | 3.81e-01 | 75.0% | 66.3% |
| 3264069 | 822.1.1.2 ↗ | a+b two layers › GYF/BRK domain-like › GYF domain › GYF domain › GYF_2 | 0.53 | 38.0 | 4.00e-01 | 82.4% | 86.7% |
| 3484366 | 284.1.2.1 ↗ | a+b two layers › FKBP-like › FKBP-like › Conserved carboxy-terminal domain of oxidative-stress-responsive kinase 1-like kinases › OSR1_C | 0.53 | 43.0 | 3.88e-01 | 92.6% | 98.0% |
| 3732330 | 2484.1.1.192 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF8340_N | 0.53 | 42.0 | 2.87e-01 | 89.7% | 93.5% |
| 3428850 | 376.1.1.50 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › DUF1644 | 0.52 | 39.0 | 3.48e-01 | 95.6% | 53.3% |
| 3945340 | 235.1.1.9 ↗ | a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › SLT | 0.52 | 45.0 | 3.54e-01 | 100.0% | 81.3% |
| 4969863 | 3115.1.1.1 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A | 0.52 | 43.0 | 4.18e-01 | 91.2% | 90.7% |
| 3628891 | 2492.1.1.0 ↗ | a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like | 0.51 | 43.0 | 3.66e-01 | 100.0% | 76.0% |
| 5067865 | 3115.1.1.0 ↗ | a+b two layers › GP2-like › RplX-like › RplX-like | 0.50 | 42.0 | 4.23e-01 | 95.6% | 90.0% |
| 5075731 | 3435.1.1.0 ↗ | a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC | 0.50 | 40.0 | 3.60e-01 | 92.6% | 61.9% |
D5
medium
residues 637-812
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1td6A01 | 1.20.1480.10 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › hypothetical protein mp506/mpn330, domain 1 | 0.51 | 21.0 | 2.74e-01 | 76.7% | 63.7% |