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hypothetical_protein_2

Euk-Vir

Wuhan_insect_virus_27

hypothetical_protein_2__YP_009342434__Wuhan_insect_virus_27__1923731

Identity

Accession:
YP_009342434 ↗
Protein ID:
hypothetical_protein_2
Kingdom:
euk

Quality

71.7 mean pLDDT

Taxonomy

Orthornavirae› Duplornaviricota› Chrymotiviricetes› Ghabrivirales› Orthototiviridae› Totivirus› Wuhan_insect_virus_27

TaxID: 1923731

Cluster

View cluster (56 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 26-84
PDB
D2 medium residues 156-254
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rldA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.68 48.0 4.64e-01 73.7% 95.6%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.67 53.0 4.65e-01 84.8% 82.7%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.67 48.0 4.81e-01 74.7% 99.0%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 51.0 4.27e-01 85.9% 74.9%
3k2jA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.64 47.0 4.43e-01 77.8% 91.7%
2yqdA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.64 47.0 4.44e-01 77.8% 87.5%
1eqfA02 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.63 47.0 4.36e-01 78.8% 86.4%
2gfpA00 1.20.1720.10 Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D 0.62 44.0 2.99e-01 73.7% 45.1%
6dkuA01 1.10.8.950 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Filoviridae VP35, C-terminal inhibitory domain, helical subdomain 0.62 42.0 4.75e-01 79.8% 94.5%
6h9dA00 1.10.530.40 Mainly Alpha › Orthogonal Bundle › Lysozyme › 0.62 54.0 4.76e-01 99.0% 98.0%
3mvuA00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.60 47.0 3.70e-01 85.9% 59.8%
4m0mA04 1.20.1270.440 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 42.0 4.05e-01 76.8% 94.9%
4hteA01 1.20.58.1730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 38.0 3.36e-01 72.7% 45.5%
1su0B00 3.90.1010.10 Alpha Beta › Alpha-Beta Complex › Sufe protein. Chain: A › 0.58 47.0 4.25e-01 87.9% 89.7%
3u61D03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.58 31.0 3.29e-01 89.9% 56.0%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.53 47.0 4.59e-01 99.0% 97.3%
4tpjA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 45.0 3.02e-01 98.0% 86.5%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 45.0 3.88e-01 100.0% 60.4%
4ehsA00 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.51 38.0 3.53e-01 76.8% 88.7%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.50 39.0 3.44e-01 82.8% 84.2%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3782069 633.21.1.0 ↗ alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.73 52.0 4.69e-01 73.7% 91.1%
3536246 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.71 50.0 4.43e-01 73.7% 91.0%
3596713 633.1.1.0 ↗ alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.66 48.0 4.38e-01 77.8% 86.7%
3957198 283.1.1.0 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase 0.61 50.0 3.65e-01 91.9% 92.9%
4293088 2498.1.1.10 ↗ mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 0.51 42.0 3.11e-01 93.9% 82.8%
3705521 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 42.0 3.63e-01 90.9% 85.2%
D3 medium residues 275-301_438-483
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.67 59.0 4.58e-01 95.9% 98.7%
3d8uB02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.66 51.0 3.98e-01 90.4% 40.0%
6ljaA01 1.50.10.100 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Chondroitin AC/alginate lyase 0.64 49.0 3.13e-01 82.2% 42.8%
2vm6A00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.62 49.0 4.03e-01 89.0% 68.1%
3tl4X02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.62 42.0 4.32e-01 71.2% 94.4%
4iu9B01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.62 53.0 3.82e-01 100.0% 48.7%
3sl1A00 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.60 52.0 3.42e-01 94.5% 57.1%
1e5rB02 1.10.1720.10 Mainly Alpha › Orthogonal Bundle › Proline Oxidase; Chain: A, Domain 2 › L-proline 3-hydroxylase, C-terminal domain 0.60 47.0 4.54e-01 86.3% 88.1%
8e9gK01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.59 44.0 4.13e-01 79.5% 81.3%
3k8pC02 1.10.357.150 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.59 50.0 3.84e-01 100.0% 68.4%
3f0cA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.59 48.0 3.98e-01 94.5% 77.1%
3obwA02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.59 40.0 3.51e-01 80.8% 44.9%
2pkeA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.59 41.0 4.03e-01 82.2% 67.9%
7eu3E01 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 45.0 4.25e-01 82.2% 83.9%
3b81A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 47.0 3.68e-01 97.3% 57.9%
2h3hB02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.57 46.0 3.61e-01 87.7% 47.1%
2lmgA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.57 42.0 4.25e-01 90.4% 77.0%
2j9wB00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.56 40.0 3.70e-01 76.7% 76.8%
3owaB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 46.0 3.55e-01 90.4% 89.8%
7zm7601 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.55 43.0 3.36e-01 86.3% 96.4%
2hujA00 1.20.120.440 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like 0.55 42.0 3.55e-01 82.2% 74.4%
2oqhA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.54 47.0 3.24e-01 97.3% 35.4%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 44.0 3.59e-01 95.9% 75.0%
4m88A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 39.0 3.18e-01 83.6% 42.7%
3kdzA01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.51 43.0 3.14e-01 91.8% 79.8%
4ip8A00 1.10.132.110 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Serum amyloid A protein 0.50 42.0 3.76e-01 93.2% 81.0%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1144728 604.12.1.2 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.72 53.0 4.83e-01 76.7% 91.5%
3281805 191.1.1.0 ↗ alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.71 61.0 4.87e-01 91.8% 72.6%
4947323 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.67 46.0 4.05e-01 71.2% 67.6%
4011775 109.4.1.2139 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26001 0.67 55.0 4.06e-01 91.8% 51.8%
3437958 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 54.0 3.87e-01 90.4% 60.0%
3700624 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.64 53.0 4.06e-01 91.8% 53.9%
3227288 206.1.1.28 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.63 43.0 3.28e-01 71.2% 71.1%
4340169 601.3.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.62 43.0 3.65e-01 72.6% 53.7%
3971927 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.61 47.0 4.49e-01 80.8% 90.5%
3988294 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 49.0 3.58e-01 90.4% 71.4%
3655867 109.4.1.1411 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30303 0.60 47.0 3.75e-01 87.7% 75.6%
3471984 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 45.0 3.99e-01 80.8% 73.3%
3880207 109.25.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A 0.59 46.0 4.01e-01 86.3% 76.5%
4281647 7014.1.1.1 ↗ alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.59 47.0 3.73e-01 90.4% 61.3%
3714860 2003.4.1.1 ↗ a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP 0.59 48.0 3.36e-01 89.0% 38.7%
4621040 7014.1.1.1 ↗ alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.58 47.0 3.75e-01 91.8% 57.4%
4958192 3718.1.1.34 ↗ alpha bundles › Flagellar protein fliT › Flagellar protein fliT › Flagellar protein fliT › PF26161 0.58 44.0 4.33e-01 82.2% 85.0%
4550967 3843.1.1.29 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › DUF2105 0.57 45.0 4.23e-01 84.9% 70.0%
4242407 7014.1.1.1 ↗ alpha bundles › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › Undecaprenyl pyrophosphate phosphatase (UppP) transmembrane domain › BacA 0.56 45.0 3.55e-01 91.8% 54.1%
3543543 109.59.1.19 ↗ alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Vps16_N 0.54 39.0 3.77e-01 78.1% 92.9%
5065509 601.28.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 0.52 37.0 3.35e-01 78.1% 74.5%
1128224 109.32.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Alkylsulfatase SdsA1 linker domain › Alkylsulfatase SdsA1 linker domain › Alkyl_sulf_dimr 0.52 41.0 3.79e-01 87.7% 67.0%
4964136 3843.1.1.6 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › MrpF_PhaF 0.51 40.0 3.82e-01 86.3% 81.2%
3992117 283.1.1.1 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase › Peptidase_M24 0.51 42.0 3.18e-01 95.9% 91.2%
D4 medium residues 400-437_500-581
PDB
Domain cluster: rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 60.4 2.20e-16 68.3% 16.8%
D5 medium residues 582-657
PDB
Domain cluster: rep: RNA_polymerase__YP_009507833__Tuber_aestivum_virus_1__927810__D565-632
D6 medium residues 658-740
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3cc8A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 41.0 3.15e-01 100.0% 30.3%
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.51 37.0 3.67e-01 84.3% 74.1%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3243984 524.1.1.0 ↗ alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p 0.59 42.0 3.69e-01 84.3% 50.4%
3616953 524.1.1.0 ↗ alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p 0.58 40.0 3.70e-01 84.3% 56.2%
5060698 213.1.1.19 ↗ a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › FR47 0.54 39.0 3.37e-01 80.7% 97.3%
9244 2003.1.2.7 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2 0.51 45.0 3.30e-01 100.0% 88.5%
D7 medium residues 741-802
PDB