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hypothetical_protein_H012_gp259

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

hypothetical_protein_H012_gp259__YP_007354630__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354630 ↗
Protein ID:
hypothetical_protein_H012_gp259
Kingdom:
euk

Quality

70.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 42-124
PDB
Domain cluster: representative
CATH (50)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b7mA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.74 65.0 3.94e-01 100.0% 15.6%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.73 52.0 5.41e-01 74.7% 85.1%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.72 65.0 5.03e-01 100.0% 79.4%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.71 63.0 5.36e-01 98.8% 85.0%
2wgmA01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.70 50.0 5.08e-01 75.9% 81.7%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.69 50.0 4.80e-01 77.1% 94.8%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.67 42.0 4.09e-01 80.7% 56.5%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.67 49.0 4.74e-01 77.1% 69.1%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 49.0 3.58e-01 77.1% 35.8%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.65 46.0 5.02e-01 75.9% 91.0%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.65 39.0 4.31e-01 77.1% 75.8%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.65 46.0 4.79e-01 77.1% 80.5%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.63 51.0 3.44e-01 89.2% 40.9%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 45.0 4.59e-01 77.1% 76.5%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.62 52.0 4.69e-01 97.6% 65.3%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.62 49.0 4.52e-01 86.7% 73.6%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 49.0 4.33e-01 86.7% 89.3%
6wlvB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 53.0 3.87e-01 100.0% 52.0%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 43.0 4.55e-01 74.7% 92.0%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 54.0 5.07e-01 98.8% 95.0%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.61 53.0 4.90e-01 98.8% 93.5%
1sumB02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.61 53.0 4.77e-01 98.8% 82.2%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.61 53.0 4.09e-01 98.8% 82.1%
1sg2A00 3.30.910.20 Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain 0.61 43.0 3.69e-01 75.9% 52.5%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.60 43.0 3.56e-01 77.1% 79.6%
3p8cF01 6.10.140.1620 Special › Helix non-globular › Helix Hairpins › 0.60 46.0 4.28e-01 81.9% 79.0%
1zkeA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 44.0 4.46e-01 77.1% 98.8%
2dfkC01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.60 45.0 3.44e-01 81.9% 78.3%
3b4qA00 1.10.1200.100 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › conserved protein domain from corynebacterium diphtheriae 0.59 44.0 4.33e-01 77.1% 81.6%
2w31A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 49.0 4.06e-01 92.8% 88.8%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.59 43.0 4.53e-01 78.3% 86.7%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 51.0 4.73e-01 100.0% 88.8%
1dxrL02 1.20.85.10 Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like 0.58 42.0 3.86e-01 75.9% 67.6%
1ucuA01 6.10.280.190 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 39.0 4.26e-01 77.1% 85.3%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.57 48.0 4.65e-01 90.4% 80.6%
1tj7A01 1.10.275.10 Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) 0.57 37.0 3.46e-01 75.9% 51.4%
3a98A02 1.20.1270.350 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain 0.57 35.0 3.47e-01 75.9% 57.5%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 48.0 4.20e-01 100.0% 71.3%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 48.0 4.32e-01 98.8% 82.0%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 47.0 4.18e-01 100.0% 76.9%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.55 46.0 4.64e-01 98.8% 89.4%
3dcfA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 47.0 3.95e-01 100.0% 56.3%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 46.0 4.43e-01 100.0% 83.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 44.0 4.35e-01 96.4% 97.8%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.53 45.0 4.49e-01 100.0% 91.0%
3whjA00 6.10.140.1710 Special › Helix non-globular › Helix Hairpins › 0.53 45.0 4.19e-01 98.8% 81.1%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.53 39.0 3.57e-01 79.5% 83.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 44.0 4.04e-01 98.8% 88.3%
3a7mA01 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.52 43.0 3.97e-01 98.8% 71.8%
2zueA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.51 40.0 3.68e-01 90.4% 63.0%
ECOD (53)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4497098 3291.1.1.195 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › H-kinase_dim 0.73 53.0 4.70e-01 77.1% 53.3%
3189817 109.4.1.67 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RINT1_TIP1 0.72 64.0 3.74e-01 100.0% 13.4%
3884349 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.69 51.0 4.41e-01 77.1% 55.2%
4986745 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 57.0 4.44e-01 90.4% 46.7%
4408647 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.67 50.0 4.56e-01 77.1% 67.6%
5047547 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.67 59.0 5.35e-01 100.0% 81.7%
3598168 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.67 48.0 3.81e-01 74.7% 97.0%
4980095 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.66 58.0 5.44e-01 100.0% 99.0%
3229885 4044.1.1.0 alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins 0.66 45.0 4.26e-01 71.1% 59.2%
3768459 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 48.0 3.65e-01 77.1% 44.3%
2429105 4992.1.1.0 extended segments › RelB-like › RelB-like › RelB-like 0.65 47.0 4.95e-01 77.1% 91.9%
5019629 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.65 52.0 4.38e-01 85.5% 74.8%
3520690 627.1.1.2 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › DUF5601 0.65 55.0 5.21e-01 95.2% 94.0%
4146380 4133.1.1.2 alpha arrays › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Emsy N terminal (ENT) domain-like › Tic110 0.64 51.0 4.45e-01 88.0% 70.0%
5074535 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 46.0 4.07e-01 77.1% 90.0%
3983042 3711.1.1.3 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein › Metal_resist 0.62 45.0 4.44e-01 77.1% 74.4%
3471901 3640.1.1.0 alpha duplicates or obligate multimers › Minor ampullate fibroin 1 C-terminal domain › Minor ampullate fibroin 1 C-terminal domain › Minor ampullate fibroin 1 C-terminal domain 0.62 52.0 4.86e-01 92.8% 91.4%
4349607 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.62 46.0 4.21e-01 78.3% 70.0%
3230351 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.62 51.0 4.20e-01 98.8% 47.9%
4547477 601.2.1.5 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr 0.62 44.0 4.06e-01 78.3% 57.3%
3186805 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.61 44.0 4.79e-01 74.7% 88.6%
3423183 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.61 51.0 3.42e-01 92.8% 41.5%
3849157 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.61 45.0 3.91e-01 77.1% 54.4%
3774397 150.5.1.67 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › NEDD4_Bsd2 0.61 47.0 4.59e-01 86.7% 77.9%
3794016 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.61 48.0 3.45e-01 88.0% 91.0%
5077194 191.1.1.0 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain 0.60 48.0 4.31e-01 88.0% 62.2%
5052878 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.60 43.0 4.13e-01 78.3% 65.3%
3859640 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 44.0 3.40e-01 78.3% 34.2%
3528706 192.29.1.11 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.60 45.0 3.95e-01 79.5% 64.8%
4648665 632.7.1.1 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 0.60 40.0 4.04e-01 75.9% 68.2%
5041130 601.14.1.0 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin 0.59 48.0 4.30e-01 92.8% 96.8%
3737296 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.58 43.0 3.77e-01 79.5% 88.5%
3764996 11.2.1.77 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › FerA 0.58 44.0 3.95e-01 81.9% 61.7%
3242356 605.4.1.19 alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF30187 0.58 39.0 3.87e-01 74.7% 64.4%
5004728 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.58 40.0 3.86e-01 74.7% 63.0%
3515526 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.57 50.0 4.29e-01 98.8% 87.4%
3740732 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 49.0 3.54e-01 95.2% 55.4%
5052557 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.57 42.0 3.23e-01 78.3% 86.2%
4568031 191.1.1.2 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_4 0.57 49.0 4.28e-01 100.0% 65.2%
149872 3291.1.1.1 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 0.56 40.0 4.12e-01 75.9% 89.9%
5033071 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.56 39.0 3.75e-01 73.5% 72.0%
4981252 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.56 46.0 4.68e-01 100.0% 100.0%
3617091 622.1.1.17 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › PF29509 0.56 47.0 4.85e-01 90.4% 100.0%
3849547 4992.1.1.25 extended segments › RelB-like › RelB-like › RelB-like › SHCBP_N 0.56 39.0 3.80e-01 77.1% 65.3%
3489528 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 46.0 3.83e-01 96.4% 50.0%
3273217 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.55 46.0 4.50e-01 97.6% 85.3%
4089826 622.1.1.33 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › T3SS_needle_F 0.55 46.0 4.66e-01 98.8% 100.0%
3220199 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.55 46.0 3.81e-01 96.4% 89.7%
3272287 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 39.0 3.76e-01 81.9% 65.0%
3573605 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 40.0 3.15e-01 78.3% 57.7%
3372955 101.1.1.267 alpha arrays › HTH › HTH › Three-helical HTH › PF26138 0.53 36.0 3.20e-01 73.5% 48.3%
3880841 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.53 43.0 3.41e-01 90.4% 77.8%
4027411 3890.1.1.1 alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I 0.52 43.0 3.36e-01 98.8% 80.0%